Introductory Manual 2008-2009 Table of Contents



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Part 1: Terms and People
NAVIGATING HARVARD
FAS: Faculty of Arts and Sciences. Where Harvard College and GSAS (Graduate School of Arts and Sciences) are located.

HMS: Harvard Medical School.

HBS: Harvard Business School.

HLS: Harvard Law School.

HSPH: Harvard School of Public Health.

KSG: Kennedy School of Government.



TERMS AND ACRONYMS
3x5: The goal of the WHO was to treat 3 million people by 2005. Though they fell short of their goal, it was the largest jump in the number of people treated at the time.
Abbott: Pharmaceutical company, owner of the rights of the antiretroviral Kaletra.
ABC: Campaign for prevention of HIV/AIDS implemented in a variety of disease-burdened societies. Stands for Abstain, Be faithful, Condoms.
ACT, Artemisinin: This is a drug used to treat multi-drug resistant forms of malaria. ACT stands for artemisinin-based combination therapy.
ACT UP: AIDS Coalition to Unleash Power. Original AIDS activists that started the movement for HIV/AIDS awareness and action in San Francisco. Larry Kramer played a large part in this movement.
ARV: Antiretroviral drug.
ART: Antiretroviral Therapy, the general term for HIV/AIDS treatment.
Birddogging: When hunters go out hunting for quail, especially in overpopulated areas, they typically bring a “birddog” with them, which points the hunter to the game and fetches it once it has been killed. Similarly, birddogging is a political activity in which we engage. It involves going to political candidates’ events and asking them questions to point them towards adopting global health platforms.
BLC: The Boston Living Center is a non-profit community and resource center whose mission is to foster the wellness of all HIV positive people and respond to the changing needs of the HIV/AIDS community. The BLC provides education, treatment information, and support services to its members free-of-charge.

CDC: Center for Disease Control.
CHAI: The Clinton HIV/AIDS Initiative was established in 2002 to close the gap in access to ART by negotiating lower prices and by working with governments to improve the national health care systems required to deliver crucial medicines.
CHW: Community Health Worker. These health workers typically work within villages and resource poor areas of urban environments and serve to make sure that patients are adhering to prescribed drug regimens and are seeing doctors when needed. Many organizations and public entities have adopted varying models of community health work.
D4T: An antiretroviral drug that was originally developed by researchers at Yale, it was licensed to GlaxoSmithKlein and was largely unaffordable to those most affected by HIV/AIDS in sub-Saharan Africa. This drug was the target of a student-led campaign at Yale to allow for generic production in developing countries.
DOT: Directly Observed Therapy. In resource-poor settings, drug adherence is often a challenge. Sporadic drug use can lead to drug resistant forms of disease, which are particularly costly to treat. Directly observed therapy for HIV/AIDS and Tuberculosis typically involve community health workers who monitor drug adherence and make sure that patients are taking their drugs on time and seeing professional health workers regularly.
EAC: The Environmental Action Committee, a student group here at Harvard that tried to target Harvard University to reduce its share of greenhouse gasses and be climate neutral. They petitioned President Faust to enact policies at Harvard, which is particularly relevant for our own model. Over the summer Faust set targets to reduce greenhouse gas emissions to 30% below the levels of 2006 by 2016. As of now, EAC will be serving as a watchdog organization to make sure these pledges are fulfilled.
FXB: François Xavier Bagnoud Center for Health and Human Rights (at HSPH). Directed by Jim Kim.

Gates Foundation: A foundation founded by Bill and Melinda Gates, this is the largest private philanthropic organization that funds a variety of global health research initiatives.
GHD: Global Health Delivery. Project chaired by Professors Jim Kim (HMS/HSPH), Paul Farmer (HMS/HSPH), and Michael Porter (HBS), focusing on implementation of global health solutions.

