Of the fifth international conference on bioinformatics


The Fifth International Conference



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The Fifth International Conference
on Bioinformatics of Genome Regulation
and Structure (BGRS'2006)




CONFERENCE PROGRAM

Schedule at a Glance

The Conference Sessions will be held in the Small Conference Hall and in Music Salon

(room no. 220) of the House of Scientists
July 16, Sunday Foyer of the Small Conference Hall

10:00-14:00 Registration of the conference participants*

*Participants who come later are welcome for registration in the Organizing Committee room (House of Scientists, room no.200) on any conference day.
12:30-14:00 Lunch

Small Conference Hall


14:00 Conference Opens:

Welcome by

Academician of the Russian Academy of Sciences Vladimir Shumny, Director of the Institute of Cytology and Genetics, Siberian Branch


of the Russian Academy of Sciences

Greetings of

Corresponding member of the Russian Academy of Sciences, Professor Nikolay Kolchanov and Professor Ralf Hofestaedt


14:30-18:00 PLENAR SESSION

16:00-16:30 Coffee break

19:00-23:00 Welcome party


July 17, Monday Small Conference Hall

9:30-12:45 Morning Session



COMPUTATIONAL STRUCTURAL AND FUNCTIONAL GENOMICS

10:40-11:10 Coffee break

12:45-14:30 Lunch break

14:30-17:45 Evening Session



COMPUTATIONAL STRUCTURAL AND FUNCTIONAL GENOMICS

16:00-16:30 Coffee break



Computer demos of this session will be available during the entire conference day



July 18, Tuesday Small Conference Hall

9:30-12:50 Morning Session



COMPUTATIONAL STRUCTURAL AND FUNCTIONAL PROTEOMICS

10:45-11:15 Coffee break

12:50 -14:30 Lunch break

14:30 -17:25 Evening Session



COMPUTATIONAL STRUCTURAL AND FUNCTIONAL PROTEOMICS

16:05-16:35 Coffee break

Computer demos of this session will be available during the entire conference day



July 19, Wednesday Foyer of the Small Conference Hall

9:30-12:30 POSTER SESSION

10:45-11:15 Coffee break

12:30-14:00 Lunch break


July 20, Thursday Small Conference Hall

9:30-12:55 Morning Session

COMPARATIVE AND EVOLUTIONARY GENOMICS
AND PROTEOMICS


10:45-11:15 Coffee break

12:55-14:30 Lunch break

14:30-18:10 Evening Session

COMPARATIVE AND EVOLUTIONARY GENOMICS
AND PROTEOMICS


16:00-16:30 Coffee break
Computer demos of this session will be available during the entire conference day
July 20, Thursday Music Salon (room no.220)

9:30-12:55 Morning Session



NEW APPROACHES TO BIOMOLECULAR DATA

AND PROCESSES ANALYSIS/Modeling

10:45-11:15 Coffee break

12:55-14:30 Lunch break

14:30-17:20 Evening Session



NEW APPROACHES TO BIOMOLECULAR DATA
AND PROCESSES ANALYSIS/Modeling
16:05-16:30 Coffee break
July 21, Friday Small Conference Hall

9:30-12:55 Morning Session

COMPUTATIONAL SYSTEMS BIOLOGY

10:45-11:15 Coffee break

12:50-14:30 Lunch break


Computer demos of this session will be available during the entire conference day




July 22, Saturday Small Conference Hall

9:30-12:50 Morning Session

COMPUTATIONAL SYSTEMS BIOLOGY

10:45-11:15 Coffee break

12:50-14:30 Lunch break

14:30-16:40 Evening Session



COMPUTATIONAL SYSTEMS BIOLOGY

15:20-15:50 Coffee break



Computer demos of this session will be available during the entire conference day

16:40-17:20 Closing Ceremony; Comments of Session Chairpersons




PLENAR SESSION
July 16, Sunday House of Scientists, Small Conference Hall 14:30-18:00
Co-chairpersons:

Prof. Ralf Hofestaedt, Bielefeld University, AG Bioinformatics, Bielefeld, Germany

Prof. Nikolay Kolchanov, Institute of Cytology and Genetics, Siberian Branch
of the Russian Academy of Sciences, Novosibirsk, Russia


No.

Author(s) and Title of Talk

Timeline

1.

Mazo I. *, Sivachenko A., Yuryev A., Daraselia N.

Ariadne Genomics, Inc., Rockville, USA



Molecular Networks in Mammals: Extraction
from Literature and Microarray

14:30-15:15

2.

Rodin S.N.1*, Rodin A.S.2

1 Beckman Research Institute of the City of Hope, Duarte, CA, USA

2 Human Genetics Center, School of Public Health, University of Texas, Houston, TX, USA

Gene duplications in evolution: From origin
of the genetic code to the human genome

15:15-16:00

Coffee/tea break 16:00-16:30

3.

Ivanov A.S.*, Gnedenko O.V., Molnar A.A., Mezentsev Yu.V., Lisitsa A.V., Archakov A.I.

V.N.Orechovich Institute of Biomedical Chemistry RAMS, Moscow, Russia

PROTEIN-PROTEIN INTERACTIONS AS NEW TARGETS FOR DRUG DESIGN: INTERACTIVE LINKS BETWEEN VIRTUAL
AND EXPERIMENTAL APPROACHES


16:30-17:15

4.

Samsonova M.G.1, Reinitz J.2

1St. Petersburg State Polytechnical University, St. Petersburg, Russia

2 Stony Brook University, Stony Brook, New York, USA

Systems biology of segment determination

17:15-18:00



oral presentations
Dear speakers, please, plan your presentation time including 5 minutes for questions.
Only PowerPoint presentations made in Microsoft Office 2003 or earlier versions can be accepted. Use embedded pictures and animations only; picture and animation links to the Internet or to other files will not be accessible.

Slide projectors or overhead projectors are NOT available during the BGRS'2006 Conference.

Please, take into account that it will not be possible for you to load your presentation during the session by yourselves. Presentations are loaded on the main computer by the technician of the Organizing Committee only.

To ensure that the presentations are well prepared and compatible with the main presentation computer, we strongly advice you to bring your materials as PowerPoint files on USB device or CD disk to the Room no. 200 at the House of Scientists and check the presentation with the technician of the Organizing Committee not later than 30 min before the start time of the session where you are presenting. This will prevent any confusion when loading the presentations on the main computer.

You may also bring your laptop for copying your presentation to the main presentation computer. Use of your own laptop during your presentation is not recommended.

If you have any questions, please do not hesitate to contact the Organizing Committee in Room no. 200 at the House of Scientists.



July 17, Monday House of Scientists, Small Conference Hall
Morning Session

9:30-12:45


COMPUTATIONAL STRUCTURAL AND FUNCTIONAL GENOMICS
and transcriptomics

Co-chairpersons:



Prof. Andrey Mironov, Department of Bioengineering and Bioinformatics, Moscow State University, Moscow, Russia

Dr. Georgii Bazykin, Department of Ecology and Evolutionary Biology, Princeton University, Princeton, NJ, USA


No.

Author(s) and Title of Talk

Timeline

1.

Seliverstov A.V.*, Lyubetsky V.A.

Institute for Information Transmission Problems RAS, Moscow, Russia



Gene expression regulation in Actinobacteria
and Chloroplasts

9:30-

9:55


2.

Grosse I. 1,2


1Leibniz Institute of Plant Genetics and Crop Plant Research (IPK)

2Bioinformatics Center Gatersleben-Halle, Gatersleben, Germany

COMPUTATIONAL IDENTIFICATION OF TRANSCRIPTION FACTOR BINDING SITES WITH VARIABLE ORDER BAYESIAN NETWORKS



9:55-10:20

3.

Levitsky V.G.1,2*, Ignatieva E.V.1,2, Ananko E.A.1, Merkulova T.I.1

1Institute of Cytology and Genetics, SB RAS, Novosibirsk, Russia

2Novosibirsk State University, Novosibirsk, Russia

THE SITEGA AND PWM METHODS APPLICATION
FOR TRANSCRIPTION FACTOR BINDING SITES RECOGNITION
IN EPD PROMOTERS

10:20-10:40

Coffee/tea break 10:40-11:10

4.

Shelest E.S.*1, Wingender E.1,2

1Department of Bioinformatics, UKG, University of Göttingen, Göttingen, Germany

2BIOBASE GmbH, Wolfenbüttel, Germany

PROMOTER MODELING APPROACHES APPLIED TO THE INVESTIGATION OF p63 UP- AND DOWNSTREAM PROMOTERS

11:10-11:35

5.

Vorobjev Y.N., Emelianov D.Y.

Institute of Chemical Biology and Fundamental Medicine, SB RAS, Novosibirsk, Russia



Modeling of data base of context-dependent conformational parameters of DNA duplexes

11:35-12:00

6.

Kamzolova S.G., Osypov A.A.*, Dzhelyadin T.R., Beskaravainy P.M., Sorokin A.A.

Institute of Cell Biophysics of RAS, Pushchino, Moscow region, Russia

CONTEXT-DEPENDENT EFFECTS OF UPSTREAM A-TRACTS
ON PROMOTER ELECTROSTATIC PROPERTIES AND FUNCTION


12:00-12:20

7.

Vishnevsky O.V.1,2*, Konstantinov Yu.M.3

1Institute of Cytology and Genetics, SB RAS, Novosibirsk, Russia

2Novosibirsk State University, Novosibirsk, Russia

3Siberian Institute of Plant Physiology and Biochemistry SB RAS, Irkutsk, Russia

ANALYSIS OF THE NUCLEOTIDE CONTEXT OF HIGHER PLANT MITOCHONDRIAL mRNA EDITING SITES

12:20-12:45


12:45-14:30 Lunch break
July 17, Monday House of Scientists, Small Conference Hall
Evening Session

14:30-18:10


COMPUTATIONAL STRUCTURAL AND FUNCTIONAL GENOMICS
and transcriptomics

Co-chairpersons:



Prof. Vasily Lyubetsky, Institute for Information Transmission Problems,
the Russian Academy of Sciences, Moscow, Russia

Dr. Ivo Grosse, Leibniz Institute of Plant Genetics and Crop Plant Research (IPK) and Bioinformatics Center Gatersleben-Halle, Gatersleben, Germany


No.

Author(s) and Title of Talk

Timeline

1.

Omelianchuk N.A.1, Khomicheva I.V.1, Savinskaya S.A. 1,2, Levitsky V.G.1,2, Vishnevsky O.V. 1,2, Katokhin A.V.1,2, Ponomarenko M.P.1 , Kolchanov N.A.1,2


1Institute of Cytology and Genetics, SB RAS, Novosibirsk, Russia

2 Novosibirsk State University, Novosibirsk Russia

REVEALING THE FUNCTIONAL-SPECIFIC TEXTUAL FEATURES


OF THE microRNA SEQUENCES IN ARABIDOPSIS THALIANA

14:30-14:55

2.

Tutukina M.N., Masulis I.S., Ozoline O.N.*

Institute of Cell Biophysics RAS, Pushchino, Moscow region, Russia


Towards the identification of ANTISENSE RNA
WITHIN GENES OF TRANSCRIPTION REGULATORS


14:55-15:15

3.

Orlov Yu.L.1, Zhou J.1, Lipovich L.1, Yong H.C.2, Li Yi2, Shahab A.2, Kuznetsov V.A.1*

1Genome Institute of Singapore, Singapore

2Bioinformatics Institute, Singapore

A COMPREHENSIVE QUALITY ASSESSMENT OF THE AFFYMETRIX U133A/B PROBESETS BY AN INTEGRATED GENOMIC


AND CLINICAL APPROACH

15:15-15:35

4.

Kuznetsov V.A.*, Zhou J., George J., Orlov Yu.L.

Genome Institute of Singapore, Singapore

GENOME-WIDE CO-EXPRESSION PATTERNS OF HUMAN
CIS-ANTISENSE GENE PAIRS


15:35-16:00

Coffee/tea break 16:00-16:30

5.

