Introduction to Human General Embryology Developmental Genetics


What is the outcome of fertilization?



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Summary Notes in Gen Embryology
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What is the outcome of fertilization?

  1. Resumption and completion of the second meiotic division and release of the second polar body.

  2. Development of the Zygote

  3. Restoration of the diploid number of chromosome

  4. Determination of sex

  5. Induction of Cleavage

  6. A factor of human variation



NB:

Infertility

The inability in individuals to achieve fertilization is termed Infertility.


Women with repeated miscarriages are also classified as Infertility.




Infertility in Females
In order for a woman to become pregnant:

i. Egg must be released from one of her ovaries (ovulation)


ii. Egg must go through the fallopian tube toward the uterus
iii. Sperm must join with the egg in the fallopian tube (fertilization).
iv. Fertilized egg must attach to the uterine wall (implantation)

Therefore, infertility can result from problems that interfere with any of these steps listed above.


The risk factors of infertility include age, stress, poor diet, smoking, alcohol, sexually transmitted disease, overweight, underweight, caffeine intake, and too much exercise.


Factors influencing infertility in females include:





  1. Severe endometriosis

  2. Pelvic Inflammatory Disease (PID)

  3. Ovulation disorders

  4. Elevated prolactin

  5. Polycystic ovary syndrome (PCOS)

  6. Early menopause

  7. Benign uterine fibroids

  8. Pelvic adhesions



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Physical Obstructions




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