Title: Journal of Experimental & Clinical Cancer Research

Title: Journal of Experimental & Clinical Cancer Research

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? Zhan, P., Wang, Q., Qian, Q., Wei, S.Z. and Yu, L.K. (2011), CYP1A1 MspI and exon7 gene polymorphisms and lung cancer risk: An updated meta-analysis and review. Journal of Experimental & Clinical Cancer Research, 30, Article Number: 99.

Full Text: 2011\J Exp Cli Can Res30, 99.pdf

Abstract: Background: Many studies have examined the association between the CYP1A1 MspI and exon 7 gene polymorphisms and lung cancer risk in various populations, but their results have been inconsistent. Methods: To assess this relationship more precisely, a meta-analysis and review were performed. The PubMed, Embase, Web of Science, and CNKI database was searched for case-control studies published up to June 2010. Data were extracted and pooled odds ratios (OR) with 95% confidence intervals (CI) were calculated. Results: Ultimately, 64 studies, comprising 18,397 subjects from 49 case-control studies of the MspI genotype and 18,518 patients from 40 case-control studies of the exon 7 genotype, were included. A significantly elevated lung cancer risk was associated with 2 MspI genotype variants (for type C vs Type A: OR = 1.26, 95% CI = 1.12-1.42; for types B and C combined vs Type A: OR = 1.20, 95% CI = 1.13-1.28) in overall population. In the stratified analysis, a significant association was found in Asians, Caucasians, lung SCC, lung AC and Male population, not in mixed population, lung SCLC and Female population. However, inconsistent results were observed for CYP1A1 exon7 in our meta-analysis, two variants of the exon 7 polymorphism were associated with a significantly higher risk for lung cancer (for Val/Val vs Ile/Ile: OR = 1.24, 95% CI = 1.09-1.42; for (Ile/Val +Val/Val) vs Ile/Ile: OR = 1.15, 95% CI = 1.07-1.24) in overall population. In the stratified analysis, a significant assocation was found in Asians, Caucasians, lung SCC and Female population, not in mixed population, lung AD, lung SCLC and Male population. Additionally, a significant association was found in smoker population and not found in non-smoker populations for CYP1A1 MspI and exon7 gene. Conclusions: This meta-analysis suggests that the MspI and exon 7 polymorphisms of CYP1A1 correlate with increased lung cancer susceptibility and there is an interaction between two genotypes of CYP1A1 polymorphism and smoking, but these associations vary in different ethnic populations, histological types of lung caner and gender of case and control population.

Keywords: African-Americans, Analysis, Association, Cancer, Case-Control, Case-Control Studies, Chinese Population, Cigarette-Smoking, Confidence Intervals, Control, Cyp1a1, Environmental Tobacco-Smoke, Female, Gender, Gstm1 Polymorphisms, Gstt1 Genes, Japanese Population, Lung Cancer, Meta Analysis, Meta-Analysis, Methods, North Indian Population, Patients, Polymorphism, Polymorphisms, Pubmed, Review, Risk, S-Transferase Genes, Science, Smoking, Susceptibility, United-States, Web of Science

Title: Journal of Experimental Medicine

Full Journal Title: Journal of Experimental Medicine

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Notes: highly cited (> 1000)

? Boyden, S.V. (1951), The adsorption of proteins on erythrocytes treated with tannic acid and subsequent hemagglutination by antiprotein sera. Journal of Experimental Medicine, 93 (2), 107-120.

Full Text: -1959\J Exp Med93, 107.pdf

Keywords: Acid, Adsorption

? Rossner, M., Van Epps, H. and Hill, E. (2007), Show me the data. Journal of Experimental Medicine, 204 (13), 3052-3053.

Full Text: 2007\J Exp Med204, 3052.pdf

Title: Journal of Experimental Psychology-Applied

Full Journal Title: Journal of Experimental Psychology-Applied

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? Williams, K.M., Nathanson, C. and Paulhus, D.L. (2010), Identifying and profiling scholastic cheaters: Their personality, cognitive ability, and motivation. Journal of Experimental Psychology-Applied, 16 (3), 293-307.

Abstract: Despite much research, skepticism remains over the possibility of profiling scholastic cheaters. However. several relevant predictor variables and newer diagnostic tools have been overlooked. We remedy this deficit with a series of three studies. Study 1 was a large-scale survey of a broad range of personality predictors of self-reported cheating. Significant predictors included the Dark Triad (Machiavellianism. narcissism, psychopathy) as well as low agreeableness and low conscientiousness. Only psychopathy remained significant in a multiple regression. Study 2 replicated this pattern using a naturalistic, behavioral indicator of cheating, namely, plagiarism as indexed by the Internet service Turn-It-In. Poor verbal ability was also an independent predictor. Study 3 examined possible motivational mediators of the association between psychopathy and cheating. Unrestrained achievement and moral inhibition were successful mediators whereas fear of punishment was not. Practical implications for researchers and educators are discussed.

Keywords: Academic Dishonesty, Antisocial, Cheating, Cheating Behavior, College-Students, Construct-Validity, High-School, Individual-Differences, Multiple-Choice Exams, Narcissism, Plagiarism, Psychopathy, Psychopathy, Research, Scholastic Cheating, Self-Report, Survey

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