Efimov V.M.1*, Badratinov M.S.2, Katokhin A.V.2,3

1Institute of Systematics and Ecology of Animals, SB RAS, Novosibirsk, Russia

2Institute of Cytology and Genetics SB RAS, Novosibirsk, Russia

3Novosibirsk State University, Novosibirsk, Russia

INTERPRETATION OF RESULTS OF SOM ANALYSIS


OF MICROARRAY DATA BY PRINCIPAL COMPONENTS

16:30-16:55

6.

Subkhankulova T., Livesey F.J.

Gurdon Institute and Department of Biochemistry, University of Cambridge, Tennis Court Road, Cambridge, CB2 1 QN, UK



How simIlar Are phenotypically identical cells
at the transcriptional level

16:55-17:20

7.

Abhishek K.1*, Karnick H.1, Mitra P.2

1Indian Institute of Technology Kanpur, Kanpur, India

2Indian Institute of Technology Kharagpur, Kharagpur, India

A KNOWLEDGE AND DATA BASED HYBRID APPROACH
TO GENE CLUSTERING

17:20-17:45


July 18, Tuesday House of Scientists, Small Conference Hall
Morning Session

9:30-12:50

COMPUTATIONAL STRUCTURAL AND FUNCTIONAL PROTEOMICS
Co-chairpersons:

Dr. Kaiser Jamil, Indo American Cancer Institute and Research Center,
Hyderabad, India

Dr. Roman Efremov, M.M. Shemyakin and U.A.Ovchinnikov Institute of Bioorganic Chemistry, the Russian Academy of Sciences, Moscow, Russia


No.

Author(s) and Title of Talk

Timeline

1.

Vlasov P.K.*, Esipova N.G., Tumanyan V.G.

Engelhardt Institute of Molecular Biology, Russian Academy of Sciences, Moscow, Russia

CONFORMATION PROPERTIES OF SHORT OLIGOPEPTIDES
AND PREDICTION OF PROTEIN CHAIN CONFORMATION


9:30-

9:55


2.

Volynsky P.E.*, Vereshaga Ya. A., Nolde D.E., Efremov R.G.

M.M.Shemyakin and Yu.A.Ovchinnikov Institute of Bioorganic Chemistry RAS, Moscow, Russia



Probing dimerization of transmembrane peptides
via molecular dynamics in explicit bilayers

9:55-10:20

3.

Chekmarev S.F.1*, Krivov S.V.2, Karplus M.2,3*

1 Institute of Thermophysics SB RAS, Novosibirsk, Russia

2 Laboratoire de Chimie Biophysique, ISIS, Université Louis Pasteur, Strasbourg, France

3 Department of Chemistry and Chemical Biology, Harvard University, Cambridge, MA, USA

“STRANGE KINETICS” of UBIQUITIN Folding: interpretation in terms of a simple KINETIC MODEL

10:20-10:45

Coffee/tea break 10:45-11:15

4.

Afonnikov D.A.1,2

1 Institute of Cytology and Genetics SB RAS, Novosibirsk, Russia

2 Novosibirsk State University, Novosibirsk, Russia

Residue-residue contact map prediction for proteins

11:15-11:40

5.

Aksianov E.1*, Zanegina O.2, Alexeevski A.3, Karyagina A.4,5, Spirin S.3

1Virology Department, Biological Faculty, Moscow State University, Moscow, Russia

2Bioengineering and Bioinformatics Faculty, Moscow State University, Moscow, Russia

3Belozersky Institute, Moscow State University, Moscow, Russia

4N.F.Gamaleya Research Institute of Epidemiology and Microbiology, Moscow, Russia

5Institute of Agricultural Biotechnology, Moscow, Russia

A TOOL FOR COMPARATIVE ANALYSIS OF SOLVENT MOLECULES IN PDB STRUCTURES

11:40-12:05

6.

Naumoff D.G.

State Institute for Genetics and Selection of Industrial Microorganisms, Moscow, Russia



Development of a hierarchical classification
of the TIM-barrel type glycoside hydrolases

12:05-12:25

7.

Safro M.*1,Tworowski D.1, Feldman A.2

1Department of Structural Biology, Weizmann Institute of Science, Rehovot, Israel

2EML Research gGmbH, Heidelberg, Germany

How are charged residues distributed among functionally distinct structural domains
of aminoacyl-tRNA synthetases?

12:25-12:50



12:50-14:30 Lunch break

July 18, Tuesday House of Scientists, Small Conference Hall
Evening Session

14:30-17:25
COMPUTATIONAL STRUCTURAL AND FUNCTIONAL PROTEOMICS
Co-chairpersons:

Dr. Vladimir Kuznetsov, Genome Institute of Singapore, Singapore



Prof. Sergei Chekmarev, Institute of Thermophysics Siberian Branch
of the Russian Academy of Sciences, Novosibirsk, Russia


No.

Author(s) and Title of Talk

Timeline

1.

Ivanisenko V.A. 1, Demenkov P.S. 2, Fomin E.S. 1, Oshurkov I.S. 3, Korotkov R.O. 3, Aman E.E. 1, Pintus S.S. 1,3, Startcev K.S. 3, Tatarnikova L.Yu. 3, Panina I.I. 3, Sobolev A.A. 3, Seleznev I.V. 3, Elohov V.Yu. 3, Golovina A.N. 3, Aknazarov Z.I. 3, Sharonova I.V. 3, Krestianova M.A. 3, Mishchenko E.L. 1, Magdysuk A.V. 3, Nemiatov A.I. 3

1 Institute of Cytology and Genetics SB RAS, Novosibirsk, Russia

2 Institute of Mathematics SB RAS, Novosibirsk, Russia

3 Novosibirsk State University, Novosibirsk, Russia

FASTPROT: A COMPUTATIONAL WORKBENCH FOR ANALYSIS


OF FUNCTION, ACTIVITY AND STRUCTURE OF PROTEINS

14:30-14:55

2.

Chernorudskiy A.L., Shorina A.S., Garcia A., Gainullin M.R.*

Nizhny Novgorod State Medical Academy, Nizhny Novgorod, Russia



Direct influence of ubiquitylation on a target protein activity: “loss-of-function” mechanism revealed
by computational analysis

14:55-15:20

3.

Demenkov P.S.1*, Aman E.E.2, Ivanisenko V.A.2,3

1Sobolev Institute of Mathematics of the SB RAS, Novosibirsk, Russia

2Institute of Cytology and Genetics SB RAS, Novosibirsk, Russia

3Novosibirsk State University, Novosibirsk, Russia

Prediction in changes of protein thermodynamic stability upon single mutations

15:20-15:40

4.

Kochetov A.V.1*, Sarai A.2, Kolchanov N.A.1

1Institute of Cytology and Genetics, Novosibirsk, Russia

2Kyushu Institute of Technology, Dept. Biochemical Engineering and Science, Iizuka, Japan

THE CONTRIBUTION OF ALTERNATIVE TRANSLATION START SITES TO HUMAN PROTEIN DIVERSITY



15:40-16:05

Coffee/tea break 16:05-16:35

5.

Efremov R.G.

Shemyakin-Ovchinnikov Institute of Bioorganic Chemistry RAS, Moscow, Russia



Computer simulations of peptides and proteins
in membranes: perspectives in drug design

16:35-17:00

6.

Nicklaus M.

Center for Cancer Research, NCI/NIH, Frederick, USA



New Developments at the NIH for Integration of Small-Molecule Databases and Bioinformatics Resources

17:00-17:25



July 20, Thursday House of Scientists, Small Conference Hall
Morning Session

9:30-12:55
COMPARATIVE AND EVOLUTIONARY GENOMICS AND PROTEOMICS
Co-chairpersons:

Dr. Vladimir Kapitonov, Genetic Information Research Institute, Mountain View, California, USA

Dr. Igor Makunin, ARC Special Research Centre for Functional and Applied Genomics, Institute for Molecular Bioscience, University of Queensland, Brisbane, Australia


No.

Author(s) and Title of Talk

Timeline

1.

Vitreschak A.G.1*, Lyubetsky V.A.1, Gelfand M.S.1

1Institute for Information Transmission Problems of RAS, Moscow, Russia

EVOLUTIONAL AND FUNCTIONAL ANALYSIS OF T-BOX REGULON IN BACTERIA. IDENTIFICATION AND CHARACTERIZATION


OF NEW GENES INVOLVED IN AMINO ACID METABOLISM

9:30-

9:55


2.

Bazykin G.A.1*, Dushoff J.1, Levin S.1, Kondrashov A.2

1 Department. of Ecology and Evolutionary Biology, Princeton University, Princeton, NJ, USA

2 National Center for Biotechnology Information, NIH, Bethesda, USA

INSTANCES OF POSITIVE SELECTION AT CONSERVATIVE PROTEIN



9:55-10:20

3.

Gunbin K.V., Suslov V.V., Kolchanov N.A.*

Institute of Cytology and Genetics, SB RAS, Novosibirsk, Russia



AROMORPHOSES AND ADAPTIVE MOLECULAR EVOLUTION: MORPHOGENS AND SIGNALING CASCADE GENES

10:20-10:45

Coffee/tea break 10:45-11:15

4.

Kondrashov F.A.1*, Koonin E.V.2, Morgunov I.G.3, Finogenova T.V.3, Kondrashova M.N.4

1Section on Ecology, Behavior and Evolution, Division of Biological Sciences, University of California at San Diego, La Jolla, USA

2National Center for Biotechnology Information, National Library
of Medicine, National Institutes of Health, Bethesda, USA

3Skryabin Institute of Biochemistry and Physiology of Microorganisms RAS, Pushchino, Russia

4Institute of Theoretical and Experimental Biophysics RAS, Pushchino, Russia

EVOLUTION OF THE GLYOXYLATE CYCLE ENZYMES IN THE METAZOA



11:15-11:40

5.

Ramensky V.1*, Nurtdinov R.2, Neverov A.3, Mironov A. 2, Gelfand M. 2,4

1Engelhardt Institute of Molecular Biology RAS, Moscow, Russia

2Department of Bioengineering and Bioinformatics, Moscow State University, Moscow, Russia

3State Scientific Center GosNIIGenetika, Russia

4Institute for Information Transmission Problems, RAS, Moscow, Russia

HUMAN GENOME POLYMORPHISM AND ALTERNATIVE SPLICING



11:40-12:05

6.

Pintus S.S.1*, Fomin E.S.1, Oshurkov I.S.2, IvanisenkoV.A.1,2*

1Institute of Cytology and Genetics SB RAS, Novosibirsk, Russia

2Novosibirsk State University, Novosibirsk, Russia

phylogenetic analysis of the p53 and p63/p73 gene families

12:05-12:30

7.

Sabitha K. 1, 2, Jamil K.1, 2 *

1Genetics Department, Bhagawan Mahavir Hospital and Research Center, Hyderabad, India

2Indo American Cancer Institute and Research Center, Hyderabad, India

ANALYSIS OF EGFR GENE MUTATIONS WHICH HAVE A RESPONSE TO QUINAZOLIN INHIBITORS



12:30-12:55


12:55-14:30 Lunch break
July 20, Thursday House of Scientists, Small Conference Hall
Evening Session

14:30-18:10
COMPARATIVE AND EVOLUTIONARY GENOMICS AND PROTEOMICS
Co-chairpersons:

Dr. Sergei Rodin, Beckman Research Institute of the City of Hope, Duarte, USA

Dr. Vassily Ramensky, Engelhardt Institute of Molecular Biology, the Russian Academy of Sciences, Moscow, Russia


No.

Author(s) and Title of Talk

Timeline

1.

Ignatieva E.V.*, Oshchepkov D.Yu., Klimova N.V., Vasiliev G.V., Merkulova T.I.

Institute of Cytology and Genetics SB RAS, Novosibirsk, Russia



Analysis of regulatory regions of orthologous genes: prediction of SF1 binding sites with SITECON method proved by experimental verification and comparative genomics

14:30-14:55

2.

Kolesnikov N.N.*, Elisafenko E.A., Zakian S.M.

Institute of Cytology and Genetics SB RAS, Novosibirsk, Russia

EVOLUTION OF THE STRUCTURE OF THE XIST LOCUS
IN MAMMALS


14:55-15:20

3.