GID: Global Infectious Diseases, a working group that is part of the Harvard Initiative for Global Health. The leaders of this group are Bruce Walker (HIV/AIDS researcher at HMS) and Dyann Wirth (Malaria researcher at HSPH).
Global Fund to fight AIDS, Tuberculosis, and Malaria: A branch of the United Nations to address HIV/AIDS, Malaria, and Tuberculosis in developing countries. Operates on a budget of approximately $11.6 billion USD and operates in 136 countries.
HAART: Highly Active Antiretroviral Therapy for HIV. This is a course of drug treatment that attempts to overcome drug resistance of HIV. It typically involves a cocktail of three drugs from different classes to reduce the viral load in patients.
HealthGAP: A grassroots political advocacy organization that aims to 1) propose legislation to address health disparities by persuading key political leaders to support their proposals and 2) effect change to already existing health policies in order to realize health as a human right.
HIGH: Harvard Initiative for Global Health is the body we are trying to scale-up with our Missing Medicines project. It currently focuses on global health education by hosting speaker events and assisting students in securing internships, fellowships, and grants.

HUGH Forum: Harvard University Global Health Forum is a Harvard group formed last year with interests eerily similar to HACs. According to its administrators, HUGH differs from HAC in that its main focus is on awareness, whereas HAC’s is on action.
ID: Infectious Disease.
IMF: International Monetary Fund.
Merck: A pharmaceutical company.
MGH: Massachusetts General Hospital.

MSF: Doctors Without Borders/Médecins Sans Frontières is an international medical humanitarian organization working in nearly 60 countries to bring medical care to people threatened by violence, neglect, or catastrophe. In 1999, MSF received the Nobel Peace Prize.

ND: Neglected Diseases.

NGO: Non-Governmental Organization.
NIH: National Institute of Health, it’s part of the US Department of Health and Human Services, and is the primary arm through which the US government funds health research. It conducts both “in-house” research and distributes federal grants.
Novartis: A pharmaceutical company, has a Boston branch.
One world health: A non-profit pharmaceutical company that engages in socially responsible research. A recipient of large Gates funds.
OTD: The TTO at Harvard. See TTO entry.
PDP: PPP Development Partnerships are a class of PPPs that focus on health product development for diseases of the developing world. PDPs have formed over the past decade to unite the public sector's commitment to international public goods for health with private industry's expertise in product development and marketing. These not-for-profit organizations bridge public- and private-sector interests, with a view toward resolving the specific incentive and financial barriers to increased industry involvement in the development of safe and effective products.

PEPFAR: The President's Emergency Plan For AIDS Relief was a commitment of $15 billion over five years (2003–2008) from Bush to fight the global HIV/AIDS pandemic -- the largest international health initiative ever initiated by one nation to address a single disease. In 2008 PEPFAR was reauthorized and expanded, totaling a commitment of $48 billion over five years

PIH: Partners In Health is an international organization that supports a range of health programs in poor communities in Haiti, Peru, Russia, Rwanda, and the United States. PIH also undertakes research and advocacy activities on behalf of the world’s sick and impoverished in the name of social justice.
PMTCT: Prevent Mother to Child Transmission (of HIV/AIDS). About 15-30% of infants born to HIV positive women acquire HIV during labor, and another 5-20% acquire HIV during breastfeeding. The simplest way to prevent mother to child transmission is a single dose of nevirapine, an antiretroviral drug that is given to the mother during labor and the child after delivery. This decreases the rate of transmission by roughly 50%.

PPP: Public-private partnership describes a government service or private business venture which is funded and operated through a partnership of government and one or more private sector companies.

SGAC: Student Global AIDS Campaign is a US-based network of over eighty-five student and youth organizations committed to the global fight against AIDS. It was founded in 2001 by Harvard Students as the Harvard AIDS Coalition (holla!) along with its parent organization, Global Justice.
TB: Tuberculosis.
TTO: Technology transfer office. This is the office at Harvard (and other institutions) that serves as an intermediary between science researchers who have developed innovative products and private companies looking to purchase the rights and intellectual property from university researchers.

Wellcome Trust: The Wellcome Trust spends over £600 million every year both in the UK and internationally achieving their mission: supporting and promoting research to improve the health of humans and animals.

WHO: World Health Organization.
UAEM: Universities Allied for Essential Medicines.

