Monday am opening session clyde Auditorium 07: 45 08: 20 Welcome and Medal Presentations



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GE Medical Systems


Argyll (Moat House)

12:30 – 13:30



BASIC SCIENCE FOCUS SESSION (WITH POSTERS)

Rapid Imaging

Clyde Auditorium

Thursday: 13:30 - 15:30



Chairs: Stephen J. Riederer
John P. Mugler
Jürgen Hennig


Please see page 239 for details.



BASIC SCIENCE FOCUS SESSION (WITH POSTERS)

Intraoperative and Miscellaneous Interventional MRI

Forth

Thursday: 13:30 - 15:30



Chairs: Charles L. Truwit
Jens-Peter Schneider


Please see page 273 for details.



CLINICAL SCIENCE FOCUS SESSION
MRS in Neurologic and Psychiatric Diseases

Lomond


13:30 - 15:30
Chairs: Jullie W. Pan
Dieter J. Meyerhoff






13:30

550.

Alterations on Mitochondrial Functionality in Migraine Studied by Functional 1HMRS

R. Tarducci1, O. Presciutti1, P. Sarchielli2, A. Alberti2, V. Gallai2, G. Gobbi1

1Azienda Ospedaliera di Perugia, Perugia, Italy; 2Università di Perugia, Perugia, Italy.



13:40

551.

Effect of Tamoxifen on Brain Chemistry

Thomas Ernst1, Linda Chang1, Kyle Boone1, Dilrukshie Cooray1, Corazon Salvador1, Rowan Chlebowski1

1Brookhaven National Laboratory, Upton, NY, USA.



13:50

552.

A Comparison of Single Voxel Proton MR Spectroscopy and Spectroscopic Imaging in Subjects with HIV-Associated Cognitive Impairment: Results of a Multi-Center Trial

Peter B. Barker1, Martin Pomper1, Linda Bobo1, Thomas Ernst2, K. Zhong2, L. Chang2, Dikoma C. Shungu3, Xiangling Mao3, K. Marder3, D. Shibata4, G. Schifitto4, Ned C. Sacktor1

1Johns Hopkins University, School of Medicine, Baltimore, MD, USA; 2Brookhaven National Laboratory, Upton, NY, USA; 3Columbia University, New York, NY, USA; 4Rochester University, Rochester, NY USA.



14:00

553.

Evaluation and Prognosis of Severe Traumatic Brain Injury Using Single and Multi-Voxel Proton MR Spectroscopy.

Karen Angela Tong1, Barbara Ann Holshouser1, Austin Colohan1, Lori Shutter1

1Loma Linda University, Loma Linda University Medical Center, Loma Linda, California USA.



14:10

554.

1H-MR-spectroscopy and Apparent Diffusion Coefficients of the Hippocampus in Patients with Temporal Lobe Epilepsy

Jörn Kaufmann1, Emrah Düzel1, Sebastian Guderian1, Jens-Max Hopf1, Nils Bodammer1, Martin Kanowski1, Claus Tempelmann1, Hans-Jochen Heinze1

1O.v.G. University, Magdeburg, Germany.



14:20

555.

Frontal Lobe NAA Reductions in Temporal Lobe Epilepsy by 1H MRSI

Joyce Suhy1, Kenneth D. Laxer1, Derek Lee Flenniken1, Jana Axelrad1, Aristides Andres Capizzano1, Michael W Weiner1

1University of California, San Francisco, San Francisco, CA, USA.



14:30

556.

Brain Myo-Inositol Decreases, NAA is Unchanged in Healthy Volunteers in Response to Lithium Administration

Blaise deB. Frederick1, Aimee M. Parow1, Christina M. Demopulos2, Gary S. Sachs2, Caroline Dufault2, Constance M. Moore1, Perry F. Renshaw1

1McLean Hospital Brain Imaging Center, Harvard Medical School, Belmont, MA, USA; 2Massachusetts General Hospital Bipolar Program, Harvard Medical School, Boston, MA, USA.



14:40

557.

