CLINICAL SCIENCE FOCUS SESSION
Imaging in Psychiatry
Alsh
13:30 - 15:30
Chairs: Mark A. van Buchem
Catriona Good
13:30
|
425.
|
Detecting Hippocampal Shape Change in Patients At-Risk for Psychosis
Stephen Wood1, Geoff Stuart1, Dennis Velakoulis1, Deidre Smith1, Lisa Phillips2, Patrick McGorry2, Patricia Desmond3, Christos Pantelis4
1Mental Health Research Institute, Parkville, Victoria, Australia; 2PACE Clinic, Parkville, Victoria, Australia; 3Royal Melbourne Hospital, Melbourne, Victoria, Australia; 4Sunshine Hospital,, St Albans, Victoria, Australia.
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13:40
|
426.
|
Unbiased Estimation of Fornix and Hippocampal Volume on Co-axial MR Images: Application in the Study of Patients with Organic Amnesia
Qi-Yong Gong1, Daniela Montaldi2, Andrew R Mayes2, John Aggleton3, John R Hanley4, Neil Roberts1
1Magnetic Resonance and Image Analysis Research Centre (MARIARC), Liverpool, England, UK; 2University of Liverpool, Liverpool, UK; 3University of Wales, Cardiff, UK; 4University of Essex, UK.
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13:50
|
427.
|
Frontal and Temporal Lobe Brain Volumes in Patients with Idiopathic Parkinson's Disease and Treatment-induced Hallucinations
Jacqueline M Graham1, Nigel Hoggard1, Richard A Grünewald1, Paul D Griffiths1
1University of Sheffield, Sheffield, UK.
|
14:00
|
428.
|
Alien Voices: Neural Correlates of Impaired Self-Monitoring Associated with Auditory Hallucinations in Schizophrenia
Cynthia H.Y. Fu1, Nanda Vythelingum1, Mick J. Brammer1, Chris Andrew1, David Gasston1, Steve Williams1, Edson Amaro Jr1, Philip K. McGuire1
1Institute of Psychiatry, London, UK.
|
14:10
|
429.
|
A Twin Study in Schizophrenia: Preliminary Relaxometry Results
Vít Herynek1, Monika Dezortová1, Filip Spaniel2, Tomás Hájek2, Milan Hájek1
1Institute for Clinical and Experimental Medicine, Prague, Czech Republic; 2Psychiatric Center, Prague, Czech Republic.
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14:20
|
430.
|
Abnormalities in Corpus Callosum Signal Intensity in Schizophrenia.
Vaibhav A. Diwadkar1, Elizabeth L. Dick2, Keith A. Harenski1, Rupali Kotwal1, Michael D. Debellis1, Jay W. Pettegrew2, Matcheri S. Keshavan1
1Western Psychiatric Institute and Clinic, University of Pittsburgh, Pittsburgh, PA, USA; 2University of Pittsburgh, Pittsburgh, PA, USA.
|
14:30
|
431.
|
Region Specific Effects of Amphetamine on Brain Activation Detected with fMRI
S. J. Uftring1, S. R. Wachtel1, D. Chu2, C. Mccandless1, D. N. Levin1, H. De Wit1
1University of Chicago, Chicago, IL, USA; 2Fonar Corporation, Melville, NY, USA.
|
14:40
|
432.
|
Regional Distribution of Brain Structural Abnormalities in Chronic Cocaine and Alcohol Abuse Determined by Volumetric MRI
Joseph O'Neill1, Valerie A Cardenas1, Dieter J Meyerhoff1
1University of California, San Francisco, San Francisco, CA, USA.
|
14:50
|
433.
|
4T fMRI Evaluation of Cerebral Blood Vessel Function in Cocaine-Dependent Subjects
Jing-Huei Lee1, F. W. Telang1, Charles Springer1, Nora Volkow2
1Brookhaven National Laboratory, Upton, NY, USA; 2State University of New York at Stony Brook, Stony Brook, NY, USA.
