Introductory Manual 2008-2009 Table of Contents


*Economics 980q. Economics Design Lab



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*Economics 980q. Economics Design Lab [Fall, Th., 2:30-4:30]

Sendhil Mullainathan

This class offers a chance for students to see how social science insights (economics, finance and psychology) can be used to design policies and products that solve important problems. Presents examples of innovative designs. Applications are in areas such as maternal mortality, development of drugs for diseases faced mainly by the poor, financing small firms, unemployment insurance, prescription drug insurance to the elderly and fighting corruption in important social programs.



Note: Each student will be asked to pick one concrete problem and craft a solution. Students with non-traditional economic backgrounds (such as psychology or engineering) are particularly encouraged to take the course.
Economics 1393. Poverty and Development [Spring, M., W., 1-2:30]

Nathan J. Nunn

Studies the relationship between economic growth, poverty, and income distribution. Discusses how globalization affects poverty and inequality. Studies the main theories of economic growth and the main potential sources of economic development, from physical capital accumulation, to education, to technology, to the role of government. Discusses various global issues such as public global health (e.g., the impact of malaria and AIDS on Africa), corruption and institutions, natural resources, the environment, international donor institutions, and population growth.



Prerequisite: Economics 1010a (or 1011a) and 1010b (or 1011b).
*Environmental Science and Public Policy 90f. Global Change and Human Health [Spring, Tu., 1-3:30]

James J. McCarthy and Paul R. Epstein

Global consequences of increasing human population and our consumption of natural resources include extensive changes in many natural ecosystems and in the composition of Earth's atmosphere. In the last decade, geographic ranges of certain well known infectious diseases have expanded and new diseases have become threats to human health. This seminar explores hypothesized linkages between changes in ecosystems, climate, and the epidemiology of certain infectious diseases.


*Extra-Departmental Courses 187. The Quality of Health Care in America [Spring, Tu., Th., 4:30-6, and a weekly section to be arranged]

Donald M. Berwick (Public Health, Medical School), David Blumenthal (Medical School), Howard H. Hiatt (Medical School, Public Health), and Warner V. Slack (Medical School)

Offers information and experiences regarding most important issues and challenges in health care quality. Overview of the dimensions of quality of care, including outcomes, overuse, underuse, variation in practice patterns, errors and threats to patient safety, service flaws, and forms of waste. Each session focuses on one specific issue, exploring patterns of performance, data sources, costs, causes, and remedies. Explores desirable properties of health care systems that perform at high levels in many dimensions of quality.


*Freshman Seminar 25g. The Impact of Infectious Diseases on History and Society [Fall, Th., 7-9 p.m.]

Donald A. Goldmann

Mankind's journey- farming, urbanization, exploration, trade, globalization -has been marked by devastating encounters with infectious diseases. Infections have affected wars, political dynasties, global balance of power, social structure, public health policy, economics, and the arts. This course explores these themes by studying infections such as plague, syphilis, smallpox, malaria, sleeping sickness, tuberculosis, cholera, yellow fever, polio, and influenza. It investigates how the epidemiology of these diseases, and society's response, inform contemporary policy and future threats.



Note: Open to Freshmen only.
*Freshman Seminar 25t. AIDS in Africa [Spring, Hours to be arranged]

Myron Essex (Public Health) and Tun-Hou Lee (Public Health)

HIV/AIDS has infected or killed more than sixty million people, and no vaccine is expected within five to ten years. About two-thirds of current infections are in ten percent of the world's population in sub-Saharan Africa, where few patients receive life-saving treatment. Explores dimensions of AIDS in Africa including the evolution and epidemiology of HIV, the pathobiology of AIDS, prevention of infection, and treatment of disease. Encourages multidisciplinary approaches, using country-specific illustrations of successful interventions.



