Analysis of ex vivo drug response data of Plasmodium clinical isolates: the pros and cons of different computer programs and online platforms
In vitro drug susceptibility testing of malaria parasites remains an important component of surveillance for anti-malarial drug resistance. The half-maximal inhibition of growth (IC50) is the most commonly report...
Grennady Wirjanata, Irene Handayuni, Sophie G. Zaloumis, Ferryanto Chalfein, Pak Prayoga, Enny Kenangalem, Jeanne Rini Poespoprodjo, Rintis Noviyanti, Julie A. Simpson, Ric N. Price and Jutta Marfurt
Malaria Journal 2016 15:137
Predicting factors for malaria re-introduction: an applied model in an elimination setting to prevent malaria outbreaks
Malaria re-introduction is a challenge in elimination settings. To prevent re-introduction, receptivity, vulnerability, and health system capacity of foci should be monitored using appropriate tools. This stud...
Mansour Ranjbar, Alireza Shoghli, Goodarz Kolifarhood, Seyed Mehdi Tabatabaei, Morteza Amlashi and Mahdi Mohammadi
Malaria Journal 2016 15:138
Development of insulated isothermal PCR for rapid on-site malaria detection
Detection of Plasmodium spp. is sometimes inconvenient especially in rural areas that are distant from a laboratory. In this study a portable diagnostic test of Plasmodium spp. was developed using insulated isoth...
Kek Heng Chua, Ping Chin Lee and Hwa Chia Chai
Malaria Journal 2016 15:134
Operational challenges to continuous LLIN distribution: a qualitative rapid assessment in four countries
The World Health Organization recommends that long-lasting insecticidal nets (LLINs) for malaria prevention should be distributed continuously through antenatal care (ANC) and the expanded programme on immuniz...
Katherine Theiss-Nyland, Waqo Ejersa, Corine Karema, Diakalia Koné, Hannah Koenker, Yves Cyaka, Matthew Lynch, Jayne Webster and Jo Lines
Malaria Journal 2016 15:131
Reactive case-detection of malaria in Pailin Province, Western Cambodia: lessons from a year-long evaluation in a pre-elimination setting
As momentum towards malaria elimination grows, strategies are being developed for scale-up in elimination settings. One prominent strategy, reactive case detection (RACD), involves screening and treating indiv...
John Hustedt, Sara E. Canavati, Chandary Rang, Ruth A. Ashton, Nimol Khim, Laura Berne, Saorin Kim, Siv Sovannaroth, Po Ly, Didier Ménard, Jonathan Cox, Sylvia Meek and Arantxa Roca-Feltrer
Malaria Journal 2016 15:132
Multi-year optimization of malaria intervention: a mathematical model
Malaria is a mosquito-borne, lethal disease that affects millions and kills hundreds of thousands of people each year, mostly children. There is an increasing need for models of malaria control. In this paper,...
Harry J. Dudley, Abhishek Goenka, Cesar J. Orellana and Susan E. Martonosi
Malaria Journal 2016 15:133
Entomological aspects and the role of human behaviour in malaria transmission in a highland region of the Republic of Yemen
The Republic of Yemen has the highest incidence of malaria in the Arabian Peninsula, yet little is known of its vectors or transmission dynamics.
Samira M. A. Al-Eryani, Louise Kelly-Hope, Ralph E. Harbach, Andrew G. Briscoe, Guy Barnish, Ahmed Azazy and Philip J. McCall
Malaria Journal 2016 15:130
Spatially aggregated clusters and scattered smaller loci of elevated malaria vector density and human infection prevalence in urban Dar es Salaam, Tanzania
Malaria transmission, primarily mediated by Anopheles gambiae, persists in Dar es Salaam (DSM) despite high coverage with bed nets, mosquito-proofed housing and larviciding. New or improved vector control strateg...
Victoria M. Mwakalinga, Benn K. D. Sartorius, Yeromin P. Mlacha, Daniel F. Msellemu, Alex J. Limwagu, Zawadi D. Mageni, John M. Paliga, Nicodem J. Govella, Maureen Coetzee, Gerry F. Killeen and Stefan Dongus
Malaria Journal 2016 15:135
Population pharmacokinetics of a three-day chloroquine treatment in patients with Plasmodium vivax infection on the Thai-Myanmar border
A three-day course of chloroquine remains a standard treatment of Plasmodium vivax infection in Thailand with satisfactory clinical efficacy and tolerability although a continuous decline in in vitro parasite sen...
Richard Höglund, Younis Moussavi, Ronnatrai Ruengweerayut, Anurak Cheomung, Angela Äbelö and Kesara Na-Bangchang
Malaria Journal 2016 15:129
Bed net use among school-aged children after a universal bed net campaign in Malawi
Recent data from Malawi suggest that school-aged children (SAC), aged 5–15 years, have the highest prevalence of Plasmodium falciparum infection among all age groups. They are the least likely group to utilize in...
Andrea G. Buchwald, Jenny A. Walldorf, Lauren M. Cohee, Jenna E. Coalson, Nelson Chimbiya, Andy Bauleni, Kondwani Nkanaunena, Andrew Ngwira, Atupele Kapito-Tembo, Don P. Mathanga, Terrie E. Taylor and Miriam K. Laufer
Malaria Journal 2016 15:127
Human malaria diagnosis using a single-step direct-PCR based on the Plasmodium cytochrome oxidase III gene
Nested PCRs based on the Plasmodium 18s-rRNA gene have been extensively used for human malaria diagnosis. However, they are not practical when large quantities of samples need to be processed, further there have ...
Diego F. Echeverry, Nicholas A. Deason, Jenna Davidson, Victoria Makuru, Honglin Xiao, Julie Niedbalski, Marcia Kern, Tanya L. Russell, Thomas R. Burkot, Frank H. Collins and Neil F. Lobo
Malaria Journal 2016 15:128
Challenges with implementing malaria rapid diagnostic tests at primary care facilities in a Ghanaian district: a qualitative study
Rapid diagnostic Tests (RDTs) for malaria enable diagnostic testing at primary care facilities in resource-limited settings, where weak infrastructure limits the use of microscopy. In 2010, Ghana adopted a tes...
Nana Yaa Boadu, John Amuasi, Daniel Ansong, Edna Einsiedel, Devidas Menon and Stephanie K. Yanow
Malaria Journal 2016 15:126
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