WHO’S WHO IN GLOBAL HEALTH?
Barry Bloom: Former dean of HSPH.
Jon Clardy: A Professor at Harvard Medical School, he is a basic science researcher who studies malaria, trypanosomiasis, and tuberculosis.
David Cutler: A Professor of Economics in the department of economics and Kennedy School of Government, and Associate Dean for Social Sciences, Faculty of Arts and Sciences for Social Sciences.

Opehlia Dahl: Executive director of Partners in Health. Granddaughter of Roald Dahl. Global Health activist.
Arnold Epstein: Professor of Health Policy and Management in the Department of Health Policy and Management at HSPH. Dr. Epstein's research interests focus on access and quality of care especially for disadvantaged populations.
Paul Farmer: A medical anthropologist and physician who has dedicated his life to treating the poor, while in the process helping to raise the standard of health care in underdeveloped areas of the world. He is the founding director of PIH. He is a Professor of Social Medicine at HMS.
Drew Faust: President of Harvard University, Faust has access to a large amount of money that she can use at her discretion. She oversees all of the schools at Harvard. We are working to get her support on global health funding here at Harvard.
Julio Frenk: An eminent authority on global health who served as the Minister of Health of Mexico from 2000 to 2006. He will become the new dean of HSPH in January 2009.
Sue Goldie: Dr. Goldie’s research focuses on developing and validating computer-based models linking the basic biology of a disease and its epidemiology to population-based outcomes. She uses these models within a decision analytic framework to synthesize data, identify key knowledge gaps, and evaluate the clinical benefits, public health impact, and cost-effectiveness of alternative preventive and treatment interventions. Her focus in the last several years has been on three viruses of major public health importance: human papillomavirus, human immunodeficiency virus, and hepatitis.
Jim Kim: A founder and former executive director of PIH. He currently serves as chief of the Division of Social Medicine and Health Inequalities at Brigham and Women’s Hospital; director of the François Xavier Bagnoud Center for Health and Human Rights; chair of the Department of Social Medicine at Harvard Medical School; and Matt’s boss. Dr. Kim is also the former director of the WHO’s HIV/AIDS department.

Arthur Kleinman: A Professor of Anthropology in the Faculty of Arts and Sciences and Professor of Medical Anthropology in the Faculty of Medicine. From 1991 to 2000, Dr. Kleinman chaired the Department of Social Medicine at HMS. Dr. Kleinman has practiced as a psychiatrist and is an expert on depression. He will be teaching Anthro 1825 in the fall.
Tom La Salvia: Administrator who took over HIGH when Chris Murray left.
Stephen Lewis: The Secretary-General has appointed Stephen Lewis as his Special Envoy for HIV/AIDS in Africa. Mr. Lewis, who served as Deputy Executive Director of the United Nations Children's Fund (UNICEF) from 1995-1999, and former Canadian Ambassador to the United Nations, will be responsible for ensuring follow-up to the African summit on HIV/AIDS, tuberculosis and other infectious diseases held in Abuja, Nigeria, last April, and to next month's United Nations General Assembly special session on HIV/AIDS, as related to Africa.
Ira Magaziner: The Chairman of Clinton Foundation International Development Initiative. He spoke in a panel with Paul Farmer at Harvard in 2007 for “Step It Up”.

Chris Murray: A professor of global health at the University of Washington, and head of its Institute of Health Metrics and Evaluation. Before coming to the UW in May of 2007, Murray was a Professor of Public Policy, Professor of Social Medicine, and director of HIGH at Harvard. Before coming to Harvard, Murray worked in the WHO. He left Harvard for UW because of a $105M Global Health grant that the Gates Foundation gave UW.
Amartya Sen: A Professor in the departments of Economics and Philosophy who won the Nobel Memorial Prize in Economic Sciences in 1998 for his work on famine, human development theory, welfare economics, and the underlying mechanisms of poverty, and political liberalism.

Bruce Walker: A leader in HIV/AIDS research for over 25 years. He is a Professor of Medicine and Director of the Division of AIDS at Harvard Medical School and director of the Partners AIDS Research Center at MGH. Dr. Walker is also renowned for having opened a state-of-the-art research facility/clinic/medical training center in Durban, South Africa.
Dyann Wirth: Chair of the department of immunology and infectious diseases at HSPH and an associate member of the Broad Institute, where she co-directs the Infectious Disease Initiative. An expert in tropical disease and molecular microbiology, she has developed many of the molecular genetic tools used in the investigation of malaria and leishmania. Her laboratory was the first to discover multi-drug resistance mechanisms in these organisms.

