Representative Publications:
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Tonya Hendrix , Rajendra Chilukuri, Marcia Martinez, Zachariah Olushoga, Andrew Blake, Moazzam Brohi, Christopher Walker, Michael Samms Jerry Guyden. Thymic nurse cells exhibit epithelial progenitor phenotype and create unique extra-cytoplasmic membrane space for thymocyte selection. Cell Immuno 261: 81-92 2010
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Martinez, M., Samms, M., Hendrix, T.M., Oluwaseun, A., Pezzano, M., and Guyden, J.C. 2007. Thymic nurse cell multicellular complexes in HY-TCR transgenic mice demonstrate their association with MHC restriction. Exp. Biol. Med. 232:780-788.
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Webb, O., Kelly, F., Benitez, J., Li, J., Parker, M., Martinez, M., Samms, M., Blake, A., Pezzano, M. and Guyden, J.C. 2004. The identification of thymic nurse cells in vivo and the role of cytoskeletal proteins in thymocyte internalization. Cellular Immunology. 228: 119-129.
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Martinez, M., Pramanik, A., Moto-Ndje, S. and Moore, C.W. 2003. Overexpression of genes involved in vesicular trafficking to the vacuole defends against lethal effects of oxidative damage. Cell. and Molec. Biol. 49(7): 1025-1035.
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Martinez, M., Pramanik, A., McKoy, J., Robert, K. and Moore, C.W. 2003. Pleiotropic cellular deficiencies conferred by the blm5-1 mutation of Saccharomyces cerevisiae. Cell. and Molec. Biol. 49(7): 1049-1056.
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Pezzano, M., Samms, M., Martinez, M., and Guyden, J. 2001. Questionable thymic nurse cell. Microbiol. and Molec. Biol. Rev. 65(3): 390-403.
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Samms, M., Martinez, M., Fousse, S., Pezzano, M. and Guyden, J.C. 2001. Circulating macrophages as well as developing thymocytes are enclosed within thymic nurse cells. Cellular Immunology. 212: 16-28.
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Moore, C.W., McKoy, J., Dardalhon, M., Davermann, D., Martinez, M., and Averbeck, D. 2000. DNA damage-inducible and RAD52-independent repair of DNA double-strand breaks in Saccharomyces cerevisiae. Genetics. 154: 1-13.
Biology
OKUMUResearch Fields:
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Reproductive Physiology
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Endocrinology
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Ovarian and uterine cancers
Collaborations:
Department of Biomedical sciences, CVMNAH, Tuskegee University
Department of Biomedical Sciences, CVMNAH, Tuskegee University
Department of Pathobiology, CVMNAH, Tuskegee University
Lilian A. Okumu, Ph.D.
Assistant Professor, Biology
E-mail: lokumu@mytu.tuskegee.edu
Office phone: 334-727-4980
Office Address: Armstrong Hall, Room 209, Tuskegee, AL 36088
Biographical Sketch:
Biographical Sketch:
Dr. Lilian Okumu is currently an Assistant Professor in Biology. She obtained her Bachelor of Science degree in Biomedical Science and Technology at Egerton University, Kenya, and a PhD in Reproductive Physiology at University College Dublin, Ireland. She has worked as a post-doctoral fellow for two and a half years, at Tuskegee University’s Centre for Veterinary Medicine, Nursing and Allied Health. Her research is focused on elucidating the effects of endocrine disrupting chemicals on the development of the male and female reproductive structures. She is also focused on deciphering possible intervention/ therapeutic targets in ovarian and uterine cancers. She previously taught Animal Production and Physiology as a graduate student at UCD and co-taught Microanatomy (Histology) to first year DVM students at Tuskegee University’s Veterinary School.
Representative Publications:
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Okumu L.A., Forde N., Mamo S., McGettigan P.A., Mehta J.P., Roche J.F., Lonergan P. Temporal Regulation of Fibroblast Growth Factors in the Bovine Endometrium and Conceptus. Reproduction. 2014 Feb 19. [Epub ahead of print] PMID:24554351
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Okumu L.A., Braden T.D., Vail K., Simon L., Goyal H.O. Low Androgen-Induced Penile Mal-development Involves Altered Gene Expression For Biomarkers For Smooth Muscle Cell Differentiation and a Key Enzyme Regulating Cavernous Smooth Muscle Tone J Urol. 2013 Dec 6. doi: 10.1016/j.juro.2013.11.101. [Epub ahead of print] PMID: 24316094
Biology
TROYResearch Fields:
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Cancer Biology
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Health Disparities
Collaborations:
College of Arts and Sciences, Dept. of Psychology & Sociology, Tuskegee University
College of Arts and Sciences, Dept. of Biology, Tuskegee University
College of Arts and Sciences, Dept. of Chemistry, Tuskegee University
Roberta M. Troy, Ph.D.
Founding Director, Health Disparities Institute for Research & Education; Associate Professor of Biology-College of Arts & Sciences
E-mail: rmtroy@mytu.tuskegee.edu
Office 334-725-2364, Fax 334-724-3919
Office Address: 70-112 John A. Kenney Hall, Tuskegee, AL 36088
Biographical Sketch:
Roberta M. Troy earned the B.S. and M.S. degrees in biology from Tuskegee University, and the Ph.D. in biochemistry and molecular biology from the University of Florida, where she was a McKnight Pre-doctoral Fellow. Subsequently, Troy continued her training at the Cleveland Clinic Foundation, where she was a postdoctoral fellow in molecular virology. She currently serves as the founding director of the Health Disparities Institute for Research and Education (HDIRE) at Tuskegee University and teaching faculty in genetics, cell biology and health disparities. Prior to that appointment, Troy served the university in other capacities: interim provost, director of the SACS-required Quality Enhancement Plan (QEP), assistant provost for undergraduate studies, Chair of the faculty senate and head of the Department of Biology. Her research area has focused on chemotherapeutic effects of natural products on breast and cervical cancer cells in African-American women specifically examining the effect on proteins involved in tumor cell invasion and cell immortality.
Representative Publications:
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Apalangya, V.A., Bakupog, T., Tutson, C., Sefadzi, S., Early, B., Troy, R.M., Curry, M.L., Robinson, P.M.L., Powell, N.L. and Russell, A.E. (2012). Inhibition of MDA-MB-231 breast cancer cell proliferation by simple diphenyl chalcone and its chlorinated derivatives. Research & Reviews: J. Oncology and Hematology. 1(2): 1-6.
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Cunningham, J., Carter, V., Troy, R., and Davis, C. (2012). A Survey of Risk Behaviors associated with the Human Papillomavirus among African-American Female College Students in Alabama. ASAPHERD Journal. 32 (2): 18-27.
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Taylor, T.N., Dean, D., Troy, R., and Leggett-Robinson, P.M. (2007). An Investigation of Cellular Toxicity of Carbon Nanomaterials in African American Breast Cancer Cells. NSTI-Nanotech 2: 345-347.
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