An assessment of nucleic acid amplification testing for active mycobacterial infection



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Incidence of TB based on WHO estimates from 2012: high incidence = > 100 cases per 100,000 people. The combined values are for all studies in both Figures 41 and 42.

NAAT = nucleic acid amplification test; TB = tuberculosis



Forest plot of the sensitivity and specificity of AFB plus <a href=NAAT compared with culture, grouped according to use of in-house or commercial NAAT, for studies conducted in countries with low and medium incidence of TB" align="bottom" width="928" height="510" border="0">

Figure 43 Forest plot of the sensitivity and specificity of AFB plus NAAT compared with culture, grouped according to use of in-house or commercial NAAT, for studies conducted in countries with low and medium incidence of TB

Incidence of TB based on WHO estimates from 2012: low incidence = ≤ 10 cases per 100,000 people; medium incidence = 10–100 cases per 100,000 people

AFB = acid-fast bacilli; NAAT = nucleic acid amplification test; TB = tuberculosis



Forest plot of the sensitivity and specificity of AFB plus NAAT compared with culture, grouped according to use of in-house or commercial NAAT, for studies conducted in countries with high incidence of TB

Figure 44 Forest plot of the sensitivity and specificity of AFB plus NAAT compared with culture, grouped according to use of in-house or commercial NAAT, for studies conducted in countries with high incidence of TB



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