Deyneko I.V.*1,2, Kalybaeva Y.M.1, Kel A.E. 3, Blöcker H.*1, Kauer G. 4

1Department of Genome Analysis, GBF, Braunschweig, Germany

2Institute of Cytology and Genetics SB RAS, Novosibirsk, Russia

3BIOBASE GmbH, Wolfenbüttel, Germany

4University of Applied Sciences, Emden, Germany

HUMAN-CHIMPANZEE PROPERTY-DEPENDANT COMPARISONS
ON CHROMOSOMES 21

15:20-15:35

4.

Perelygin A.A.*1, Zharkikh A.A.2, Brinton M.A.1

1 Biology Department, Georgia State University, Atlanta, GA, USA

2 Bioinformatics Department, Myriad Genetics, Inc., Salt Lake City, UT, USA

CONCERTED EVOLUTION OF PARALOGOUS Oas1 GENES


IN RODENTIA AND CETARTIODACTYLA

15:35-16:00

Coffee/tea break 16:00-16:30

5.

Kapitonov V.V.*, Jurka J.

Genetic Information Research Institute, Mountain View, California, USA

NEW KIDS ON THE BLOCK: SELF-SYNTHEsizing DNA TRAnsposons


16:30-16:55

6.

Simons C., Pheasant M., Makunin I.V., Mattick J.S.*

ARC Special Research Centre for Functional and Applied Genomics, Institute for Molecular Bioscience, University of Queensland, Brisbane, Australia



Transposon-free regions in mammalian genomes

16:55-17:20

7.

Golovnina K.1, Glushkov S.*1, Blinov A.1, Mayorov V.2, Adkison L.2 , Goncharov N.1

1Institute of Cytology and Genetics SB RAS, Novosibirsk, Russia

2Mercer University School of Medicine, Macon, USA

MOLECULAR PHYLOGENY OF THE GENUS TRITICUM L.

17:20-17:45

8.

Karafet T. M.1,2*, Lansing J.S.2, Hammer M.F.2

1Institute of Cytology and Genetics SB RAS, Novosibirsk, Russia

2 University of Arizona, Tucson, USA

IN SEARCH OF GENETIC SIGNATURE FOR THE EXPANSION


OF IRRIGATION SYSTEMS IN BALI

17:45-18:10



July 20, Thursday House of Scientists, Music Salon (room no. 200)
Morning Session

9:30-12:55
NEW APPROACHES TO BIOMOLECULAR DATA AND PROCESSES ANALYSIS/MODELING
Co-chairpersons:

Prof. Mikhail Lavrentiev, Jr., Novosibirsk State University, Novosibirsk, Russia

Prof. Vladimir Golubyatnikov, Institute of Mathematics, Siberian Branch
of the Russian Academy of Sciences, Novosibirsk, Russia


No.

Author(s) and Title of Talk

Timeline

1.

Mironov A.A.1,2,3


1Department of Bioengineering and Bioinformatics, Moscow State University, Moscow, Russia

2Institite for Information Transmission Problems, RAS, Moscow, Russia

3State Scientific Center GosNIIGenetica, Russia

Threshold selection using the rank statistics

9:30-

9:55


2.

Hofestaedt R.

Bielefeld University, AG Bioinformatics, Bielefeld, Germany



An Extended Backus-System for the representation
and analysis of DNA sequences

9:55-10:20

3.

Mjolsness E.

Institute for Genomics and Bioinformatics and Departments of Computer Science and Mathematics, University of California, Irvine, USA
MODELING TRANSCRIPTIONAL REGULATION WITH EQUILIBRIUM MOLECULAR COMPLEX COMPOSITION

10:20-10:45

Coffee/tea break 10:45-11:15

4.

Matveeva A.*, Kozlov K., Samsonova M.G.

Department of Computational Biology, Center for Advanced Studies


St. Petersburg State Polytechnical University, St. Petersburg, Russia

METHODOLOGY FOR BUILDING OF COMPLEX WORKFLOWS


WITH PROSTAK PACKAGE AND ISIMBIOS

11:15-11:40

5.

Tatarinova T.1, Schumitzky A.2

1Ceres, Inc. Thousand Oaks, California, USA

2University of Southern California, Los Angeles, USA

MULTIPLE COLLAPSE CLUSTERING



11:40-12:05

6.

Litvinov I. I.1,3*, Finkelshtein A. V.2, Roytberg M. A.1,3*

1Institute of Mathematical Problems in Biology, Russian Academy
of Sciences, Pushchino, Moscow region, Russia

2Institute of Protein Research, Russian Academy of Sciences, Pushchino, Moscow region, Russia

3Pushchino State University, Pushchino, Moscow region, Russia

OPTIMIZATION OF ACCURACY AND CONFIDENCE FOR ALIGNMENT ALGORITHMS EXPLOITING DATA ON SECONDARY STRUCTURE

12:05-12:30

7.

Kozlov K.N.*1, Samsonov A.M.2

1Department of computational biology, State Polytechnical University, St.Petersburg, Russia

2A.F. Ioffe Physico-technical Institute of the Russian Academy of Sciences, St.Petersburg, Russia

NEW MIGRATION SCHEME FOR PARALLEL DIFFERENTIAL EVOLUTION



12:30-12:55


12:55-14:30 Lunch break
July 20, Thursday House of Scientists, Music Salon (room no. 200)
Evening Session

14:30-17:20
NEW APPROACHES TO BIOMOLECULAR DATA AND PROCESSES ANALYSIS/MODELING
Co-chairpersons:

Prof. Mikhail Roytberg, Institute of Mathematical Problems in Biology,
the Russian Academy of Sciences, Pushchino, Moscow Region, Russia

Dr. Andrei Zinovyev, Institute Curie, Bioinformatics Service, Paris, France


No.

Author(s) and Title of Talk

Timeline

1.

Demidenko G.V.*, Matveeva I.I.

Sobolev Institute of Mathematics, SB RAS, Novosibirsk, Russia

ASYMPTOTIC PROPERTIES OF SOLUTIONS OF DIFFERENTIAL-DIFFERENCE EQUATIONS WITH PERIODIC COEFFICIENTS
IN LINEAR TERMS


14:30-14:55

2.

Mateus D.*, Gallois J.P.

CEA/LIST Saclay, F-91191 Gif sur Yvette Cedex, France



Searching constraints in biological regulatory networks using symbolic analysis

14:55-15:20

3.

Labarga A.*, Anderson M., Valentin F., Lopez R.

European Bioinformatics Institute, Hinxton, United Kingdom

WEB SERVICES AT THE EUROPEAN BIOINFORMATICS INSTITUTE


15:20-15:45

4.

Kolpakov F.1,2*, Puzanov M.1,2, Koshukov A.1,2

1Institute of Systems Biology OOO, Novosibirsk, Russia

2Design Technological Institute of Digital Techniques SB RAS, Novosibirsk, Russia

BioUML: visual modeling, automated code generation and simulation of biological systems

15:45-16:05

Coffee/tea break 16:05-16:30

5.

Miginsky D.S.1,2*, Suslov V.V.1, Rasskazov D.A.1,2, Podkolodny N.L.1, Kolchanov N.A.1,2

1Institute of Cytology and Genetics SB RAS, Novosibirsk, Russia

2Novosibirsk State University, Novosibirsk, Russia

ARCHITECTURE OF SOFTWARE TOOLKIT FOR STORING


AND OPERATNG WITH BIOSYSTEMS MODELS

16:30-16:55

6.

Lohmann M.
Cologne University Bioinformatics Center (CUBIC), Cologne, Germany

Metabolomics, Bioinformatics, Systems Biology —
An overview of research and teaching activities
at CUBIC

16:55-17:20


July 21, Friday House of Scientists, Small Conference Hall
Morning Session

9:30-12:55
COMPUTATIONAL SYSTEMS BIOLOGY
Co-chairpersons:

Prof. Eric Mjolsness, Institute for Genomics and Bioinformatics and Departments
of Computer Science and Mathematics, University of California, Irvine, USA

Dr. Bjorn Olsson, School of Humanities and Informatics, University of Skövde, Sweden


No.

Author(s) and Title of Talk

Timeline

1.

Golubyatnikov V.P.1*, Gaidov Yu.A.2, Kleshchev A.G.1, Volokitin E.P.1

1Institute of Mathematics, SB RAS, Novosibirsk, Russia

2Novosibirsk State University, Novosibirsk, Russia

A GENE NETWORK MODEL WITH DIFFERENT TYPES
OF REGULATION

9:30-

9:55


2.

Likhoshvai V.A.

1Institute of Cytology and Genetics SB RAS, Novosibirsk, Russia

Molecular-genetic systems: symmetry of structure
and dynamic chaos

9:55-10:20

3.

Khlebodarova T.M.*, Kachko A.V., Stepanenko I.L., Tikunova N.V.

Institute of Cytology and Genetics SB RAS, Novosibirsk, Russia



DATABASE GenSensor AS INFORMATIONAL SOURCE FOR DESIGN OF BIOSENSORS. EXPERIMENTAL DEVELOPMENT OF BIOSENSOR BASED ON YfiA GENE

10:20-10:45

Coffee/tea break 10:45-11:15

4.

Rapaport F.1,2, Zinovyev A.1,3*, Barillot E.1, Vert J.-P.2

1Institute Curie, Bioinformatics Service, Paris, France

2Ecole des Mines de Paris, Center for Computational Biology,
Fontainebleau, France

3Institute of Computational Modelling SB RAS, Krasnoyarsk, Russia

Spectral analysis of gene expression profiles using gene networks

11:15-11:40

5.

Gunbin К.V.1*, Kogai V.V.2, Fadeev S.I.2, Omelyanchuk L.V.1

1Institute of Cytology and Genetics SB RAS, Novosibirsk, Russia

2Sobolev Institute of Mathematics SB RAS, Novosibirsk, Russia

A MODEL FOR SENSING THE MORPHOGENE HEDGEHOG CONCENTRATION GRADIENT



11:40-12:05

6.

Galimzyanov A.V.

Department of Physicochemical Biology and Epigenetics, Ufa Research Center RAS, Ufa, Russia


GENE NETWORKS BEHAVIOR IN A SERIES OF SUCCESIVE CELL DIVISIONS

12:05-12:30

7.

Milanesi L.*, Alfieri R., Merelli I.

CNR Institute of Biomedical Technologies, Milan, Italy



HCCdb: Data Mining System for Human Cell Cycle Gene

12:30-12:55


12:55-14:30 Lunch break
July 22, Saturday House of Scientists, Small Conference Hall
Morning Session

9:30-12:50
COMPUTATIONAL SYSTEMS BIOLOGY
Co-chairpersons:

Prof. Ralf Hofestaedt, Bielefeld University, AG Bioinformatics, Bielefeld, Germany

Dr. Vyatcheslav Mordvinov, Institute of Cytology and Genetics SB RAS, Novosibirsk, Russia


No.

Author(s) and Title of Talk

Timeline

1.

Omelianchuk N.A.1*, Mironova V.V.1, Poplavsky A.S.1, Pavlov K.S.1,
Savinskaya S.A.2, Podkolodny N.L.1, Mjolsness E.D.3, Meyerowitz E.M.4, Kolchanov N.A.1

1Institute of Cytology and Genetics, SB RAS, Novosibirsk, Russia

2 Novosibirsk State University, Novosibirsk, Russia

3Institute for Genomics and Bioinformatics; University of California, Irvine, USA

4Division of Biology, California Institute of Technology, Pasadena, USA

AGNS (ARABIDOPSIS GENENET SUPPLEMENTARY DATABASE), RELEASE 3.0

9:30-

9:55


2.

Ponomaryov D.1*, Omelianchuk N.2, Mironova V.2, Kolchanov N.2,

Mjolsness E.3, Meyerowitz E.4

1Institute of Informatics Systems, SB RAS, Novosibirsk, Russia

2Institute of Cytology and Genetics, SB RAS, Novosibirsk, Russia

3Institute for Genomics and Bioinformatics, University of California, Irvine, USA

4Division of Biology, California Institute of Technology, Pasadena, USA

A PROGRAM METHOD FOR INFERRING RELATIONSHIPS BETWEEN PHENOTYPIC ABNORMALITIES IN ARABIDOPSIS

9:55-10:20

3.

