Personal Research Database Bibliometric

Full Text: 2014\Wor J Gas20, 829.pdf

Abstract: AIM: To review the effectiveness of distance management methods in the management of adult inflammatory bowel disease (IBD) patients. METHODS: A systematic review and meta-analysis of randomized controlled trials comparing distance management and standard clinic follow-up in the management of adult IBD patients. Distance management intervention was defined as any remote management method in which there is a patient self-management component whereby the patient interacts remotely via a self-guided management program, electronic interface, or self-directs open access to clinic follow up. The search strategy included electronic databases (Medline, PubMed, CINAHL, the Cochrane Central Register of Controlled Trials, EMBASE, KTPlus, Web of Science, and SCOPUS), conference proceedings, and internet search for web publications. The primary outcome was the mean difference in quality of life, and the secondary outcomes included mean difference in relapse rate, clinic visit rate, and hospital admission rate. Study selection, data extraction, and risk of bias assessment were completed by two independent reviewers. RESULTS: the search strategy identified a total of 4061 articles, but only 6 randomized controlled trials met the inclusion and exclusion criteria for the systematic review and meta-analysis. Three trials involved telemanagement, and three trials involved directed patient self-management and open access clinics. The total sample size was 1463 patients. There was a trend towards improved quality of life in distance management patients with an end IBDQ quality of life score being 7.28 (95% CI: -3.25-17.81) points higher than standard clinic follow-up. There was a significant decrease in the clinic visit rate among distance management patients mean difference -1.08 (95% CI: -1.60--0.55), but no significant change in relapse rate or hospital admission rate. CONCLUSION: Distance management of IBD significantly decreases clinic visit utilization, but does not significantly affect relapse rates or hospital admission rates. (C) 2014 Baishideng Publishing Group Co., Limited. All rights reserved.

Keywords: Access, Adult, Assessment, Bias, Bowel, Clinic, Co, Colitis Uc Hat, Conference Proceedings, Criteria, Crohns-Disease, Data, Databases, Disease, Distance Management, Effectiveness, Embase, Extraction, Follow-Up, Guided Self-Management, Health-Care Utilization, Home Telemanagement, Hospital, Inflammatory Bowel Disease, Interface, Intervention, Life, Management, Medline, Meta Analysis, Meta-Analysis, Metaanalysis, Methods, Open, Open Access, Outcome, Outcomes, Patient Education, Patients, Primary, Publications, Publishing, Pubmed, Quality, Quality Of, Quality of Life, Quality-Of-Life, Randomized, Randomized Controlled Trials, Randomized Controlled-Trial, Rates, Relapse, Relapse Rate, Review, Rights, Risk, Sample Size, Science, Scopus, Search Strategy, Selection, Self Management, Self-Management, Size, Standard, Strategy, Systematic Review, Telehealth, Telemanagement, Trend, Ulcerative-Colitis, Utilization, Wait Times Program, Web, Web of Science

? Lin, S., Ma, R., Zheng, X.Y., Yu, H., Liang, X., Lin, H. and Cai, X.J. (2014), Meta-analysis of immunohistochemical expression of hypoxia inducible factor-1 as a prognostic role in gastric cancer. World Journal of Gastroenterology, 20 (4), 1107-1113.

Full Text: 2014\Wor J Gas20, 1107.pdf

Abstract: AIM: To conduct a meta-analysis to evaluate the prognostic role of hypoxia inducible factor-1 alpha (HIF-1 alpha) expression in gastric cancer. METHODS: the PubMed, EMBASE, and Web of Science databases were searched systematically for all articles published in English before August, 2013. Pooled effect was calculated from the available data to evaluate the association between HIF-1 alpha expression and 5-year overall survival and tumor clinicopathological features in gastric cancer patients. Pooled odds ratios (ORs) with 95% CIs were calculated using either a fixed-effects or a random-effects model. RESULTS: Nine studies matched the selection criteria, which reported on 1103 subjects, 548 of whom had HIF-1 alpha positive expression (50%). This meta-analysis indicated that HIF-1 alpha positive expression in gastric cancer correlated with lower 5-year overall survival (OR = 0.36; 95% CI: 0.21-0.64), worse tumor differentiation (OR = 0.38; 95% CI: 0.23-0.64), deeper invasion (OR = 0.42; 95% CI: 0.32-0.57), higher rates of lymph node metastasis (OR = 2.23; 95% CI: 1.46-3.40), lymphatic invasion (OR = 2.50; 95% CI: 1.46-4.28), and vascular invasion (OR = 1.80; 95% CI: 1.29-2.51), and higher TNM stage (III + IV) (OR = 0.31; 95% CI: 0.15-0.60). CONCLUSION: HIF-1 alpha positive expression indicates a poor prognosis for patients with gastric cancer. Further studies are required to confirm these results. (C) 2014 Baishideng Publishing Group Co., Limited. All rights reserved.

