MR Spectroscopy of Human Neurological Disorders
Hall 4
Tuesday: 13:30 - 15:30
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999.
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Quantitative Magnetic Resonance Imaging (MRI) and Proton Magnetic Resonance Spectroscopic Imaging (MRSI) of Dorsolateral Prefrontal Cortex in Children with Fetal Alcohol Syndrome.
Bernadette M Cortese1, John H Hannigan1, Gregory J. Moore1
1Wayne State University, Detroit, MI, USA.
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1000.
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Evaluation of Changes in Brain Metabolite Levels in Acute Disseminated Encephalomyelitis: An In Vivo 1H MRS Study
Wei Huang1, Lidia Gabis1, Mirjana Savatic1, Terry M. Button1, Nicholas J. Lenn1
1State University of New York at Stony Brook, Stony Brook, NY, USA.
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1001.
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1HMRS of Blood and Brain in a Case of Rhizomelic Chondrodysplasia Punctata
Angèle Viola1, Brigitte Chabrol2, Francisca Vintila2, Sylviane Confort-Gouny1, Patrick Viout1, Jean-Philippe Ranjeva1, Farid Boubred2, Patrick Cozzone1
1Faculté de Médecine, Marseille, France; 2Hôpital la Timone, Marseille, France.
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1002.
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Entire Hemispheric Proton In Vivo MRS Examination of Sturge-Weber Syndrome at 3 T
Hee-Won Kim1, Angela P. Bruner1, Bernard L. Maria1, Katherine N. Scott1
1University of Florida, Gainesville, FL, USA.
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1003.
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Proton Spectroscopy in Tuberous Sclerosis Complex
Iain D Wilkinson1, William Mukonoweshuro1, Paul D Griffiths1
1University of Sheffield, Royal Hallamshire Hospital, Sheffield, England, UK.
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1004.
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Intracellular pH Measurements of the Whole Head and the Basal Ganglia in Chronic Hepatic Encephalopathy: A Phosphorus-31 MR Spectroscopy Study
Nayna Patel1, Daniel Forton2, Gavin Hamilton1, Glyn A Coutts3, Howard Christopher Thomas4, Simon David Taylor-Robinson2
1Hammersmith Hospital Campus, Imperial College School of Medicine, London, England, UK; 2Hammersmith Hospital Campus/St Mary's Hospital Campus, Imperial College School of Medicine, London, England, UK; 3Marconi Medical Systems, Hammersmith Hospital, Imperial College School of Medicine, London, England, UK; 4St Mary's Campus, Imperial College School of Medicine, London, England, UK.
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1005.
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Proton-Decoupled 31P MR Spectroscopic Imaging of Radiation-Induced Temporal Lobe Necrosis
David Yeung1, Yu-Leung Chan2, Heinz-Peter Schlemmer3, Sing-Fai Leung1, Peter Bachert3
1Prince of Wales Hospital, Shatin, Hong Kong, China; 2Chinese University of Hong Kong, Shatin, Hong Kong, China; 3German Cancer Research Centre, Heidelberg, Germany.
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1006.
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MR-Spectroscopy of the Spinal Cord of Professional Cyclists and
controls
Martin Büchert1, Carsten Altehoefer1
1University of Freiburg, Freiburg, Germany.
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1007.
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Abnormal 13C Glucose Metabolism in Patients with Chronic Hepatic Encephalopathy
Stefan Bluml1, Angel Moreno-Torres1, Brian Ross2
1Rudi Schulte Research Institute, Santa Barbara, CA, USA; 2Huntington Medical Research Institutes, Pasadena, CA, USA.
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1008.
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Long-term Brain Metabolic Alterations in Exogenous Cushing's Syndrome as Monitored by Proton Magnetic Resonance Spectroscopy
Abdesslem Khiat1, Céline Bard2, André Lacroix2, Martin Labelle1, Yvan Boulanger1
1Hôpital Saint-Luc du CHUM, Montréal, Québec, Canada; 2Hôtel-Dieu du CHUM, Montréal, Québec, Canada.
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1009.
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Proton Magnetic Resonance Chemical Shift Imaging(1H CSI)-directed Stereotactic Biopsy
Hyeon-Man Baik1, Byung-Chul Son1, Bo-Young Choe1, Tae-Suk Suh1, Hyoung-Koo Lee1, Kyung-Sub Shinn1
1Catholic University of Korea, Seoul, Korea.
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1010.