Note: Open to Freshmen only.
Government 1093. Ethics, Biotechnology, and the Future of Human Nature [Spring, M., 2-4]

Michael J. Sandel and Douglas A. Melton

Explores the moral, political, and scientific implications of new developments in biotechnology. Does science give us the power to alter human nature? If so, how should we exercise this power? The course examines the science and ethics of stem cell research, human cloning, sex selection, genetic engineering, eugenics, genetic discrimination, and human-animal hybrids.



Note: May not be taken concurrently with MCB 60. May not be taken for credit if MCB 60 has already been taken. Moral Reasoning 22 (Justice) is recommended as background. Enrollment may be limited.
[Government 1100. Political Economy of Development] [Fall, Hours to be arranged]

Robert H. Bates

Comparative analysis of political economy of development drawing on case studies from Africa, Asia, the Middle East, and Latin America.


Government 1197. The Political Economy of Africa [Spring, Hours to be arranged]

James Robinson

The basic social science literature on Africa's development. Particular emphasis on political economy.


*History 87a. Health, Disease, and Ecology in African History [Spring, W., 2-4]

Emmanuel K. Akyeampong

Examines the history of disease and health in sub-Saharan Africa from the 19th century to recent times, exploring African and western concepts of health, disease and healing. Illustration through discussion of case studies of individual diseases, including malaria/sickle cell trait, trypanosomiasis, tuberculosis, sexually transmitted diseases, alcoholism, AIDS, and onchocerciasis, and the public health policies affecting them.



Prerequisite: Senior level undergraduates.
History of Science 140. Disease and Society [Fall, M., W., (F.), at 12]

Charles E. Rosenberg

A consideration of changing conceptions of disease during the past two centuries. We will discuss general intellectual trends as well as relevant cultural and institutional variables by focusing in good measure on case studies of particular ills, ranging from cholera to sickle cell anemia to anorexia and alcoholism.


History of Science 141. The Social Life of Pharmaceuticals (New Course) [Fall, W., 2-4]

Jeremy Alan Greene

The evolution of the modern pharmaceutical industry over the long twentieth century--from its early intersection with the image and later the structure of scientific research, to its dramatic post-WWII expansion and late-century saturation of medical and marketing media--is tightly intertwined with broader social, cultural, economic, and political developments. This conference course engages primary and secondary works in the history and anthropology of pharmaceuticals to situation the prescription drug as cultural artifact.


*History of Science 154. Science and Business in Modern America [Spring, M., 2-4]

Steven Shapin

A survey of the relationships between the practice of science and the world of commerce in the United States since the beginning of the 20th century. Topics covered include the conduct and image of science in academia and industry, ideas about the connections between science and technology, and the development and understanding of entrepreneurial science.


History of Science 159v. Science and Society (New Course) [Fall, Tu., Th., at 12]

Andrew Lakoff

In such fields as health, the environment, and law, we rely on scientific expertise to help us distinguish truth from lie, to measure risk, to treat our ills. In this context, it is crucial to know how such knowledge is produced, disseminated, and arbitrated. This course focuses on areas of controversy such as genetically modified foods, intellectual property, global warming, and new reproductive technologies in order to understand the complex relationship between science and society.


History of Science 160. Intellectual Property in Science [Spring, Tu., 2-4]

Mario Biagioli

We examine different forms of credit for scientific and technological innovation, comparing publication credit in science and use of patents to protect technoscientific work. Readings range from history of technoscience to legal and literary studies.


Life Sciences 1a. An Integrated Introduction to the Life Sciences: Chemistry, Molecular Biology, and Cell Biology [Fall, Tu., Th., 1-2:30]

Erin K. O'Shea, Daniel E. Kahne, and Robert A. Lue

What are the fundamental features of living systems? What are the molecules imparting these features, and how do their chemical properties explain their biological roles? The answers form a basis for understanding the molecules of life, the cell, diseases, and medicines. In contrast with traditional presentations of relevant scientific disciplines in separate courses, we take an integrated apprach, presenting chemistry, molecular biology, biochemistry, and cell biology framed within central problems such as the biology of HIV and cancer.