Guide to Navigating Global Health at Harvard

Part 2: Recommended Reading List
Books (General)
Health and Human Rights
Mountains Beyond Mountains – Tracy Kidder

Dying for Growth – ed. Jim Kim

Pathologies of Power – Paul Farmer

Infections and Inequalities – Paul Farmer

The Invisible Cure – Helen Epstein
Economics
End of Poverty – Jeff Sachs

The White Man’s Burden – William Easterly

The Shock Doctrine – Naomi Klein

Globalization and its Discontents – Joseph Stiglitz



Making Globalization Work – Joseph Stiglitz

Books and Articles (Initiative Specific)
Licensing


  • Strong Medicine – Michael Kremer (Harvard Economics Professor)

  • Addressing Global Health Inequities: An Open Licensing Approach for University Innovations – http://www.essentialmedicine.org/cs/wp-content/uploads/2006/11/20-2_spring-2005_2-benkler.pdf

  • Closing the access gap for health innovations: an open licensing proposal for universities-http://www.globalizationandhealth.com/content/3/1/1


Medical Information Equity


  • Excluding the poor from accessing biomedical literature: A rights violation that impedes global health, http://www.hhrjournal.org/index.php/hhr/article/viewArticle/20/88#refs2

  • Internet in Africa http://www.npr.org/templates/story/story.php?storyId=94415421&ft=1&f=1004


Missing Medicines – all articles can be found at http://isites.harvard.edu/icb/icb.do?keyword=k33941&pageid=icb.page142708


  • Control of Neglected Tropical Diseases –Peter Hotez, http://www451.pair.com/hupa/1018.pdf

  • Incorporating Appropriate Technology into North American Schools of Public Health - Peter Hotez, http://www451.pair.com/hupa/HotezetalPAJPH20062.pdf

  • “Rapid-Impact Interventions”: How a Policy of Integrated Control for Africa’s Neglected

  • Tropical Diseases Could Benefi t the Poor - David H. Molyneux, Peter J. Hotez*, Alan Fenwick, http://www451.pair.com/hupa/MolyneuxetalPLoSMedicine2005.pdf

Political Advocacy – see www.healthgap.org


  • The 2008 Stop AIDS Campaign Summary - 08.Stop.AIDS Combined Global/Domestic Platform

  • The Great Harvard Drug Scandal-Did a bitter power struggle keep life-saving AIDS medicine out of Africa? - John Wolfson, http://www.bostonmagazine.com/articles/the_great_harvard_drug_scandal/

  • Brook Baker - "How the IMF Restricts Health/Education Sector Spending"

  • Strategies in Political Advocacy - Birddogging 101: How to take your demands right to the Candidates



Web Resources
08-STOP-AIDS Listserv- With the presidential election just around the corner, this listserv will provide you with useful updates on presidential platforms and opportunities for action. Sign up at www.08stopaids.org.
AIDS Action Committee Action Alerts and Blog – Domestic and State HIV/AIDS Advocacy Issues, sign up for action alerts at www.aac.org. Also check out their blog at blog.aac.org.
Clinton Foundation Newsletter – Follow the work that the Clinton Foundation is doing by signing up for the newsletter at www.clintonfoundation.org.
E-Journal Access at Harvard - http://sfx.hul.harvard.edu/sfx_local/az/
Global Health Delivery Online and Blog- Learn more about global health delivery through discussions on www.ghdonline.org. Hear about the latest news and updates on the GHD project globalhealthdelivery.org/blog.
Kaiser Daily HIV/AIDS Report – Daily news clips of domestic and global AIDS issues, both news and opinion pieces, mostly US and UK newspapers, sign up at www.kaisernetwork.org
Harvard College Global Health and AIDS Coalition Email List- To share information and engage in dialogue with other HCGHAC members, and to stay up-to-date on HCGHAC news, email Jon Weigel (jweigel@fas.harvard.edu).
Health and Human Rights Journal - http://www.hhrjournal.org/index.php/hhr - edited by Paul Farmer
HEALTHGAP Listserv- To hear about the most recent news and action alerts regarding political advocacy, visit www.healthgap.org, and sign up for the listserv by emailing info@healthgap.org.
Harvard Initiative for Global Health listserv- Stay up to date on global events at Harvard by signing up for the HIGH listserv. Email globalhealth@harvard.edu to sign up.
Student Global AIDS Campaign List- action alerts and bi-weekly newsletter on global AIDS issues, sign up www.fightglobalaids.org

