Title: Yearbook of Physical Anthropology

Title: Yonsei Medical Journal

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? Wang, J., Guo, X.F., Zhang, J.X., Song, J., Ji, M.Y., Yu, S.J., Wang, J., Cao, Z. and Dong, W.G. (2013), Cyclooxygenase-2 polymorphisms and susceptibility to colorectal cancer: A meta-analysis. Yonsei Medical Journal, 54 (6), 1353-1361.

Full Text: 2013\Yon Med J54, 1353.pdf

Abstract: Purpose: Four polymorphisms, -765G>C, -1195G>A, 8473T>C, and Val511Ala, in the cyclooxygenase-2 (COX-2) gene were identified to be associated with colorectal cancer (CRC) risk. However, the results are inconsistent. The objective of this meta-analysis was to evaluate the association between these four polymorphisms and the risk of CRC. Materials and Methods: All eligible case-control studies published up to December 2012 on the association between the four polymorphisms of COX-2 and CRC risk were identified by searching PubMed and Web of Science. The CRC risk associated with the four polymorphisms of the COX-2 gene was estimated for each study :by odds ratio (OR) together with its 95% confidence interval (CI), respectively. Results: A total of 15 case-control studies were included. Overall, no evidence has indicated that the -1195A allele, -765C allele, 8473C allele, and 511Ala allele are associated with susceptibility to CRC (-1195G>A: OR=1.11, 95% CI: 0.82-1.51,p=0.78; -765G>C: OR=1.08, 95% CI: 0.96-1.21, p=0.07; 8473T>C: OR=1.03, 95% CI: 0.89-1.18, p=0.91; Val511Ala: OR=0.71, 95% CI: 0.46-1.09, p=0.94). However, stratified analysis with ethnicity indicated that individuals with -765GC or GC/CC genotypes had an increased risk of CRC among Asian populations (GC vs. GO: OR=1.05, 95% CI: 0.87-1.28, p=0.03; GC+CC vs. GG: OR=1.08, 95% CI: 0.96-1.21, p=0.07). Conclusion: This meta-analysis indicated that -765G>C polymorphism was significantly associated with susceptibility to CRC in Asian populations.

Keywords: 3’-Untranslated Region, African-Americans, Analysis, Article, Asian, Association, Cancer, Carcinogenesis, Case-Control, Case-Control Studies, China, Colon-Cancer, Colorectal, Colorectal Cancer, Confidence, Cox-2, Cox-2 Polymorphisms, Cyclooxygenase-2, Ethnicity, Evidence, Gastrointestinal-Tract, Gene, Gene-Expression, Go, Interval, Korea, Materials, Medicine, Messenger-Rna, Meta Analysis, Meta-Analysis, Metaanalysis, Methods, Nov, Odds Ratio, pH, Polymorphism, Polymorphisms, Populations, Pubmed, R, Results, Risk, Science, South, South-Korea, Variant, Web of Science

? He, L., Deng, T. and Luo, H.S. (2015), Efficacy and safety of endoscopic resection therapies for rectal carcinoid tumors: A meta-analysis. Yonsei Medical Journal, 56 (1), 72-81.

Full Text: 2015\Yon Med J56, 72.pdf

Abstract: Purpose: Several endoscopic resection therapies have been applied for the treatment of rectal carcinoid tumors. However, there is currently no consensus regarding the optimal strategy. We performed a meta-analysis to compare the efficacy and safety of endoscopic mucosal resection (EMR) or modified EMR. (m-EMR) versus endoscopic submucosal dissection (ESD) for the treatment of rectal carcinoid tumors. Materials and Methods: PubMed, Web of Science, Medline, Embase and CNKI were searched up to the end of January 2014 in order to identify all studies on the effects of EMR (or m-EMR) and ESD on rectal carcinoid tumors. Results: A total of fourteen studies involving 782 patients were included. The pooled data suggested a significantly higher rate of pathological complete resection among patients treated with ESD or m-EMR. than those treated with EMR [odds ratio (OR)=0.42, 95% confidence interval (CI): 0.25-0.71; OR=0.10, 95% CI: 0.03-0.33, respectively], while there was no significant difference between the m-EMR group and ESD group (OR=1.19, 95% CI: 0.49-2.86); The procedure time of ESD was longer than EMR or m-EMR groups [mean differences (MD)=-11.29, 95% CI: -14.19 - -8.38, MD= -10.90, 95% CI: -18.69 - -3.11, respectively], but it was insignificance between the EMR and m-EMR groups. No significant differences were detected among the treatment groups with regard to complications or recurrence. Conclusion: The results of this meta-analysis suggest that treatment of rectal carcinoid tumors with ESD or m-EMR is superior to EMR, and the efficacy of m-EMR is equivalence to ESD treatment. However, more well-designed studies are needed to confirm these findings.