Akberdin R.*2, Ozonov E.A.1, Mironova V.V.2, Komarov A.V.1, Omelianchuk N.A.2

1Novosibirsk State University, Novosibirsk, Russia

2Institute of Cytology and Genetics SB RAS, Novosibirsk, Russia

A CELLULAR AUTOMATON TO MODEL THE DEVELOPMENT
OF SHOOT MERISTEMS IN ARABIDOPSIS THALIANA

10:20-10:45

Coffee/tea break 10:45-11:15

4.

Nikolaev S.V.1*, Fadeev S.I.2, Penenko A.V.2, Belavskaya V.V.1, Kogay V.V.2, Mjolsness E.3, Kolchanov N.A.1,4

1Institute of Cytology and Genetics, SB RAS, Novosibirsk, Russia

2Institute of Mathematics, SB RAS, Novosibirsk, Russia

3School of Information and Computer Science, and Institute for Genomics
and Bioinformatics, University of California, Irvine, USA

4Novosibirsk State University, Novosibirsk, Russia

CELLULAR-LEVEL MODELLING OF PLANT TISSUE GROWTH
AND MORPHOGENESIS

11:15-11:40

5.

Ratushny A.V.

Institute of Cytology and Genetics, SB RAS, Novosibirsk, Russia

IN SILICO CELL: HIERARCHICAL APPROACH AND GENERALIZED HILL FUNCTION METHOD FOR GENETIC SYSTEMS AND METABOLIC PATHWAYS MODELING

11:40-12:05

6.

Rudenko V.M.*, Korotkov E.V.

Center of Bioengineering RAS, Moscow, Russia

CONSTRUCTION OF THE HCV-HEPATOCYTE SYSTEM MODEL

12:05-12:25

7.

Olsson B.*, Gawronska B., Erlendsson B., Lindlöf A., Dura E.

School of Humanities and Informatics, University of Skövde, Sweden

AUTOMATED TEXT ANALYSIS OF BIOMEDICAL ABSTRACTS APPLIED TO THE EXTRACTION OF SIGNALING PATHWAYS INVOLVED
IN PLANT COLD-ADAPTATION

12:25-12:50


12:50-14:30 Lunch break
July 22, Saturday House of Scientists, Small Conference Hall
Evening Session

14:30-16:40
COMPUTATIONAL SYSTEMS BIOLOGY
Co-chairpersons:

Dr. Luciano Milanesi, CNR Institute of Biomedical Technologies, Milan, Italy

Dr. Mark Lohmann, Cologne University Bioinformatics Center (CUBIC), Cologne, Germany


No.

Author(s) and Title of Talk

Timeline

1.

Aman E.E.1, Demenkov P.S.2, Pintus S.S.3, Nemiatov A.I.3, Apasieva N.V.1, Korotkov R.O. 3, Ignatieva E.V.1, Podkolodny N.L.1, Ivanisenko V.A.*1

1 Institute of Cytology and Genetics, SB RAS, Novosibirsk, Russia

2 Institute of Mathematics, SB RAS, Novosibirsk, Russia

3 Novosibirsk State University, Novosibirsk, Russia

A COMPUTER SYSTEM FOR THE AUTOMATED RECONSTRUCTION OF MOLECULAR-GENETIC INTERACTION NETWORKS

14:30-14:55

2.

Kouznetsova T.N.1*, Ignatieva E.V.1, Oshchepkov D.Yu.1, Kondrakhin Y.V.1, Katokhin A.V.1,2, Shamanina M.Y.1, Mordvinov V.A.1

1Institute of Cytology and Genetics, SB RAS, Novosibirsk, Russia

2Novosibirsk State University, Novosibirsk, Russia

A GENE NETWORK OF ADIPOCYTE LIPID METABOLISM: COORDINATED INTERACTIONS BETWEEN THE TRANSCRIPTION FACTORS SREBP, LXR AND PPAR



14:55-15:20

Coffee/tea break 15:20-15:50

3.

Bezmaternykh K.D.2*, Nikulichev Yu.V.1, Likhoshvai V.A.2,
Matushkin Yu.G.2, Latipov A.F.1, Kolchanov N.A.2

1Institute of Theoretical and Applied Mechanics SB RAS, Novosibirsk, Russia

2Institute of Cytology and Genetics, SB RAS, Novosibirsk, Russia

OPTIMAL CONTROL TASKS IN TERMS OF THE GENE NETWORK MODELS



15:50-16:15

4.

Kolchanov N.A.1*, Orlova G.V.1, Bachinsky A.G.2, Bazhan S.I.2,
Shvarts Ya.Sh.3, Golomolzin V.V.1, Popov D.Yu.1, Efimov V.M.5,
Tololo I.V.6, Ananko E.A.1, Podkolodnaya O.A.1, Il’ina E.N. 4, Rogov S.I. 4, Tretiakov V.E.4, Kubanova A.A.7, Govorun V.M.4

1Institute of Cytology and Genetics, SB RAS, Novosibirsk

2The State Research Center of Virology and Biotechnology “Vector”, Novosibirsk

3Institute of Internal Medicine SB RAMS, Novosibirsk

4Institute of Physical and Chemical Medicine MZ RF, Moscow

5Institute of Animal Taxonomy and Ecology, SB RAS, Novosibirsk
6Institute of Automation and Electrometry, SB RAS, Novosibirsk

7Central Research Institute of Dermatovenerology MZ RF, Moscow

EPI-GIS: GIS ASSISTED COMPUTER TOOLS FOR DATA ACCUMULATION, COMPUTER ANALYSIS AND MODELING


IN MOLECULAR EPIDEMIOLOGY

16:15-16:40


16:40- 17:20 Closing Ceremony. Summaries from session chairpersons
July 19, Wednesday House of Scientists, Small Conference Hall Foyer 9:30-12:30
POSTER SESSION
Poster Size: The maximum size allowed for each poster
is 0.7m wide  1.2m high.

Please note that this is a portrait (vertical) poster.


Authors must bring their posters printed and ready, as no facilities to produce posters at the Conference are available. Organizers will provide boards and push pins to display your posters. Posters should be readable from a distance of about two to three feet—for easy reading by several people at one time.

Presentations may be posted starting from 10:00 on July 17 in the Small Conference Hall Foyer.

The posters will be displayed for the overall duration of the Conference.

A scheduled Poster Session, only one for all Conference sections, will be held on July 19 from 9:30 to 12:30 in the Small Conference Hall Foyer.


During the allotted time, presenters are expected to remain at their individual displays to be available for questions and informal discussion of the poster content.
Material should be removed no later than 13.00 on July 22.

In the case the author(s) does not take away the presentation, it will be removed and destroyed by the BGRS’2006 Organizing Committee.


If you have any questions, please do not hesitate to contact the Organizing Committee
in Room no. 200 at the House of Scientists.


POSTER PRESENTATIONS (by sections)


1. COMPUTATIONAL STRUCTURAL AND FUNCTIONAL GENOMICS
and transcriptomics
Abnizova I.1, Walter K.1, te Boekhorst R.2 , Gilks W.R.1

1Biostatistics Unit MRC, Institute of Public Health, Robinson Way, Cambridge, UK

2University of Hertfordshire, College Lane, Hatfield Campus,UK

NEW WAY TO OBTAIN A REGULATORY MOTIF REPRESENTATION DUE TO MOTIF ABUNDANCE LEVEL


Ananko E.A.*, Kondrakhin Yu.V., Merkulova T.I.

Institute of Cytology and Genetics, SB RAS, Novosibirsk, Russia

PREDICTION OF INTERFERON-INDUCIBLE GENES IN HUMAN GENOME
Apasyeva N.V. 1, Yudin N.S.1*, Ignatieva E.V.1, Voevoda M.I.1,2, Romashenko A.G.1

1Institute of Cytology and Genetics, SB RAS, Novosibirsk, Russia

2 Institute of Intrnal Medicine, SB RAMS, Novosibirsk, Russia

A DATABASE DESIGNED FOR THE POLYMORPHISMS OF THE HUMAN CCR2 GENE
Atambaeva S.A., Ivashchenko A.T.*, Khailenko V., Boldina G., Turmagambetova A.

al-Farabi Kazakh National University, Almaty, Kazakhstan

LENGTH OF EXONS AND INTRONS IN GENES OF SOME HUMAN CHROMOSOMES
Atambaeva S.A., Ivashchenko A.T.*

al-Farabi Kazakh National University, Almaty, Kazakhstan

THE EXONS AND INTRONS LENGTHS IN ARABIDOPSIS THALIANA
AND CAENORHABDITIS ELEGANS GENES
te Boekhorst R.1*, Walter K.2, Elgar G.3, Gilks W.R.2, Abnizova I.2

1University of Hertfordshire, College Lane, Hatfield Campus,UK

2MRC-BSU, Robinson Way, Cambridge, UK

3Queen’s Mary College, London, UK

Statistical characterization of conserved non-coding elements
in VERTEBRATES
Califano A.1, Margolin A.1, Fust A.1, Floratos A.1, Badii B.1, Daly E.1, Kim F.1, Ahmady H.1, Nemenman I.1,2, Watkinson J.1, Wang K.1, Smith K.1, Kustagi M.1, Hall M.1, Banerjee N.1, Morozov P.S.1, Hanasoge S.1, Zhang X.1, Wang X.1, Li Z.1

1Joint Centers for Systems Biology at Columbia University

2Los Alamos National Laboratory, Los Alamos, USA

geWorkbench: a Bioinformatic Platform for Integrated Genomics
Katyshev A.I.1, Rogozin I.B.2, Konstantinov Yu.M.1*

1Siberian Institute of Plant Physiology and Biochemistry, SB RAS, Irkutsk, Russia

2Institute of Cytology and Genetics SB RAS, Novosibirsk, Russia

IDENTIFICATION OF NEW SUPEROXIDE DISMUTASE TRANSCRIPTS IN PLANTS
BY EST ANALYSIS: ALTERNATIVE POLYADENYLATION AND SPLICING EVENTS

Kayumov A.R.*, Kirillova J. M., Mikhailova E. O., Balaban N.P., Sharipova M.R.


Kazan State University, Kazan, Russia

The prediction of regulation of subtilisin-like proteinase gene from Bacillus intermedius through its regulatory sequence analysis
Khomicheva I.V.*, Levitsky V.G., Omelianchuk N.A., Ponomarenko M.P.

Institute of Cytology and Genetics, SB RAS, Novosibirsk, Russia



PATTERN OF LOCALLY POSITIONED DINUCLEOTIDES IN microRNA RELATES
TO ITS ACCUMULATION LEVELS
Khomicheva I.V.1, Levitsky V.G.1, Vishnevsky O.V.1, Savinskaya S.A.2, Omelianchuk N.A.1

1Institute of Cytology and Genetics, SB RAS, Novosibirsk, Russia

2 Novosibirsk State University, Novosibirsk, Russia

IDENTIFICATION OF ARABIDOPSIS THALIANA microRNAs AMONG MPSS SIGNATURES
Khomicheva I.V.*1,2, Vityaev E.E.2, Shipilov T.I.2, Levitsky V.G.1

1Institute of Cytology and Genetics, SB RAS, Novosibirsk, Russia

2Sobolev Institute of Mathematics, SB RAS, Novosibirsk, Russia

TrANSCRIPTION FACTOR BINDING Sites recognition by the ExpertDiscovery SYSTEM BASED ON THE RECURSIVE COMPLEX SYGNALS


Kolchanov N.A.*, Podkolodnaya O.A., Ananko E.A., Ignatieva E.V., Stepanenko I.L., Khlebodarova T.M., Merkulov V.M., Merkulova T.I., Podkolodny N.L., Romashchenko A.G.

Institute of Cytology and Genetics, SB RAS, Novosibirsk, Russia



TRRD: a Database on Experimentally Identified Transcription Regulatory Regions and Transcription Factor Binding Sites
Kondrakhin Yu.V.*, Ananko E.A., Merkulova T.I.

