Animal Models of Infarct and Hypoxia
Hall 4
T uesday: 13:30 - 15:30
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1455.
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T1 following Acute Global Cerebral Ischemia in Rats
Dependence on Blood Glucose and Interrelation with Diffusion
Mikko I. Kettunen1, Olli H.J. Gröhn1, Risto A. Kauppinen1
1A.I. Virtanen Institute for Molecular Sciences, University of Kuopio, Kuopio, Finland.
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1456.
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Time Evolution of Cytotoxic and Vasogenic Edema Measured by DWI and T2 in a Porcine Stroke Model
Lisbeth Røhl1, Carsten Gyldensted1, Masaharu Sakoh2, Claus Z Simonsen1, Peter Vestergaard-Poulsen1, Jens C Sørensen1, Leif Østergaard1
1Aarhus University Hospital, Århus, Denmark; 2Ehime University Hospital, Ehime, Japan.
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1457.
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Diffusion and T2 Time Course Changes in a Model of Microsphere Induced Embolic Stroke
Orna Mayzel-Oreg1, Tsuyoshi Omae2, Mark Kazemi3, Fuahi Li2, Marc Fisher2, Yoram Cohen1, Christopher H. Sotak3
1Tel-Aviv University, Tel-Aviv, Israel; 2Umass Memorial Health Care and University of Massachusetts Medical School, Worcester, MA, USA; 3Worcester Polytechnic Institute, Worcester, MA, USA.
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1458.
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A Serial MR Study of Cerebral Blood Flow Changes and Lesion Development Following Endothelin-1 Induced Ischemia in Rats
Richard Buist1, Jeff Biernaskie2, Hao Lei1, Dale Corbett2, James Peeling1
1University of Manitoba, Winnipeg, MB, Canada; 2Memorial University of Newfoundland, St. John's, NF, Canada.
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1459.
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Evaluation of MRI Tissue Signature Changes Between Embolic and Thrombotic Ischemia
Quan Jiang1, Rui Lan Zhang1, Zheng Gang Zhang1, Robert A. Knight1, James R. Ewing1, Jiani Hu2, Qing Jiang Li1, Polly Arniego1, Guang Lian Ding1, Michael Chopp1
1Henry Ford Hospital, Detroit, MI, USA; 2Wayne State University, John R. Harper Hospital, Detroit, MI, USA.
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1460.
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Histopathological Evaluation on Infarct Core, Peri-infarct Border and Intrahemispheric Remote Area in T2 Weighted and Diffusion Weighted MRI Images in the Rat Brain.
Masato Nakane1, Hiroshi Toyama1, Hirofumi Anno1, Masayuki Yamada1, Tatsuhiko Okada1, Kaname Matsumura1, Kazuhiro Katada1, Sukehiko Koga1
1Fujita Health University, Toyoake, Aichi Japan.
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1461.
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Comparison of ADC, CBF and T1 in Arterial Occlusive and Photo-Thrombotic Stroke Models, with Microtubule-Associated Protein-2 (MAP2) Immunoreactivity to Determine the Extent of Ischemia
Donald S. Williams1, Alexander Kharlmov2, Elena Simplaceanu1, Stephen C. Jones2
1Carnegie Mellon University, Pittsburgh NMR Center, Pittsburgh, PA, USA; 2Allegheny General Hospital, Pittsburgh, PA, USA.
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1462.
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Dynamics of Tissue Status Following 1.5-hour Transient Focal Cerebral Ischemia in the Rat, as Measured using T2- and DW-MRI and 1H-MRS
W.B. Veldhuis1, F. Delmas2, P.R. Bär1, K Nicolay1
1University Medical Center, Utrecht, The Netherlands; 2ICSN-CNRS, Gif-sur-Yette, France.
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1463.
