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A comparison of malaria prevalence, control and management strategies in irrigated and non-irrigated areas in eastern Kenya



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A comparison of malaria prevalence, control and management strategies in irrigated and non-irrigated areas in eastern Kenya


This study was conducted in Bura irrigation scheme in Tana River County and the pastoral area in Ijara, Garissa County in the eastern Kenya to establish the knowledge, attitude and practices on malaria transmi...

John Muthii Muriuki, Philip Kitala, Gerald Muchemi, Ian Njeru, Joan Karanja and Bernard Bett

Malaria Journal 2016 15:402

Despite advances in diagnostic technology, significant gaps remain in access to malaria diagnosis. Accurate diagnosis and misdiagnosis leads to unnecessary waste of resources, poor disease management, and cont...

David Bell, Alessandra E. Fleurent, Michael C. Hegg, John D. Boomgard and Caitlin C. McConnico

Malaria Journal 2016 15:406

A framework for evaluating the costs of malaria elimination interventions: an application to reactive case detection in Southern Province of Zambia, 2014


This paper summarizes a framework for evaluating the costs of malaria elimination interventions and applies this approach to one key component of the elimination strategy—reactive case detection (RCD)—implemen...

Bruce A. Larson, Thandiwe Ngoma, Kafula Silumbe, Marie-Reine I. Rutagwera, Busiku Hamainza, Anna M. Winters, John M. Miller and Callie A. Scott

Malaria Journal 2016 15:408

Assessment of Pfs25 expressed from multiple soluble expression platforms for use as transmission-blocking vaccine candidates


Transmission-blocking vaccines (TBVs) have become a focus of strategies to control and eventually eliminate malaria as they target the entry of sexual stage into the Anopheles stephensi mosquito thereby preventin...

Shwu-Maan Lee, Chia-Kuei Wu, Jordan Plieskatt, David H. McAdams, Kazutoyo Miura, Chris Ockenhouse and C. Richter King

Malaria Journal 2016 15:405

The challenge of using intermittent preventive therapy with sulfadoxine/ pyrimethamine among pregnant women in Uganda


The Uganda National Malaria Control Programme recommends the use of intermittent preventive therapy in pregnancy with sulfadoxine/pyrimethamine (SP) to prevent malaria, however, there is overwhelming evidence ...

Humphrey Wanzira, Henry Katamba, Allen Eva Okullo and Denis Rubahika

Malaria Journal 2016 15:401

A qualitative review of implementer perceptions of the national community-level malaria surveillance system in Southern Province, Zambia


Parts of Zambia with very low malaria parasite prevalence and high coverage of vector control interventions are targeted for malaria elimination through a series of interventions including reactive case detect...

Lynne Lohfeld, Tokozile Kangombe-Ngwenya, Anna M. Winters, Zunda Chisha, Busiku Hamainza, Mulakwa Kamuliwo, John M. Miller, Matthew Burns and Daniel J. Bridges

Malaria Journal 2016 15:400

Diagnosis and treatment based on quantitative PCR after controlled human malaria infection


Controlled human malaria infection (CHMI) has become well-established in the evaluation of drugs and vaccines. Anti-malarial treatment is usually initiated when thick blood smears are positive by microscopy. T...

Jona Walk, Remko Schats, Marijke C. C. Langenberg, Isaie J. Reuling, Karina Teelen, Meta Roestenberg, Cornelus C. Hermsen, Leo G. Visser and Robert W. Sauerwein

Malaria Journal 2016 15:398

Direct transfer of HRPII-magnetic bead complexes to malaria rapid diagnostic tests significantly improves test sensitivity


The characteristic ease of use, rapid time to result, and low cost of malaria rapid diagnostic tests (RDTs) promote their widespread use at the point-of-care for malaria detection and surveillance. However, in...

Keersten M. Ricks, Nicholas M. Adams, Thomas F. Scherr, Frederick R. Haselton and David W. Wright

Malaria Journal 2016 15:399

Integrated paediatric fever management and antibiotic over-treatment in Malawi health facilities: data mining a national facility census


There are growing concerns about irrational antibiotic prescription practices in the era of test-based malaria case management. This study assessed integrated paediatric fever management using malaria rapid di...

Emily White Johansson, Katarina Ekholm Selling, Humphreys Nsona, Bonnie Mappin, Peter W. Gething, Max Petzold, Stefan Swartling Peterson and Helena Hildenwall

Malaria Journal 2016 15:396

Anti-erythrocyte antibodies may contribute to anaemia in Plasmodium vivax malaria by decreasing red blood cell deformability and increasing erythrophagocytosis


Plasmodium vivax accounts for the majority of human malaria infections outside Africa and is being increasingly associated in fatal outcomes with anaemia as one of the major complicati...

Luiza Carvalho Mourão, Paula Magda da Silva Roma, Jamila da Silva Sultane Aboobacar, Camila Maia Pantuzzo Medeiros, Zélia Barbosa de Almeida, Cor Jesus Fernandes Fontes, Ubirajara Agero, Oscar Nassif de Mesquita, Marcelo Porto Bemquerer and Érika Martins Braga

Malaria Journal 2016 15:397

Low prevalence of dihydro folate reductase (dhfr) and dihydropteroate synthase (dhps) quadruple and quintuple mutant alleles associated with SP resistance in Plasmodium vivax isolates of West Bengal, India


Emergence of chloroquine resistant Plasmodium vivax is a serious obstacle towards malaria control in India. This study elucidates the temporal pattern of antifolate [sulfadoxine–pyrimethamine (SP)] resistance in

Sabyasachi Das, Abhijit Banik, Amiya Kumar Hati and Somenath Roy

Malaria Journal 2016 15:395

Low prevalence of dihydro folate reductase (dhfr) and dihydropteroate synthase (dhps) quadruple and quintuple mutant alleles associated with SP resistance in Plasmodium vivax isolates of West Bengal, India


Emergence of chloroquine resistant Plasmodium vivax is a serious obstacle towards malaria control in India. This study elucidates the temporal pattern of antifolate [sulfadoxine–pyrimethamine (SP)] resistance in

Sabyasachi Das, Abhijit Banik, Amiya Kumar Hati and Somenath Roy

Malaria Journal 2016 15:395


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