Institute of Cytology and Genetics, SB RAS, Novosibirsk, Russia

METHODS FOR RECOGNITION OF INTERFERON-INDUCIBLE SITES, PROMOTERS,
AND ENHANCERS
Lyubetskaya E.V., Seliverstov A.V.*, Lyubetsky V.A.

Institute for Information Transmission Problems RAS, Moscow, Russia



DETECTING HAiRPINS IN 3’-UNTRANSLATED REGIONS OF HIGHLY EXPRESSED GENES IN ACTINOBACTERIA
Merkulov V.M.*, Merkulova T.I.

Institute of Cytology and Genetics, SB RAS, Novosibirsk, Russia

STRUCTURAL VARIANTS OF BINDING SITES FOR GLUCOCORTICOID RECEPTOR
AND THE MECHANISMS OF GLUCOCORTICOID REGULATION: ANALYSIS OF GR-TRRD DATABASE


Mitra C.K.


School of Life Sciences, University of Hyderabad, Hyderabad, India

STUDIES ON TRANSCRIPTIONAL REGULATION IN DNA



Morozov P.S.1, Morozova I.N.2, Pampou S.2, Shuman H.3, Kalachikov S.M.2

1Joint Centers for Systems Biology, Columbia University, New York, USA

2Columbia Genome Center, Columbia University, New York, USA

3Department of Microbiology, Columbia University, New York, USA

Unique Oligotide Based Microarray Design for the Study of Gene Expression of the Accidental Human Pathogen Legionella pneumophila
Ogurtsov A.Yu.1*, Vasilchenko A.S.2, Vlasov P.K.3, Shabalina S.A.1, Kondrashov A.S.1,
Roytberg M.A.2*

1 National Center for Biotechnology Information, NIH, Bethesda, USA

2 Institute of Mathematical Problems in Biology, Pushchino, Moscow Region, Russia

2 Institute of Molecular Biology, Moscow, Russia

OWEN-SCRIPT – AN EXTENDED TOOL FOR PAIRWISE GENOME ALIGNMENT


Proskura A.L.1*, Levitsky V.G.1,2, Ignatieva E.V.1,2

1Institute of Cytology and Genetics, SB RAS, Novosibirsk, Russia

2Novosibirsk State University, Novosibirsk, Russia

THE ANALYSIS OF SREBP BINDING SITES DISTRIBUTION IN GENE REGIONS
BY COMBINED SITEGA AND PWM APPROACH



Ryazansky S.S.

Institute of Molecular Genetics RAS, Moscow, Russia

IDENTIFICATION OF microRNAs ENCODED BY DROSOPHILA TRASPOSABLE ELEMENTS

Seliverstov A.V.*, Lyubetsky V.A.

Institute for Information Transmission Problems RAS, Moscow, Russia



TRANSLATION REGULATION IN CHLOROPLASTS
Shagimardanova E.I.*, Shamsutdinov T.R., Chastuchina I.B., Sharipova M.R.

Kazan State University, Kazan, Russia

ANALYSIS OF REGULATORY REGION OF BACILLUS INTERMEDIUS GLUTAMYL ENDOPEPTIDASE GENE
Shavkunov K.S. 1, Masulis I.S. 1, Matushkin Yu.G.2, Ozoline O.N.1*

1Institute of Cell Biophysics RAS, Pushchino, Moscow region, Russia

2Institute of Cytology and Genetics, SB RAS, Novosibirsk, Russia

ALTERNATIVE TRANSCRIPTION WITHIN PROCARYOTIC GENES PREDICTED


BY PROMOTER-SEARCH SOFTWARE
Smetanin D.V.*, Chumak N.M.

Krasnodar Research Institute of Agriculture, Krasnodar, Russia



A STEP BEYOND PLANT TRANSCRIPT`S POLYADENYLATION SITE
Smirnova O.G.*, Ibragimova S.S., Grigorovich D.A., Kochetov A.V.

Institute of Cytology and Genetics, SB RAS, Novosibirsk, Russia

TGP (TransGene Promoters): A DATABASE OF BIOTECHNOLOGICALLY IMPORTANT PLANT GENE PROMOTERS
Stavrovskaya E.D.1,2, *, Makeev V.J.3, Merkeev I.V.3, Mironov A.A.1,2,3

1Institute for Information Transmission Problems RAS, Moscow, Russia

2Department of Bioengineering and Bioinformatics, Moscow State University, Moscow, Russia

3State Scientific Center GosNIIGenetica, Moscow, Russia

Tool for automatic detection of co-regulated genes
Taraskina A.S. 1,3, Cheremushkin E.S.2,3

1Mechanics and Mathematics Department, Novosibirsk State University, Novosibirsk, Russia

2Biorainbow Group, Novosibirsk, Russia

3Ershov Institute of Informatics Systems, Novosibirsk, Russia

THE MODIFIED FUZZY C- MEANS METHOD FOR CLUSTERING


OF MICROARRAY DATA
Titov I.I.1,2

1Institute of Cytology and Genetics, SB RAS, Novosibirsk, Russia

2Novosibirsk State University, Russia

THE GArna TOOLBOX FOR RNA STRUCTURE ANALYSIS: THE 2006 STATE


OF THE ART
Titov I.I.1,2*, Ivanisenko A.Yu.2

1Institute of Cytology and Genetics, SB RAS, Novosibirsk, Russia

2Novosibirsk State University, Novosibirsk, Russia

A MODEL OF THE TRANSLATIONAL INHIBITION BY MIRISC COMPLEX DESCRIBES PROTEIN SYNTHESIS VARIATIONS INDUCED BY MUTATIONS IN MAMMALIAN miRNA SITES



Vladimirov N.V. *, Likhoshvai V.A., Matushkin Yu.G.

Institute of Cytology and Genetics, SB RAS, Novosibirsk, Russia

ROLES OF CODON BIASES AND POTENTIAL SECONDARY STRUCTURES
IN mRNA TRANSLATION OF UNICELLULAR ORGANISMS
Vladimirov N.V. *, Kochetov A.V., Grigorovich D.A., Matushkin Yu.G.

Institute of Cytology and Genetics SB RAS, Novosibirsk, Russia

RSCU_COMPARER: A NEW STATISTICAL TOOL FOR PRACTICAL ANALYSIS
OF CODON USAGE
Vityaev Е.E.*1,2, Lapardin K.A.2, Khomicheva I.V.3, Levitsky V.G.2,3

1Institute of Mathematics, SB RAS, Novosibirsk, Russia

2Novosibirsk State University, Novosibirsk, Russia

3Institute of Cytology and Genetics, SB RAS, Novosibirsk, Russia

TRANSCRIPTION FACTOR BINDING SITES RECOGNITION BY THE REGULARITIES MATRICES BASED ON THE NATURAL CLASSIFICATION METHOD


Volod’ko V.B.1, Shuvaev R.Yu.1, Ulyashin A.V.1, Novikova O.S.2, Matushkin Yu.G.2,3

1Novosibirsk Center of Information Technologies "UniPro", Novosibirsk, Russia

2Institute of Cytology and Genetics SB RAS, Novosibirsk, Russia

3Novosibirsk State University, Novosibirsk, Russia

GenomeBrowser – software for visual sequence analysis
Zagoruiko N.G. 1*, Kutnenko O.A. 1, Borisova I.A. 1, Kiselev A.N. 1, Ptitsyn A.A.2

1Institute of Mathematics, SB RAS, Novosibirsk, Russia

2 Pennington Biomedical Research Center, Baton Rouge LA 70808, USA

SELECTION OF INFORMATIVE SUBSET OF GENE EXPRESSION PROFILES


IN PROGNOSTIC ANALYSIS OF TYPE II DIABETES


2. COMPUTATIONAL STRUCTURAL AND FUNCTIONAL PROTEOMICS




Afonnikov D.A.1,2, Morozov A.V.1

1Institute of Cytology and Genetics, SB RAS, Novosibirsk, Russia

2Novosibirsk State University, Novosibirsk, Russia

CONNP: THE PREDICTION OF THE CONTACT NUMBERS OF THE AMINO ACID RESIDUES IN PROTEINS USING NEURAL NETWORK REGRESSION
Aman E.E. *, Demenkov P.S., Ivanisenko V.A.

Institute of Cytology and Genetics, SB RAS, Novosibirsk, Russia



ANALYSIS OF THE TERTIARY STRUCTURE OF THE PPAR AND RXR TRANSCRIPTIONAL FACTORS AND THEIR MUTANT VARIANTS
Bakulina A.Yu.*1, Sineva E.V.2, Solonin A.S.2, Maksyutov A.Z.1

1State Research Center of Virology and Biotechnology “Vector”, Koltsovo, Novosibirsk region, Russia

2Institute of Biochemistry and Physiology of Microorganisms, Russian Academy of Sciences, Pushchino, Moscow region, Russia

MOLECULAR MODELING OF B. CEREUS HEMOLYSIN II, A PORE-FORMING PROTEIN



Baryshev P.B.1*, Afonnikov D.A.1,2, Nikolaev S.V.2

1Novosibirsk State University, Novosibirsk, Russia

2Institute of Cytology and Genetics, SB RAS, Novosibirsk, Russia

Identification and structure-functional analysis of the specificity determining residues of the alpha subunits
of the proteosomal complex
Batsianovsy A.V.*, Vlasov P.K.

Engelhard Institute of Molecular Biology, RAS, Moscow, Russia

*Moscow State University, Moscow, Russia

Clustering analysis of conformational structures
of short oligopeptides
Chugunov A.O.1,2,*, Novoseletsky V.N.1,3, Efremov R.G.1

1Shemyakin-Ovchinnikov Institute of Bioorganic Chemistry, Russian Academy of Sciences, Moscow, Russia

2Department of Bioengineering, Biological Faculty, M.V. Lomonosov Moscow State University, Moscow, Russia

3Moscow Institute of Physics and Technology (State University), Moscow region, Russia

A METHOD TO ASSESS CORRECT/MISFOLDED STRUCTURES OF TRANSMEMBRANE DOMAINS OF MEMBRANE PROTEINS


Efimov A.V., Brazhnikov E.V., Kondratova M.S.


Institute of Protein Research, Russian Academy of Sciences, Pushchino, Moscow region, Russia

effect of the structural context on specificity of intra-
and interhelical interactions in proteins
Dulko V., Feranchuk S.

United Institute of Informatics Problems of the National Academy of Sciences of Belarus,
Minsk, Belarus

Dynamic Programming Algorithm Parallization For Protein Folding
Gou Z., Hwang S., Kuznetsov I.B.*

Gen*NY*sis Center for Excellence in Cancer Genomics, University at Albany, Rensselaer,


USA

SEQUENCE-BASED PREDICTION OF DNA-BINDING SITES ON DNA-BINDING PROTEINS


Ivanisenko V.A.1,2*, Ivanisenko T.V.3, Sharonova I.V.2, Krestyanova M.A.2, Ivanisenko N.V.2, Grigorovich D.A.1

1 Institute of Cytology and Genetics SB RAS, Novosibirsk, Russia

2 Novosibirsk State University, Novosibirsk, Russia

3 Siberian State University of Telecommunications and Information Sciences, Novosibirsk, Russia

PDBSite DATABASE AND PDBSiteScan TOOL: RECOGNITION OF FUNCTIONAL SITES


IN PROTEIN 3d STRUCTURE AND TEMPLATE-BASED DOCKING
Konshina A.G.*, Dubinnyi M.A., Efremov R.G.

Shemyakin–Ovchinnikov Institute of Bioorganic Chemistry, RAS, Moscow, Russia



Structural determinants of cardiotoxins’ membrane binding:
a molecular modeling approach

Nizolenko L.Ph.1*, Bachinsky A.G. 1, Yarygin A.A.1, Naumochkin A.N.1, Grigorovich D.A.2

1SRC VB “Vector”, Koltsovo, Novosibirsk, Russia

2Institute of Cytology and Genetics, SB RAS, Novosibirsk, Russia

PROF_PAT: THE UPDATED DATABASE OF PROTEIN FAMILY PATTERNS.

