Tumor Response to Therapy
Hall 4
M onday: 14:00 - 16:00
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2267.
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Evaluation of Brain Tumor Response to Therapy with 1H MRS, Diffusion and Perfusion MRI: Correlation between Choline Level and ADC, rCBV
Wei Huang1, Patricia Roche1, Alina Tudorica1, Stefan Madajewicz1, Terry M. Button1, H. Li1, J. Manzione1, Clemente Roque1
1State University of New York at Stony Brook, Stony Brook, NY, USA.
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2268.
|
Role of Global Lactate and Dynamic Contrast Imaging in Detecting Response of RIF-1 Tumors to Cyclophosphamide Treatment
Harish Poptani1, Navin Bansal1, Robert Graham1, David Nelson1, Jerry Glickson1
1University of Pennsylvania, Philadelphia, PA, USA.
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2269.
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Early Prediction of Tumor Response to Therapy Using Diffusion Weighted MRI
Yael Mardor1, Thomas Tichler1, Yiftach Roth1, Yael Weiss1, Raanan Berger1, Ami Glicksman1, Rafael Pfeffer1, Roberto Spiegelman1, Jesus Ruiz-Cabello2, Stephan E Maier3, Arie Orenstein1, Jack Cohen1
1Sheba Medical Center, Tel-Hashomer, Israel; 2Universidad Complutense, Madrid, Spain; 3Harvard University, Harvard Medical School, Boston, MA, USA.
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2270.
|
Studies of Ifosfamide and Cyclophosphamide using 31P MRS
GS Payne1, S Vaidya1, F Kinnaird1, CR Pinkerton1, MO Leach1
1Royal Marsden NHS Trust and Institute of Cancer Research, Sutton, Surrey UK.
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2271.
|
Early Assessment by In Vivo 1H-MRS of Tumor Response to Temozolomide in Gliomatosis Cerebri
R. Lodi1, V. Clementi1, P. Cortelli2, L. Crinò3, S. Iotti1, B. Barbiroli1
1Università di Bologna, Bologna, Italy; 2Università di Modena, Italy; 3Ospedale Bellaria, Italy.
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2272.
|
The Relationship between P-31 Metabolites and Oncolytic Viral Therapy Sensitivity in Human Colorectal Cancer Xenografts
Kristen Zakian1, Sandeep Malhotra1, Scarlett Karakash1, Su Xu1, Cornelia Matei1, Yuman Fong1, Jason Koutcher1
1Memorial Sloan Kettering Cancer Center, New York, NY, USA.
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2273.
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Magnetic Resonance Imaging In Vivo - Evaluation of Hepatocellular Carcinomas (HCC) post Gene Therapy (Adenoviral Transfection of Interleukin-12 / B7.1) in Woodchucks
Christoph U. Herborn1, Brigitte M. Puetzer1, Jörg F. Debatin1, Stefan G. Ruehm1
1University Hospital Essen, Essen, Germany.
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2274.
|
Cryo Destruction of Hepa-1 Multicellular Spheroids: A Diffusion Weighted MRI and MR Spectroscopy Study
Catherine Tempel Brami1, Rinat Abramovitch1, Uri Nevo2, Aviv Barzilai3, Yacov Itzchak1, Michal Neeman4, Tammar Kushnir1
1The Chaim Sheba Medical Center, Tel Hashomer, Israel; 2Tel Aviv University, Tel-Aviv, Israel; 3Kaplan Medical Center, Rehovot, Israel; 4Weizmann Institute of Science, Rehovot, Israel.
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2275.
|
Chemotherapy Treatment Assessment using Apparent Diffusion Coefficient Maps
Liz Moore1, Louis Viviers2, Juliet Britton2, Charlotte Absen3, Martin Leach1, Micheal Brada2
1Institute of Cancer Research and The Royal Marsden NHS Trust, Sutton, Surrey, UK; 2The Royal Marsden NHS Trust, Sutton, Surrey, UK; 3Atkinson Morley NHS Trust, London, UK.