Universities Allied for Essential Medicines Listserv – journal or newspaper articles concerning neglected diseases, licensing, intellectual property issues related to global health. Email Neha if you wish to be added to listserv, gupta@fas.harvard.edu.

Videos
GHD Videos - http://globalhealthdelivery.org/blog/?page_id=233


  • Global Health Equity by Paul Farmer at MIT School of Humanities, Arts, and Social Sciences, November 15, 2007

  • http://mitworld.mit.edu/play/512/noreal/Bridging the Delivery Gap to Global Health by Jim Yong Kim at MIT Sloan School of Management, November 19, 2007

  • The Future of Global Health by Jim Yong Kim at Boston University Sargent College of Health and Rehabilitation Sciences, December 4, 2007

  • Announcement of the Global Health Delivery Initiative during the Clinton Global Initiative 2007 Annual Meeting in September


Other Videos


  • Joseph Stiglitz and Ken Rogoff Discuss Globalization and its Discontents- http://info.worldbank.org/etools/BSPAN/PresentationView.asp?PID=325&EID=145

  • Agnes Binagwaho, Executive Secretary of Rwanda’s National AIDS Control Commission - http://www.worldbank.org/afr/debriefing/binagwaho/default.htm



Guide to Navigating Global Health at Harvard

Part 3: Courses at Harvard*
*[not meant to be a complete and extensive list, but these are some we would recommend checking out]
Anthropology 1825. Health, Culture and Community: Case Studies in Global Health [Fall, Tu., Th., 10-11:30]

Jim Yong Kim (Medical School), Paul Farmer (Medical School), and Arthur Kleinman

Examines, through lecturers and case-based discussions, a collection of global health problems rooted in rapidly changing social structures that transcend national and other administrative boundaries. Students will explore case studies (addressing AIDS, tuberculosis, mental illness, and other topics) and a diverse literature (including epidemiology, anthropology, history, and clinical medicine), focusing on how a broad biosocial analysis might improve the delivery of services designed to lessen the burden of disease, especially among those living in poverty.


Anthropology 2736. Medical Anthropology of Contemporary Africa [Spring, Th., 2-4]

Duana Fullwiley

This course will examine the health effects of larger problems facing Africa today, including military and humanitarian HIV/AIDS interventions, genetic studies and offshore clinical trials, ethnic and state violence, economic crisis, resource extraction and migration.


Chemistry 201. Organic Synthesis and Genomic Medicine [Fall, Tu., Th., 10-11:30]

Stuart L. Schreiber

Organic Synthesis and Genomic Medicine, teaches advanced students in chemistry and chemical biology the principles that underlie modern synthetic organic chemistry and genome biology, and the coordination of the two disciplines, especially using chemical biology, towards genomic medicine. For example, the course will explore how synthetic organic chemistry could provide a general mechanism to exploit the dramatic insights being gained from modern human genetics in order to develop safe and effective therapeutics for currently intractable diseases.



Prerequisite: A grade of A in Chemistry 30.
*Economics 980o. Health, Education, and Development [Fall, Th., 2-4]

Erica M. Field

Advanced course addresses health and education issues in developing countries from the standpoint of economics, with a focus on modeling techniques and econometric methods. General topics include demographic transition, household models of production, and the role of health and educational inputs. Specific topics include: the return to education in developing countries, structural problems in delivery, education finance, health inequality, technology adoption and behavior, AIDS, and the impact of disease.



Note: A research paper is required. Concentrators may not take pass/fail.

Prerequisite: Economics 1010a (or 1011a) and 1123 (or 1126).

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