Disorders of blood coagulation can result in to uncontrolled haemorrhaging into joints, muscles and deep tissues with the formation of haematomas. Coagulation disorders may be classified into 2 categories:
Haemophilia A due to deficiency of anthaemophilic factor (factor VIII). It is the commonest hereditary coagulation disorder.
Haemophilia B (Christmas disease) due to deficiency of factor IX.
Von-Willebrands disease caused by deficiency or abnormality of the Von-Willebrands factor resulting in a defect of platelet adhesion.
NB: Haemophilia is carried by females and affect males