CURRENT STATUS
Nyporko A.Yu.*, Blume Ya.B.

Institute of Cell Biology and Genetic Engineering of NAS of Ukraine, Kiev, Ukraine

THE FEATURES OF STRUCTURAL DYNAMICS OF DIFFERENT TUBULIN SUBUNITS
Polyansky A.A.*1,2, Aliper E.T.1,2, Volynsky P.E.1, Efremov R.G.1

1M.M. Shemyakin and Yu.A. Ovchinnikov Institute of Bioorganic Chemistry Russian Academy
of Sciences, Moscow, Russia

2Biological Department, M.V.Lomonosov Moscow State University, Moscow, Russia

Action of membrane-active peptides on explicit lipid bilayers. Role
of specific peptide-lipid interactions in membrane destabilization
Pyrkov T.V.*1,2, Kosinsky Yu.A.1, Arseniev A.S.1, Priestle J.P.3, Jacoby E.3, Efremov R.G.1

1M.M. Shemyakin and Yu. A. Ovchinnikov Institute of Bioorganic Chemistry RAS,
Moscow, Russia

2Moscow Institute of Physics and Technology, Moscow, Russia

3Novartis Institutes for Biomedical Research, Basel, Swizerland

COMBINING MOLECULAR DOCKING WITH RECEPTOR DOMAIN MotIONS: SIMULATIONS OF BINDING OF ATP TO CA-ATPASE
Shaytan A.K.*, Khokhlov A.R., Ivanov V.A.

Chair of Polymer and Crystal Physics, Physics Department, Moscow State University,


Moscow, Russia

Pepdite dynamics at water membrane interface
Slyadnikov E.E.

Informatization Problems Department of Tomsk Scientific Centre, SB RAS, Tomsk, Russia



Microscopic model of conformation degrees of freedom cytoskeleton microtubule and its structural analog in optics
Troshin P.V.1*, Papiz M.Z.1, Prince S.M.2, Daniel E.J.3, Morris C.3*, Griffiths S.L.4,
Diprose J.M.5, Pilicheva K.5, Niekerk J.V.6, Pajon A.7

1*Membrane Protein Structure Initiative, CCLRC Daresbury Laboratory, UK
2 Faculty of Life Sciences, University of Manchester, Sackville St., Manchester, UK

3 Protein information Management System, CCLRC Daresbury Laboratory, UK
4York Structural Biology Laboratory, University of York, UK

5Oxford Protein Production Facility, Division of Structural Biology, University of Oxford, UK

6Scottish Structural Proteomics Facility, University of Dundee, UK

7European Bioinformatics Institute, Hinxton, UK

LABORATORY INFORMATION MANAGEMENT SYSTEM FOR MEMBRANE PROTEIN STRUCTURE INITIATIVE


Volkova O.A.1, Kochetov A.V.1*

1Institute of Cytology and Genetics, SB RAS, Novosibirsk, Russia

AMINO ACID PREFERENCES AT THE N-TERMINAL PART OF EUKARYOTIC PROTEINS CORRELATING WITH A SPECIFIC CONTEXTUAL ORGANIZATION OF TRANSLATION INITIATION SIGNAL



3. Comparative and evolutionary genomics AND PROTEOMICS
Babkin I.V.*, Shchelkunov S.N.

State Research Center of Virology and Biotechnology “Vector”, Koltsovo, Novosibirsk region, Russia

Time Scale of Poxvirus Evolution
Boeva V.A.*1, Makeev V.J.2

1Moscow State University, Department of Bioengineering and Bioinformatics, Moscow, Russia

2GosNIIGenetika State Research Center, Moscow, Russia

Micro- and Minisatellites in Human genome, Tandemswan software
in use
Brinza D., Perelygin A., Brinton M., Zelikovsky A.*

Georgia State University, Atlanta, USA

SEARCH FOR MULTI-SNP DISEASE ASSOCIATION
Bukin Y.S.*, Pudovkina T.A.

Limnological Institute of SB RAS, Irkutsk, Russia


The models of population dynamics as tool for studying
of genetic polymorphism of Baikalian polychaets


Chumakov M.I., Mazilov S., Zotova T.V.


Institute of Symbiology RAS, Saratov, Russia

Searching for nucleotide sequences like agrobacterial T-DNA right border in plant genomes
Golovnina K.*1, Blinov A.1, Chang L.-S.2

1Institute of Cytology and Genetics SB RAS, Novosibirsk, Russia

2Center for Childhood Cancer, Children’s Research Institute, Children’s Hospital and Department of Pediatrics, The Ohio State University, USA

EVOLUTION AND ORIGIN OF NEUROFIBROMIN, THE PRODUCT


OF THE NEUROFIBROMATOSIS TYPE 1 (NF1) TUMOR-SUPRESSOR GENE
Gorbunov K.Yu.*, Lyubetsky V.A.

Institute for Information Transmission Problems of the Russian Academy of Sciences, Moscow, Russia



inferring regulatiory signal profiles and evolutionary events
Gunbin K.V., Morozov A.V., Afonnikov D.A.

Institute of Cytology and Genetics SB RAS, Novosibirsk, Russia

A METHOD FOR SEMIAUTOMATED ANALYSIS OF GENE EVOLUTION
Guryev V.1*, Smits B.M.G.1, van de Belt J. 1, Verheul M.1, Hubner N.2 , Cuppen E.1

1 Hubrecht Laboratorium, Utrecht, The Netherlands

2 Max-Delbruck-Center for Molecular Medicine (MDC), Berlin-Buch, Germany

HAPLOTYPE BLOCK STRUCTURE IS CONSERVED ACROSS MAMMALS



Kabanova A1., Novikova O1., Gunbin K1., Fet V2., Blinov A.1*

1Institute of Cytology and Genetics, SB RAS, Novosibirsk, Russia

2Marshall University, Huntington, WV, USA

Evolutionary relationships and distribution of the different
LTR retrotransposon families in plants
Khan M. 2, Jamil K.1, 2 *

1Indo American Cancer Institute and Research Centre, Hyderabad, India

2 School of Biotechnology, (MGNIRSA,) University of Mysore, Mysore, India

The Phylogenetic Analysis of Ubiquitin Conjugating Enzymes
of Cancer Metasignature
Korostishevsky M.1*, Bonne’-Tamir B.1, Bentwich Z.2, Tsimanis A.2

1Department of Human Molecular Genetics and Biochemistry, Tel Aviv University, Israel

2Institute of Clinical Immunology and AIDS, Kaplan Medical Center, Rehovot, Israel

Multi-SNP analysis of CCR5-CCR2 genes in Ethiopian Jews:
micro-evolution and HIV-resistance implications
Kovaleva G.Yu.*1,2, Gelfand M.S.1,2

1 Moscow State University, Department of Bioengeneering and Bioinformatics, Moscow, Russia

2 Institute for Information Transmission Problems RAS, Moscow, Russia

TRANSCRIPTIONAL REGULATION OF THE METHIONINE BIOSYNTHESIS


IN ACTINOBACTERIA AND STREPTOCOCCI
Kuznetsova A.Y.*1, Naumoff D.G.2

1 Moscow State University, Department of Bioengineering and Bioinformatics, Moscow, Russia

2 State Institute for Genetics and Selection of Industrial Microorganisms, Moscow, Russia

PHYLOGENETIC ANALYSIS OF COG1649, A NEW FAMILY OF PREDICTED GLYCOSYL HYDROLASES


Lashin S.A.*, Likhoshvai V.A., Kolchanov N.A, Matushkin Yu.G.

Institute of Cytology and Genetics, SB RAS, Novosibirsk, Russia



EVOLUTIONARY CONSTRUCTOR: A PACKAGE FOR MODELING COEVOLUTION
OF UNICELLULAR ORGANISMS
Lashin S.A.*, Likhoshvai V.A., Kolchanov N.A., Matushkin Yu.G.

Institute of Cytology and Genetics, SB RAS, Novosibirsk, Russia

MODELING OF HORIZONTAL GENE TRANSFER IN PROKARYOTIC POPULATIONS WITH THE “EVOLUTIONARY CONSTRUCTOR” PROGRAM PACKAGE
Liventseva V.*, Kaygorodova I.

Limnological Institute, SB RAS, Irkutsk, Russia


Molecules versus morphology in Oligochaeta systematics



Novikova O.*1, Fursov M.2, Blinov A.1

1Institute of Cytology and Genetics, SB RAS, Novosibirsk, Russia

2Novosibirsk Center of Information Technologies “UniPro”, Novosibirsk, Russia

NEW FAMILY OF LTR RETOTRANSPOSABLE ELEMENTS FROM FUNGI


Peretolchina T.E.*, Bukin Yu.S., Sitnikova T.Ya., Sherbakov D.Yu.

Limnological Institute, SB RAS, Irkutsk, Russia

POPULATION GENETIC POLYMORPHISM OF ENDEMIC MOLLUSCS
BAICALIA CARINATA (MOLLUSCA: CAENOGASTROPODA)

Rotskaya U.N., Rogozin I.B., Vasyunina E.A., Kolosova N.G., Sinitsyna O.I.*

Institute of Cytology and Genetics, SB RAS, Novosibirsk, Russia

THEORETICAL ANALYSIS OF THE MITOCHONDRIAL DNA SOMATIC MUTATION SPECTRA IN OXYS AND WISTAR RATS
Rusin L.Y.*, Lyubetsky V.A.

Institute for Information Transmission Problems RAS, Moscow, Russia



REFINEMENT OF PHYLOGENETIC SIGNAL IN MULTIPLE SEQUENCE ALIGNMENT: RESULTS OF SIMULATION STUDY


Ryabinina O.M.


Vavilov Institute of General Genetics RAS, Moscow, Russia

GENETIC DIVERSITY AND PHYLOGENETIC RELATIONSHIPS IN GROUPS
OF ASIAN GUARDIAN, SIBERIAN HUNTING AND EUROPEAN SHEPHERD DOG BREEDS



Yudin N.S.1*, Vasil’eva L.A.1, Kobzev V.F.1, Kuznetsova T.N.1, Ignatieva E.V.1,
Oshchepkov D.Yu.1, Voevoda M.I.1,2, Romaschenko A.G.1

1Institute of Cytology and Genetics, SB RAS, Novosibirsk, Russia

2Institute of Internal Medicine, SB RAMS, Novosibirsk, Russia

Association study of SNP of the TNF-alpha gene with bovine leukosis AND evaluation of its functional significance
Zotov V.S.1, Punina N.V.1, Dorokhov D.B.1, Schaad N.W.2, Ignatov A.N.1*

1Centre “Bioengineering” RAS, Moscow, Russia

2FDWSRU, USDA-ARS, MD, USA

phylogenetic changes in chloroplast genomes

4. Computational systems biology
4.1 Modeling of Molecular Genetic Systems and Processes in Bacterial Cell
Khlebodarova T.M.1, Ananko E.A.1*, Nedosekina E.A.1, Podkolodnaya O.A.1, Poplavsky A.S.1, Smirnova O.G.1, Ibragimova S.S.1, Mishchenko E.L.1, Stepanenko I.L.1, Ignatieva E.V.1, Proskura A.L.1, Nishio Y.2, Imaizumi A.2, Usuda Y.2, Matsui K.2, Podkolodny N.L.1, Kolchanov N.A.1

1Institute of Cytology and Genetics, SB RAS, Novosibirsk, Russia

2Institute of Life Sciences, Ajinomoto, Co., Inc., Kawasaki-city, Japan

IN SILICO CELL II. INFORMATION SOURCES FOR MODELING ESCHERICHIA COLI METABOLIC PATHWAYS

Ratushny A.V.1*, Usuda Y.2, Matsui K.2, Podkolodnaya O.A.1

1Institute of Cytology and Genetics, SB RAS, Novosibirsk, Russia

2Institute of Life Sciences, Ajinomoto, Co., Inc., Kawasaki, Japan

MATHEMATICAL MODELING OF ELEMENTARY PROCESSES OF THE GENE NETWORK CONTROLLING HISTIDINE BIOSYNTHESIS IN Escherichia coli


Nedosekina E.A.1*, Usuda Y.2, Matsui K.2

1Institute of Cytology and Genetics, SB RAS, Novosibirsk, Russia

2Institute of Life Sciences, Ajinomoto, Co., Inc., Kawasaki, Japan

MODELING OF THE EFFECTS OF THREONINE, VALINE, ISOLEUCINE AND PYRIDOXAL 5'-MONOPHOSPHATE ON BIOSYNTHETIC THREONINE DEHYDRATASE REACTION


Ratushny A.V.*, Nedosekina E.A.

