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BCH 302 METABOLISM OF NUCLEIC ACIDS (2 Units)

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BIOCHEMISTRY CURRICULUM
Lecture note on Statistics for Physical, Lecture note on Statistics for Physical, OB

BCH 303 METABOLISM OF LIPIDS (2 Units)
BCH 304 MEMBRANE BIOCHEMISTRY (1 Unit)
BCH 305 METABOLISM OF CARBOHYDRATES (2 Units)

BCH 302 METABOLISM OF NUCLEIC ACIDS (2 Units) Genome organisation and biosynthesis of proteins. Metabolism of purines and pyrimidines, nucleosides and nucleotides;
Catabolism of polynucleotide, Purines and Pyrimidines. DNA replication and repair (DNA template, primer, replicon, helicase, leading strand, lagging strand, Okazaki strand, Types of damage to DNA and mechanism of repair -xeroderma pigmentation and skin cancer. . Abnormalities in nucleic acid metabolism- Gout, immune deficiency.
BCH 303 METABOLISM OF LIPIDS (2 Units)
Classification of lipids - fatty acids, triglycerides, gycosylglyceroles, phospholipids, waxes, prostaglandins. Structure, function, biosynthesis and catabolism of different classes of lipids fatty acids, glycerides and phosphoglycerides, prostaglandins, terpenoids and steroids such as bile acids, steroid hormones, carotenoids and vitamin A, vitamin D and terpenoid quinines. Lipid micelles, monolagers bilayers Lipoprotein systems. Oxidation and synthesis of fatty acids cholesterol synthesis. Formation of ketone bodies. Integration of lipid metabolism. Acetic acid as a central precursor for biosynthesis of lipids.

BCH 304 MEMBRANE BIOCHEMISTRY (1 Unit)
Structure, composition and functions of biological membranes. Isolation, characterization and classification of membranes chemistry and biosynthesis of membranes. Molecular organization of membrane components. Natural and artificial membrane bilayers - the unit membrane hypothesis. Membrane transport system - active versus passive transport systems. Transport of sugars and amino acids ionophores.
BCH 305 METABOLISM OF CARBOHYDRATES (2 Units)
Degradation and digestion of carbohydrates - sugars, storage polysaccharides and cell walls. Reactions of sugars. Glycolysis, the Tricarboxylic acid cycle, the phosphogluconate pathway the glyoxylate pathway the pentose phosphate pathway and the cori cycle the calvin pathway.
Gluconeogenesis and glyconeogenesis. Disorders of carbohydrate metabolism.

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