Definition of Diabetes mellitus (DM)



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4
Types of Diabetes
1. Type 1 Diabetes Mellitus
2. Type 2 Diabetes Mellitus
3. Gestational Diabetes
4. Other types Secondary Diabetes Mellitus
1. Type 1 diabetes:
Autoimmune disease”

• Was previously called insulin-dependent diabetes mellitus (IDDM) or juvenile- onset diabetes.
• Type 1 diabetes develops when the body's immune system destroys pancreatic beta cells, the only cells in the body that make the hormone insulin that regulates blood glucose.
Autoantibodies, mainly B-lymphocytes, against B cells of pancreas.
• Due to
1. Genetic defect
2. Infection such as coxsackievirus
3. Environmental
4. Radiation
• This form of diabetes usually strikes children and young adults, although disease onset can occur at any age.
• Type 1 diabetes may account for 5% to 10% of all diagnosed cases of diabetes.
• Risk factors for type 1 diabetes may include autoimmune, genetic, and environmental factors.

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