Experimental Projects: Hardware, Software and Biochemistry
1. (Current) President of Eagle Eye, Inc., a small business based in the Research Triangle, NC. It was originally engaged in reconnaissance multi-spectral image target recognition. EagleEye, Inc. now specializes in contract research in the areas of defense applications of DNA biotechnology. Eagle Eye, Inc. has executed a number of federal research contracts over the last three years. In 2000, Eagle Eye developed (in collaboration with M. Pirrung, Dept of Chemistry, Duke Univ.) a biomolecular system for associative search in pedabit size DNA libraries.
2. DNA Tagging Project(with C. X. Berni, C. Kingsford) We made improvements to SAGE tagging to allow the technology to be applied to universal DNA hybridization arrays. Also, developed simulation software for the improved tagging process with a highly interactive graphic interface.
3. (Previous) Chief scientist of Rtware, 1995-1999, which produces real-time control software which is currently used for both commercial and military applications; military customers include the Airforce and Navy. RTware has received a Phase I SBIR from ONR, It was bought out by Datacode (a large hardware corporation) in 1999.
4. (Previous) President of RSIC Associates, which received a Phase I and Phase II NASA Small Business Innovation Research Grant to build very high rate (.20 gigabit/second) lossless data compression hardware system that was successfully demonstrated. The multiprocessor chip (1.2 micron CMOS with approx. 330,000 transistors and with 128 specialized systolic processor cells per chip) was been fabricated and tested. A number of compression boards, each containing 16 of these chips, have been running since spring, 1992 and can be used by remote login to MCNC. In collaboration with Professor Jim Storer of Brandeis University. VLSI design by Research Triangle Institute, Research Triangle Park, NC in 1989. Board Level Design by MCNC, NC. Also funded by DARPA/ISTO for MOSES fabrication by HP. RSIC Associates has received contracts totaling $1,200,000 from various defense agencies, for the development of this hardware.
5. Co-architect of BLITZEN (with Ed Davis), a 16,000 processor Massively Parallel Machine under NASA contract at Microelectronics Center of North Carolina (MCNC). The main component of the system was a BLITZEN chip, consisting of 128 bit serial processors (.25 gigabits/second). This chip is 1.2 micron CMOS and has 1,100,000 transistors, making it the largest (nonmemory) chip manufactured in the world during early 1989. The chip is tested and functional. A prototype BLITZEN system has been running since spring, 1989. See Publications (references #73,76).
6. Inventor of Holographic Based Message Routing Systems for Massively Parallel Machines. The prototype was constructed under DARPA Contract by Kristina Johnson at the Center for Electro-Optical Computing Systems, Boulder, CO, April 2, 1989. See Publications (reference #80).
7. Implementation (in collaboration with Charles Leiserson, Jill Mesirov, Lena Nekluvova, Steven Omohandro, and Washington Tayler) of Parallel Nested Dissection Algorithms for Solution of Large Sparse Linear Systems on the 64,000 process Connection Machine. Thinking Machines, Inc., Cambridge, MA, 1985-1986. See Publications (reference #62).
8. Implementation (in collaboration with John Dorband and Torstein Opsahl) of Parallel Nested Dissection on 16,000 Processor Massively Parallel Processing Machine (MPP), NASA Goddard Space Center, Greenbelt, MD, 1985-1986. See Publications (reference #63).
Patents -
John H Reif, Peng Yin, Thomas H. LaBean, Geetha Shetty, Erik A. Schultes, Analyte Detection Using Autocatalytic Chain Reactions, US Non-Provisional Patent Application 11/775,740, filed July 10, 2007, publication Date: April 2, 2009. [PDF]. Approved, issued Oct 25, 2011 as US Patent 8,043,810 B2 [GooglePatent][USPO]. Assignee: Eagle Eye Research, Inc.
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John H Reif, Thomas H. LaBean, Erik A. Schultes, Autonomous in Vitro Evolution, US Non-Provisional Patent Application 12/042,276, filed July 10, 2007, publication: September 10, 2009 [GooglePatent][USPO]. Assignee: Eagle Eye Research, Inc.