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2276.
|
19F MRS study of the Pharmacokinetics of 5-fluorouracil (5-FU) in the Liver of Patients with Colorectal Cancer and Liver Metastases
Yvonne Kamm1, Adrianus Van Den Bergh1, Theo Wagener1, Hanneke Van Laarhoven1, Dennis Klomp1, Arend Heerschap1
1University Medical Centre Nijmegen, Nijmegen, the Netherlands.
|
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2277.
|
Correlation Between the Longitudinal Changes of Tumor Size and the Enhancement Kinetics in Tumors Receiving Gene Therapy
M. Y. Su1, J. Wang1, J. A. Taylor1, L. P. Villarreal1, O. Nalcioglu1
1University of California, Irvine, CA, USA.
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2278.
|
Monitoring Early Response of Human Breast Cancer Xenografts to Taxotere Chemotherapy via 31P MRS and Diffusion MRI
David Morse1, Natarajan Raghunand1, Jean-Philippe Galons1, Robert Gillies1
1University of Arizona, Tucson, AZ, USA.
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Brain Cancer
Hall 4
Wednesday: 13:30 - 15:30
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2279.
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Triple Quantum Filtered 23Na MR Spectroscopy of 9L Glioma in the Presence of Shift Reagent
Patrick M. Winter1, Navin Bansal2
1Washington University School of Medicine, St. Louis, MO, USA; 2University of Pennsylvania, Philadelphia, PA, USA.
|
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2280.
|
Classification of Cerebral Infection and Tumour by Linear Discriminant Analysis of Biopsy Spectra
Theresa Dzendrowskyj1, Roger Bourne1, Uwe Himmelreich1, Carolyn Mountford1, Tania C. Sorrell1
1University of Sydney, Sydney, NSW, Australia.
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2281.
|
Characterization of Intracranial 9L Glioma in Rat Using MR Perfusion and BOLD Imaging at 7T with Carbogen Breathing
Hao Lei1, Julia A. O'Hara1, Huagang Hou1, Carmen M. Wilmot1, Harold M. Swartz1, Jeffrey F. Dunn1
1Dartmouth College, Dartmouth Medical School, Hanover, NH, USA.
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2282.
|
Novel Cell Labeling Strategy for Magnetic Resonance Microimaging of Brain Tumor Invasion In Vivo.
Kenneth Bahk1, P N Venkatasubramanian1, A M Wyrwicz1
1Northwestern University, Evanston, IL, USA.
|
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2283.
|
Improved Analysis of 1H-MR Spectra in the Presence of Mobile Lipids:
Impact on Grading of Malignant Gliomas
Dorothee P. Auer1, Christoff Gössl1, Timo Schirmer2, Michael Czisch1
1Max Planck Institute of Psychiatry, Munich, Germany; 2GE Medical Systems, Buc, France.
|
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2284.
|
Differentiating Types of Human Brain Tumours by MRS. A Comparison of Pre-processing Methods and Echo Times
A. Rosemary Tate1, John R. Griffiths1, Franklyn A. Howe1, Jesus Pujol2, Carles Arús3
1St. George's Hospital Medical School, London, UK; 2Centre Diagnostic Pedralbes, Barcelona, Spain; 3Universitat Autonoma de Barcelona, Cerdanyola del Valles, Spain.
|
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2285.
|
Diffusion Tensor Imaging at 3 Tesla: A Potential Tool for Assessing Occult White Matter Tract Invasion?
Stephen J. Price1, Jonathan H. Gillard1, Neil G. Burnet1, Dylan Pritchard2, Nikos Papadakis2, Kay Martin2, T. Adrian Carpenter2, Tim Donovan2, John D. Pickard1
1Addenbrooke's Hospital, Cambridge, UK; 2University of Cambridge, Cambridge, UK.
|
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2286.
|
Intraindividual Comparison of Contrast Enhancement in Brain Tumors: A Blinded Reader Comparison of a Standard Gd-chelate (Gd-DTPA) vs a Weak Interacting (Gd-BOPTA)
Michael V. Knopp1, Val Runge2, Marco Essig3, Mathias Hartmann4, Olaf Jansen4, Klaus-Peter Lodemann5
1National Institutes of Health, Bethesda, MD, USA; 2University of Kentucky, Georgetown, KY, USA; 3German Cancer Research Centre, Heidelberg, Germany; 4University of Heidelberg, Heidelberg, Germany; 5Bracco-Byk Gulden GmbH, Konstanz, Germany.
