Rebecca B. Riggins, Ph. D
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| Rebecca B. Riggins, Ph.D.
Georgetown University Medical Center E412 New Research Building 3970 Reservoir Road, NW Washington, DC 20057 (202) 687-1260 (office) (202) 687-5503 (lab) (202) 687-7505 (fax) Riggins Lab Website Education Hood College, Frederick, MD B.A., Biochemistry, cum laude 8/1994 – 5/1998 University of Virginia, Charlottesville, VA Ph.D., Microbiology 8/1998 – 5/2003 Georgetown University, Washington, DC Postdoctoral Fellowship, Oncology 6/2003 – 9/2006 Professional Experience Research Track Assistant Professor, Department of Oncology 9/2006 – 12/2010 Breast Cancer Program Lombardi Comprehensive Cancer Center, Georgetown University, Washington, DC
Breast Cancer Program Lombardi Comprehensive Cancer Center, Georgetown University, Washington, DC *Time in service towards tenure eligibility began 7/1/2011 Honors and Awards National Science Foundation Graduate Research Fellowship Program, 1998 Honorable Mention
Pre-doctoral Trainee, University of Virginia Selected to attend the Edward A. Smuckler Pathobiology of Cancer Workshop, 2001 Keystone, CO (sponsored by the American Association for Cancer Research) NIH-funded Tumor Biology Training Grant, T32-CA09686 2003 – 2004 Postdoctoral Trainee, Lombardi Comprehensive Cancer Center Selected to attend the Susan G. Komen Breast Cancer Career Mentoring 2005 Program for Postdoctoral Fellows Fourth Annual Future of Breast Cancer Congress: Individualizing Breast Cancer Treatment, Southampton, Bermuda Postdoctoral Division Finalist, 20th Annual Student Research Days Competition, 2006 Office of Biomedical Graduate Education, Georgetown University Invited to attend the 2007 Annual Meeting of the Cancer Biology Training 2007 Consortium (CABTRAC), Vergennes VT Invited Delegate, 2009 Controversies in Breast Cancer Meeting, 2009 Edinburgh, U.K. Appointed to the Executive Advisory Board for the U.K. Breast Cancer 2012 Campaign Gap Analysis, 2012-2013 Finalist, Gerald M. Mara Faculty Mentorship Award, Georgetown University 2014 John Eisenberg Career Development Award, Georgetown Women in Medicine 2014 Selected to attend the Association of American Medical Colleges 2014 (AAMC) Early Career Women Faculty Professional Development Seminar, Englewood, CO
Georgetown University Professional Societies Member, American Association for Cancer Research (AACR) 2001 – present and Women in Cancer Research (WICR)
American Association of Medical Colleges (AAMC) Public Service Ad Hoc Manuscript Reviewer: Cancer Research, Clinical Cancer Research, 2005 – present BMC Cancer, Nutrition & Cancer, Expert Reviews in Molecular Medicine, Breast Cancer Research and Treatment, Anti-Cancer Drug, Breast Cancer Research, Genome Medicine, Endocrine-Related Cancer, Molecular and Cellular Endocrinology, Molecular Cancer Therapeutics, Oncogene, American Journal of Pathology, PloS ONE, Nanomedicine, Cell Proliferation Ad Hoc Grant Reviewer, Dutch Cancer Society (KWF Kankerbestrijding), 2006 - 2009 Breast Cancer Campaign (U.K. and Republic of Ireland), Health Research Board Ireland, Florida Department of Health
Research Program (BCRP) TRN-CBY, IPD-CBY, and IIT panels Ad Hoc Study Section Member, National Institute of Environmental 2011 Health Sciences (NIEHS) Special Emphasis Panel ZES1 LWJ-J-(DI)1 Editorial Board member, Frontiers in Pharmacology of Anti-Cancer Drugs 2011- present Ad Hoc Study Section Member, National Cancer Institute (NCI) 2012 Special Emphasis Panel for review of Provocative Questions RFA CA-11-011 and -012
the Translational Breast Cancer Research Consortium Outreach/Media Relations AACR 100th Annual Meeting Promotional Video 2009 “History of the American Association for Cancer Research” http://www.youtube.com/watch?v=whxZb0OS_bE&list=UUxr_bGdhkdyyFo5V3qDBwGg Office of the Director, National Institutes of Health (NIH) 2009 American Recovery and Reinvestment Act (ARRA) Research Funding Promotional Video http://recovery.nih.gov/Stories/ViewStory.aspx?id=454 AACR 102nd Annual Meeting Public Policy Press Conference on 2011 Federal funding for cancer research http://traffic.libsyn.com/aacr/AACR_Public_Policy_Press_Conference.mp3