Different Relationships among Cortical Amino Acids in Unipolar and Bipolar Depression

Graeme F. Mason1, Amit Anand1, Gerard Sanacora1, Neill Epperson1, Kristin Haga1, Michael Appel1, Andrew W. Goddard1, Dennis S. Charney2, Douglas L. Rothman1, John H. Krystal1

1Yale School of Medicine, New Haven, CT, USA; 2National Institute of Mental Health, USA.



14:50

558.

Electroconvulsive Therapy Induces Metabolic Changes in Severe Depressed Patients in the Anterior Cingulum

Bettina Pfleiderer1, Nikolaus Michael1, Andreas Erfurth1, Patricia Ohrmann1, Matthias Wolgast1, Volker Arolt1, Walter Heindel1

1University of Münster, Münster, Germany.



15:00

559.

Brain Dysfunction in Alcohol Dependence: Neuropsychological and In Vivo Proton MRS Study

Mahesh Kumar1, Atul Ambekar1, N. G. Desai1, H.P. Jhingen1, S. Gupta1, N. R. Jagannathan1

1All India Institute of Medical Sciences, New Dehli, India.



15:10

560.

Region-Specific Changes in Phospholipid Metabolism in Schizophrenia: A 31P Chemical-Shift Imaging Study at 4.0 Tesla

J. Eric Jensen1, Yousef M. Al-Semaan2, Dick J. Drost1, Peter C. Williamson2, Richard W.J. Neufeld3, Ravi S. Menon4

1University of Western Ontario, St. Joseph's Health Centre, London, Ontario, Canada; 2London Health Science Centre, London, Ontario, Canada; 3University of Western Ontario, London, Ontario, Canada; 4The John P. Robarts Research Institute, London, ON, Canada.



15:20

561.

31P NMR Detects Abnormal Phospholipid Composition in Postmortem Schizophrenic Brain

Richard A. Komoroski1, John M. Pearce1, Masao Omori2, W. Sue Griffin1, Robert E. Mrak1, Craig N. Karson3

1University of Arkansas for Medical Sciences (UAMS), Little Rock, AR USA; 2Fukui Medical School, Matsuoka, Fukui Japan; 3Central Arkansas Veterans Healthcare System, Little Rock, AR, USA.




CLINICAL SCIENCE FOCUS SESSION
Breast MR Imaging

Hall 2


13:30 - 15:30
Chairs: Lindsay W. Turnbull
Hadassa Degani






13:30

562.

Optimising Flip-Angles for Improved T1 Calculation in 3D Contrast-Enhanced Breast MR Imaging

Paul Armitage1, Chris Behrenbruch1, Michael Brady1, Niall R. Moore1

1University of Oxford, Oxford, UK.



13:40

563.

Diagnosis of Benign and Malignant Breast Lesions using Multiparametric MRI

Michael Jacobs1, David A. Bluemke1, Zaver Bhujwalla1, Cindy Maranto1, Peter B. Barker1

1Johns Hopkins University, Baltimore, MD, USA.



13:50

564.

Simultaneous Dynamic and Architectural MR Breast Imaging

Lawrence Dougherty1, Hee Kwon Song1, Mitchell D. Schnall1

1University of Pennsylvania Medical Center, Philadelphia, PA, USA.



14:00

565.

Concentric Regional Sampling in Contrast Enhanced Imaging of the Breast

Peter Gibbs1, Lindsay W Turnbull1

1Hull Royal Infirmary, Hull, England, UK.



14:10

566.

A Two Center Clinical Testing of the 3TP Method for Contrast Enhanced Breast MRI.

Edna Furman-Haran1, Hadassa Degani1, Kevin Kirshenbaum2, Frederick Kelcz3

1Weizmann Institute of Science, Rehovot, Israel; 2Illinois Masonic Medical Center, Chicago, IL, USA; 3University of Wisconsin Hospital, Madison, WI, USA.



14:20

567.

Measurements of Regional Blood Flow and Blood Volume in Breast Cancer With MRI

Jean-Paul Delille1, Priscilla J Slanetz2, Eren D Yeh2, Daniel B Kopans2, Leoncio Garrido1

1Massachusetts General Hospital, Harvard Medical School, Charlestown, MA, USA; 2Massachusetts General Hospital, Harvard Medical School, Boston, MA, USA.



