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BIOGRAPHICAL SKETCH








Name: Happi T. Christian

Position/Title: Professor & Dean, College of Postgraduate Studies

Country of Birth: Cameroon

Nationality: Cameroonian

Current Place of Residence: 9, Taxi Way, Aerodrome GRA, Somonda, Ibadan, Nigeria.


Current Working Addresses:


  1. Department of Biological Sciences, College of Natural Sciences, Redeemers’ University, Km 46, Lagos-Ibadan Expressway, Redemption City, Ogun State, Nigeria.




  1. Office of the Dean, College of Postgraduate Studies, Redeemer’s University, Km 46, Lagos-Ibadan Expressway, Redemption City, Ogun State, Nigeria.




Current Employer (s):


  1. Redeemers’ University, Ede, Osun State, Nigeria.




EDUCATION/TRAINING


INSTITUTION AND LOCATION


DEGREE


YEAR(s)

FIELD OF STUDY

Harvard University, School of Public Health, Boston, MA, USA



Postdoctoral Fellow

2000-2003

Molecular Biology

University of Ibadan, Nigeria

PhD

2000

Molecular Parasitology


University of Ibadan, Nigeria


M.Sc

1995

Molecular Parasitology


University of Yaounde, Cameroon


B.Sc (Hons)


1992



Biochemistry



A. Positions and employments
2013-2018- Visiting Professor, Department of Organismic and Evolutionary Biology, Harvard University, Cambridge, Massachusetts, USA.
2012- Present: Dean, College of Postgraduate Studies, Redeemer’s University, Ede, Osun State, Nigeria.
2012- Present: Senior Associate Member, The Broad Institute of Harvard and MIT, Cambridge, Massachusetts, USA.
2011- Present: Professor of Molecular Biology and Genomics, Department of Biological Sciences, College of Natural Sciences, Redeemers’ University, Ede, Osun State, Nigeria.
2011-Present: Inaugural Fellow, Exxon-Mobil Corp, USA, Malaria Leadership Programme, Harvard Malaria Initiative, Harvard University, Boston, MA, USA.
2010-2012: Consultant and Technical Expert, International Atomic Energy Agency, AFRA Programme.
2009-2012: Honorary Senior Research Fellow, Division of Infections and Immunity, School of Medicine, University of Glasgow, Scotland, United Kingdom.
2009-Present: Visiting Professor, Department of Immunology and Infectious Diseases, Harvard School of Public Health, Harvard University, Boston, MA, USA.
2007- present: Adjunct Faculty, Department of Pharmacology and Therapeutics, College of Medicine, University of Ibadan, Ibadan, Nigeria.
2006- Visiting Faculty, Department of Preventive Medicine, Faculty of Medicine, Federal University of Rio de Janeiro, Brazil.
2004-2009: Research Fellow, Department of Immunology and Infectious Diseases, Harvard School of Public Health, Harvard University, Boston, MA, USA.
2003-2012: Committee member and Temporary advisor, WHO/TDR Transfection Technology Network.
2003-2012: Principal Investigator, Malaria Research Laboratories, IMRAT, College of Medicine, University of Ibadan, Nigeria.
2002-2013: Visiting Research Scientist, Division of Experimental Therapeutics, Walter Reed Army Institute of Research, Silver Springs, MD, USA.
2002-2009: Nigerian National Coordinator, International Atomic Energy Agency (IAEA) RAF/0625/UNDP project Monitoring Drug Resistance to Malaria and Tuberculosis.
2001 to 2005: WHO/TDR Molecular Biologist Consultant, MIM/TDR Antimalarial Drugs Resistance Network in Africa.
2000 to 2003: Post-doctoral Research Fellow, Department of Immunology and Infectious Diseases, Harvard School of Public Health, Harvard University, Boston, MA, USA.
1997-2000: Junior Research Fellow, Malaria Research Laboratories, PIMRAT, College of Medicine, University of Ibadan, Nigeria.