Keywords: Bias, Complete, Complications, Confidence, Consensus, Data, Dissection, Effects, Efficacy, Emr, Endoscopic, Endoscopic Mucosal Resection, Endoscopic Resection, Endoscopic Submucosal Dissection, Gastroenteropancreatic Neuroendocrine Tumors, Groups, Interval, Ligation Device, Materials, Medline, Meta Analysis, Meta-Analysis, Metaanalysis, Methods, Modified, Mucosal, Mucosal-Resection, Patients, Procedure, Pubmed, Rectal, Rectal Carcinoid Tumor, Recurrence, Resection, Results, Safety, Science, Strategy, Submucosal-Dissection, Treatment, Web, Web Of Science

Title: Zdravniski Vestnik-Slovenian Medical Journal

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? Miholic, P. and Juznic, P. (2009), Social medicine in the process of scientific communication: the overview of the publications of the authors in the field of Social Medicine in Science Citation Index and Social Sciences Citation Index. Zdravniski Vestnik-Slovenian Medical Journal, 78 (4), 181-185.

Abstract: Background the scientific publishing means publishing the results of scientific research in the scientific journals. Scientific publishing is not possible without scientific communication and sharing information among scientists. Keeping up with scientific achievements and spreading them is the core of all research work. The recognition is a factor of the highest importance for the scientific publications, where in the process of scientific communications the results of the research work are published. The purpose of the research work in social medicine is to achieve the awareness, which is necessary for efficient and successful health care. Methods On the basis of the science citations database (Web of Science) the publications of researchers, who work in the field of public health, were checked. It was found out that more than a third of researchers had publications published in Science Citation Index (SCI) as well as in Social Sciences Citation Index (SSCI). Results the overlapping of analysed articled in both Indexed databases were 26%. Researching health care is a medical field with a strong social character; such research deals with medicine, health care and health is a social phenomenon. Conclusions Social medicine is one area of medical science, however, the research in this area should be valued and estimated differently as other areas of research, like clinical medicine. It would be sensible that the ARRS expert system and others, who use qualitative as well as quantitative, bibliometric methods for judging the quality and recognition of research work, take this into account in the future.

Keywords: Citation, Citation Index, Citations, Communication, Core, Database, Databases, Field, Future, Health, Health Care, Journal Impact, Journals, Medical, Medicine, Methods, Overlapping, Public Health, Publications, Publishing, Quality, Research, Research Work, Researchers, SCI, Science, Science Citation Index, Scientific Communication, Scientific Journals, Scientific Publication, Scientific Publications, Scientific Research, Slovenia, SSCI, System, Web of Science

? Peclin, S. and Juznic, P. (2012), Research in the fields of medicine in Slovenia - research potential, funding, and publications. Zdravniski Vestnik-Slovenian Medical Journal, 81 (9), 602-617.

Full Text: 2012\Zdr Ves-Slo Med J81, 602.pdf

Abstract: Background: This study analyses funding of research from public sources, research potential (number of researchers), and scientific results (scientific papers authored or co-authored by researchers from Slovenia). Research fields of medicine are analysed in-depth and comparatively with several other research fields to gain a better understanding of differences that may be a result of long-term science policies in Slovenia. The aim of the study was to discover if relatively big differences in research potential and public funding are also reflected in the number of scientific papers and their impact. Methods: Research potential was defined as the number of research groups and number of researchers (head count) and expressed in their capacities to research in FTE (full time equivalent). Research results data was analysed and evaluated basically as bibliometric data, that is, the number of papers published in ISI - indexed journals and their impact measured by the number of citations. Quantitative indicators used for the evaluation of research results were divided in two groups: indicators of scientific activities and indicators of scientific productivity and impact. We analysed investment from public sources into government and higher education sectors’ research more thoroughly as that was the research, which was the focus of our interest. Scientific papers are mostly the result of the performance in higher education sector and government sector. Results: Differences in research potential and public funding only partly influence the number of scientific papers but might have more to do with their impact. The results show that the number of papers published with the authorship or co-authorship of researchers from Slovenia is rapidly increasing, especially in the subfields of clinical medicine. Comparison of the number of papers per million inhabitants puts Slovenia slightly above the EU average, but in terms of impact or the average number of citations received per article, Slovenia is in penultimate place among EU Member States. Conclusions: the size of the human research potential in the fields of medicine in Slovenia is modest. The majority of researchers are also engaged in medical practice and education. Consequently, funds from public sources for research per researcher are low. Research fields of medicine primarly require an increase in human research resources, which can then provide a basis for a rise in funding and the impact of its research results becoming comparable to the EU and world averages.

Keywords: Analyses, Authorship, Basic Research, Bibliometric, Bibliometric Indicators, Biomedical Research, Citations, Clinical, Co-Authorship, Coauthorship, Comparison, Data, Education, EU, Evaluation, Funding, Higher Education, Human, Impact, Indicators, ISI, Journals, Long Term, Long-Term, Medical, Medical Practice, Medicine, Papers, Performance, Policies, Potential, Practice, Productivity, Public, Public Funds, Publications, Research, Research Policy, Research Results, Resources, Science, Scientific Activities, Scientific Productivity, Sector, Size, Slovenia, Sources, Understanding, World