Keywords: 5-Year Overall Survival, Adenocarcinoma, Angiogenesis, Association, Cancer, Carcinoma, Clinicopathological Features, Clinicopathological Significance, Co, Criteria, Data, Databases, Differentiation, Embase, Expression, Gastric, Gastric Cancer, Growth, Hif-1-Alpha, Hypoxia, Hypoxia Inducible Factor-1 Alpha, Impact, Iv, Meta Analysis, Meta-Analysis, Metaanalysis, Metastasis, Methods, Model, Overexpression, Patients, Prognosis, Prognostic, Publishing, Pubmed, Random Effects Model, Rates, Rights, Role, Science, Selection, Selection Criteria, Survival, Tumor, VEGF, Web of Science, Web of Science Databases

? Chao, G.Q. and Zhang, S. (2014), Effectiveness of acupuncture to treat irritable bowel syndrome: A meta-analysis. World Journal of Gastroenterology, 20 (7), 1871-1877.

Full Text: 2014\Wor J Gas20, 1871.pdf

Abstract: AIM: To evaluate the efficacy of acupuncture for treatment of irritable bowel syndrome (IBS) through meta-analysis of randomized controlled trials. METHODS: We searched MEDLIINE, PubMed, Scopus, Web of Science, and Cochrane Central Register of Controlled Trials from 1966 to February 2013 for doubleblind, placebo-controlled trials investigating the efficacy of acupuncture in the management of IBS. Studies were screened for inclusion based on randomization, controls, and measurable outcomes reported. We used the modified Jadad score for assessing the quality of the articles. STATA 11.0 and Revman 5.0 were used for meta-analysis. Publication bias was assessed by Begg’s and Egger’s tests. RESULTS: Six randomized, placebo-controlled clinical trials met the criteria and were included in the metaanalysis. The modified Jadad score of the articles was > 3, and five articles were of high quality. We analyzed the heterogeneity and found that these studies did not cause heterogeneity in our meta-analysis. Begg’s test showed P = 0.707 and Egger’s test showed P = 0.334. There was no publication bias in our meta-analysis (Begg’s test, P = 0.707; Egger’s test, P = 0.334). From the forest plot, the diamond was on the right side of the vertical line and did not intersect with the line. The pooled relative risk for clinical improvement with acupuncture was 1.75 (95% CI: 1.24-2.46, P = 0.001). Using the two different systems of STATA 11.0 and Revman 5.0, we confirmed the significant efficacy of acupuncture for treating IBS. CONCLUSION: Acupuncture exhibits clinically and statistically significant control of IBS symptoms. (C) 2014 Baishideng Publishing Group Co., Limited. All rights reserved.

Keywords: Acupuncture, Assessing, Bias, Bowel, Clinical, Clinical Trials, Co, Control, Criteria, Diamond, Efficacy, Forest, Functional Gastrointestinal Disorder, Functional Gastrointestinal Disorders, Heterogeneity, Hypersensitivity, Ib, Impact, Improvement, Irritable Bowel Syndrome, Management, Meta Analysis, Meta-Analysis, Metaanalysis, Methods, Modified, Outcomes, P, Primary-Care, Publication, Publication Bias, Publishing, Pubmed, Quality, Quality Of, Randomization, Randomized, Randomized Controlled Trials, Randomized-Controlled-Trial, Relative Risk, Right, Rights, Risk, Science, Scopus, Symptoms, Syndrome, Systems, Treatment, Vertical, Web of Science

? Ji, X.Q., Du, J.F., Chen, G., Chen, G. and Yu, B. (2014), Efficacy of ilaprazole in the treatment of duodenal ulcers: A meta-analysis. World Journal of Gastroenterology, 20 (17), 5119-5123.