Institute of Cytology and Genetics SB RAS, Novosibirsk, Russia

REGULATION OF PYRIMIDINE BIOSYNTHESIS IN Escherichia coli:
GENE NETWORK RECONSTRUCTION AND MATHEMATICAL MODELING
Ratushny A.V.1*, Smirnova O.G.1, Usuda Y.2, Matsui K.2

1Institute of Cytology and Genetics SB RAS, Novosibirsk, Russia

2Institute of Life Sciences, Ajinomoto, Co., Inc., Kawasaki, Japan

REGULATION OF THE PENTOSE PHOSPHATE PATHWAY IN Escherichia coli:
GENE NETWORK RECONSTRUCTION AND MATHEMATICAL MODELING
OF METABOLIC REACTIONS
Ananko E.A.1*, Ratushny A.V. 1, Usuda Y.2, Matsui K.2

1Institute of Cytology and Genetics SB RAS, Novosibirsk, Russia

2Institute of Life Sciences, Ajinomoto, Co., Inc., Kawasaki, Japan

AROMATIC AMINO ACID BIOSYNTHESIS IN Escherichia coli: GENERALIZED HILL FUNCTION MODEL OF THE TRYPTOPHAN-SENSITIVE 3-DEOXY-D-ARABINO-HEPTULOSONATE-7-PHOSPHATE SYNTHASE REACTION DEMONSTRATE COMPLICATED MECHANISM


Ratushny A.V.*, Khlebodarova T.M.

Institute of Cytology and Genetics SB RAS, Novosibirsk, Russia

MATHEMATICAL MODELING OF REGULATION OF cyоABCDE OPERON EXPRESSION
IN Escherichia coli
Khlebodarova T.M.*, Lashin S.A., Apasieva N.V.

Institute of Cytology and Genetics SB RAS, Novosibirsk, Russia



GENE NETWORK RECONSTRUCTION AND MATHEMATICAL MODELING
OF ESCHERICHIA COLI RESPIRATION: REGULATION OF F0F1-ATP SYNTHASE
BY METAL IONS
Nedosekina E.A.

Institute of Cytology and Genetics SB RAS, Novosibirsk, Russia

MATHEMATICAL MODELING OF REGULATION OF Escherichia coli PURINE BIOSYNTHESIS PATHWAY ENZYMATIC REACTIONS
Mishchenko E.L. 1*, Lashin S.A.1, Usuda Y.2, Matsui K.2

1Institute of Cytology and Genetics SB RAS, Novosibirsk, Russia

2Institute of Life Sciences, Ajinomoto, Co., Inc., Kawasaki, Japan

RECONSTRUCTION AND MATHEMATICAL MODELING OF THE GENE NETWORK CONTROLLING CYSTEINE BIOSYNTHESIS IN Escherichia coli: REGULATION


OF SERINE ACETYLTRANSFERASE ACTIVITY
Smirnova O.G.*, Ratushny A.V.

Institute of Cytology and Genetics SB RAS, Novosibirsk, Russia



GENE NETWORK RECONSTRUCTION AND MATHEMATICAL MODELING OF SALVAGE PATHWAYS: REGULATION OF ADENINE PHOSPHORIBOSYLTRANSFERASE ACTIVITY BY STRUCTURALLY SIMILAR SUBSTRATES

Turnaev I.I.1*, Ibragimova S.S.1, Usuda Y.2, Matsui K.2

1Institute of Cytology and Genetics SB RAS, Novosibirsk, Russia

2Institute of Life Sciences, Ajinomoto, Co., Inc., Kawasaki, Japan

MATHEMATICAL MODELING OF SERINE AND GLYCINE BIOSYNTHESIS REGULATION IN Escherichia coli


Turnaev I.I.*, Smirnova O.G.

Institute of Cytology and Genetics SB RAS, Novosibirsk, Russia

REGULATION OF PYRUVATE BIOSYNTHESIS IN Escherichia coli: GENE NETWORK RECONSTRUCTION AND MATHEMATICAL MODELING OF ENZYMATIC REACTIONS OF THE PATHWAY
Ibragimova S.S.*, Smirnova O.G., Grigorovich D.A., Khlebodarova T.M.

Institute of Cytology and Genetics SB RAS, Novosibirsk, Russia

BiotechPro: A DATABASE FOR MICROBIOLOGICALLY SYNTHESIZED PRODUCTS
OF BIOTECHNOLOGICAL VALUE

Peshkov I.M.1, Fadeev S.I.2


1Novosibirsk State University, Novosibirsk, Russia

2Sobolev Institute of Mathematics SB RAS, Novosibirsk, Russia

ABOUT RECONSTRUCTION OF REGULATORY MECHANISM
OF GENE ELEMENTS’ EXPRESSION

4.2 Modeling of Molecular Genetic Systems and Processes in Multicellular Organisms
Akberdin I.R.1*, Kashevarova N.A.2, Khlebodarova T.M.1, Bazhan S.I.3, Likhoshvai V.A.1

1Institute of Cytology and Genetics, SB RAS, Novosibirsk, Russia

2Novosibirsk State University, Novosibirsk, Russia

3State Research Center of Virology and Biotechnology “Vector”, Koltsovo, Russia

A MATHEMATICAL MODEL FOR THE INFLUENZA VIRUS LIFE CYCLE



Bazhan S.I.1*, Schwartz Ya.Sh.2, Gainova I.A.3, Ananko E.A.4

1State Research Center of Virology and Biotechnology “Vector”, Koltsovo, Russia

2Institute of Internal Medicine, SB RAMS, Novosibirsk

3Institute of Mathematics, SB RAS, Novosibirsk

4Institute of Cytology and Genetics, SB RAS, Novosibirsk, Russia

A MATHEMATICAL MODEL OF IMMUNE RESPONSE IN INFECTION INDUCED


BY MYCOBACTERIA TUBERCULOSIS. PREDICTION OF THE DISEASE COURSE
AND OUTCOMES AT DIFFERENT TREATMENT REGIMENS
Bezmaternikh K.D., Mishchenko E.L.*, Ratushny A.V., Likhoshvai V.A., Khlebodarova T.M., Ivanisenko V.A.

Institute of Cytology and Genetics SB RAS, Novosibirsk, Russia

A MINIMUM MATHEMATICAL MODEL FOR SUPPRESSION HCV RNA REPLICATION
IN CELL CULTURE
Fadeev S.I.1*, Shtokalo D.N.2, Likhosvai V.A.3

1Sobolev Institute of Mathematics SB RAS, Novosibirsk, Russia

2Novosibirsk State University, Novosibirsk, Russia

3Institute of Cytology and Genetics SB RAS, Novosibirsk, Russia

MATRIX PROCESS MODELLING: STUDY OF A MODEL OF SYNTHESIS
OF LINEAR BIOMOLECULES WITH REGARD TO REVERSIBILITY OF PROCESSES
Gursky V.V.1*, Samsonov A.M.1, Reinitz J.2

1Ioffe Physico-Technical Institute of the Russian Academy of Sciences, St. Petersburg, Russia

2Stony Brook University, Stony Brook, New York, USA

APPROXIMATE STATIONARY ATTRACTORS IN DROSOPHILA GAP GENE CIRCUITS


IN THE LIMIT OF STEEP-SIGMOID INTERACTIONs
Kalashnikova E.V.1, Dymshits G. M.1, Kolpakov F.A.2,3

1Institute of Cytology and Genetics SB RAS, Novosibirsk, Russia

2Design Technological Institute of Digital Techniques SB RAS, Novosibirsk, Russia
3Institute of Systems Biology OOO, Novosibirsk, Russia

SIGNAL TRANSDUCTION PATHWAYS INVOLVED IN TRANSCRIPTIONAL REGULATION OF TYROSINE HYDROXYLASE


Mischenko E.L.1, Korotkov R.O.2, Ivanisenko V.A.1,2*

1Institute of Cytology and Genetics SB RAS, Novosibirsk, Russia

2Novosibirsk State University, Novosibirsk, Russia

HCV-KINET DATABASE: KINETIC PARAMETER REACTIONS AND REGULATORY PROCESSES OF THE LIFE CYCLE OF THE HEPATITIS C VIRUS


Ratushny A.V.

Institute of Cytology and Genetics SB RAS, Novosibirsk, Russia



MATHEMATICAL MODELING OF RECEPTOR MEDIATED ENDOCYTOSIS
OF LOW-DENSITY LIPOPROTEINS AND THEIR DEGRADATION IN LYSOSOMES
Ratushny A.V.

Institute of Cytology and Genetics SB RAS, Novosibirsk, Russia



MATHEMATICAL MODELING OF THE GENE NETWORK CONTROLLING HOMEOSTASIS OF INTRACELLULAR CHOLESTEROL
Ratushny A.V.*, Bezmaternikh K.D

Institute of Cytology and Genetics SB RAS, Novosibirsk, Russia

CONSERVED PROPERTIES OF ENZYMATIC SYSTEMS: PRENYLTRANSFERASE KINETICS
Sharipov R.N.1,2,3,*, Kolpakova A.F.4

1Institute of Cytology and Genetics, SB RAS, Novosibirsk, Russia

2Design Technological Institute of Digital Techniques SB RAS, Novosibirsk, Russia

3Institute of Systems Biology OOO, Novosibirsk, Russia

4State Research Institute for Medical Problems of the North, SB RAMS, Krasnoyarsk, Russia

Formal description of NF-B pathway, its role in inflammation, inhibition of apoptosis, carcinogenesis, and ways of inactivation
for prediction of new targets for anti-inflammatory and anti-cancer treatment
Stepanenko I.L1*., Podkolodnaya N.N.1, Paramonova N.V.1, Podkolodny N.L.1,2

1Institute of Cytology and Genetics, SB RAS, Novosibirsk, Russia

2Institute of Computational Mathematics and Mathematical Geophysics SB RAS,
Novosibirsk, Russia

RECONSTRUCTION AND STRUCTURE ANALYSIS OF APOPTOSIS GENE NETWORK


IN HEPATITIS C

4.3 Modeling of morphogenesis
Bukharina T.A.1, Katokhin A.V.1,2, Furman D.P.1,2

1Institute of Cytology and Genetics, SB RAS, Novosibirsk, Russia

2Novosibirsk State University, Novosibirsk, Russia

THE GENE NETWORK DETERMINING DEVELOPMENT OF DROSOPHILA MELANOGASTER MECHANORECEPTORS

Mironova V.V.1*, Poplavsky A.S.1, Ponomarev D.K.2, Omelianchuk N.A.1


1Institute of Cytology and Genetics, SB RAS, Novosibirsk, Russia

2Institute of Informatics System,

tait SB RAS, Novosibirsk, Russia

ONTOLOGY OF ARABIDOPSIS GENE NET SUPPLEMENTARY DATABASE (AGNS), CROSS DATABASE REFERENCES TO TAIR ONTOLOGY
Nikolaev S.V.1*, Fadeev S.I.2, Kogay V.V.2, Mjolsness E.3, Kolchanov N.A.1

1Institute of Cytology and Genetics, SB RAS, Novosibirsk, Russia

2Institute of Mathematics SB RAS, Novosibirsk, Russia

3School of Information and Computer Science, and Institute for Genomics and Bioinformatics, University of California, Irvine, USA

A one-dimensional model for the regulation of the size
of the renewable zone in biological tissue
Nikolaev S.V.1*, Penenko A.V.2, Belavskaya V.V.1, Mjolsness E.3, Kolchanov N.A.1

1Institute of Cytology and Genetics, SB RAS, Novosibirsk, Russia

2Institute of Mathematics, SB RAS, Novosibirsk, Russia

3School of Information and Computer Science, and Institute for Genomics and Bioinformatics, University of California, Irvine, USA

A SYSTEM FOR SIMULATION OF 2D PLANT TISSUE GROWTH AND DEVELOPMENT


Ponomaryov D.1*, Omelianchuk N.2, Kolchanov N.2, Mjolsness E.3, Meyerowitz E.4

1 Institute of Informatics Systems, SB RAS, Novosibirsk, Russia

2 Institute of Cytology and Genetics, SB RAS, Novosibirsk, Russia

3 Institute for Genomics and Bioinformatics, University of California, Irvine, USA

4 Division of Biology, California Institute of Technology, Pasadena, CA, USA

Semantically rich ontology of anatomical structure
and development for Arabidopsis thaliana L.