B. Honors and Awards.
2014-2018 World Bank Grant Award to establish the African Centre of Excellence of Genomics of Infectious Diseases (ACEGID)
2013-2017 USA, NIH Grant Award to Characterize Fevers of Unknown Origin through Microbial Metagenomics.
2011-2012 Exxon-Mobil Corp. USA, Harvard University Malaria Leadership Programme Award (USA).
2011- 2011, Merle A. Sande Health Leadership Award (Accordia Foundation, USA).
2010-2015 USA, NIAID Grant Award to study Host Genetic Factors in Resistance to Lassa fever.
2010-2014 USA, NIH Grant Award to study Host Pathogen Evolution in Lassa fever.
2010- Scholarship to attend the Second Annual Course on Point-of-Care Diagnostics for Global Health, University of Washington Seattle (USA).
2010- Boroughs Wellcome and Bill & Melinda Gates Awards (USA).
2009-2014 USA, NIAID Grant to study the Roles of Protective or Pathogenic B cell Epitopes in Human Lassa Fever.
2009-2014 Wellcome Trust Research Grant Award (UK).
2009- 2011 European Union-Developing Countries Clinical Trials Partnership (EDCTP) Senior Research Fellowship Award (The Hague, Netherlands).
2008- Chair, Scientific Advisory Committee Africa Health Research Organization (AHRO) (Ghana).
2007-2011 NIH/Fogarty International Centre Research Collaboration Grant Award. (NIH, USA).
2007- Turner Biosciences Research Grant Award (USA).
2005-2008 WHO/TDR Plasmodium falciparum Pathogenesis and Applied Genomics Research Grant Award (World Bank/ UNICEF/WHO/TDR).
2005-2006 International Society of Infectious Diseases (ISID) Research Grant Award (USA).
2004-2005 Research Award for Microarrays Analysis of Plasmodium falciparum Genome (MR4, USA).


  1. Chair, Molecular Parasitology session, 50th Annual Meeting and Anniversary of the American

Society of Tropical Medicine and Hygiene, Philadelphia, Pennsylvania, USA.
2003-2006 NIH/Fogarty International Center Research Collaboration Grant Award (NIH, USA).
2000-2003 WHO/TDR Postdoctoral Research Fellowship Award (World Bank/UNICEF/WHO/TDR).


  1. Award of the Best Postgraduate Student, University of Ibadan (Nigeria).




  1. Wellcome Trust Travel Award to attend the 1st Gordon Conference on Malaria (Oxford, UK).




  1. Award of the Best International Student, University of Ibadan (Nigeria).



    1. Organization of African Unity (OAU), PhD Scholarship Award.




    1. Cameroon Government Scholarship.



C. Membership of Learned Society.
1. Member, Wellcome Trust-CIDRAP Ebola Vaccine Team B (2014)
2.Board Member, African Health Research Organization (AHRO), Ghana
3. Member, USA National Institutes of Health (NIH) International Centers of Infectious Diseases Research (ICIDR) Review Committee. (2014)
3. Member, USA National Institutes of Health (NIH) Centers of Excellence for Translational Research (CETR) Review Committee and Special Emphasis Panel. (2013).
4. Member Steering Committee H3 Africa Consortium
5. Member, International Scientific Advisory Board, Accordia Global Health Foundation, Washington, DC, USA. (2011-2014).
7. Member of the African Academy of Science. (2004-Date)
8. International Scientific Committee Member, 4th Pan-African MIM conference (Cameroon).
9. Member of the Royal Society of Tropical Medicine, UK. (2001-date)
10. Member of the American Society of Tropical Medicine and Hygiene, USA. (2000-date)
11. Foundation member, Worldwide Antimalarial drugs Resistance Network [WWARN] (USA).

D. Peer-Review.
Member of Editorial Board/ Reviewer for Internationally Peer-reviewed Journals including:
1. Acta Tropica (Sweden);