Full Text: 2014\Wor J Gas20, 5119.pdf

Abstract: AIM: To compare the efficacy and tolerance of ilaprazole compared with other proton pump inhibitors (PPIs) in the treatment of duodenal ulcer. METHODS: An electronic database search of Medline, Embase, the Cochrane controlled trials register, Web of Science, PubMed, and the Chinese Biomedical Literature Database (updated to July 2013), and manual searches were conducted. A meta-analysis of randomized controlled trials comparing the efficacy and tolerance of ilaprazole and other PPIs in the treatment of duodenal ulcers was performed. RESULTS: Five articles involving 1481 patients were included. The meta-analysis showed no difference in the 4-wk healing rate between ilaprazole and other PPIs [89.7% vs 87.0%; relative risk (RR) = 1.02; 95%CI: 0.98-1.06; Z = 1.00; P = 0.32]. The results did not change in the sensitivity analyses. The meta-analysis indicated that the adverse effect rate in the ilaprazole group was lower than that in the control group, but the difference was not significant (9.7% vs 13.0%; RR = 0.81; 95%CI: 0.60-1.07; Z = 1.47; P = 0.14). CONCLUSION: Ilaprazole is a highly effective and safe PPI in the treatment of duodenal ulcers. Ilaprazole can be recommended as a therapy for acid-related disorders, especially in Asian populations. (C) 2014 Baishideng Publishing Group Co., Limited. All rights reserved.

Keywords: Analyses, Articles, Asian, Biomedical, Chinese, Co, Control, Database, Disease, Double-Blind, Duodenal Ulcer, Efficacy, Healing, Ilaprazole, Inhibitors, Iy-81149, Literature, Management, Medline, Meta Analysis, Meta-Analysis, Metaanalysis, Methods, Omeprazole, P, Patients, Peptic-Ulcer, Pharmacology, Populations, Proton Pump Inhibitor, Proton Pump Inhibitor, Publishing, PubMed, Pump, Quality, Randomized, Randomized Controlled Trials, Randomized-Trials, Relative Risk, Rights, Risk, Science, Sensitivity, Therapy, Tolerance, Treatment, Web of Science

? Guo, H.M., Zhang, X.Q., Chen, M., Huang, S.L. and Zou, X.P. (2014), Endoscopic submucosal dissection vs endoscopic mucosal resection for superficial esophageal cancer. World Journal of Gastroenterology, 20 (18), 5540-5547.

Full Text: 2014\Wor J Gas20, 5540.pdf

Abstract: AIM: To investigate the effectiveness of endoscopic submucosal dissection (ESD) and endoscopic mucosal resection (EMR) in treating superficial esophageal cancer (SEC). METHODS: Studies investigating the safety and efficacy of ESD and EMR for SEC were searched from the databases of Pubmed, Web of Science, EMBASE and the Cochrane Library. Primary end points included the en bloc resection rate and the curative resection rate. Secondary end points included operative time, rates of perforation, postoperative esophageal stricture, bleeding and local recurrence. The random-effect model and the fixed-effect model were used for statistical analysis. RESULTS: Eight studies were identified and included in the meta-analysis. As shown by the pooled analysis, ESD had significantly higher en bloc and curative resection rates than EMR. Local recurrence rate in the ESD group was remarkably lower than that in the EMR group. However, operative time and perforation rate for ESD were significantly higher than those for EMR. As for the rate of postoperative esophageal stricture and procedure-related bleeding, no significant difference was found between the two techniques. CONCLUSION: ESD seems superior to EMR in the treatment of SEC as evidenced by significantly higher en bloc and curative resection rates and by obviously lower local recurrence rate. (C) 2014 Baishideng Publishing Group Co., Limited. All rights reserved.