14:30

568.

Assessment of Angiogenesis in Breast Lesions Using Dynamic Contrast Enhanced MR Mammography and Immunohistochemical Biomarkers

M. Y. Su1, Y. L. Wan2, Y. C. Cheung2, J. P. Fruehauf3, H. Yu1, A. Kyshtoobayeva3, S. Hsueh2, S. S. Chen2, O. Nalcioglu1

1University of California, Irvine, CA, USA; 2Chang Gung Memorial Hospital, Linkou, Taiwan; 3Oncotech Inc., Irvine, CA, USA.



14:40

569.

Lymph Node Staging with a Lymph Node-Specific Contrast Agent (Sinerem®, Guerbet) in Patients with Breast Cancer

Sven Claude André Michel1, Borut Marincek1, Johannes Fröhlich2, Daniel Nanz1, Daniel Fink1, Rosmarie Caduff1, Rahel Kubik-Huch1

1University Hospital, Zurich, Switzerland; 2Guerbet-Group, Zurich, Switzerland.



14:50

570.

In Vivo Turbo Spin Echo Intensities Correlate with Oestrogen Receptor Status in Breast Tumors.

Patrick J Gilligan1, Orla Mc Cormack2, Fidelma L Flanagan1, Diane Bergin1, Michael J Kerin2, Thomas F Gorey2, Joseph T Ennis3

1Institute of Radiological Sciences, Dublin, Ireland; 2Mater Hospital, Dublin, Ireland; 3Institute of Radiological Sciences, University College Dublin, Dublin, Ireland.



15:00

571.

Evaluation of Hormone Replacement Therapy by MRI

Adrian Knowles1, Clare Kearney2, David Purdie2, Peter Gibbs2, Lindsay W Turnbull2

1Philips Medical Systems, Best, The Netherlands; 2Hull Royal Infirmary, Hull, UK.



15:10

572.

Non-Ridig Registration of Contrast-Enhanced MRI to Quantify Chemotherapy Response in Breast Cancer for Histological Comparison

Christian Behrenbruch1, Paul Armitage1, Michael Brady1, Niall R. Moore1, Charles Hardingham1

1University of Oxford, Oxford, England, UK.



15:20

573.

Assessment of Soya Bean Oil Breast Implants by MRI

Jane Hawnaur1, Mary Wilson2, Edwin Elangovan2, Nigel Bundred2

1University of Manchester, Manchester, England, UK; 2South Manchester University Hospitals Trust, Manchester, England, UK.




CLINICAL SCIENCE FOCUS SESSION
Pediatric MR Spectroscopy

Hall 5


13:30 - 15:30
Chairs: Albert Thomas
Brian David Ross






13:30

574.

Ureidopropionase Deficiency: A Novel Inborn Error of Metabolism Discovered Using Body Fluid NMR Spectroscopy

S. Moolenaar1, U. Engelke1, G. Göhlich-Ratmann2, B. Assmann3, C. Bräutigam3, A. van Kuilenburg4, A. van Gennip4, J. de Jong1, T. Voit2, G. Hoffmann3, P. Vreken4, R. Wevers1

1University Medical Centre, Nijmegen, The Netherlands; 2University Hospital, Essen, Germany; 3University Hospital, Heidelberg, Germany; 4Academic Medical Centre, Amsterdam, The Netherlands.



13:40

575.

In vivo NAA Synthesis Rate in Canavan´s Disease Patients using 13C MRS

Angel Moreno-Torres1, Stefan Bluml1, Brian Ross2

1Rudi Schulte Research Institute, Santa Barbara, CA, USA; 2Huntington Medical Research Institutes, Pasadena, CA, USA.



13:50

576.

Brain Glycogen Detection in Pompe's Disease

Adrianus Van Den Bergh1, Dennis Klomp1, Jan Smeitink1, Ron Wevers1, Arend Heerschap1

1University Hospital Nijmegen, Nijmegen, Netherlands.



14:00

577.