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Regional Response of Cerebral Blood Volume to Graded Hypoxia in Rat Brain
Jean-Francois Payen1, Cecile Julien-Dolbec2, Irene Tropres2, Olivier Montigon2, Henri Reutenauer2, Anne Ziegler2, Michel Decorps2
1Johns Hopkins University, Baltimore, MD, USA; 2Hôpital Michallon, Grenoble, France,
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1464.
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Monitoring Cerebrovascular Reserve Capacity Following Bilateral Carotid Artery Occlusion In Rat Using Arterial Spin Tagging Perfusion Imaging
Richard Buist1, Chunliang Wei1, Vyacheslav Volotovsky2, James Peeling1
1University of Manitoba, Winnipeg, MB, Canada; 2National Research Council of Canada, Winnipeg, MB, Canada.
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1465.
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Altered BBB Permeability in Acute Stroke Studied by Gd-DTPA Enhanced T1-weighted Imaging and 14C-
Robert A. Knight1, James R. Ewing1, Taverekere N. Nagaraja1, Vijaya Nagesh1, Polly Arniego1, Susan C. Fagan2, Quan Jiang1, Joseph D. Fenstermacher1
1Henry Ford Hospital, Detroit, MI, USA; 2University of Georgia, Augusta, GA, USA.
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1466.
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Magnetic Resonance Imaging Studies on the Effect of the Antithrombotic Agent Acutobin on Hyperglycemic Rat Middle Cerebral Ischemia/Reperfusion Model
Jingna Wei1, Qingchuang Wang2, Kuangfen Liu2, Michael J Quast1
1University of Texas Medical Branch, Galveston, TX, USA; 2Fujian Medical University, Fuzhou, Fujian P.R.of China.
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1467.
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Does Hypothermia Protect Against "Delayed Tissue Damage" Following a Brief Period of Forebrain Ischemia in the Gerbil?
Mark Lythgoe1, D. L. Thomas2, M. D. King1, Roger Ordidge2, David Gadian1
1Institute of Child Health, London, England, UK; 2University College London, London, England, UK.
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1468.
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Magnesium Treatment Reduces Ischemic Depolarizations and Lesion Volume after Subarachnoid Hemorrhage in the Rat
Walter van den Bergh1
1University Medical Center Utrecht, Utrecht, The Netherlands.
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1469.
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Diffusion MRI of Adult Rat Brain in a Model of Transient Global Ischemia
Rodriguez I.1, D. Alonso1, Jesus Ruiz-Cabello1, J. Serrano1, A. P. Fernandez1, Uttenthal L. O.1, J. Rodrigo1
1Complutense University, Madrid, Spain.
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Animal Brain MR Imaging
Hall 4
Tuesday: 13:30 - 15:30
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1470.
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In Vivo Volume Measurement of Song Control Nuclei in the Brain of European Starlings (Sturnus vulgaris) using Manganese-Enhanced MRI
V. Van Meir1, M. Verhoye1, I. Tindemans1, P. Absil2, J. Balthazart2, A. Van der Linden1
1University of Antwerp, Antwerp, Belgium; 2University of Liège, Liège, Belgium.
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1471.
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Microscopic Parametric Mapping of the Normal Mouse Brain
Todd Ryan Mitchell1, Stanley Thomas Fricke1, Stefan Posse1, Gregory J. Moore1
1Wayne State University, Detroit, MI, USA.
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1472.
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In vivo Tracking of the Neurodegeneration Induced by Intrahippocampal Injections of -Amyloid
Yusuf A. Bhagat1, Andre Obenaus1, J. Steven Richardson1, Edward J. Kendall1
1University of Saskatchewan, Saskatoon, SK, Canada.
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1473.
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Water and Teramethylammonium Diffusion in the Rat Brain with Kaolin-Induced Hydrocephalus
Eva Sykova1, Ivan Vorisek2, Jindrich Fiala1
1Charles University, Prague, Czech Republic; 2Institute of Experimental Medicine ASCR, Prague, Czech Republic.
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1474.