4.4 Gene networks theory: mathematical problems and software
Aman E.E.*, Levitsky V.G., Ignatieva E.V.

Institute of Cytology and Genetics, SB RAS, Novosibirsk, Russia

RECONSTRUCTION AND COMPUTER ANALYSIS OF THE GENE NETWORK
OF FATTY ACID -OXIDATION REGULATED BY THE PPAR TRANSCRIPTIONAL FACTORS
Demidenko G.V.1*, Khropova Yu.E.2

1Sobolev Institute of Mathematics, SB RAS, Novosibirsk, Russia

2Novosibirsk State University, Novosibirsk, Russia

MATRIX PROCESS MODELLING: ON PROPERTIES OF SOLUTIONS


OF ONE DELAY DIFFERENTIAL EQUATIONS
Demidenko G.V.1*, Khropova Yu.E.2, Kotova T.V.2

1Sobolev Institute of Mathematics, SB RAS, Novosibirsk, Russia

2Novosibirsk State University, Novosibirsk, Russia

MATRIX PROCESS MODELLING: ON ONE CLASS OF INFINITE-ORDER SYSTEMS


OF DIFFERENTIAL EQUATIONS AND ON DELAY DIFFERENTIAL EQUATIONS
Demidenko G.V.1*, Mudrov A.V. 2

1Sobolev Institute of Mathematics, SB RAS, Novosibirsk, Russia

2Novosibirsk State University, Novosibirsk, Russia

MATRIX PROCESS MODELLING: ON A NEW METHOD OF APPROXIMATION


OF SOLUTIONS OF DELAY DIFFERENTIAL EQUATIONS
Fadeev S.I.*, Korolev V.K.

Sobolev Institute of Mathematics, SB RAS, Novosibirsk, Russia

PROGRAM PACKAGE HGNET FOR COMPUTATIONAL INVESTIGATION
OF HYPOTHETICAL GENE NETWORKS
Klishevich M.A.*, Kogai V.V., Fadeev S.I.

Sobolev Institute of Mathematics, SB RAS, Novosibirsk, Russia



RESEARCH OF CYCLIC GENE NETWORK CIRCUITS WITH NEGATIVE TYPE
OF REGULATION
Kolpakov F.1,2*, Sharipov R.3,1,2, Cheremushkina E.2, Kalashnikova E.3

1Institute of Systems Biology OOO, Novosibirsk, Russia

2Design Technological Institute of Digital Techniques, SB RAS, Novosibirsk, Russia

3Institute of Cytology and Genetics, SB RAS, Novosibirsk, Russia

Biopath – a new approach to formalized description and simulation
of biological systems

Komarov A.V.1*, Akberdin I. R.2, Ozonov E. A.1, Evdokimov A. A.3


1Novosibirsk State University, Novosibirsk, Russia

2Institute of Cytology and Genetics, SB RAS, Novosibirsk, Russia

3Sobolev Institute of Mathematics, SB RAS, Novosibirsk, Russia

ON THE RECONSTRUCTION OF GENETIC AUTOMATE ON THE BASIS


OF BOOLEAN DYNAMIC DATA

Likhoshvai V.A.1*, Rudneva D.S.2, Fadeev S.I.3

1Institute of Cytology and Genetics, SB RAS, Novosibirsk, Russia

2Novosibirsk State University, Novosibirsk, Russia

3Sobolev Institute of Mathematics, SB RAS, Novosibirsk, Russia

OSCILLATIONS OF CHAOTIC TYPE IN SYMMETRIC GENE NETWORKS
OF SMALL DIMENSION
Matveeva I.I. 1, Popov A.M.

1Sobolev Institute of Mathematics, SB RAS, Novosibirsk, Russia

2Novosibirsk State University, Novosibirsk, Russia

matrix process modelling: Dependence of solutions
of a system of DIFferential equations on parameter
Podkolodny N.L.1,2*, Podkolodnaya N.N.1, Miginsky D.S.1, Poplavsky A.S.1, Likhoshvai V.A.1, Compani B.3, Mjolsness E.3

1Institute of Cytology and Genetics, SB RAS, Novosibirsk, Russia

2Institute of Computational Mathematics and Mathematical Geophysics, SB RAS,
Novosibirsk, Russia

3Institute for Genomics and Bioinformatics, University of California, Irvine, USA

AN INTEGRATION OF THE DESCRIPTIONS OF gene networkS AND THEIR MODELS PRESENTED IN SIGMOID (cELLERATOR) and GENENET
Tchuraev R.N.

Department of Physicochemical Biology and Epigenetics, Ufa Research Center, RAS, Ufa, Russia


RESEARCH ON BEHAVIOR OF GOVERNING GENE/EPIGENE NETWORKS
AS A PROBLEM OF CELLULAR AUTOMATA IDENTIFICATION

5. NEW APPROACHES TO ANALYSIS/MODELING OF BIOMOLECULAR DATA
AND PROCESSES
Arrigo P.1*, Cardo P.P.2

1CNR Institute for Macromolecular Studies, Genoa, Italy

2Department of Health Science, University of Genoa, Genoa, Italy

Investigation of Named entity recognition in molecular biology
by data fusion
Axenovich M.A.

Department of Mathematics, Iowa State University, Ames, USA



Edit distance in combinatorial structures
Axenovich T.I.

Institute of Cytology and Genetics, SB RAS, Novosibirsk, Russia



Graph theory algorithm for solution of computational problems
of gene mapping
Huang Shaoqing *, Cui Yini

College of Life Science and Biotechnology, Shanghai Jiao Tong University, Shanghai, China

UNEQUALLY SPACED SAMPLING MAPPING OF QTL
Kolpakov F.1,2,*, Poroikov V.3, Sharipov R.4,2,1, Milanesi L.5, Kel A.6

1Design Technological Institute of Digital Techniques, SB RAS, Novosibirsk, Russia

2Institute of Systems Biology, Novosibirsk OOO, Russia

3Institute of Biomedical Chemistry, RAMS, Moscow, Russia

4Institute of Cytology and Genetics, SB RAS, Novosibirsk, Russia

5Institute of Biomedical Technologies, Segrate (MI), Italy

6BIOBASE GmbH, Wolfenbuettel, Germany

Cyclonet — an integrated database on cell cycle regulation
and carcinogenesis
Miginsky D.S.1,3*, Sokolov S.A.2, Labuzhsky V.V.2, Nikitin A.G.2,3

1 Institute of Cytology and Genetics, SB RAS, Novosibirsk, Russia

2A.P. Ershov Institute of Informatics Systems SB RAS

3Novosibirsk State University, Novosibirsk, Russia

Object-oriented approach to bioinformatics software resources integration
Sarsenbaev K.N.

Institute of Radiation Safety and Ecology, Kurchatov, Kazakhstan



Use molecular markers for differentiation populations of Stipa capillata growing in the regions with high chronical doses
of -radiation
Suslov V.V1*, Sergeev M.G.2, Yurlova N.I.3, Miginsky D.S.1,2

1Institute of Cytology and Genetics, SB RAS, Novosibirsk, Russia

2Novosibirsk State University, Novosibirsk, Russia

3Institute of Animal Systematics and Ecology, SB RAS, Novosibirsk, Russia

THE ONTOLOGY OF ECOSYSTEMS




COMPUTER DEMONSTRATIONS (by sections)
Computer demos will be available during the entire conference day
for the appropriate sections
Munday, July 17
COMPUTATIONAL STRUCTURAL AND FUNCTIONAL GENOMICS
and transcriptomics
Vishnevsky O.V.1,2*, Konstantinov Yu.M.3

1Institute of Cytology and Genetics SB RAS, Novosibirsk, Russia

2Novosibirsk State University, Novosibirsk, Russia

3Siberian Institute of Plant Physiology and Biochemistry SB RAS, Irkutsk, Russia

ANALYSIS OF THE NUCLEOTIDE CONTEXT OF HIGHER PLANT MITOCHONDRIAL mRNA EDITING SITES

Thursday, July 20
Comparative and evolutionary genomics AND PROTEOMICS
Chupov V.S.*, Machs E.M.

Komarov Botanical institute RAS, St.Petersburg, Russia



Variations in nucleotide composition of the region ITS1-5.8S rDNA-ITS2
in evolutionary advanced and evolutionary static branch
of the Monocotyledonous plants
NEW APPROACHES TO ANALYSIS/MODELING OF BIOMOLECULAR DATA AND PROCESSES

Kolpakov F.1,2,*, Poroikov V.3, Sharipov R.4,2,1, Milanesi L.5, Kel A.6

1Design Technological Institute of Digital Techniques, SB RAS, Novosibirsk, Russia

2Institute of Systems Biology, Novosibirsk OOO, Russia

3Institute of Biomedical Chemistry, RAMS, Moscow, Russia

4Institute of Cytology and Genetics, SB RAS, Novosibirsk, Russia

5Institute of Biomedical Technologies, Segrate (MI), Italy

6BIOBASE GmbH, Wolfenbuettel, Germany

Cyclonet — an integrated database on cell cycle regulation
and carcinogenesis
Kolpakov F.1,2*, Puzanov M.1,2, Koshukov A.1,2

1Institute of Systems Biology OOO, Novosibirsk, Russia

2Design Technological Institute of Digital Techniques SB RAS, Novosibirsk, Russia

BioUML: visual modeling, automated code generation and simulation


of biological systems

Friday, July 21

Saturday, July 22
Computational systems biology
Fadeev S.I.1*, Korolev V.K.1, Gainova I.A.2, Medvedev3A.E.

1Sobolev Institute of Mathematics SB RAS, Novosibirsk, Russia

2Khristianovich Institute of Theoretical and Applied Mechanics SB RAS, Novosibirsk, Russia

3Institute of Cytology and Genetics SB RAS, Novosibirsk, Russia

THE PACKAGE STEP+ FOR NUMERICAL STUDY OF AUTONOMOUS SYSTEMS ARISING WHEN MODELING DYNAMICS OF GENETIC-MOLECULAR SYSTEMS


Kolpakov F.1,2*, Sharipov R.3,1,2, Cheremushkina E.2, Kalashnikova E.3

1Institute of Systems Biology OOO, Novosibirsk, Russia

2Design Technological Institute of Digital Techniques, SB RAS, Novosibirsk, Russia

3Institute of Cytology and Genetics, SB RAS, Novosibirsk, Russia

Biopath – a new approach to formalized description and simulation
of biological systems
Rudenko V.M.*, Korotkov E.V.

Center of Bioengineering RAS, Moscow, Russia



construction of the HCV-HEPATOCYTE SYSTEM MODEL
Sharipov R.N.1,2,3*, Kolpakova A.F.4

1Institute of Cytology and Genetics, SB RAS, Novosibirsk, Russia

2Design Technological Institute of Digital Techniques SB RAS, Novosibirsk, Russia

3Institute of Systems Biology OOO, Novosibirsk, Russia

4State Research Institute for Medical Problems of the North, SB RAMS, Krasnoyarsk, Russia

Formalized description of NF-B pathway, its role in inflammation, inhibition of apoptosis, carcinogenesis, and ways of inactivation
for prediction of new targets for anti-inflammatory
and anti-cancer treatment

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