Brain Neurochemical Abnormalities in Childhood Autism

S. D. Friedman1, D.W.W. Shaw1, A. A. Artru1, D. Echelard1, T. L. Richards1, S. Posse2, G. Dawson1, S. R. Dager1

1University of Washington, Seattle, WA, USA; 2Wayne State University, Detroit, MI, USA.



14:10

578.

Comparison of Regional Cerebral Metabolite Profiles in Two Mitochondrial Encephalomyopathies, MELAS and MERRF, using 1H MRSI

D.C. Shungu1, M. Sano1, W.S. Millar1, P. Kaufmann1, X. Mao1, A. Kwan1, S. DiMauro1, D.C. De Vivo1

1College of Physicians and Surgeons, Columbia University, New York, NY, USA.



14:20

579.

A Comparison of Proton MR Spectroscopic and Diffusion Tensor Brain MR Imaging in X-linked Adrenoleukodystrophy

Florian Eichler1, R. Itoh1, Peter B. Barker1, Elias Melhem2, Susumu Mori1, Peter C. Van Zijl1, Hugo W. Moser1, Gerald V. Raymond1

1Johns Hopkins University, Baltimore, MD, USA; 2Johns Hopkins University, Timonium, MD, USA.



14:30

580.

Predicting Clinical Outcome in Perinatal Asphyxia by MRI and MRS

Maria Zarifi1, Loukas Astrakas2, David Zurakowski2, Tina Poussaint2, Andre du Plessis2, Aria Tzika2

1Agia Sofia Children's Hospital, Athens, Atiiki, Greece; 2Children's Hospital, Harvard Medical School, Boston, MA, USA.



14:40

581.

Proton Spectroscopic Metabolite Signal Relaxation Times in Preterm Infants - a Prerequisite for Quantitative Spectroscopy in Infant Brain

Harald Kugel1, Bernhard Roth1, Oliver Schulte1, Frank Pillekamp1, Gabriele Benz-Bohm1, Klaus Lackner1

1University of Cologne, Köln, Germany.



14:50

582.

In Vivo Magnetic Resonance Spectroscopy in a Patient with Creatine Deficiency Syndrome: New Aspects on Mechanism of Creatine Uptake in Brain and Muscle

Thorsten Thiel1, Regina Ensenauer2, Jürgen Hennig1, Willy Lehnert2

1University Hospital Freiburg, Freiburg, Germany; 2University Children's Hospital, Freiburg, Germany;



15:00

583.

Quantitative Analysis of Brain Metabolites in 13 Patients with Sjögren-Larsson Syndrome

Marinette van der Graaf1, M.A.A.P. Willemsen1, J. J. Rotteveel1, Arend Heerschap1

1University Medical Center Nijmegen, Nijmegen, Netherlands.



15:10

584.

MRS in Homocystinuria: Severely Reduced mI in Neurologically Normal MTHFR Deficient Patients

Else Rubæk Danielsen1, Flemming Skovby1, Carsten Thomsen1

1Rigshospitalet, University of Copenhagen, Copenhagen, Denmark.



15:20

585.

MR Spectroscopic Changes in Pediatric Acute Hydrocephalus, Sub-Acute Hydrocephalus and Cortical Atrophy

Miriam Scadeng1, Rex Moats1, S Yamada1, Marvin D Nelson Jr1, J Gordon McComb1

1Children’s Hospital Los Angeles, Los Angeles, CA, USA.




CLINICAL SCIENCE FOCUS SESSION
MR Imaging of Female Pelvis

Hall 1


13:30 - 15:30
Chairs: Susan M. Ascher
Jane M. Hawnaur






13:30

586.

Dynamic MRI of the Pelvic Floor in Stress Urinary Incontinence: Technique, Normative Data in Continent Women, and Comparison with Physical Examination

Alan H. Stolpen1, Marc A. Hodroff1, Melody A. Denson1, Lizann Bolinger1, Bridget Zimmerman1, Bruce P. Brown1, Karl Kreder1

1University of Iowa, Iowa City, IA, USA.



13:40

587.

