I have established board level links with a number of global pharmaceutical and healthcare companies which has led to significant grant funding eg Glaxo Smith Kline (£3 million), Merck (£14 million), Roche (£6.5 million) GE Healthcare (£2 million) and AstraZeneca (£1 million). I was part of the Drug Development Team which won Astra Zeneca’s Oncology and Infections Visions and Values prize in 2005.
Oxford has an impressive record of protecting and developing its IPR and establishing spin out companies. When working in the University of Birmingham, I established one of their first biotechnology spin outs, a gene therapy company, COBRA Therapeutics. In Oxford, I have worked with ISIS to construct a cancer drug development company, Celleron and Oxford Cancer Biomarkers a platform technology-based biotech company which identifies chemotherapy sensitivity biomarkers.
INTERNATIONAL COLLABORATIONS:
USA I sit on NIH’s Translational Research working group as the overseas member and have established a series of collaborations with the USA’s major cancer research centres (Mayo Clinic, MD Anderson, Memorial Sloan Kettering and Dana Farber, Harvard).
INDIA having attracted grant funding from the pharmaceutical company GSK, we have constructed a network of India’s top 10 cancer centres, in partnership with Oxford. This collaboration will provide training opportunities for Indian investigators in Oxford and will build an internationally competitive clinical research network (www.indox.org.uk).
EUROPE I had the opportunity to co-chair the Entente Cordiale Celebrations on behalf of HM the Queen and President Chirac, 2003-2005. As President of ESMO (2010-2012) I am in a strong position to improve standing of Medical Oncology in Europe and sit on the Dutch government’s central committee for translational research with a budget of 1 billion Euros.
AFRICA I have established a consortium comprising the International Atomic Energy Agency, International Agency for Cancer Research, and the Union Internationals Contre Le Cancer to develop cancer control programmes in Sub Saharan Africa and created AfrOx (www.afrox.org) the vehicle to implement change.
FAR EAST I have established OxOnics, a drug development company with my colleague Dr Wenn Sun. It has a mission to bring novel anti-cancer agents to the Asia-pacific rim with a focus on China.
RESEARCH GRANTS RECEIVED
1989
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Health Board Research Support Group - £10,000.
One year's salary for Research Assistant.
as part of an international collaborative group chaired by Prof S S Davis, Dept. Pharmacy, University of Nottingham
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Cancer Research Campaign Project Grant - £160,000.
3 years' salary - clinical research fellow & post doctoral scientist for research into use of Mitomycin C microcapsules by intrahepatic arterial administration in hepatic metastatic carcinoma.
Grant Holders - D Kerr, C McArdle, A Whately.
1990
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Scottish Hospital Endowment Research Trust- £44,000
2 year's salary for research assistant - molecular biology of breast cancer
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Cancer Research Campaign - £80,000 over 3 years
Joint project with Dr I Pragnell, Beatson Institute for Cancer Research, funding a clinical research fellow to investigate preclinical toxicology of marrow stem cell inhibitor
1991
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Scottish Hospital Endowment Research Trust - £75,000
3 year salary for senior post-doctoral scientist for project on population pharmacokinetics of cytotoxic drugs in breast cancer therapy
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Cancer Research Campaign - £200,000 per annum
Supervision of programme grant expenditure of CRC Pharmacology Group - 5 year programme Grant.
1992
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Scottish Hospital Endowments Research Trust - £50,000
2 year's salary for senior post-doctoral scientist for project on formulation of cytotoxic drugs for cerebral implantation in the treatment of brain tumours.
Grant Holders - D J Kerr, T A Whately, R Rampling, J Plumb
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Queen Elizabeth Endowment Trust - £42,000
Development of Inhibitors of P-Glycoprotein.
Grant Holders - D J Kerr, D R Ferry
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Queen Elizabeth Endowment Trust - £27,000
Interaction of Platinum with the HIV Promoter Sequence.
Grant Holders - D J Kerr, C J Poole, L Young
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Cancer Research Campaign - £500,000
Laboratory Refurbishment grant on joining University of Birmingham
Grant Holder – D J Kerr
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Cancer Research Campaign - £620,000
Molecular Pharmacology Group
Grant Holder – D J Kerr
-
Cancer Research Campaign - £1 million
Programme Grant Supporting Clinical Trials Unit
Grant Holder – D J Kerr
1994
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Regional Health Authority- £5 million
To house the expanding Institute for Cancer Studies
Grant holder - D J Kerr
September 1995-September 1999
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Medical Research Council £1,501,304
Gene Therapy of Common Cancers: Immunological & Pharmacological Approaches to Gynaecological Cancer.