funding
http://www.bloomberg.com/news/2013-04-04/tumors-on-ice-as-budget-impasse-freezes-medical-research.html PBS News Hour interview on effects of sequestration on Federal research 2013 funding
http://www.pbs.org/newshour/rundown/sequester-cuts-to-science-puts-medical-resarch-on-hold/ Kojo Nnamdi Show panel discussion on young scientists and the research 2015 funding crunch http://thekojonnamdishow.org/shows/2015-01-29/young_scientists_and_the_research_funding_crunch
“Finding a Home for an Orphan Nuclear Receptor” 2/21/2013 Departments of Biology and Chemistry Joint Seminar Hood College, Frederick, MD USA “Introduction to Molecular Biology for Engineers” 9/18/2013 Department of Electrical and Computer Engineering, Virginia Tech, Arlington, VA USA
Elizabeth J. Somers Women’s Leadership Program George Washington University, Washington, DC USA
Member, LCCC Genomics and Epigenomics Shared Resource 2009 - 2012 Advisory Committee, Department of Oncology
Department of Oncology
Member, Biospecimen Use Committee, Department of Oncology 2015 - present School Member, Georgetown Women in Medicine (GWIM) John Eisenberg 2015 Career Development Award Selection Subcommittee
Full Member, Georgetown University Animal Care and Use Committee 2011 – 2014 (GUACUC)
Spring 2005, 2009, 2010 BIOL 500: Dietary Cancer Prevention/Nutrition UDC/Georgetown Master’s Program in Cancer Biology, Prevention, and Control Role: Lecturer Lecture Titles: “Nutrition and Cancer Risk: Vitamins A and D,” and “Basics of Endocrinology” Two contact hours Number of Students: 4-6 Overall Evaluation Score: N/A (not administered by course director) Fall 2009 TBIO 508: Tumor Biology I, Cellular and Molecular Aspects of the Transformed Cell Tumor Biology PhD and Master’s program Georgetown University Medical Center Role: Lecturer Lecture Title: “Role of apoptosis in cancer development and therapeutic response” One contact hour Number of Students: 26 Overall Evaluation Score: 4.72 out of 5 Spring 2010 NSCI 532: Skills and Ethics to Survive and Thrive in Science Interdisciplinary Program in Neuroscience Georgetown University Medical Center Role: advisor No lecture: advisor for grant writing skills for graduate students Two contact hours Number of Students: 3 (assigned to me) Overall Evaluation Score: N/A (not administered by course director) Fall 2010 TBIO 508: Tumor Biology I, Cellular and Molecular Aspects of the Transformed Cell Georgetown University Medical Center Role: Lecturer Lecture Titles: “Growth Factors and their Receptors,” and “Hormones and Cancer” Two contact hours Number of Students: 23 Overall Evaluation Score: 4.93 out of 5
Georgetown University Medical Center Role: Lecturer Lecture Titles: “Extracellular Matrix,” and “Integrins” Two contact hours Number of Students: 10 Overall Evaluation Score: 4.78 out of 5
UDC/Georgetown Master’s Program in Cancer Biology, Prevention, and Control Role: Lecturer/Discussion Leader Lecture Title: “How to Read a Scientific Paper” One contact hour Number of students: 4 Overall Evaluation Score: N/A (not administered by course director)
Georgetown University Medical Center Role: Co-Course Director and Lecturer Lecture Title: “Growth Factors and their Receptors” One contact hour for lecture, ~35 contact hours as co-course director Number of Students: 17 Overall Evaluation Score: 5 out of 5 for lecture; co-course director evaluation not conducted
Georgetown University Medical Center Role: Faculty No lecture: lead journal club-style discussion of recent paper One contact hour Number of students: 4 Overall Evaluation Score: N/A (not administered by course director)
Georgetown University Medical Center Role: Lecturer Lecture Titles: “Extracellular Matrix,” and “Integrins” Two contact hours Number of Students: 9 Overall Evaluation Score: 4.486 out of 5
Georgetown University Medical Center Role: Co-Course Director and Lecturer Lecture Title: “Biochemical principles of growth factor signaling” One contact hour for lecture, ~40 contact hours as co-course director Number of Students: 23 Overall Evaluation Score: 4.81 out of 5 for course director role; 4.84 out of 5 for lecturer role
