1986. Other inducible forms metabolize lipophilic xenobiotics into water-soluble compounds
Download 395.86 Kb.
|
Figure 2-3Phylogenetic Analysis of CYP1 Genes using Maximum Parsimony Tree constructed using maximum parsimony with bootstrapping. Most bony fish CYP1A genes are clustered together, as are the bird and mammal CYP1As. The skate CYP1A fragment is most closely associated with the bird and mammal clade. 
References Benedict, J.C., T.M. Lin, I.K. Loeffler, R.E. Peterson, and J.A. Flaws. (2000). Physicological role of the aryl hydrocarbon receptor in mouse ovary development. Toxicol. Sci. 56:382-388. Carrol, R.L. (1988). Vertebrate paleontology and evolution. W.H. Freedman, NY. Colbert, E.H. (1969). Evolution of the Vertebrates. 2d. ed. Wiley, NY. Fernandez-Salguerno, P.M., T. Pineau, D.M. Hilbert, T. McPhail, S.S.T. Lee, S. Kimura, D.W. Nebert, S. Rudikoff, J.M. Ward, and F.J. Gonzales. (1995). Immune system impairment and hepatic fibrosis in mice kacing the dioxin-binding Ah receptor. Science 268:722-726. Fernandez-Salguerno, P.M., J.M. Ward, J.P. Sundberg, and F.J. Gonzales. (1997). Lesions of aryl hydrocarbon receptor deficient mice. Vet. Pathol. 34:605-614. Garfinkel, D. (1958). Studies on pig liver microsomes. I. Enzyme and pigment composition of different microsomal fractions. Arch. Biochem. Biophys. 77: 493-509. Hahn, M.E., A. Poland, E. Glover, and J.J. Stegeman. (1994). Photoaffinity Labeling of the Ah Receptor: Phylogenetic Survey of Diverse Vertebrate and Invertebrate Species. Arch. Biochem. Biophys. 310(1):218-228. Hahn, M.E., B.R. Woodin, J.J. Stegeman, and D.E. Tillitt. (1998). Aryl hydrocarbon receptor function in early vertebrates: Inducibility of cytochrome P450 1A in agnathan and elasmobranch fish. Comp. Biochem. Phys. C 120:67-75. Hahn, M.E. (2002). Aryl hydrocarbon receptors: diversity and evolution. Chemico-Biological Interactions 141: 131. Higgins, D.G. and P.M. Sharp. (1988). Clustal: a package for performing multiple sequence alignment on a microcomputer. Gene 73:237-244. Klingenberg, M. (1958). Pigments of rat liver microsomes. Arch. Biochem. Biophys. 75:376-386. Lahvis, G.P., S.L. Lindell, R.S. Thomas, R.S. McCuskey, C. Murphy, E. Glover, M. Bentz, J. Southard, and C.A. Bradfield. (2000). Portosystemic shunting and persistent fetal vascular structures in aryl hydrocarbon receptor deficient mice. Proc. Natl. Acad. Sci. USA 97:10442-10447. Lemberg, R. and J. Barrett.(1973). Cytochromes. Academic Press, London. Mason, H.S. (1957). Mechanisms of Oxygen Metabolism. Advances in Enzymology 19:79-233. Nelson, J.S. (1994). Fishes of the World. 3d. ed. Wiley, NY. Robles, R., Y. Morita, K.K. Mann, G.I. Perez, S. Yang, T. Matikainen, D.H. Sherr, and J.L. Tilly. (2000). The aryl hydrocarbon receptor, a basic helix-loop-helix transcription factor of the PAS gene family, is required for normal ovarian germ cell dynamics in the mouse. Endocrinology 141:45-453. Said, M.R. (2000). Identification of cytochrome P450 1B-like genes in these teleost species and phylogenetic analysis of CYP1 genes. M.Sci. Thesis. Mass. Instit. Tech.: Div. Bioengin. Enviro. Health. June 2000. Schmidt, J.V., G.H.-T. Su, J.K. Reddy, M.C. Simon, and C.A. Bradfield. (1996). Characterization of a murine Ahr null allele: Involvement of the Ah receptor in hepatic growth and development. Proc. Natl. Acad. Sci. USA 93:6731-6736. Swofford, D.L. (1993). PAUP: Phylogenetic Analysis Using Parsimony. Illinois Natural History Survery. Champaign, IL. Shimada, T. H. Yamazaki, M.Mimura, N. Wakamiya, W.-F. Ueng, F.P. Guengerich, and Y. Inui. (1996). Characterization of microsomal cytochrome P450 enzymes involved in the oxidation of xenobiotic chemicals in human and fetal livers and adult lungs. Drug Metab. Dispos. 24:515-552. Stegeman, J.J. (1993). Diversity and Regulation of Cytochrome P450 in Aquatic Species. Proceedings of the NATO Advanced Study Institute: Molecular Aspects of Oxidative Drug Metabolizing Enzymes: Their Significance in Environmental Toxicology, Chemical Carcinogenesis and Health. Held in Kusadasi, Aydin-Turkey, June 20-July 2, 1993. Editors E. Arinc, J.B. Schlenkman, and E. Hodgson. Thurmond, T.S., J.E. Staples, A.E. Silverstone, and T.A. Gasiewicz. (2001). The aryl hydrocarbon receptor has a role in the in vivo maturation of murine bone marrow B lymphocytes and their response to 2,3,7,8-tetrachlorodibenzo-p-dioxin. Toxico. Appl. Pharma. 171:157-164. Waterman, M.R., M.E. John, and E.R. Simpson. (1986). Regulation of Synthesis and Activity of Cytochrome P450 Enzymes in Physiological Pathways. Cytochrome P450. Structure, Mechanism, and Biochemistry. First Edition, Edited by Paul R. Ortiz de Montellano. Plenum Press, NY. Chapter 10. Yu, M.-H. (2000). Environmental Toxicology: Impacts of Environmental Toxicants on Living Systems. Lewis, Boca Raton, FL. Download 395.86 Kb. Share with your friends:
|