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MRI Tracer Study of Bulk Flow of Interstitial and Cerebrospinal Fluid in a New Hydrocephalus Model
M Shibata1, C-H Nguy2, S Yamada1, M Scadeng1, S Bluml2, JG McComb1, BD Ross3
1Children's Hospital of Los Angeles, Los Angeles, CA, USA; 2Rudi Schulte Research Institute, Santa Barbara, CA, USA; 3Huntington Medical Research Institutes, Pasadena, CA, USA.
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1475.
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Water Diffusion in Myelin Deficient Rat Spinal Cords
Vikas Gulani1, Andrew Webb1, Ian D. Duncan2, Paul Lauterbur1
1University of Illinois at Urbana-Champaign, Urbana, IL, USA; 2University of Wisconsin-Madison, Madison, WI, USA.
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1476.
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Magnetic Resonance Imaging Investigation of a Delayed Type Hypersensitivity Lesion in the Rat Brain.
Kerry A Broom1, Daniel Anthony2, Andrew M Blamire1, Hugh Perry2, Peter Styles1, Nicola R Sibson1
1University of Oxford, Oxford, England, UK; 2Southampton University, Southampton, England, UK.
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1477.
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Measurements of Anatomic and Vascular Characteristics in the Brain of Aging Canine with or without Environmental Enrichment and Antioxidant Diet
M. Y. Su1, E. Head2, J. Wang1, J. Y. Chiou1, H. Yu1, B. A. Muggenburg2, C. W. Cotman1, O. Nalcioglu1
1University of California, Irvine, CA, USA; 2Lovelace Respiratory Research Institute, Albuquerque, NM, USA.
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1478.
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MRI Detection of Early Reductions in Cerebal Perfusion Following Focal Striatal Injection of the Cytokine TNF-: Implications for CNS Disease
Nicola Sibson1, Andrew Blamire1, V. H. Perry2, Peter Styles1, D. C. Anthony2
1University of Oxford, Oxford, England, UK; 2University of Southampton, Highfield, Southampton, UK.
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1479.
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Quantitative DWI Analysis of Neuroprotection Against Soman-Induced Neuropathology
Yusuf A Bhagat1, Andre Obenaus1, Murray G Hamilton2, Edward J Kendall1
1University of Saskatchewan, Saskatoon, Canada; 2Defence Research Establishment Suffield, Medicine Hat, Alberta, Canada.
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1480.
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Kainate Injury in the Rat Brain Evaluated by In Vivo Contrast-Enhanced MRI
Robert Frangez1, Marko Zivin2, Franci Demsar3, Katarina Beravs3
1Veterinary Faculty, Ljubljana, Slovenia; 2Medical Faculty, Ljubljana, Slovenia; 3Jozef Stefan Institute, Ljubljana, Slovenia.
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1481.
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Effects of Centraly Administered Arginine Vasopressin and Atrial Natriuretic Peptide on the Development of Brain Edema in Hyponatremic Rats
Zsolt Vajda1, Michael Pedersen2, Tamás Dóczi3, Endre Sulyok4, Hans Stødkilde-Jørgensen2, Jørgen Frøkiaer1, Søren Nielsen1
1University of Aarhus, Aarhus, Denmark; 2Skejby University Hospital, Aarhus, Denmark; 3Medical School of Pécs, Hungary; 4County Children's Hospital, Pécs, Hungary.
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1482.
|
Bilateral Cortex Over Activation in a Unilateral Rodent Model of Parkinson´s Disease
Galit Pelled1, Hagai Bergman2, Gadi Goelman1
1Hadassh Hebrew University Hospital, Jerusalem, Israel; 2Hadassah Medical School The Hebrew University, Jerusalem, Israel.
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1483.
|
Pharmacological Functional MRI of Psammomys Obesus Brain During Melatonin Stimulation
Inbal Eti Biton1, Alina Neuman1, Nava Zisapel1, Yaniv Assaf1, Yoram Cohen1
1Tel Aviv University, Tel Aviv, Israel.