Georgetown University Medical Center Role: Lecturer Lecture Title: “Oxidative metabolism, mitochondria, and reactive oxygen species,” and a second lecture on the practical application of these concepts in the laboratory Two contact hours Number of Students: 12 Overall Evaluation Score: 4.97 out of 5
Georgetown University Medical Center Role: Lecturer Lecture Title: Orphan Nuclear Receptors 0.5 contact hours Number of Students: 30 Overall Evaluation Score: N/A (not administered by course director)
Georgetown University Medical Center Role: Faculty No lecture: lead journal club-style discussion of recent paper One contact hour Number of students: 4 Overall Evaluation Score: N/A (not administered by course director)
Georgetown University Medical Center Role: Lecturer Lecture Titles: “Extracellular Matrix,” and “Integrins” Two contact hours Number of Students: 13 Overall Evaluation Score: 4.66 out of 5
Georgetown University Medical Center Role: Co-Course Director and Lecturer Lecture Title: “Biochemical principles of growth factor signaling” One contact hour for lecture, ~50 contact hours as co-course director Number of Students: 26 Overall Evaluation Score: 4.94 out of 5 for course director role; 4.91 out of 5 for lecturer role
Georgetown University Medical Center Role: Lecturer Lecture Title: “Oxidative metabolism, mitochondria, and reactive oxygen species,” and a second lecture on the practical application of these concepts in the laboratory Three contact hours Number of Students: 12 Overall Evaluation Score: 4.9 out of 5
Georgetown University Medical Center Role: Lecturer Lecture Title: Orphan Nuclear Receptors 0.5 contact hours Number of Students: 30 Overall Evaluation Score: N/A (not administered by course director)
Georgetown University Medical Center Role: Faculty No lecture: lead journal club-style discussion of recent paper One contact hour Number of students: 5 Overall Evaluation Score: N/A (not administered by course director)
Georgetown University Medical Center Role: Lecturer Lecture Titles: “Extracellular Matrix,” and “Integrins” Two contact hours Number of Students: 17 Overall Evaluation Score: 4.75 out of 5
Georgetown University Medical Center Role: Co-Course Director and Lecturer Lecture Title: “Biomolecular Interactions” One contact hour for lecture, ~50 contact hours as co-course director Number of Students: 17 Overall Evaluation Score: 4.8 out of 5 for course director role; TBD for lecturer role
Georgetown University Medical Center Role: Lecturer Lecture Title: “Oxidative metabolism, mitochondria, and reactive oxygen species,” and a second lecture on the practical application of these concepts in the laboratory Three contact hours Number of Students: 12 Overall Evaluation Score: TBD
Georgetown University Medical Center Role: Lecturer Lecture Title: Targeting ETS Family Transcription Factors in Triple Negative Breast Cancer 0.5 contact hours Number of Students: 30 Overall Evaluation Score: N/A (not administered by course director)
Georgetown University Medical Center Role: Faculty No lecture: lead journal club-style discussion of recent paper One contact hour Number of students: 5 Overall Evaluation Score: N/A (not administered by course director)
Georgetown University Medical Center Role: Lecturer Lecture Titles: “Extracellular Matrix,” “Integrins,” and Three contact hours Number of Students: 17 Overall Evaluation Score: 4.79 out of 5
Spring 2004 BIOL 395: Topics in Cancer Causes and Prevention Undergraduate course, University of the District of Columbia, Washington, DC Role: Lecturer Lecture Title: “Phytoestrogens, Hormone Replacement and Oral Contraceptives” Two contact hours Number of Students: 8 Overall Evaluation Score: N/A (not administered by course director) Fall 2005,2006,2008 BIOL 495: Cellular and Molecular Aspects of the Transformed Cell Undergraduate course, University of the District of Columbia, Washington, DC Role: Lecturer Lecture Titles: “Growth Factors, Receptors, and Signal Transduction I and II” Four contact hours (two hours per lecture) Number of Students: 