2. African Journal of Medicine and Medical Sciences (Nigeria);

3. American Journal of Tropical Medicine and Hygiene (USA);

4. Annals of Tropical Medicine and Parasitology (UK);

5. Antimicrobial Agents and Chemotherapy (USA);

6. BMC Infectious Diseases (UK);

7. Drug Design, Development and Therapy (USA);

8. Emerging Infectious Diseases (USA);

9. Experimental Parasitology (USA);

10. Infectious Disease News (USA);

11. International Journal of Parasitology (Australia);

12. Journal of Bacteriology and Parasitology (USA);

13. Journal of Infectious Diseases (USA);

14. Journal of Postgraduate Medicine (Canada);

15. Journal of Travel Medicine (USA);

16. Lancet Infectious Diseases (UK);

17. Malaria Journal (UK);

18. Parasitology Research (Germany);

19. Parasitology International (Japan)

20. Pharmacogenetics and Pharmacogenomics (Australia);

21. PLOS Infectious Diseases (USA);

22. PLOS Medicine (USA);

23. PLOS One (USA);

24. The Open Tropical Medicine Journal (USA);

25. The Medical Letter (USA);

26. Transactions of the Royal Society of Tropical Medicine and Hygiene (UK);

27. Tropical Medicine and International Health (UK).

E. Selected Peer-reviewed Publications (in Reverse chronological order).
1. Kristian Graugaard Andersen, B. Jesse Shapiro, Christian B Matranga, Rachel Sealfon, Aaron E Lin, Lina M Moses, Onikepe A Folarin, Augustine Goba, Ikponmwonsa Odia, Philomena E Ehiane, Mambu Momoh, Eleina M England, Sarah Winnicki, Luis M Branco, Stephen K Gire, Eric Phelan, Ridhi Tariyal, Ryan Tewhey, Omowunmi Omoniwa, Mohammed Fullah, Richard Fonnie, Mbalu Fonnie, Lansana Kanneh, Simbirie Jalloh, Michael Gbakie, Sidiki Saffa, Kandeh Karbo, Adrianne D Gladden, James Qu, Matthew Stremlau, Mahan Nekoui, Hilary K Finucane, Shervin Tabrizi, Joseph J Vitti, Bruce Birren, Michael Fitzgerald, Caryn McCowan, Andrea Ireland, Aaron M Berlin, James Bochicchio, Barbara Tazon-Vega, Niall J Lennon, Elizabeth M Ryan, Zach Bjornson, Danny A Milner JR, Amanda K Lukens, Nisha Broodie, Megan Rowland, Megan Heinrich, Marjan Akdag, John S Schieffelin, Danielle Levy, Henry Akpan, Daniel G Bausch, Kathleen Rubins, Joseph B McCormick, Eric S Landers, Stephan Gunther, Lisa Hensley, Sylvanus Okogbenin, Stephen F Schaffner, Peter O Okokhere, S. Humarr Khan, Donald S Grant, George O Akpede, Danny A Asogun, Andreas Gnirke, Joshua Levin, Christian T. Happi, Robert F Garry, Pardis C Sabeti. (2015). Genome-sequencing from clinical and field samples uncovers ancient origins and intra-host evolution of Lassa virus. Cell. (in press).
2. Park DJ, Dudas G, Wohl S, Goba A, Whitmer SLM, Andersen KG, Sealfon RS, Ladner JT, Kugelman JR, Matranga CB, Winnicki SM, Qu J, Gire SK, Gladden-Young A, Jalloh S, Nosamiefan D, Yozwiak NL, Moses L, Jiang P-P, Lin AE, Schaffner SF, Bird B, Towner J, Mamoh M, Gbakie M, Kanneh L, Kargbo D, Massally JLB, Kamara FK, Konuwa E, Sellu J, Jalloh AA, Mustapha I, Foday M, Yillah M, Erickson BR, Sealy T, Blau D, Paddock C, Brault A, Amman B, Basile J, Bearden S, Belser J, Bergeron E, Campbell S, Chakrabarti A, Dodd K, Flint M, Gibbons A, Goodman C, Klena J, Mc- Mullan L, Morgan L, Russell B, Salzer J, Sanchez A, WAng D, Jungreis I, Tomkins-Tinch C, Kislyuk A, Lin MF, Chapman S, MacInnis B, Matthews A, Bochicchio J, Hensley LE, Kuhn JH, Nusbaum C, Scheiffelin JS, Birren BW, Forget M, Nichol ST, Palacios GF, Ndiaye D, Happi C, Gevao SM, Vandi MA, Kargbo B, Holmes EC, Bedford T, Gnirke A, Stroeher U, Rambaut A, Garry RF, Sabeti PC. (2015). Ebola virus epidemiology, transmission, and evolution during seven months in Sierra Leone. Cell. (in press).
3. Matthew H. Stremlau, Kristian G. Andersen, Onikepe A. Folarin, Jessica N. Grove, Ikponmwonsa Odia, Philomena E. Ehiane, Omowunmi Omoniwa, Omigie Omoregie, Pan-Pan Jiang, Nathan L. Yozwiak, Christian B. Matranga, Xiao Yang, Stephen K. Gire, Sarah Winnicki, Ridhi Tariyal, Stephen F. Schaffner, Peter O. Okokhere, Sylvanus Okogbenin, George O. Akpede, Danny A. Asogun, Dennis E. Agbonlahor, Peter J. Walker, Robert B. Tesh, Joshua Z. Levin, Robert F.Garry, Pardis C. Sabeti, and Christian T. Happi. (2015). Discovery of Novel Rhabdoviruses in the Blood of Healthy Individuals from West Africa. PLoS Negl Trop Dis 9(3): e0003631. doi:10.1371/journal.pntd.0003631.

