Drug resistance mediating Plasmodium falciparum polymorphisms and clinical presentations of parasitaemic children in Uganda
Plasmodium falciparum genetic polymorphisms that mediate altered drug sensitivity may impact upon virulence. In a cross-sectional study, Ugandan children with infections mutant at pfcr...
Stephen Tukwasibwe, Patrick Tumwebaze, Melissa Conrad, Emmanuel Arinaitwe, Moses R. Kamya, Grant Dorsey, Samuel L. Nsobya, Bryan Greenhouse and Philip J. Rosenthal
Malaria Journal 2017 16:125
El Niño Southern Oscillation as an early warning tool for malaria outbreaks in India
Risks of malaria epidemics in relation to El Niño and Southern Oscillation (ENSO) events have been mapped and studied at global level. In India, where malaria is a major public health problem, no such effort h...
Ramesh C. Dhiman and Soma Sarkar
Malaria Journal 2017 16:122
False-negative malaria rapid diagnostic tests in Rwanda: impact of Plasmodium falciparum isolates lacking hrp2 and declining malaria transmission
Rapid diagnostic tests (RDTs) for histidine rich protein 2 (HRP2) are often used to determine whether persons with fever should be treated with anti-malarials. However, Plasmodium falciparum parasites with a dele...
Christina T. Kozycki, Noella Umulisa, Stephen Rulisa, Emil I. Mwikarago, Jean Pierre Musabyimana, Jean Pierre Habimana, Corine Karema and Donald J. Krogstad
Malaria Journal 2017 16:123
Age and geographic patterns of Plasmodium falciparum malaria infection in a representative sample of children living in Burkitt lymphoma-endemic areas of northern Uganda
Falciparum malaria is an important risk factor for African Burkitt lymphoma (BL), but few studies have evaluated malaria patterns in healthy BL-age children in populations where both diseases are endemic. To o...
Marlena Maziarz, Tobias Kinyera, Isaac Otim, Paul Kagwa, Hadijah Nabalende, Ismail D. Legason, Martin D. Ogwang, Samuel Kirimunda, Benjamin Emmanuel, Steven J. Reynolds, Patrick Kerchan, Moses M. Joloba, Andrew W. Bergen, Kishor Bhatia, Ambrose O. Talisuna, Robert J. Biggar…
Malaria Journal 2017 16:124
Tryptophan-rich domains of Plasmodium falciparum SURFIN4.2 and Plasmodium vivax PvSTP2 interact with membrane skeleton of red blood cell
Plasmodium falciparum dramatically alters the morphology and properties of the infected red blood cells (iRBCs). A large group of exported proteins participate in these parasite-host i...
Xiaotong Zhu, Yang He, Yifan Liang, Osamu Kaneko, Liwang Cui and Yaming Cao
Malaria Journal 2017 16:121
Erratum to: Pre-travel malaria chemoprophylaxis counselling in a public travel medicine clinic in São Paulo, Brazil
Tânia do Socorro Souza Chaves, Wuelton Marcelo Monteiro, Jessé Reis Alves, Marcus Lacerda and Marta Heloisa Lopes
Malaria Journal 2017 16:120
Clinical and molecular surveillance of drug resistant vivax malaria in Myanmar (2009–2016)
One of the major challenges for control and elimination of malaria is ongoing spread and emergence of drug resistance. While epidemiology and surveillance of the drug resistance in falciparum malaria is being ...
Myat Htut Nyunt, Jin-Hee Han, Bo Wang, Khin Myo Aye, Kyin Hla Aye, Seong-Kyun Lee, Ye Htut, Myat Phone Kyaw, Kay Thwe Han and Eun-Taek Han
Malaria Journal 2017 16:117
Confirmation of Plasmodium falciparum in vitro resistance to monodesethylamodiaquine and chloroquine in Dakar, Senegal, in 2015
In response to increasing resistance to anti-malarial drugs, Senegal adopted artemisinin-based combination therapy (ACT) as the first-line treatment for uncomplicated malaria in 2006. However, resistance of Plasm...
Silman Diawara, Marylin Madamet, Mame Bou Kounta, Gora Lo, Khalifa Ababacar Wade, Aminata Nakoulima, Raymond Bercion, Rémy Amalvict, Mamadou Wague Gueye, Bécaye Fall, Bakary Diatta and Bruno Pradines
Malaria Journal 2017 16:118
Comparison of the diagnostic performance of microscopic examination with nested polymerase chain reaction for optimum malaria diagnosis in Upper Myanmar
Accurate diagnosis of Plasmodium infection is crucial for prompt malaria treatment and surveillance. Microscopic examination has been widely applied as the gold standard for malaria diagnosis in most part of mala...
Jung-Mi Kang, Pyo-Yun Cho, Mya Moe, Jinyoung Lee, Hojong Jun, Hyeong-Woo Lee, Seong Kyu Ahn, Tae Im Kim, Jhang Ho Pak, Moe Kyaw Myint, Khin Lin, Tong-Soo Kim and Byoung-Kuk Na
Malaria Journal 2017 16:119
Unexpected selections of Plasmodium falciparum polymorphisms in previously treatment-naïve areas after monthly presumptive administration of three different anti-malarial drugs in Liberia 1976–78
To assess the effect on malaria prevalence, village specific monthly administrations of pyrimethamine, chlorproguanil, chloroquine or placebo were given to children in four previously treatment-naïve Liberian ...
Irina T. Jovel, Anders Björkman, Cally Roper, Andreas Mårtensson and Johan Ursing
Malaria Journal 2017 16:113
TOLLIP gene variant is associated with Plasmodium vivax malaria in the Brazilian Amazon
Toll-interacting protein is a negative regulator in the TLR signaling cascade, particularly by impeding the TLR2 and, TLR4 pathway. Recently, TOLLIP was shown to regulate human TLR signaling pathways. Two common
Larissa W. Brasil, Laila R. A. Barbosa, Felipe J. de Araujo, Allyson G. da Costa, Luan D. O. da Silva, Suzana K. Pinheiro, Anne C. G. de Almeida, Andrea Kuhn, Sheila Vitor-Silva, Gisely C. de Melo, Wuelton M. Monteiro, Marcus V. G. de Lacerda and Rajendranath Ramasawmy
Malaria Journal 2017 16:116
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