10-12 Overall Evaluation Score: N/A (not administered by course director) Summer 2006 – 2010, 2014 Brown Bag Seminar Series (for summer research students) Georgetown University Medical Center Role: Lecturer Lecture Titles: “Apoptosis, Cell Survival, and Cancer,” “Nuclear Receptors and Cancer” One contact hour Number of Students: 15-20 Overall Evaluation Score: N/A Mentoring Undergraduate Students Jonathan Roberts: I mentored Jon during the 2003-2004 academic year as he completed his Biology Department undergraduate Senior Thesis entitled “Retinoid Resistance in Breast Cancer” in Dr. Robert Clarke’s lab. This included training him in new laboratory techniques, teaching him how to interpret data, and guiding him in writing the thesis. Jon graduated from Georgetown in 2004, worked as a technician in Dr. Clarke’s lab for one year, then entered medical school at Temple University in the fall of 2005. Haniee Chung: I mentored Haniee from January 2004 through May of 2005, during which time she began and completed her Biology Department undergraduate Senior Thesis entitled “The Role of Interferon Regulatory Factor-1 in Breast Cancer Cell Response to Antiestrogens” in Dr. Robert Clarke’s lab. In addition to developing strong skills in several laboratory techniques, data interpretation, and scientific writing, Haniee orally presented her work and was a finalist in the Student Division of the 2005 Student Research Days Competition, sponsored by the Office of Biomedical Graduate Education. Haniee is a co-author on a paper published in Molecular Cancer Therapeutics in 2010. Haniee graduated from Georgetown in May 2005, worked for one year as a research assistant in the Department of Neurology at Johns Hopkins University, and entered Georgetown School of Medicine in the fall of 2006. She is now in the General Surgery residency program at Washington University of St. Louis. Jennifer Pei-Jen Lan: I mentored Jennifer from January through August 2005, before she began a yearlong study abroad program at Oxford University in the U.K. Jenn then rejoined the lab for the 2006-2007 academic year in order to complete her Biology Department undergraduate Senior Thesis, where she investigated the role of estrogen-related receptor gamma (ERRγ) in estrogen dependence and antiestrogen resistance. She is second-author on our 2008 Cancer Research publication. Jen graduated from Georgetown in May 2007 and entered Georgetown School of Medicine in the fall of 2007. She is currently an Allergy/Immunology Fellow at the University of Tennessee Health Science Center in Memphis, TN. Jennifer Mulla: Jennifer was a Human Biology major in the School of Nursing and Health Sciences. She began working with me in Dr. Clarke’s lab during the spring semester of 2006, studying the molecular mechanism(s) of apoptosis that are regulated by Interferon Regulatory Factor-1, and she is a co-author our 2010 Molecular Cancer Therapeutics paper. During her junior year (2007), Jenn received the Charles H. Evans, Jr. Award for best poster presentation at the Georgetown University Undergraduate Research Conference; in her senior year, she received this award again for the best oral presentation. Jenn received her degree in May 2008, was accepted into the NIH Post baccalaureate IRTA program in the laboratory of Dr. Douglas Lowy, and entered medical school at Eastern Virginia Medical School in 2010. She is now in the Pediatric residency program at Children’s Hospital of The King’s Daughters in Norfolk, VA. Omar Maniya: Omar was a Biology major who began working in the lab as a sophomore during the spring semester of 2009 in preparation for his undergraduate Senior Thesis work. He studied the role of orphan nuclear receptors in multiple models of Tamoxifen resistance. Omar was accepted into Georgetown School of Medicine’s Early Assurance Program during his sophomore year, and he is a co-author on our review of orphan nuclear receptors in breast cancer published in Endocrine-Related Cancer (2010). Omar entered Georgetown School of Medicine in the fall of 2011, and is part of the dual-degree MD/MBA program. Loubna Elhelu: Loubna