4. Falajiki FY, Akinola O, Abiodun OO, Happi CT, Sowunmi A and Gbotosho GO. (2015). Amodiaquine-Ciprofloxacin: a potential combination therapy against drug resistant malaria. Parasitology. 4: 1-6.

5. Jens H. Kuhn, Kristian G. Andersen, Sylvain BAIZE, Yīmíng Bào, Sina Bavari, Nicolas Berthet, Olga Blinkova, J. Rodney Brister, Anna N. Clawson, Joseph Fair, Martin Gabriel, Robert F. Garry, Stephen K. Gire, Augustine Goba, Jean-Paul Gonzalez, Stephan Günther, Christian T. Happi, Peter B. Jahrling, Jimmy Kapetshi, Gary Kobinger, Jeffrey R. Kugelman, Eric M. Leroy, Gael Darren Maganga, Placide K. Mbala, Lina M. Moses, Jean-Jacques Muyembe-Tamfum, Magassouba N’Faly, Stuart T. Nichol, Sunday A. Omilabu, Gustavo Palacios, Daniel J. Park, Janusz T. Paweska, Sheli R. Radoshitzky, Cynthia A. Rossi, Pardis C. Sabeti, John C. Schieffelin, Randal J. Schoepp, Rachel Sealfon, Robert Swanepoel, Jonathan S. Towner, Jiro Wada, Nadia Wauquier, Nathan L. Yozwiak, Pierre Formenty. (2014). Nomenclature- and database-compatible names for the two Ebola virus variants that emerged in Guinea and the Democratic Republic of the Congo in 2014. Viruses. 6(11):4760-99. doi: 10.3390/v6114760.

6. Matranga CB, Andersen KG, Winnicki S, Busby M, Gladden AD, Tewhey R, Stremlau M, Berlin A, Gire SK, England E, Moses LM, Mikkelsen TS, Odia I, Ehiane PE, Folarin O, Goba A, Kahn S, Grant DS, Honko A, Hensley L, Happi C, Garry RF, Malboeuf CM, Birren BW, Gnirke A, Levin JZ, Sabeti PC. Enhanced methods for unbiased deep sequencing of Lassa and Ebola RNA viruses from clinical and biological samples. Genome Biol. 2014 Nov 18;15(11):519.
7. Onikepe A Folarin, Anise N Happi and Christian T Happi. (2014). Empowering African Genomics for infectious disease control. Genome Biol. 15 (11):515.
8. Schieffelin JS, Shaffer JG, Goba A, Gbakie M, Gire SK, Colubri A, Sealfon RS, Kanneh L, Moigboi A, Momoh M, Fullah M, Moses LM, Brown BL, Andersen KG, Winnicki S, Schaffner SF, Park DJ, Yozwiak NL, Jiang PP, Kargbo D, Jalloh S, Fonnie M, Sinnah V, French I, Kovoma A, Kamara FK, Tucker V, Konuwa E, Sellu J, Mustapha I, Foday M, Yillah M, Kanneh F, Saffa S, Massally JL, Boisen ML, Branco LM, Vandi MA, Grant DS, Happi C, Gevao SM, Fletcher TE, Fowler RA, Bausch DG, Sabeti PC, Khan SH, Garry RF; the KGH Lassa Fever Program, the Viral Hemorrhagic Fever Consortium, and the WHO Clinical Response Team. (2014). Clinica Illness and Outcomes in Patients with Ebola in Sierra Leone. N Eng J Med. 371(22):2092-100. doi: 10.1056/NEJMoa1411680.

9. Kuhn JH, Andersen KG, Bào Y, Bavari S, Becker S, Bennett RS, Bergman NH, Blinkova O, Bradfute S, Brister JR, Bukreyev A, Chandran K, Chepurnov AA, Davey RA, Dietzgen RG, Doggett NA, Dolnik O, Dye JM, Enterlein S, Fenimore PW, Formenty P, Freiberg AN, Garry RF, Garza NL, Gire SK, Gonzalez JP, Griffiths A, Happi CT, Hensley LE, Herbert AS, Hevey MC, Hoenen T, Honko AN, Ignatyev GM, Jahrling PB, Johnson JC, Johnson KM, Kindrachuk J, Klenk HD, Kobinger G, Kochel TJ, Lackemeyer MG, Leroy EM, Lever MS, Mühlberger E, Netesov SV, Olinger GG, Omilabu SA, Palacios G, Panchal RG, Park DJ, Patterson JL, Paweska JT, Peters CJ, Pettitt J, Pitt L, Radoshitzky SR, Ryabchikova EI, Saphire EO, Sabeti PC, Sealfon R, Smither SJ, Sullivan NJ, Swanepoel R, Takada A, Towner JS, van der Groen G, Volchkov VE, Volchkova VA, Wahl-Jensen V, Warren TK, Warfield KL, Weidmann M, Nichol ST, Fackner DF, Shestopalov AM. (2014). Filovirus RefSeq Entries: Evaluation and Selection of Filovirus Type Variants, Type Sequences, and Names. Viruses. 26;6(9):3663-82. doi: 10.3390/v6093663.