Note: This course, in combination with Life Sciences 1b, constitutes an integrated introduction to the Life Sciences. When taken for a letter grade, Life Sciences 1a meets the Core area requirement for Science A. This course, when taken for a letter grade, meets the General Education requirement in Science of Living Systems.
Life Sciences 60. Ethics, Biotechnology, and the Future of Human Nature [Spring, M., 2-4]

Douglas A. Melton and Michael J. Sandel

Explores the moral, political, and scientific implications of new developments in biotechnology. Does science give us the power to alter human nature? If so, how should we exercise this power? The course examines the science and ethics of stem cell research, human cloning, sex selection, genetic engineering, eugenics, genetic discrimination, and human-animal hybrids. Readings will be drawn from literature in the areas of biology, philosophy, and public policy.



Note: May not be taken concurrently with Government 1093. May not be taken for credit if Government 1093 has already been taken. The course is open to both science and non-science concentrators. Moral Reasoning 22 is recommended as a background. Enrollment may be limited.
MCB 192. Principles of Drug Discovery and Development [Spring, Tu., Th., 11:30-1]

Vicki L. Sato and Mark C. Fishman (Medical School)

This interdisciplinary course will examine the process of drug discovery and development through disease-driven examples. Topics include: the efficacy/toxicity balance, the differences between drugs and inhibitors, the translation of cellular biochemistry to useful medicine.



Note: May not be taken concurrently with Chemistry 192. May not be taken for credit if Chemistry 192 has already been taken.

Prerequisite: MCB 52 and one year of organic chemistry. MCB 54 is recommended.
MCB 234. Cellular Metabolism and Human Disease [Spring, M., W., F., 9-10:30]

Thomas Michel (Medical School), Robert A. Lue and members of the Department

Half course (spring term)

Cellular and organismal metabolism, with focus on interrelationships between key metabolic pathways and human disease states. Genetic and acquired metabolic diseases and functional consequences for specific organ systems. Lectures and conferences are integrated with clinical encounters with patients.



Note: Students may attend lectures in either Cambridge or Boston since they will be transmitted live from HMS to Harvard College and vice-versa; the inter-campus link will allow real-time interactions between students and faculty at each site. May not be taken concurrently with BCMP 234. May not be taken for credit if BCMP 234 has already been taken.

Prerequisite: Knowledge of introductory biochemistry, genetics, and cell biology required (MCB 52 and MCB 54 or equivalent); one year of organic chemistry.
Quantitative Reasoning 50. Medical Detectives [Fall, M., W., F., at 9]

Karin B. Michels (Medical School, Public Health)

Why is there confusion in the scientific community as to whether butter or margarine is worse for your health? How do epidemiologists find out whether cell phone use increases your risk for brain cancer? What is your risk of contracting diabetes? Discover how researchers draw on quantitative skills to detect causes of acute disease outbreaks and chronic diseases. This course introduces the techniques and methods for empirically based analyses, decisions, and actions in the context of current public health problems.


Science of Living Systems 11. Molecules of Life [Fall, Tu., Th., 10-11:30]

Jon Clardy (Medical School) and David R. Liu

Large molecules - DNA, RNA, and proteins - encode and transmit the inherited information in our genes. This course focuses instead on the small molecules that link the genetic program in our DNA to the world in which we live. Small molecules govern how our bodies develop, allow us to respond to changes in our environment, and carry our thoughts. They are also the basis of the drugs we use to fight infections and combat diseases including cancer, diabetes, and depression. In the future, small molecules could even be used to direct the fate of stem cells or extend life.



Note: This course, when taken for a letter grade, meets the Core area requirement for Science B.
Sociology 165. Inequalities in Health Care [Fall, M., W., (F.), at 3]

Mary Ruggie (Kennedy School)

Asks why certain social groups are at greater risk for more severe health problems (eg., infant mortality, HIV/AIDS, cancer) and yet receive unequal health care in the US. Examines selected health disparities around the world and what best practices foster adequate delivery of healthcare services, mutual respect between patient and provider, and healthy living.