|
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2287.
|
Gross-Total Resection of High-Grade Gliomas under Intraoperative MRI-Guidance
Katharina Eberle1, Volker Seifert1, Christos Trantakis1, Jürgen Dietrich1, Thomas Kahn1, Thomas Schulz1, Jens-Peter Schneider1
1University of Leipzig, Leipzig, Germany.
|
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2288.
|
Proton MR Spectroscopy and FDG-PET for the Assessment of Suspicious Lesions after Brain Tumor Radiotherapy
Heinz-Peter Schlemmer1, Marcus Henze2, Klaus Herfarth2, Jürgen Debus1, Peter Bachert3, Gerhard Van Kaick1
1German Cancer Research Center, Heidelberg, Germany; 2University Clinic of Heidelberg, Heidelberg, Germany; 3Schriesheim, Germany.
|
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2289.
|
Semi-Quantative Proton Spectroscopy of Cerebellar Tumor of Childhood
Dongzhu Jin1, Jill V. Hunter1, Zhiyue J. Wang1, Chunpang Shen1, Brendon Tavelli1, Robert A. Zimmerman1
1The Children's Hospital of Philadelphia, Philadelphia, PA, USA.
|
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2290.
|
Automatic Independent Component Analysis of 1H Spectroscopic Imaging Data from Human Brain Tumours
Yrjo Hiltunen1, Juhani Pulkkinen1, Anna-Maija Häkkinen2, Nina Lundbom3, Risto Kauppinen1
1University of Kuopio, A.I. Virtanen Institute, Kuopio, Finland; 2Helsinki, Finland; 3Department of Radiology, Helsinki, Finland.
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2291.
|
Correlation Betwen In Vivo and In Vitro Proton MRS and Histology of Brain Tumors
Tariq Shah1, Rama Jayasunder1, V. P. Singh1, Chitra Sarkar1
1All India Institute of Medical Sciences, Ansari Nagar, New Delhi India.
|
|
2292.
|
Pure Oxygen as a Contrast Medium in Human Brain Tumor MR Imaging.
Christoph Losert1, Michael Peller1, Philipp Schneider1, Martin Thoma1, Martin Busch1, Maximilian Reiser1
1Klinikum Grosshadern, Munich, Germany.
|
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2293.
|
Cost-effectiveness of MRS in the Management of Recurrent Brain Tumors
Alexander Lin1, Maureen Brooks2, Brian Ross1
1Southern California Clinical Spectroscopy Service, Pasadena, CA, USA; 2InSource Medical Solutions, Newport, CA, USA.
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2294.
|
Differentiating Diffuse Brainstem Neoplasms using Proton Magnetic Resonance Spectroscopy
Alexander Lin1, Frederick Shic1, Brian Ross1
1Huntington Medical Research Institutes, Pasadena, CA, USA.
|
|
2295.
|
Analysis of Spatial Extent of the Metabolic Abnormality for Newly Diagnosed Glioma Patients
Xiaojuan Li1, Ying Lu1, Sarah J. Nelson1
1University of California, San Francisco, CA, USA.
|
|
2296.
|
Feature Space Analysis of MRI: Active Brain Tumors versus Radiation Necrosis
H. Soltanian-Zadeh1, L. Smith1, D. J. Peck1, D. O. Hearshen1, L. Scarpace1, T. Mikkelsen1
1Henry Ford Health System, Detroit, MI, USA.
|
|
2297.
|
Diagnostic Value of T1-Weighted Fluid-Attenuated Inversion Recovery Sequence in MR Imaging of Brain Tumors
Fang Zhu1, Liming Xia1, Chengyuan Wang1, Guang Cao2, Jian-Ming Zhu3
1Tongji Hospital, Wuhan, China; 2GE Medical Systems China, Hong Kong, China; 3G. E. Medical Systems, Milwaukee, WI, USA.
|
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2298.