|
15:00
|
434.
|
Reduction of Functional Connectivity in the Hippocampus of Chronic Human Cocaine Users Detected by Functional MRI
ShiJiang Li1, Amy Kaczmarowski1, Zhu Li1, Gaohong Wu1, Elliot A. Stein1, Hugh Garavan1, Robert Risinger1
1Medical College of Wisconsin, Milwaukee, WI, USA.
|
15:10
|
435.
|
A Diagnostic Analysis of Magnetization Transfer Ratio (MTR) Histograms in Neuropsychiatric Systemic Lupus Erythematosus (NPSLE) Patients
Jamshid Dehmeshki1, G.P.Th. Bosma2, M. J. Rood2, T. W.J. Huizinga2, Mark Van Buchem2, Paul Stephen Tofts1
1Institute of Neurology, London, England, UK; 2Leiden University Medical Center, Leiden, Netherlands.
|
15:20
|
436.
|
Correlation of Apparent Diffusion Coefficient (ADC) Histogram Parameters with Clinical Functioning in Neuropsychiatric Systemic Lupus Erythematosus (NPSLE)
G.P.Th. Bosma1, T.W.J. Huizinga1, E.L.E.M. Bollen1, H.A.M. Middelkoop1, M.A. Van Buchem1
1Leiden University Medical Center, Leiden, The Netherlands.
|
Rapid Imaging
Clyde Auditorium
16:00 - 18:00
Chairs: John Pauly
Simon J. Doran
16:00
|
437.
|
Hyperechoes - Basic Principles and Applications
Jürgen Hennig1, Klaus Scheffler1
1University Hospital Freiburg, Freiburg, Germany.
|
16:12
|
438.
|
T2-Weighted 3D Spin-Echo Train Imaging of the Brain at 3 Tesla: Reduced Power Deposition Using Low Flip-Angle Refocusing RF Pulses
John P. Mugler III1, Lawrence L. Wald2, James R. Brookeman1
1University of Virginia, School of Medicine, Charlottesville, VA, USA; 2Massachusetts General Hospital, Charlestown, MA, USA.
|
16:24
|
439.
|
Characterization of the Transient Response in Steady-State Sequences
B. A. Hargreaves1, Shreyas Vasanawala1, John M. Pauly1, Dwight G. Nishimura1
1Stanford University, Stanford, CA, USA.
|
16:36
|
440.
|
Magnetization Preparation during the Steady State: Fat Saturated 3D TrueFISP
Klaus Scheffler1, Oliver Heid2, Jürgen Hennig1
1Universität Freiburg, Freiburg, Germany; 2Siemens Medical Imaging, Erlangen, Germany.
|
16:48
|
441.
|
3D True-FISP Imaging with Fat Suppression
Walter Block1, Thomas Hany1, Andrew Barger1
1University of Wisconsin-Madison, Madison, WI, USA.
|
17:00
|
442.
|
Real-Time Spiral SSFP Cardiac Imaging
Craig Meyer1, John M. Pauly1, Krishna Nayak1, Michael Mcconnell1, Albert Macovski1, Dwight G. Nishimura1, Bob Hu1
1Stanford University, Stanford, CA, USA.
|
17:12
|
443.
|
Cardiac Imaging using Echo-Planar Steady-State Free Precession
Glenn S. Slavin1, Thomas K.F. Foo1
1GE Medical Systems, Milwaukee, WI, USA.
|
17:24
|
444.
|
Using UNFOLD to Remove Artifacts in Dynamic Imaging
Bruno Madore1
1Harvard University, Boston, MA, USA.
|
17:36
|
445.
|
Adaptive Sensitivity Encoding Incorporating Temporal Filtering (TSENSE)
Peter Kellman1, Frederick H. Epstein2, Elliot R. McVeigh1
1National Institutes of Health, Bethesda, MD, USA; 2University of Virginia, Charlottesville, VA, USA.
