An assessment of nucleic acid amplification testing for active mycobacterial infection
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Incidence of TB based on WHO estimates from 2012 AFB = acid-fast bacilli; BAL = bronchoalveolar lavage; HIV = human immunodeficiency virus; NAAT = nucleic acid amplification test; TB = tuberculosis 
Figure 49 Forest plot of the sensitivity and specificity of AFB and NAAT compared with culture or a clinical reference standard in diagnosing NTM infections a Estimated pooled values were obtained using the metan command in Stata 12.1 Incidence of TB based on WHO estimates from 2012 AFB = acid-fast bacilli; CRS = clinical reference standard; HIV = human immunodeficiency virus; MAC = Mycobacterium avium complex; NAAT = nucleic acid amplification test; NTM = non-tuberculous mycobacteria  of NAAT compared with culture, based on HIV and AFB status" align="bottom" width="751" height="497" border="0">
Figure 50 Forest plot of the sensitivity and specificity of culture compared with a clinical reference standard and subgroup analysis of NAAT compared with culture, based on HIV and AFB status a Estimated pooled values were obtained using the metan command in STATA 12.1 Incidence of TB based on WHO estimates from 2012 AFB = acid-fast bacilli; CRS = clinical reference standard; HIV = human immunodeficiency virus; MAC = Mycobacterium avium complex; NAAT = nucleic acid amplification test; NTM = non-tuberculous mycobacteria.
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