Grant holders - LS Young, PF Searle, D. Luesley, AB Rickinson, PH. Gallimore
Departments Expenses-Core Funding 1995-1999
Grant holders - AB Rickinson and DJ Kerr
September 1994-September 1997
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Glaxo Research and Development Limited (plc) - £75,000
A Co-administration of rising oral GG918 Dose Levels with Doxorubicin Phase 1 Study
Grant holders - DJ Kerr
January 1995-January 1998
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M.L. Laboratories plc - £75,794
Adjuvant Intraperitoneal Chemotherapy with 5-fluorouracil in Duke’s Stage B and C Colic Adenocarcinoma (VICTOR)
Grant holder - DJ Kerr
November 1995-November 1997
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Special Trustees of the Former UBH Trust £49,233
Investigation of Phospholipase Signal Transduction Pathways in Human Breast Cancer
Grant holders - DJ Kerr and MJO Wakelam
March 1997-March 1998
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Takeda Chemical Industries Ltd. (Japan) £42,000
A Phase II Open Label Study to Determine the Safety Tolerability and Efficacy of CV6504(HCI) in Patients with pancreatic cancer
Grant holders - DJ Kerr
September 1996-September 1999
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Glaxo-Wellcome R and D £120,000
Immunological and Pharmacological Aspects of Gene Therapy
Grant holders - DJ Kerr
1996-2001
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Cancer Research Campaign £616,335
Core Clinical Fellowships
Grant holders - DJ Kerr
1997-2001
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Cancer Research Campaign £1,102,030
Clinical Trials Unit – Core Support
Grant holders - DJ Kerr
1995-1998
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Cancer Research Campaign £68,526
West Midlands Trials of Adjuvant Treatment in Early Breast Cancer
Grant holder - DJ Kerr
1998-2003
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Cancer Research Campaign £534,695
Pre-Clinical and Clinical Pharmacology and Macromolecular Drug Targeting
Grant holder - DJ Kerr
1998-2002
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Cancer Research Campaign £135,690
ATTOM UKCCCR Randomised Trial to Establish Optimum Length of Adjuvant Tamoxifen
Grant holder - DJ Kerr
1994-1997
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Ministry of Agriculture, Fisheries and Food £200,742
Evaluation of Non-Nutrient Dietary Constituents in Prevention of Breast Cancer
Grant holders - DJ Kerr, A Gescher, K. Chipman
1997
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The Higher Education Funding Council Capital £249,640
Research and Development for a Boron Cancer Therapy Clinical Facility
Grant holders - DJ Kerr, N James, D. Beynon
1996-2001
Foundation of a Regional Clinical Trials Unit
Grant holders - DJ Kerr, R Hobbs, L Ward, J Dunn, J Kenkre
1994-1999
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Medical Research Council £1.36 million
QUASAR Adjuvant Trial of Colorectal Cancer Chemotherapy
Grant holders - DJ Kerr and R Gray
1998
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Wellcome Trust £2.8 million
Construction of a clinical research facility
Grant holders – M Sheppard, P Stewart, DJ Kerr, M Wakelam, LS Young, AB Rickinson, C Savage
1998-2003
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Medical Research Council £403,608
Co-operative Group – Translational Research: Gene and Immunotherapy of Cancer.
Grant holders: DJ Kerr, DH Adams, PAH Moss, V Mautner, PF Searle, L Seymour and LS Young
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Medical Research Council £68,240
Joint Research Equipment Initiative Award
Grant Holders: P Moss, A Rickinson, D Kerr, J Gordon, L Young C Bunce
1997-2002
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Zeneca Pharmaceuticals £1,130,000
Clinical Trials Grant for Adjuvant Colorectal Cancer Trial: PETACC
-
Medical Research Council £600,000
FOCUS : trial of chemotherapy in advanced colorectal cancer
Grant Holders: M Seymour, R James, D J Kerr, T Maugham and R Stephens
Recently awarded grants
MERCK – Cancer Research Campaign £12.6 million – 2002 – 2009
Trial of adjuvant therapy with cyclooxygenase inhibitors in colorectal cancer
Grant Holder: D J Kerr
Roche/Aventis – Cancer Research Campaign £4 million – 2004 - 2009
Adjuvant trial of chemotherapy for colorectal cancer
Grant Holder: D J Kerr
Genomic Healthcare £83,330 - 2006-2008
Proteomic investigation of colorectal cancer
Grant holder: D J Kerr
NHS R & D £20 million - 2001 – 2006
To establish the National Translational Cancer Research Network (NTRAC) and the National Cancer Tissue Resource (NCTR).
Grant Holder: D J Kerr
E-Science Pilot Project in Integrative Biology - £ 1,244 310
Lead investigator: D Gavaghan
Co-investigator: D J Kerr
CRUK Gene Therapy Programme Grant - £1.2 million - 2004 - 2009
Lead investigator: L Seymour
Co-investigator: D J Kerr
Genomic and proteomic approaches to identify novel Markers of Colorectal Cancer, MRC Co-operative Grant:
£215,788 – 2004 -2007
Lead investigators: D J Kerr and I Tomlinson
GE Healthcare: Molecular Basis of Colorectal Cancer - £2.4 million – 2005-2007
Lead Investigator: D J Kerr
Cancer Research UK, Research Grant, ECMC Award - CRUK funding for the experimental cancer medicine centre - £3,070,410 - 2007 – 2012
Lead investigator: A Harris
Co-investigator: D J Kerr
EUROCAN: £80,421- 2005 – 2007
Lead investigator: P Boyle
Co-investigator: D J Kerr
SCOT Study ad adjuvant colorectal cancer chemotherapy: MRC £1,798,433 – 2006- 2014
Lead investigator: J Cassidy
Co-investigator: D J Kerr
Roche Ltd: £1.5 million – 2012 – current
Lead Investigator: DJ Kerr
Oxford Cancer Biomarkers: £3.25 million – 2011- current
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