|
17:48
|
446.
|
Off-Resonance Artifacts in Single Shot EPI using Partially Parallel Imaging
Mark Griswold1, Peter Jakob1, Robin Heidemann1, Mathias Nittka1, Jianmin Wang2, Berthold Kiefer1
1Universität Würzburg, Physikalisches Institut, Würzburg, Germany; 2Siemens Medical Engineering, Erlangen, Germany.
|
Myocardial Tagging and Hemodynamics
Lomond
16:00 - 18:00
Chairs: Leon Axel
John N. Oshinski
16:00
|
447.
|
Limiting Dilatation Improves Ventricular Function in a Model of Myocardial Infarction as Assessed by Tissue-tagged MRI
James J Pilla1, Aaron S Blom1, Daniel J Brockman1, Lawrence Dougherty1, Frank W Bowen1, Joseph Giammarco1, Qing Yuan1, Victor Ferrari1, Michael A Acker1, Leon Axel1
1University of Pennsylvania Medical Center, Philadelphia, PA, USA.
|
16:12
|
448.
|
Myocardial Tagging with 3D-CSPAMM
Salome Ryf1, Marcus Spiegel1, Oliver M Weber1, Peter Boesiger1
1University and ETH Zurich, Zurich, Switzerland.
|
16:24
|
449.
|
MR Tagging of the Entire Cardiac Cycle: Regional Analysis of Normal Subjects and Hypertrophic Cardiomyopathy Using A New Quantity for Assessment of Regional Cardiac Function
Daniel B. Ennis1, Frederick H. Epstein2, Elliot R. McVeigh3, Andrew E. Arai3
1Johns Hopkins University School of Medicine, Baltimore, MD, USA; 2University of Virginia, Charlottesville, VA, USA; 3National Institutes of Health, Bethesda, MD, USA.
|
16:36
|
450.
|
MRI Tagging in Mice After Acute Myocardial Infarction Demonstrates Heterogeneity of Function in the Non-Infarcted Zone
Frederick H. Epstein1, Zequan Yang1, Wesley D. Gilson1, Christopher M. Kramer1, Brent A. French1, Stuart Scott Berr1
1University of Virginia, Charlottesville, VA, USA.
|
16:48
|
451.
|
Improved Harmonic Phase (HARP) Instantaneous Myocardial Strain Maps
Joost P.A. Kuijer1, Eric Jansen1, J. Tim Marcus1, Robert M. Heethaar1
1University Hospital Vrije Universiteit, Amsterdam, Netherlands.
|
17:00
|
452.
|
Relationship Between k-space Trajectory and Artifacts in Breath Held, Gated Segmented k-space Imaging
Moriel NessAiver1
1University of Maryland at Baltimore, Baltimore, MD, USA.
|
17:12
|
453.
|
Estimation of Time-varying Three-dimensional Relative Pressure Fields within the Human Heart
Tino Ebbers1, Lars Wigström1, Ann F Bolger2, Bengt Wranne1, Matts Karlsson1
1Linköping University, Linköping, Sweden; 2University of California San Francisco, San Francisco, CA. USA.
|
17:24
|
454.
|
Free Breathing Fourier Velocity Encoded M-Mode MRI for Measurement of Aortic Distensibility
Manojkumar Saranathan1, Christopher J. Hardy2, Xuli Zong2, Vincent B. Ho3
1GE Medical Systems, Waukesha, WI, USA; 2GE Corporate Research & Development, Schenectady, NY, USA; 3Uniformed Services University of the Health Sciences, Bethesda, MD, USA.
|
17:36
|
455.
|
MRI Assessment of Atrial Septal Defects in Adults
Xiuling Qi1, Naeem Merchant2, Fiona Walker2, Gary D. Webb2, Peter McLaughlin2, Jeffrey Stainsby1, Graham Wright1
1Sunnybrook and Women's College Health Sciences Centre, University of Toronto, Toronto, Canada; 2University Health Network, University of Toronto, Toronto, Canada.