Keywords: Advantages, Analysis, Bleeding, Cancer, Co, Databases, Dissection, Early Gastric-Cancer, Effectiveness, Efficacy, Embase, Emr, Endoscopic, Endoscopic Mucosal Resection, Endoscopic Submucosal Dissection, Esophageal Cancer, Local, Meta Analysis, Meta-Analysis, Metaanalysis, Methods, Model, Mucosal, Operative, Operative Time, Postoperative, Publishing, Rates, Recurrence, Rights, Safety, Science, Statistical Analysis, Superficial Esophageal Cancer, Techniques, Treatment, Tumors, Web Of Science

? Kong, Y.J., Yi, H.G., Dai, J.C. and Wei, M.X. (2014), Histological changes of gastric mucosa after Helicobacter pylori eradication: A systematic review and meta-analysis. World Journal of Gastroenterology, 20 (19), 5903-5911.

Full Text: 2014\Wor J Gas20, 5903.pdf

Abstract: AIM: To systematically review pathological changes of gastric mucosa in gastric atrophy (GA) and intestinal metaplasia (IM) after Helicobacter pylori (H. pylori) eradication. METHODS: A systematic search was made of PubMed, Web of Science, EMBASE, ClinicalTrials.gov, OVID and the Cochran Library databases for articles published before March 2013 pertaining to H. pylori and gastric premalignant lesions. Relevant outcomes from articles included in the meta-analysis were combined using Review Manager 5.2 software. A Begg’s test was applied to test for publication bias using STATA 11 software. chi(2) and I-2 analyses were used to assess heterogeneity. Analysis of data with no heterogeneity (P > 0.1, I-2 < 25%) was carried out with a fixed effects model, otherwise the causes of heterogeneity were first analyzed and then a random effects model was applied. RESULTS: The results of the meta-analysis showed that the pooled weighted mean difference (WMD) with 95% CI was 0.23 (0.18-0.29) between eradication and non-eradication of H. pylori infection in antral IM with a significant overall effect (Z = 8.19; P < 0.00001) and no significant heterogeneity (chi(2) = 27.54, I-2 = 16%). The pooled WMD with 95%CI was -0.01 (-0.04-0.02) for IM in the corpus with no overall effect (Z = 0.66) or heterogeneity (chi(2) = 14.87, I-2 = 0%) ( fixed effects model). In antral GA, the pooled WMD with 95% CI was 0.25 (0.15-0.35) with a significant overall effect (Z = 4.78; P < 0.00001) and significant heterogeneity (chi(2) = 86.12, I-2 = 71%; P < 0.00001). The pooled WMD with 95% CI for GA of the corpus was 0.14 (0.04-0.24) with a significant overall effect (Z = 2.67; P = 0.008) and significant heterogeneity (chi(2) = 44.79, I-2 = 62%; P = 0.0003) (random effects model). CONCLUSION: H. pylori eradication strongly correlates with improvement in IM in the antrum and GA in the corpus and antrum of the stomach. (C) 2014 Baishideng Publishing Group Inc. All rights reserved.

Keywords: Analyses, Analysis, Articles, Atrophic Body Gastritis, Atrophy, Bias, Cancer-Epidemiology, Changes, Correlates, Cure, Data, Databases, Effects, Embase, Endoscopic Resection, First, Fixed Effects Model, Gastric, Gastric Atrophy, Gastric Mucosa, Helicobacter Pylori, Helicobacter Pylori Eradication, Heterogeneity, Improvement, Infection, Intestinal Metaplasia, Intestinal Metaplasia, Meta Analysis, Meta-Analysis, Metaanalysis, Methods, Model, Outcomes, P, Pathological Changes, Publication, Publication Bias, Publishing, Pubmed, Random Effects Model, Randomized Controlled-Trial, Review, Rights, Science, Software, Sydney System, Systematic, Systematic Review, Term-Follow-Up, Therapy, Web Of Science

? Cui, P.J., Yao, J., Han, H.Z., Zhao, Y.J. and Yang, J. (2014), Does hyoscine butylbromide really improve polyp detection during colonoscopy? A meta-analysis of randomized controlled trials. World Journal of Gastroenterology, 20 (22), 7034-7039.