was a Biology major at the University of the District of Columbia who worked in my lab for one year during her sophomore year (2009-2010). In collaboration with Dr. Deepak Kumar (Associate Professor at UDC with a joint appointment to the Department of Oncology at Georgetown), Loubna studied the role of the endocrine disruptor Bisphenol A in regulating growth and gene expression in normal mammary epithelial cells. Sara Alnoor: Sara was a Biology major at George Mason University. Sara performed an independent study in my lab during the 2011-2012 academic year, where she studied the regulation of cell migration and adhesion by the orphan nuclear receptors ERR and ERR in glioblastoma. She is currently an embryology lab assistant at Shady Grove Fertility. Alex Farzanegan: Alex is a rising sophomore at Penn State University, and worked in my lab for the summer months of 2014 through the LCCC Summer Research Volunteer Program. Working together with my former graduate student and postdoctoral fellow Mary Heckler, Alex studied DY131/ERRβ signaling in triple negative breast cancer. MS Students Cara Schafer: Cara was a Master’s student in the Department of Biochemistry and Molecular Biology. During the 2009-2010 academic year, Cara performed her internship in my lab during the spring semester, where she studied the combined effects of a high fat diet and neonatal BPA exposure on measures of Type 2 diabetes and insulin resistance in female rodents. Cara then joined my lab as a full-time Research Assistant from June 2010 through June 2011. She is currently a PhD candidate in the Cancer Biology Graduate Program at the University of Alabama-Birmingham. Cara is a co-author on our FEBS Journal publication (2014). Pharah Morgan: Pharah was a Master’s student in the Tumor Biology Program in the Department of Oncology, and among the first in the program’s new Cancer Systems Biology Track. She performed her Spring 2013 internship in my lab from January through April 2013, where her work focused on mapping and screening putative target genes of ERR in ER+, endocrine resistant breast cancer. Pharah went on to obtain a Master’s of Public Health at the University of Arizona, and she is now a Health Program Manager at the Navajo County Department of Public Health in Holbrook, AZ. Tizita Zeleke: Tizita was a Master’s student in the Tumor Biology Program, Cancer Systems Biology Track, in the Department of Oncology. She began her internship in my lab in October 2013, where she remained until April 2014. Tizita studied the role of DY131/ERRβ signaling in triple negative breast cancer in African American women. Tizita worked as a patient navigator at the Capital Breast Care Center in Washington, DC for one year before joining the PhD program at Mt. Sinai in the summer of 2015. Nataly Naser Al Deen: Nataly is a Master’s student in the Tumor Biology Program in the Department of Oncology. She began her internship in my lab in October 2014, where she studied the functional interaction between the tumor suppressor p53 and inhibition of ETS family function by the small molecule YK-4-279. Nataly joined the PhD program in Cell and Molecular Biology at the American University of Beirut in the summer of 2015. Catherine Aldrich: Catherine is a Master’s student in the Tumor Biology Program in the Department of Oncology. She began her internship in my lab in October 2014, where she helped to analyze the function of the ERRβ2 splice variant carboxyl-terminus. Catherine is currently a Biomarker Scientist at Pfizer. Directory: data -> people people -> Victor d. Cha people -> Laura Anderko Phd rn professor Robert and Kathleen Scanlon Endowed Chair in Values Based Health Care Director, Mid-Atlantic Center for Children’s Health and the Environment people -> Domestic Institutions Beyond the Nation State: Charting the New Interdependence Approach people -> Review of International Political Economy people -> Transatlantic Flight Fights people -> Work experience people -> Meredith K. McKittrick people -> Michael a. Stoto Download 162.47 Kb. Share with your friends:
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