|
17:48
|
456.
|
Measurements of Left Ventricular Dimensions and Function using Steady-State Free Precession Imaging: Comparison with Turbo Gradient Echo Imaging
Sven Plein1, Timothy N. Bloomer1, John P. Ridgway1, Tim R. Jones1, Gavin J. Bainbridge1, Mohan U. Sivananthan1
1Leeds General Infirmary, Leeds, England, UK.
|
MR PHYSICS AND TECHNIQUES FOR CLINICIANS
Hall 2
16:00 - 18:00
Chairs: Frank R. Korosec
Joseph C. McGowan
Educational Objectives
At the conclusion of this course, participants should be able to
-
Define and describe the fundamental principles of MR imaging, including spin magnetization, the Larmor relationship, relaxation phenomena, and the process of using the spin magnetization to produce an image.
-
Explain imaging pulse sequences based upon spin and gradient echoes, including fast spin echo and echo planar techniques.
-
Design MR imaging protocols for diagnostic applications considering image contrast, spatial resolution, acquisition time, signal-to-noise ratio, and artifacts.
-
Describe the principles and capabilities of various advanced MR techniques including perfusion and diffusion, functional, interventional, and cardiac MR imaging.
16:00 Image Quality and Acquisition Speed
Norbert J. Pelc
16:40 Echo Planar Imaging
Marcus Alley
17:20 Perfusion and Diffusion Imaging
Scott D. Swanson
Animal Brain MRI: Ischemia and Infarction
Hall 5
16:00 - 18:00
Chairs: Bruce R. Rosen
Peter R. Allegrini
16:00
|
457.
|
Separating MR Changes of Intra- and Extracellular Water in Focal Cerebral Ischemia in the Rat Brain
Matthew Silva1, Tsuyoshi Omae2, Karl Helmer1, Fuhai Li2, Marc Fisher2, Christopher Sotak1
1Worcester Polytechnic Institute, Worcester, MA, USA; 2UMass Memorial Health Care, University of Massachusetts Medical School, Worcester, MA, USA.
|
16:12
|
458.
|
Mismatch between Lactate and the Apparent Diffusion Coefficient of Water in Progressive Focal Ischemia
Toshihiko Ebisu1, Tetsuro Takegami2, Yoshitaka Bito3, Satoshi Hirata3, Yukari Yamamoto3, Masahiro Umeda1, Shoji Naruse2, Chuzo Tanaka1
1Meiji University of Oriental Medicine, Kyoto, Japan; 2Kyoto Prefectural University of Medicine, Kyoto, Japan; 3Hitachi, Ltd., Tokyo, Japan.
|
16:24
|
459.
|
Comparison of the Temporal and Spatial Evolution of the Water Apparent Diffusion Coefficient and T2 Following Transient Middle Cerebral Artery Occlusion in Rats
Matthew Silva1, Fuhai Li2, Marc Fisher2, Christopher Sotak1
1Worcester Polytechnic Institute, Worcester, MA, USA; 2UMass Memorial Health Care, University of Massachusetts Medical School, Worcester, MA, USA.
|
16:36
|
460.
|
Mild Hypothermia Attenuates Cyclooxygenase-2 mRNA Expression and Transient Water ADC Reduction during Permanent Focal Ischemia in Rats
Anthony Mancuso1, Nikita Derugin2, Theresa A Marsh3, Kazushi Hara3, Kong L Daniel2, Frank R Sharp4, Philip R. Weinstein2
1University of Pennsylvania, Philadelphia, PA, USA; 2University of California, San Francisco, San Francisco, CA, USA; 3Dept. of Veterans Affairs Medical Center, San Francisco, CA, USA; 4University of Cincinnati, Cincinnati, OH, USA.
|
16:48
|
461.
|
Ischaemic Preconditioning in the Rat Brain: A Longitudinal Magnetic Resonance Imaging (MRI) Study.