Full Text: 2014\Wor J Gas20, 7034.pdf

Abstract: AIM: To investigate the benefits of hyoscine butylbromide in polyp detection during colonoscopy by a meta-analysis of available randomized controlled trials (RCTs). METHODS: Databases, including PubMed, EMBASE, the Cochrane Library, and the Science Citation Index up to September 2013, were searched. The primary outcome was polyp detection rate, and the secondary outcome was adenoma detection rate. The meta-analysis was performed using the free software Review Manager. Differences observed between the treated and the control groups were expressed as odds ratio (OR) with a 95% confidence interval (CI). A fixed-effects model was used to pool data when statistical heterogeneity was absent. If statistical heterogeneity was present (P < 0.05), a random-effects model was used. RESULTS: The initial search identified nine articles. After screening, five RCTs with a total of 1998 patients were included in this meta-analysis. Of the five studies, all described a comparison of baseline patient characteristics and showed that there was no statistically significant difference between the two groups. Among the 1998 patients, 1006 received hyoscine butylbromide and 992 were allocated to the control group, and the polyp detection rate was reported. There were no significant differences between the treated and the control group (OR = 1.09, 95%CI: 0.91-1.31, P = 0.33). Four RCTs included 1882 patients, of whom 948 received hyoscine butylbromide, and the adenoma detection rate was reported. There were no significant differences between the treated and the control group (OR = 1.13, 95%CI: 0.92-1.38, P = 0.24). CONCLUSION: The use of hyoscine butylbromide did not significantly improve the polyp detection rate during colonoscopy. (C) 2014 Baishideng Publishing Group Inc. All rights reserved.

Keywords: Adenoma, Adenoma Detection, Adenoma Miss Rates, Articles, Benefit, Benefits, Characteristics, Citation, Colonoscopy, Colorectal-Cancer, Comparison, Confidence, Control, Control Groups, Data, Databases, Differences, Double-Blind, Embase, Fixed Effects Model, Groups, Heterogeneity, Hyoscine Butylbromide, Interval, Meta Analysis, Meta-Analysis, Metaanalysis, Methods, Model, N-Butyl Bromide, Odds Ratio, Outcome, P, Patients, Placebo-Controlled Trial, Polyp Detection, Premedication, Primary, Publishing, Pubmed, Quality, Random Effects Model, Randomized, Randomized Controlled Trials, Review, Rights, Science, Science Citation Index, Screening, Software, Tandem Colonoscopy, Withdrawal

? Shi, Q.Q., Ning, X.Y., Zhan, L.L., Tang, G.D. and Lv, X.P. (2014), Placement of prophylactic pancreatic stents to prevent post-endoscopic retrograde cholangiopancreatography pancreatitis in high-risk patients: A meta-analysis. World Journal of Gastroenterology, 20 (22), 7040-7048.

Full Text: 2014\Wor J Gas20, 7040.pdf

Abstract: AIM: To assess the effectiveness of pancreatic stents for preventing pancreatitis in high-risk patients after endoscopic retrograde cholangiopancreatography (ERCP). METHODS: PubMed, Embase, Science Citation Index, and Cochrane Controlled Trials Register were searched to identify relevant trials published in English. Inclusion and exclusion criteria were used to screen for suitable studies. Two reviewers independently judged the study eligibility while screening the citations. The methodological quality of the included trials was assessed using the Jadad scoring system. All results were expressed as OR and 95%CI. Data were analyzed using Stata12.0 software. RESULTS: Ten eligible randomized controlled trials were selected, including 1176 patients. A fixed-effects model in meta-analysis supported that pancreatic duct stents significantly decreased the incidence of post-ERCP pancreatitis (PEP) in high-risk patients (OR = 0.25; 95%CI: 0.17-0.38; P < 0.001). Pancreatic stents also alleviated the severity of PEP (mild pancreatitis after ERCP: OR = 0.33; 95%CI: 0.21-0.54; P < 0.001; moderate pancreatitis after ERCP: OR = 0.30; 95%CI: 0.13-0.67; P = 0.004). The result of severe pancreatitis after ERCP was handled more rigorously (OR = 0.24; 95%CI: 0.05-1.16; P = 0.077). Serum amylase levels were not different between patients with pancreatic stents and control patients (OR = 1.08; 95%CI: 0.82-1.41; P = 0.586). CONCLUSION: Placement of prophylactic pancreatic stents may lower the incidence of post-ERCP pancreatitis in high-risk patients and alleviate the severity of this condition. (C) 2014 Baishideng Publishing Group Inc. All rights reserved.