10. Gire SK, Goba A, Andersen KG, Sealfon RS, Park DJ, Kanneh L, Jalloh S, Momoh M, Fullah M, Dudas G, Wohl S, Moses LM, Yozwiak NL, Winnicki S, Matranga CB, Malboeuf CM, Qu J, Gladden AD, Schaffner SF, Yang X, Jiang PP, Nekoui M, Colubri A, Coomber MR, Fonnie M, Moigboi A, Gbakie M, Kamara FK, Tucker V, Konuwa E, Saffa S, Sellu J, Jalloh AA, Kovoma A, Koninga J, Mustapha I, Kargbo K, Foday M, Yillah M, Kanneh F, Robert W, Massally JL, Chapman SB, Bochicchio J, Murphy C, Nusbaum C, Young S, Birren BW, Grant DS, Scheiffelin JS, Lander ES, Happi C, Gevao SM, Gnirke A, Rambaut A, Garry RF, Khan SH, Sabeti PC. (2014). Genomic Surveillance elucidates Ebola Virus Origins and Transmission during the 2014 Outbreak. Science. 2014 345(6202):1369-72. doi: 10.1126/science.1259657.

11. Badejo JA, Abiodun OO, Akinola O, Happi CT, Sowunmi A, Gbotosho GO. (2014). Interaction between rifampicin, amodiaquine and artemether in mice infected with chloroquine resistant Plamodium berghei. Malar J. 5;13:299. doi: 10.1186/1475-2875-13-299.

12. Falade MO, Akinboye DO, Gbotosho GO, Ajaiyeoba EO, Happi TC, Abiodun OO, Oduola AM. (2014). In vitro and In vivo Antimalarial Activity of Ficus thonningii Blumes (Moraceae) and Lophira alata banks (Ochnaceae), Indentified from the Ethnomedicine of the Nigerian Middle Belt. J Parasitol Res. 2014;2014:972853. doi: 10.1155/2014/972853.

13. The H3Africa Consortium (2014). Enabling African Scientists for the Genomic Revolution. Science. 344(6190):1346-8. doi: 10.1126/science.1251546

14. Shaffer JG, Grant DS, Schieffelin JS, Boisen ML, Goba A, Hartnett JN, Levy DC, Yenni RE, Moses LM, Fullah M, Momoh M, Fonnie M, Fonnie R, Kanneh L, Koroma VJ, Kargbo K, Ottomassathien D, Muncy IJ, Jones AB, Illick MM, Kulakosky PC, Haislip AM, Bishop CM, Elliot DH, Brown BL, Zhu H, Hastie KM, Andersen KG, Gire SK, Tabrizi S, Tariyal R, Stremlau M, Matschiner A, Sampey DB, Spence JS, Cross RW, Geisbert JB, Folarin OA, Happi CT, Pitts KR, Geske FJ, Geisbert TW, Saphire EO, Robinson JE, Wilson RB, Sabeti PC, Henderson LA, Khan SH, Bausch DG, Branco LM, Garry RF; Viral Hemorrhagic Fever Consortium. Lassa Fever is post-conflict Sierra Leone. (2014). PLoS Negl Trop Dis;8(3):e2748.
15. Agbonlahor DE, Happi C, Igere B, Oviasogie Fe, abbey S, Tatfeng YM, Folarin OA, Ehiaghe JI, Omole E, and Ngialue EA. (2013). Resolution of Disputed Paraentage, Employing Traditional serologic Markers and DNA Short Tandem repeat Multiplex System in Nigeria. Journal of Medical Laboratory Science: 22 (1): 27-33.
16. Akintunde Sowunmi, Grace Olusola Gbotosho, Christian Tientcha Happi, Titilope Okuboyejo, Abayomi Sijuade, Obaro Michael, Elsie O Adewoye, and Onikepe Folarin (2013): Therapeutic Efficacy of Artesunate-Amodiaquine Combinations and the Plasma and Saliva Concentrations of Desethylamodiaquine in Children with Acute Uncomplicated Plasmodium falciparum Malaria. American Journal of Therapeutics: 20(1): 48-56.
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