Paul G Mullins1, David G Reid2, Paul Hockings2, Sarah J Hadingham3, Colin A Campbell3, Jonathan Chalk4, David Doddrell4
1University of New Mexico, Albuquerque, NM, USA; 2SmithKline Beecham Pharmaceuticals, Welwyn, England, UK; 3SmithKline Beecham Pharmaceuticals, Harlow, Essex, UK; 4University of Queensland, Brisbane, QLD, Australia.
|
17:00
|
462.
|
SB 234551 Improves Cortical Collateral Perfusion Following Permanent MCAO in the Rat
Stephen C. Lenhard1, Jeffrey J. Legos1, Robin E. Haimbach1, Ross G. Bentley1, Thomas R. Schaeffer1, Frank C. Barone1, Eliot H. Ohlstein1, Susanta K. Sarkar1, Andrew A. Parsons1, Sudeep Chandra1
1SmithKline Beecham Pharmaceuticals, King of Prussia, PA, USA.
|
17:12
|
463.
|
A Comparative Stroke Study between Wild-Type and PARP Transgenic Mice Using Diffusion MRI
R. Xue1, S. Goto1, M. Sawada1, P. D. Hurn1, V. L. Dawson1, T. M. Dawson1, R. J. Traystman1, P. C.M. van Zijl1, S. Mori1
1The Johns Hopkins University, School of Medicine, Baltimore, MD, USA.
|
17:24
|
464.
|
Delayed rt-PA Treatment Induces Rapid Blood-Brain Barrier Breakdown and Subsequent Hemorrhagic Transformation in a Rat Embolic Stroke Model
Rick M. Dijkhuizen1, Minoru Asahi1, Ona Wu1, Bruce R. Rosen1, Eng H. Lo1
1Massachusetts General Hospital, Charlestown, MA, USA.
|
17:36
|
465.
|
Topographical Representation of Functional Recovery in the Brain Detected by fMRI Analysis
Zhengguang Chen1, Masahiro Abo2, Li-Ju Lai1, Torsten Reese3, Satoshi Miyano2, Kyozo Yonemoto2, Börje Bjelke1
1Karolinska Hospital, Karolinska Institute, Stockholm, Sweden; 2Jikei University School of Medicine, Tokyo, Japan; 3Present address: SmithKline Beecham, Welwyn, Herts, London, UK.
|
17:48
|
466.
|
Quantitative Sodium MRI of Evolving Focal Brain Ischemia in the Rat
Fernando Boada1, A. Kharlamov2, D. K. Kim2, E. D. Reid1, Ileana Hancu1, S. C. Jones2
1University of Pittsburgh, Pittsburgh, PA, USA; 2Allegheny General Hospital, Pittsburgh, PA, USA.
|
MRS of White Matter and Degenerative Diseases
Hall 1
16:00 - 18:00
Chairs: Douglas L. Arnold
Dorothée P. Auer
16:00
|
467.
|
Absolute Quantification of Metabolites in White Matter using MR Spectroscopy in Patients with MS or Syndromes Suggestive of MS with Normal MRI Scans of the Brain
Maria Gustafsson1, Peter Lundberg1, Anne-Marie Landtblom1
1University Hospital of Linköping, Linköping, Sweden.
|
16:12
|
468.
|
Proton MR Spectroscopy with Metabolite-Nulling Reveals Elevated Macromolecules in Acute MS
Irina Mader1, Uwe Seeger1, Robert Weissert1, Uwe Klose1, Thomas Naegele1, Arthur Melms1, Wolfgang Grodd1
1Tuebingen University, Tuebingen, Germany.
|
16:24
|
469.