Keywords: Biliary Sphincterotomy, Cannulation, Citation, Citations, Complications, Control, Criteria, Data, Duct Stents, Effectiveness, Endoscopic Retrograde Cholangiopancreatography, English, ERCP, ERCP Pancreatitis, Fixed Effects Model, Hyperamylasemia, Incidence, Meta Analysis, Meta-Analysis, Metaanalysis, Methods, Model, Multicenter, P, Pancreatic Stent, Pancreatic Stents, Pancreatitis, Patients, Post-Ercp Pancreatitis, Prevent, Prophylactic, Publishing, Pubmed, Quality, Quality Of, Randomized, Randomized Controlled Trials, Randomized Controlled-Trial, Reduce, Reviewers, Rights, Science, Science Citation Index, Scoring System, Screening, Software, Stents

? Palomba, S., Sereni, G., Falbo, A., Beltrami, M., Lombardini, S., Boni, M.C., Fornaciari, G., Sassatelli, R. and La Sala, G.B. (2014), Inflammatory bowel diseases and human reproduction: A comprehensive evidence-based review. World Journal of Gastroenterology, 20 (23), 7123-7136.

Full Text: 2014\Wor J Gas20, 7123.pdf

Abstract: To evaluate the effects of inflammatory bowel diseases (IBDs) on human reproduction, we reviewed the current literature using a systematic search for published studies (articles and/or abstracts) without limits for English language. We searched on Medline (through PubMed), the Institute for Scientific Information, the Web of Science and the websites for the registration of controlled trials (http://controlled-trials.com/). Bibliographies of retrieved articles, books, expert opinion review articles and reviewed bibliographies from subject experts were manually searched. Titles and abstracts were screened initially, and potential relevant articles were identified and reviewed. Whenever possible, data were analyzed by comparing IBD patients vs healthy controls, and patients with active IBDs vs those with disease in remission. The effects of IBDs on female fertility, fertility in infertile couples, pregnancy and male infertility were examined separately. Patients with IBDs in remission have normal fertility. At the moment, there is no established guideline for the preservation of fertility in women with IBD undergoing surgery. Further data are needed regarding guidelines for the management of these patients. Data regarding IBDs and infertility are currently completely lacking. Considering the prevalence of intestinal pathology in young adults of childbearing age, this field is of great scientific and clinical interest, opening up important future perspectives. Another important and as yet unexplored point is the response to treatments for infertility in patients with IBDs. In particular, the question is whether the reproductive outcomes (clinical and biological) can be influenced by the IBD of one of the partners. The goals for successful reproductive outcomes in IBD population are correct counseling and disease remission. IBDs significantly affect several reproductive aspects of human (female, male, couple) reproduction. Further data are needed to develop guidelines for the clinical management of subjects of reproductive age with IBDs. (C) 2014 Baishideng Publishing Group Inc. All rights reserved.

Keywords: Age, Articles, Bibliographies, Biological, Bowel, Childbearing, Clinical, Clinical Management, Couple, Couples, Crohns-Disease, Danish Nationwide Cohort, Data, Disease, Diseases, Effects, English, Evidence Based, Evidence-Based, Expert Opinion, Experts, Female, Fertility, Field, Guideline, Guidelines, Human, Human Reproduction, Ibd, Induced Seminal Abnormalities, Infertility, Inflammatory Bowel Diseases, Information, Institute For Scientific Information, Language, Literature, Male, Male-Fertility, Management, Medline, Necrosis-Factor-Alpha, Normal, Of-The-Literature, Outcomes, Pathology, Patients, Population, Potential, Pouch-Anal Anastomosis, Pregnancy, Preservation, Prevalence, Publishing, Pubmed, Reproduction, Reproductive Outcomes, Response, Reversible Male-Infertility, Review, Rights, Science, Sexual Function, Surgery, Systematic, Titles, Ulcerative-Colitis, Web Of Science, Websites, Women, Young Adults

? Eshraghian, A. and Jahromi, A.H. (2014), Non-alcoholic fatty liver disease and thyroid dysfunction: A systematic review. World Journal of Gastroenterology,