Studies of Women, Gender, and Sexuality 1177. AIDS: Politics, Culture, and Science [Spring, M., W., at 11]

Ian Keith Lekus

This course introduces the political, social, cultural, and medical constructions of the HIV/AIDS pandemic. Drawing upon diverse interdisciplinary texts, we will investigate the pandemic's historical epidemiology; state, medical, and grassroots responses to AIDS; and evolving media representations of AIDS. We will explore both continuities and changes in these dynamics from local, national, and transnational perspectives. To do so, we will focus on examples from the U.S., Latin America, sub-Saharan Africa, and South Asia.


[Social Analysis 28. Culture, Illness, and Healing: An Introduction to Medical Anthropology] [Expected to be given in 2009-2010, Spring, Tu., Th., at 10]

Arthur Kleinman

An inquiry into the role of health and medicine in society that demonstrates how anthropological analysis can be applied to the study of illness and care. Compares medical systems across societies to understand the experience and treatment of sickness. Analyzes how practitioners and patients construe sickness and suffering as distinctive social realities, and how those realities are organized in local cultural systems. Assesses varieties of suffering as social phenomena in order to appreciate the social sources of global social problems, the cross-cultural variety of illness experiences, the reform of services, and the global moral and political-economic crisis in health care.


[Social Analysis 76. Global Health Challenges] [Expected to be given in 2009-2010, Fall, M., W., (F.), at 10]

Sue J. Goldie (Public Health, Medical School)

This course introduces the principal health problems of the world's populations. It is an inter-disciplinary exploration of the factors that account for health patterns, ranging from their physiological basis to their epidemiological, economic, social and political context. Topics include: infectious and chronic diseases, childhood and reproductive health, aging, health systems, priority setting, and real world policy. Emphasis is placed on methods for measuring population health, the evidence base for the costs and consequences of interventions, and analytic tools for decision making. Students are encouraged to think creatively about the major challenges to improving health at a global level.



Sociology 190. Life and Death in the US: Medicine and Disease in Social Context [Spring, M., W., at 3]

Nicholas A. Christakis (Medical School, FAS)

Explores how biological and social factors jointly conspire to determine the health of individuals and populations. Examines how medical care, social networks, and socioeconomic inequality influence illness, recovery, and death.



Note: This course, when taken for a letter grade, meets the Core requirement for Social Analysis.
Studies of Women, Gender, and Sexuality 1177. AIDS: Politics, Culture, and Science [Spring, M., W., at 11 ]

Ian Keith Lekus

This course introduces the political, social, cultural, and medical constructions of the HIV/AIDS pandemic. Drawing upon diverse interdisciplinary texts, we will investigate the pandemic's historical epidemiology; state, medical, and grassroots responses to AIDS; and evolving media representations of AIDS. We will explore both continuities and changes in these dynamics from local, national, and transnational perspectives. To do so, we will focus on examples from the U.S., Latin America, sub-Saharan Africa, and South Asia.



Appendix: HCGHAC Constitution
The Constitution of the Harvard College Global Health and AIDS Coalition
Preamble

We the members of the Harvard College Global Health and AIDS Coalition, in order to promote a strong, lasting commitment to the ideals of social justice, organize effective initiatives combating global health inequity, and fight for health as a basic human right, do hereby establish this Constitution of the Harvard College Global Health and AIDS Coalition (HCGHAC).


Article I. Mission

The Harvard College Global Health and AIDS Coalition (HCGHAC) believes that health should be a fundamental human right.