|
T2-based Volume Correction for Edema in Single Volume MRS of Contrast-Enhancing Multiple Sclerosis Lesions
Gunther Helms1
1Karolinska Institute, Karolinska Hospital, Stockholm, Sweden.
|
16:36
|
470.
|
In Vivo 3D 1H MRS of T1-Hypointense Lesions in Relapsing-Remitting Multiple Sclerosis
Belinda S.Y. Li1, David M. Moriarty1, Juleiga Regal1, Lois J. Mannon2, Robert I. Grossman2, Oded Gonen1
1Fox Chase Cancer Center, Philadelphia, PA, USA; 2University of Pennsylvania, Philadelphia, PA, USA.
|
16:48
|
471.
|
Proton Magnetic Resonance Spectroscopy in Assessing Axonal Loss in the Corpus Callosum Related with Volume of Regional T1 Lesion Load in Multiple Sclerosis
Joonmi Oh1, Daniel Pelletier1, Sarah J Nelson1
1University of California San Francisco, San Francisco, CA, USA.
|
17:00
|
472.
|
1H MRS and Volumetric MRI Studies of Multiple Sclerosis: Correlations between Brain Metabolite Levels, Brain Atrophy, and Cognitive Functions
Wei Huang1, C. Christodoulou1, Dongqing Chen1, Alina Tudorica1, Patricia Roche1, W. Scherl1, R. Peyster1, Clemente Roque1, P. Melville1, V. Geronimo1, Terry M. Button1, Z. Liang1, Lauren Krupp1
1State University of New York at Stony Brook, Stony Brook, NY, USA.
|
17:12
|
473.
|
Thalamic Neuronal Loss in Multiple Sclerosis: a Combined Structural and Spectroscopic Study
Marzena Wylezinska1, Alberto Cifelli1, Paul Matthews1, Peter Jezzard1
1University of Oxford, John Radcliffe Hospital, Oxford, UK.
|
17:24
|
474.
|
Metabolic Differences Between Multiple Sclerosis Subtypes Measured by Quantitative MR Spectroscopy
Jullie W. Pan1, Patricia Coyle2, Lauren Krupp2, John N. Whitaker3, K. Bashir3, Hoby Hetherington4
1Albert Einstein College of Medicine, Bronx, NY, USA; 2State University of New York at Stony Brook, Stony Brook, NY, USA; 3University of Alabama at Birmingham, Birmingham, AL, USA; 4Yeshiva University, Albert Einstein College of Medicine, Bronx, NY, USA.
|
17:36
|
475.
|
Brain MR Spectroscopy Follow-up in Aging Women and Men
Paul E. Sijens1, Tom den Heijer2, Sahra E. Vermeer2, Monique M.M.B. Breteler2, Albert Hofman2, Oudkerk Matthijs1
1University Hospital Groningen, Groningen, Netherlands; 2Erasmus University Medical School, Rotterdam, Netherlands.
|
17:48
|
476.
|
Fast Proton MR Spectroscopic Imaging of Temporal Lobe and Hippocampus in Alzheimer's Disease
Wolfgang Block1, Frank Träber1, Frank Jessen1, Sebastian Flacke1, Christoph Manka1, Rolf Lamerichs2, Reinhard Heun1, Ewald Keller1, Hans H. Schild1
1University of Bonn, Bonn, Germany; 2Philips Medical Systems, Best, The Netherlands,
|
Tumor Anti-Vascular Therapy
Forth
16:00 - 18:00
Chairs: John C. Waterton
Robert Brasch
16:00
|
477.
|
Tumor Perfusion Efficiency and Mean Vessel Size Measured in Experimental Human Gliomas
Scott D. Packard1, Tomogatsu Ichikawa2, Joseph B. Mandeville3, Ennino. A. Chiocca2, Bruce Rosen3, John J. A. Marota4
1Massachusetts Institute of Technology, Massachusetts General Hospital, Charlestown, MA, USA; 2Massachusetts General Hospital, Boston, MA, USA; 3Harvard University, Massachusetts General Hospital, Charlestown, MA, USA; 4Harvard University Medical School, Boston, MA, USA.
