Using both AFB microscopy and NAAT to diagnose MTB infections was more sensitive than using either test alone for both sputum and non-sputum specimens (Figure 24); however, there was a corresponding decrease in specificity when the two tests were combined.
and specificity values for AFB, NAAT and AFB plus NAAT compared with culture according to specimen type" align="bottom" width="602" height="270" border="0">
Figure 24 Forest plot showing the pooled sensitivity and specificity values for AFB, NAAT and AFB plus NAAT compared with culture according to specimen type
and specificity values for AFB, NAAT and AFB plus NAAT compared with culture according to specimen type" align="bottom" width="602" height="270" border="0">