Towards this end, HCGHAC strives to challenge and expand the role of both the university and individual students in addressing global health and development needs.
Through collaboration with various parties, HCGHAC aims to:

-Engage students in a growing movement for global health through education and awareness activities

-Effect policy change through advocacy and activism, both on and off campus

-Address local and global health needs through direct service and fundraising


Through these initiatives, HCGHAC strives to build momentum for a social movement that seeks social justice, especially in pursuing health as a human right. HCGHAC hopes this movement will instill a lasting commitment to global health among members of the Harvard community, and empower these current and future leaders to carry out this commitment in their personal and professional lives.
Article II. HCGHAC General Membership and Membership Rights

Membership in HCGHAC is conferred upon individuals who have attended at least two general2 meetings in the last calendar year. Every member has the right to



  1. Ask for an evaluation of any initiative decision by the general HCGHAC body

  2. Request a report about any general or initiative decision, action, or other proceeding

  3. Propose a new initiative

  4. Join any existing initiative

  5. Participate in any decision-making dialogue and all general voting procedures


Article III. Initiatives

Initiatives are action groups, comprised of HCGHAC members, whose purpose is to carry out all or part of HCGHAC’s mission through defined goals.


Any member may propose an initiative. Initiative proposals must be submitted on the Sunday planning meeting prior to the initiative’s approval in a general meeting. Approval for new initiatives will be granted in general meetings by consensus, in order to ensure that initiatives are wedded to HCGHAC’s mission and accountable to its general membership.

Each initiative, upon formation, will design a format and be held responsible for the work of logistics coordinator(s).

The duties of the logistics coordinator are as follows:


  1. Organize weekly meeting time

  2. Communicate weekly meeting time to HCGHAC member email list with at least 48 hours notice

  3. Send weekly update to HCGHAC discussion email list by Sunday at noon.

Format for designating logistics coordinator may be revised at any point by consensus among initiative members, and will be revisited by each initiative at yearly fall retreat.
Article IV. Bureaucracy

The Bureaucracy of HCGHAC will be held accountable by the general membership for the following:



  1. Accounting of finances and management of budget

  2. Collection and dissemination of meeting notes

  3. Room booking for general and introductory meetings as well as yearly fall retreat

  4. Yearly Re-Registration and attendance at University affiliate meetings

  5. Moderate and add new members on relevant email lists

  6. Ensure website maintenance

  7. Maintain a current membership roster

  8. Follow up on initiative deliverables

  9. Ensure continuation of teach-in and speaker series initiatives

  10. Act as liaison to outside groups or individuals for non-initiative-specific endeavors

  11. Ensuring regular social events for HCGHAC membership

  12. Support recruitment of new members and facilitate their entrance into initiatives

  13. Facilitate and support information transfer

  14. Organize weekly rotating chair for planning and general meetings

Terms of membership to the Bureaucracy will last for twelve months, commencing upon the first day of the Spring academic semester. The Bureaucracy must have no fewer than three members.


Individuals must have been members of HCGHAC for a minimum of two semesters to be eligible for the Bureaucracy. Members must declare their candidacy for the Bureaucracy by submitting a statement to HCGHAC general email list no later than one week prior to confirmation vote.
Membership to the Bureaucracy must be confirmed by the membership of HCGHAC. A minimum of 15 members must be present in order for confirmation voting to be valid. All candidates must be present at a question-and-answer session, of no less than 10 minutes, prior to confirmation voting. Each member can vote to either approve or not approve each candidate. Voting will be anonymous. Candidates must earn 3⁄4 approving votes of all votes cast to be confirmed as an acting member of the Bureaucracy. Graduating seniors will preside over voting procedures and vote counting, including the administration of absentee voting. This body of seniors will also be responsible for organizing and communicating the voting time with at least two weeks’ notice to HCGHAC members via the general email list.
Any member may motion for a vote of no confidence on a member of the Bureaucracy at any time. In order to move into voting procedures, a quorum of 12 HCGHAC members must be reached. Motion must be approved by a ¾ majority of all votes cast. If the motion to proceed with a vote of no confidence is approved, the vote will take place at the following general meeting. Members of the Bureaucracy will be responsible for notifying HCGHAC members via general email list that a vote of no confidence will be held. A 15 member quorum is required for a vote of no confidence to take place. A ¾ majority must vote “no confidence” in order for the Bureaucracy member in question to be removed from the Bureaucracy.
In the event that the Bureaucracy consists of less than the minimum 3 members at any given point, the Bureaucracy must call for emergency elections to install additional Bureaucracy member(s) for the remainder of the current term.
Article V. Planning Meetings