|
16:12
|
478.
|
ZD6474, a VEGF Signalling Inhibitor: Effects on DCEMRI in Human Tumour Xenografts and Approaches to the Analysis of the Ktrans Maps
David Checkley1, Jean Tessier1, Stephen Wedge1, Michael Dukes1, Jane Kendrew1, John C Waterton1
1Astrazeneca, Macclesfield, Cheshire, UK;
|
16:24
|
479.
|
Anti-Angiogenic Agent TNP-470 Significantly Decreases Permeable Regions
Zaver M. Bhujwalla1, Dmitri Artemov1, Kshama Natarajan1, Paul E. G. Kristjansen2
1Johns Hopkins University, School of Medicine, Baltimore, MD, USA; 2University of Copenhagen, Copenhagen, Denmark;
|
16:36
|
480.
|
A Dynamic Contrast-Enhanced Study of the Effects of the Novel Tumour Vascular Targeting Agent ZD6126 in GH3 Rat Tumours
Dominick J.O. Mcintyre1, Simon P. Robinson1, Franklyn A. Howe1, John R. Griffiths1, Jean J. Tessier2, David Checkley2, David C. Blakey2, John C. Waterton2
1St. George's Hospital Medical School, London, UK; 2AstraZeneca, Macclesfield, Cheshire, UK.
|
16:48
|
481.
|
Dynamic Contrast-Enhanced MRI Evaluation of the Effects of ZD6126 on Tumor Vasculature
Jeffrey L. Evelhoch1, Zhanquan He1, Lisa Polin1, Thomas H. Corbett1, David C Blakey2, John C. Waterton2
1Wayne State University, Detroit, MI, USA; 2Astrazeneca, Alderley Park, Cheshire, England, UK.
|
17:00
|
482.
|
Combretastatin Reduces Blood Flow in Animal and Human Tumours, Demonstrated by Dynamic MRI
Susan M Galbraith1, Martin Lodge2, N. Jane Taylor2, Ross Maxwell1, Gill M Tozer1, James J Stirling2, Luiza Sena3, Anwar Padhani2, Gordon Rustin2
1Gray Laboratory Cancer Research Trust, Northwood, Middlesex, UK; 2Mount Vernon Hospital, Northwood, Middlesex, UK; 3Drug Development Office, Cancer Research Campaign, UK.
|
17:12
|
483.
|
Dynamic Gadolinium-Enhanced MRI Evaluation of Tumor Vascularity in Humans: Determination of Physiologic Parameters and Effects of Combretastatin A4 Phosphate
Mark Alan Rosen1, Sarah Englander1, Peter B. O'Dwyer1, James Stevenson1, Mitchell Schnall1
1University of Pennsylvania, Philadelphia, PA, USA.
|
17:24
|
484.
|
MRSI of Antiangiogenesis/Radiation in Pediatric Gliomas
Loukas Astrakas1, Aria Tzika1, Tina Poussaint1, Marc Kieran2
1Children's Hospital and Harvard Medical School, Boston, MA, USA; 2Dana Farber Cancer Institute and Harvard Medical School, Boston, MA, USA.
|
17:36
|
485.
|
Reproducibility of Quantitative Permeability Measurements in Dynamic Contrast-Enhanced MRI Studies
Martin A Lodge1, Susan M Galbraith1, N. Jane Taylor1, Ross Maxwell1, J James Stirling1, Hiram Baddeley1, Gordon Js Rustin1, Anwar R. Padhani1
1Mount Vernon Hospital, Northwood, UK.
|
17:48
|
486.