|
Multi-Slice Proton Spectroscopic Imaging of Delayed Radiation Necrosis Correlated with Intraoperative Histology
David Hearshen1, Lisa Scarpace1, Suresh Patel1, Jack P. Rock1, Donald Peck1, Tom Mikkelsen1
1Henry Ford Hospital, Detroit, MI, USA.
|
|
2299.
|
Evaluation of Tumor Oxygenation in Human Brain
Zerrin Yetkin1, Dianne Mendelsohn1, Phillip Purdy1, Roderick McColl1, Ralph P. Mason1
1University of Texas Southwestern Medical Center at Dallas, Dallas, TX, USA.
|
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2300.
|
Correlation of MIB-1 Proliferation Index and Cell Density with Choline Level Using a Quantitative 1H-MRS. Discrepancy in Benign and Malignant Glioma.
Akira Matsumura1, Tomonori Isobe1, Izumi Anno1, Shingo Takano1, Yasushi Nagatomo2, Takashi Yoshizawa3, Yuji Itai1, Tadao Nose1
1University of Tsukuba, Tsukuba, Ibaraki, Japan; 2Seinan-Medical Center, Sakai, Ibaraki, Japan; 3Yokohama Shintoshi Neurosurgical Hospital, Saitama, Japan.
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2301.
|
Diffusion, Perfusion and H1-Spectroscopy in Patients with Newly Diagnosed Gliomas
Isabelle Catalaa1, Roland G Henry1, Edward Graves1, Ying Lu2, Daniel Vigneron1, Sarah J. Nelson1
1University of California, San Francisco, San Francisco, CA, USA.
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2302.
|
Assessment of the Interest of rCBV Mapping for Establishing Differential Diagnosis Between High Grade Gliomas and Other Enhancing Brain Tumors
Stéphane Kremer1, Sylvie Grand1, Chantal Rémy2, Li-Juan Zhou1, Basile Pasquier1, Alim Louis Benabid1, Jean-François Le Bas1
1CHU de Grenoble, Grenoble, France; 2Université J. Fourier, CHU de Grenoble, Grenoble, France.
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2303.
|
Estimation of Local Temperature in Brain Tumors
Rama Jayasundar1, V. P. Singh1
1All India Institute of Medical Sciences, New Delhi, India.
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2304.
|
Characterization of Oligodendrogliomas using Short Echo Time 2D 1H MRSI
M. Rijpkema1, J. Schuuring2, A. Heerschap1
1University Medical Center Nijmegen, Nijmegen, Netherlands.
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2305.
|
Incorporation of 1H Magnetic Resonance Spectroscopic Imaging Data
in the Radiation Treatment Planning Process
Edward E. Graves1, Andrea Pirzkall1, Sarah J. Nelson1, David Larson1, Lynn J. Verhey1
1University of California, San Francisco, CA, USA.
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2306.
|
In Vivo And In Vitro MRS of Central Neurocytomas
Tariq Shah1, Rama Jayasundar1, V. P. Singh1, Chitra Sarkar1
1All India Institute of Medical Sciences, New Delhi, India.
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2307.
|
In Patients with Brain Tumors, Can the Contralateral Brain Hemisphere be Used as Control for Single-Voxel 1H Spectroscopy?
Dirce Takako Fujiwara1, Claudio Campi de Castro2, Sergio Rosemberg2, Marcos Jose Rotta2, Rosa Maria Volpi Piva2, Giovanni Guido Cerri2
1Hospital das Clinicas, Sao Paulo, SP, Brazil; 2University of Sao Paulo, Sao Paulo, SP, Brazil.
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2308.
|
How Accurate is 1H MRS in the Individual Tumor Patient?
Alexander Lin1, Brian Ross1
1Huntington Medical Research Institutes, Pasadena, CA, USA.
|
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2309.
|
Dynamic, Contrast-Enhanced MRI of Murine Gliomas: Correlation with Histology
Soonmee Cha1, Glyn Johnson1, Youssef Zaim Wadghiri1, Olivier Jin1, David Zagzag1, Daniel Turnbull1
1New York University School of Medicine, New York, NY, USA.
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