Weekly planning meetings serve as a forum for idea generation and logistical preparation for the weekly general meetings. All initiatives that seek presentation time on the general meeting agenda must have a representative present at the planning meeting.


Planning meetings will be facilitated by the weekly rotating chair.
Weekly written initiative updates must be made available to HCGHAC discussion email list by Sunday at noon. Bureaucracy members will follow up on initiatives that do not submit weekly updates.
Members of the Bureaucracy are required to attend planning meetings. All other HCGHAC members are encouraged to attend.
Article VI. General Meetings

General meetings serve as the governance forum for all procedural and substantive HCGHAC concerns, including discussion, deliberation, and knowledge reproduction. General meetings should involve clever introductions, initiative updates and involvement opportunities, group decisions, and discussion of new ideas and initiatives.


General meetings will be facilitated by the rotating weekly chair, whose duties are to:

  1. Attend, facilitate, and take notes at the prior planning meeting

  2. Email an agenda informed by the proceedings at the weekly planning meeting to the HCGHAC general email list no less than 24 hours before the general meeting.

  3. Moderate general meeting discussion, motions to vote, and voting procedures. Any member has the right to motion for a substitute voting facilitator for any particular issue. This motion must be approved by a ¾ majority for alternate voting facilitator to be selected, and the new voting facilitator must be approved by a ¾ majority.

  4. Designate and follow up with a note-taker, whose duty it is to take notes on the meeting discussion and email said notes to the HCGHAC general email list, chosen for the meeting’s duration.

All major and/or non-initiative-specific decisions will be determined by a general meeting vote. The objective of general meeting discussions will be to reach unanimous consent.


In order for a group decision to be reached, a quorum of ten voting members in the general meeting must be reached.
At any point, any member can motion to vote to determine consensus.
All votes may be made by acclamation (hand-raising) or anonymous vote. Voting proceedings will be coordinated and votes counted by the meeting chair. It is expected that members who were not present for the discussion period preceding voting procedures will abstain.
After 10 minutes any member can motion to vote via ¾ majority. 2/3 majority consent is required to proceed with ¾ majority vote.
If ¾ majority cannot be reached by the end of the session, any member can motion for a simple majority vote at the following general meeting. Simple majority consent is required to proceed with simple majority vote. At the following meeting, any member can motion for a fifteen minute period of discussion before voting takes place.

After a decision has been made, any member may make a motion to vote by 2/3 majority to reopen discussion on the topic.


Article VII. Constitutional Amendment Procedures

Any member has the right to propose an amendment.


An amendment proposal must be made available over the general member email list at least one week prior to the general meeting at which voting will occur.
In order to move to vote on an amendment, a quorum of twelve voting members in the general meeting must be reached. Any member can motion to vote on an amendment, a 2/3 majority must approve the motion for an amendment vote for the vote to be held. A 2/3 majority of all votes cast is required for an amendment to pass, at which point the amendment will become active.

Bureaucracy Members 2008

Neha Gupta

Jean Junior

Heidi Kim

Sarah Ruberman

Molly Siegel



Jon Weigel

1 B. Aronson, “Improving Online Access to Medical Information for Low-income Countries,” New England Journal of Medicine 350 (2004): pp. 966–968.

2 “General” as used throughout the document denotes the full HCGHAC membership, and/or those issues which concern all members. General decisions are those reached by consensus or voting procedures at general meetings.



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