|
Reproducibility of Blood Volume and Relative Recirculation Measurements in Cerebral Glioma using T2* Techniques
Andrea Kassner1, Xiaoping Zhu2, Ka-Loh Li2, Alan Jackson2
1Philips Medical Systems, Leeds, England, UK; 2University of Manchester, Manchester, England, UK.
|
MR Spectroscopy of Animal Brain
Alsh
16:00 - 18:00
Chairs: Rolf Gruetter
Nicolau Beckmann
16:00
|
487.
|
Transient Hypoxia Studied By Proton Spectroscopy and Diffusion-Weighted Imaging in Embryonic Chicken Brain In Ovo
John Thornton1, Ernest Cady1, Roger Ordidge1, Suzanne Miller1, Donald Peebles1
1University College London, London, UK.
|
16:12
|
488.
|
In vivo Quantification of Metabolites in the Hippocampus, Striatum, and Cortex of the Developing Neonatal Rat.
Ivan Tkac1, Raghavendra Rao1, Michael K Georgieff1, Rolf Gruetter1
1University of Minnesota, Minneapolis, MN, USA.
|
16:24
|
489.
|
Effects of Dexamethasone Pretreatment on Brain and Whole Body Metabolism in a Neonatal Hypoxia-Ischemia Animal Model
Jian-li Wang1, Shannon Beabes1, Bernard Dardzinski2, Michael B. Smith1
1Pennsylvania State University, Hershey, PA, USA; 2University of Cincinnati, Cincinnati, OH, USA.
|
16:36
|
490.
|
Cellular and Developmental Tissue Distribution of NAA Catabolic Enzyme, Aspartoacylase. Insights into NAA Function.
Kishore Bhakoo1, Timothy Craig1, Peter Styles1
1University of Oxford, Oxford, England, UK.
|
16:48
|
491.
|
Biochemical and Histological Correlates of Elevated Lipid Signals after Stroke in Rats
Charles Gasparovic1, Gary A. Rosenberg1, James A. Wallace1, Eduard Y. Estrada1, Kristianna Roberts1, Glenn D. Graham1
1University of New Mexico School of Medicine (UNMSOM), Albuquerque, NM, USA.
|
17:00
|
492.
|
Relationship between Glucose / Glycogen Metabolism and CBF during Insulin-Induced Hypoglycemia In Vivo
In-Young Choi1, Sang-Pil Lee1, Seong-Gi Kim1, Rolf Gruetter1
1University of Minnesota, Minneapolis, MN, USA.
|
17:12
|
493.
|
Glial Uptake of Selectively 13C-Enriched Neurotransmitter Glutamate Observed In Vivo Through 13C-15N Coupling
Keiko Kanamori1, B.D. Ross1
1Huntington Medical Research Institutes, Pasadena, CA, USA.
|
17:24
|
494.
|
A Robust Approach for Spatial Mapping of CMRO2 in Rat Brain Using 17O MRS Imaging Within Two Minutes
Xiao-Hong Zhu1, Runxia Tain1, Jae-Hwan Kwag1, Xiaoliang Zhang1, Hellmut Merkle1, John Paul Strupp1, Kamil Ugurbil1, Wei Chen1
1University of Minnesota, Minneapolis, MN, USA.
|
17:36
|
495.
|
31P and 1H MRS of Brain and Muscle in Guanidino Acetate Methyltransferase Deficient Mice
W.K.J. Renema1, A. Schmidt2, D. Isbrandt2, K. Ulrich3, B. Wieringa1, A. Heerschap1
1University Medical Center Nijmegen, Nijmegen, Netherlands; 2University of Hamburg, Centre for Molecular Neurobiology, Hamburg, Germany; 3University of Hamburg, Pediatric Hospital, Hamburg, Germany.
|
17:48
|
496.
|
Direct Detection of Neural Activity in the Rat Brain with 23Na NMR
Itamar Ronen1, Kamil Ugurbil1, Seong-Gi Kim1
1University of Minnesota, Minneapolis, MN, USA.
|
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