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John H Reif and Katie L. Reif (joint inventors), "Solar Concentrator System for Solar Energy Plants", US Non-Provisional Patent Application 12/889,313, filed Sept 23, 2010 [GooglePatent][USPO]. Also, Australian Patent number 61/245,250, filed Sept 23, 2009, granted July 24, 2014. Assignee: Eagle Eye Research, Inc.
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John H Reif and Karl F. Bohringer, Microelectronic Devices for Harvesting Vibrational Energy and Associated Systems and Methods, US Provisional Patent Application 61/417,362, filed Nov 29, 2010, published June 7, 2012, US Non-Provisional Patent Application US 12/0139389. Assignee: Ruamoko MEMS, Inc.
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John H Reif, Levitation with switchable inductive element and associated systems, devices, and methods, Provisional Patent Application 61561918, Filed Nov 20, 2011, US Non-Provisional Patent Application No. 13/682,712 filed Nov 20, 2012. Approved Dec 24, 2014. Issued as U.S. Patent No. 9,024,487 on May 5, 2015. Assignee: Eagle Eye Research, Inc. [GooglePatent][USPO].
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John H Reif and Karl F. Bohringer, Microelectronic Devices for Harvesting Vibrational Energy and Associated Systems and Methods, US Provisional Patent Application 61/656,425, filed June 6, 2012. US Non-Provisional Patent Application 13/910,9795, Filed June 5, 2013 [GooglePatent][USPO]. Assignee: Ruamoko MEMS, Inc.
Consulting Positions
1. NASA Johnson Space Flight Center, consultant on Consolidated Space Operations Contract, Houston, Texas, July, 1997.
2. NASA ICASE Space Flight Center, Norfolk, Virginia, July, 1996.
3. NEC research center, Princeton New Jersey, July, 1995.
4. RTware, NC, real time software and algorithms, 1993.
5. Department of Mathematical Sciences, IBM Watson Research Institute. Yorktown Heights, NY, Summers of 1983 and 1984.
6. GTE Laboratories, VLSI Design Project. Waltham, MA, Spring and Summer 1985.
7. Thinking Machines, Inc. Connection Machine Project. Cambridge, MA, 1985-1988.
8. Barakat Associates, Air Force contract: Optical Devices and Optical Computing. Lexington, MA, Fall 1985.
9. MRJ, Park and Elmer, Design of Parallel Algorithms for the Connection Machine. Fairfax, VA, 1985-1988
10.NASA Goddard Space Flight Center, Space Data and Computing Division, Massive Parallel Processing (MPP) Project. Greenbelt, MD, 1985-1988.
11.Microelectronic Center for North Carolina (MCNC), 2nd Generation Massively Parallel Processor Project, (PI of $300,000 NASA contract supporting this work), initiator of and co-architect (with Ed Davis) of BLITZEN 128 processor chip, 1986-1988. (see System Projects #2)
Journals and Book Series Advisory Boards
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Editor, Special Issue on STOC2003, (devoted to selected papers from the 34th Annual ACM Symposium on Theory of Computing (STOC2002), Journal of Computer and System Sciences (JCSS), Volume 67. No. 2, Sept. 2003, pp. 211-471. [PDF]
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Member of Editorial Board of the Journal of Computational and Theoretical Nanoscience (CTN), American Scientific Publishers, USA, 2004-2006.
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Member of Advisory Board, Theory and Practice of Object Systems, Wiley, New York, 2000-2007.
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Member of Editorial Board of the Journal of Experimental Nanoscience, Taylor and Francis, USA, 2006 - current.
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Member of Advisory Board, Series on Natural Computing, Springer-Verlag, 2006 - current.
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Member of Advisory Board, Springer Series in Computer Science and Computer Security for Higher Education Press of Ministry of Education of China, 2009 - current.
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Member of Editorial Advisory Board / DNA and RNA Nanotechnology, 2014 - current
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