Pelvic Floor Anatomy in Stress Urinary Incontinence: MR Imaging with Endovaginal Coil

Jeong Kon Kim1, Kyoung-Sik Cho1, Hong Sik Kim1, Myoung Soo Choo1

1Asan Medical Center, University of Ulsan, Seoul, Korea.



13:50

588.

Magnetic Resonance Imaging of the Paravaginal Fascia and Urethra in Women with Urinary Stress Incontinence

Nandita Maria de Souza1, O J Daniels1, Andreanna Williams1, David James Larkman1, David John Gilderdale1

1Imperial College School of Medicine, Hammersmith Hospital, London, England, UK.



14:00

589.

Reproducibility of Serial MR Measurement of Female Sexual Arousal Response

Kenneth R Maravilla1, Yunyu Cao1, Patricia Garland1, Denise Echelard1, Julia R. Heiman1, Laura J. Hart1, Jean Kallhoff1, Barry Peterson2, Robert Weisskoff3

1University of Washington, Seattle, WA, USA; 2Pfizer Pharmaceutical; 3EPIX Medical Inc., Cambridge, MA, USA.



14:10

590.

The Application of a Quantitative Magnetisation Transfer Sequence in the Study of Placental Development

Damian Tyler1, Rachel Moore1, Stephen Ong1, Philip Baker1, Ian Johnson1, Penny Gowland1

1University of Nottingham, Nottingham, England, UK.



14:20

591.

Fetal Volumetry Based on 3D Reconstructions of 2D Single-Shot Fast Spin-Echo MR Data Sets

Rahel A Kubik-Huch1, Simon Wildermuth1, Luca Cettuzzi1, Annett Rake1, Burkhardt Seifert1, Rabih Chaoui1, Nino Teodorovic1, Borut Marincek1

1University Hospital Zürich, Zürich, Switzerland.



14:30

592.

Intra-voxel Incoherent Motion Measurements of Spiral Artery Function During Normal and Compromised Pregnancy.

Rachel Moore1, Stephen Ong1, Damian Tyler1, Philip Baker1, Ian Johnson1, Penny Gowland1

1Nottingham University, Nottingham, UK.



14:40

593.

Uterine Fibroid Embolization: Assessment of Treatment Response Using Extraslice Spin Tagging (EST) MRI

Klaus D. Hagspiel1, Alan H. Matsumoto1, Stuart Scott Berr1

1University of Virginia, Charlottesville, VA USA.



14:50

594.

Application of the VIBE (Volumetric Interpolated Breath-hold Examination) MR Technique to the Evaluation and Follow-up of Patients Undergoing Uterine Fibroid Embolization

Naoki Takahashi1, Vamsidhar Narra1, Brooke E Spencer1, David Hovsepian1

1Mallinckrodt Institute of Radiology, Washington University, St Louis, MO, USA.



15:00

595.

Improving the Specificity of Diagnosis of Ovarian Cancer Using Dynamic Contrast-Enhanced MRI (DCE-MRI)

Glen H Hall1, Stephen L Atkin2, Lindsay W Turnbull2

1University of Hull, Hull Royal Infirmary, Hull, East Yorkshire, UK; 2University of Hull, Hull, East Yorkshire, UK.



15:10

596.

Preoperative Staging of Endometrial Carcinoma: Accuracy of T2-Weighted Fast Spin Echo Sequence and Dynamic Gadolinium-Enhanced MR Imaging

Riccardo Manfredi1, Paoletta Mirk2, Tommasina Meloni, Rossella Lopez, Alessandro P Margariti, Antonia Testa, Giovanni Scambia, Pasquale Marano

1Rome, Italy; 2"A Gemelli" University Hospital, Rome, Italy.



15:20

597.

Evaluation of Fast Real IR Imaging in the Pelvis

Yuichi Yamashita1, Satoshi Sugiura2, Takashi Ishimori3, Satoru Nakano3, Yasutane Mori3, Motoomi Ohkawa3

1Toshiba Medical Systems Co.,Ltd., Kagawa Japan; 2Toshiba Corp, Medical R&D Center, Japan; 3Kagawa Medical University, Kagawa, Japan;







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