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1484.
|
High Resolution R2* Mapping of the Belgrade Rat Brain: Role of Divalent Metal Transporter 1(DMT1) in Regional Iron Content
Jeff Bulte1, H. Zywicke1, Peter Van Gelderen1, M. D. Garrick2, K. G. Dolan2, J. R. Burdo3, J. R. Connor3, Joseph Frank1
1National Institutes of Health, Bethesda, MD, USA; 2Pennsylvania State University, Hershey, PA, USA; 3SUNY, Buffalo, NY, USA.
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1485.
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MRS, Water and Tetramethylammonium Diffusion in a Rat Cortex after Traumatic Injury
Ivan Vorisek1, Vít Herynek1, Martin Burian1, Milan Hajek1, Klaas Nicolay2, Eva Sykova3
1Institute of Experimental Medicine ASCR, Prague, Czech Republic; 2University Utrecht, Utrecht, Netherlands; 3Charles University, Prague, Czech Republic.
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1486.
|
In Vivo Imaging of Closed Head Injury in Mice: Automated Analysis Can Document Evidence for the Degree of Recovery Induced by COP-1 Immunization
Uri Nevo1, Jonathan Kipnis2, Esther Shohami3, Solange Akselrod1, Michal Schwartz2
1Tel Aviv University, Tel-Aviv, Israel; 2The Weizmann Institute of Science, Rechovot, Israel; 3The Hebrew University, Jerusalem, Israel.
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1487.
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In Vivo Neuro MRI Microsocopy of Transgenic Mice Overexpressing a Constitutively Active Human Glycogen Synthase Kinase-3b (GSK-3b).
M Verhoye1, K Spittaels2, C Van den Haute2, K Bruynseels2, F Van Leuven2, A Van der Linden1
1University of Antwerp, Antwerp, Belgium; 2Flemish Institute for Biotechnology (VIB), KUL, Leuven, Belgium.
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1488.
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Effects of Ketamine and Ketamine-Xylazine Anesthesia on Cerebral Blood Flow in Rat Observed Using Arterial Spin Tagging Perfusion Imaging
Hao Lei1, Casmier I. Nwaigwe1, Heather Williams1, Jeffrey F. Dunn1
1Dartmouth Medical School, Hanover, NH, USA.
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1489.
|
Dynamic Registration of High Resolution 3-D images from Mouse Brain.
Jean-Philippe Galons1, Alex I. Veress2, Jingyu Guo1, Leena Peltonen3, Lewis L. Lanier4, Jeffrey A. Weiss2, Robert Gillies1
1University of Arizona, Tucson, AZ, USA; 2University of Utah, Salt Lake City, UT, USA; 3UCLA, Los Angeles, CA, USA; 4University of California, San Francisco, San Francisco, CA, USA.
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1490.
|
Integrated T1-T2 Imaging of Water Compartition in Nerve In Vivo
Mark D. Does1, John C. Gore1
1Yale University, School of Medicine, New Haven, CT, USA.
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1491.
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MRI Detection of Cerebral Perfusion and Oxygenation Changes in Pig Brain using Intermolecular Multiple-Quantum Coherences
Margaret Aranda1, Louis-S. Bouchard2, Rahim Rizi1, Ali Asaii1, Mounir Fertikh1, Mitchell D. Schnall1, Warren S. Warren2
1University of Pennsylvania Medical Center, Philadelphia, PA, USA; 2Princeton University, Princeton, NJ, USA.
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1492.
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Functional MRI of Rat Olfactory Glomerulae: Mapping a Single Neuronal Unit
Ikuhiro Kida1, Fahmeed Hyder1, Fuqiang Xu1, Robert Shulman1
1Yale University, New Haven, CT, USA.
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1493.
|
In Vivo 3D Imaging of the Rat Visual Pathway Using Mn2+ as a Tract Tracer
Takashi Watanabe1, Thomas Michaelis1, Jens Frahm1
1Biomed NMR Forschungs GmbH, MPI fur Biophysikalische Chemie, Gottingen, Germany.
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