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Choline Imaging with PET and 2D-CSI in a Human Brain Astrocytoma
Medhi Adinehzadeh1, Raymond Poelstra1, Martin Jackob1, Joseph Mantil1, Jogeshwar Mukherje1, Brad Christian1, Bingshi Zhi1, Michael Kent1, Bilal Ezzeddine1
1Wallace-Kettering Neuroscience Institute, Kettering, OH, USA.
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MR Spectroscopy of Human Psychiatric Disorders
Hall 4
Tuesday: 13:30 - 15:30
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1011.
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Detection of Cerebral Gamma-aminobutyric Acid (GABA) in Biopolar Disorder Patients and Healthy Volunteers at 3T
Napapon Sailasuta1, Patrick Leroux2, Ralph Hurd1, Paul Wang3, N. Sachs4, Terrence Ketter4
1 G. E. Medical Systems Group, Fremont, CA USA; 2Palaiseau, France; 3Don Mills, Ontario Canada; 5Stanford University, Stanford, CA, USA.
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1012.
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No Significant Change of Brain Myo-Inositol is Observed in Bipolar Affective Disorder after Sodium Valproate Medication by In Vivo Proton MR Spectroscopy
Ren Hua Wu1, Peter H Silverstone1
1University of Alberta, University of Alberta Hospital, Edmonton, Alberta, Canada.
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1013.
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Neurochemical Correlates of Late-Life Major Depression
Anand Kumar1, Albert Michael Thomas1, Helen Lavretsky1, Arthur Toga1, Michael Mega1, Daniel Pham1, Kenneth Yue1, Amir Huda1, Talaignair Nagaraj Venkatraman1
1UCLA School of Medicine, Los Angeles, CA, USA.
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1014.
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Follow-up Investigation of Hippocampal Choline in Depression after ECT
Gabriele Ende1, Thomas S Obergriesser1, Wolfgang Weber-Fahr1, Fritz A Henn1
1Central Institute of Mental Health, Mannheim, Germany.
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1015.
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4.0 Tesla Measurements of N-acetylaspartate, Glutamate and Glutamine in the Anterior Cingulate and Thalamus of Schizophrenic Patients Pre and Post Treatment
J. Théberge1, D. J. Drost1, P. C. Williamson1, R. Bartha2, A K Malla1, Y. Al-Semaan1, R. Wj Neufeld1, R. S Menon2
1University of Western Ontario, London, ON, Canada; 2Robarts Research Institute, London, ON, Canada.
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1016.
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Membrane Phospholipid Metabolite Alterations in Prefrontal and Basal Ganglia Regions in Schizophrenia: An In Vivo 31P and 1H MRSI Study
Jeffrey A. Stanley1, Matcheri S. Keshavan1, Kanagasabai Panchalingam1, Richard J. McClure1, Jay W. Pettegrew1
1University of Pittsburgh, Western Psychiatric Institute & Clinic, Pittsburgh, PA, USA.
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1017.
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Focal and Generalized Membrane Phospholipid Metabolite Alterations in Child and Adolescent Offspring of Schizophrenia and Schizoaffective Disorder Subjects: An In Vivo 31P MRSI Study
Jeffrey A. Stanley1, Jay W. Pettegrew1, Kanagasabai Panchalingam1, Richard J. McClure1, Keith Harenski1, Debra M. Montrose1, Matcheri S. Keshavan1
1University of Pittsburgh, Western Psychiatric Institute & Clinic, Pittsburgh, PA, USA.
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1018.
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1H MRSI of the Cerebellum and Pons: Metabolite Distribution in Controls and Schizophrenics
Gabriele Ende1, Petra Hubrich-Ungureanu1, Nina Kämmerer1, Fritz A Henn1
1Central Institute of Mental Health, Mannheim, Germany.
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1019.
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Acute Fire-related Posttraumatic Stress Disorder: MR Imaging and 1H MR Spectroscopic Findings
Myung Kwan Lim1, Jeong Seop Lee1, Chang Hae Suh1
1Inha University College of Medicine, Incheon, South Korea.
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1020.
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Study of Systemic Lupus Erythematosus: Correlation of Clinical Findings with MRI, MRS and SPECT.
Preeti Sahota1, Mahesh Kumar1, Rohini Handa1, C.S Bal1, M. Gulati1, B.M Tripathi1, N.R Jagannathan1, J.P Wali1
1All India Institute of Medical Sciences, Ansari Nagar, New Delhi India.
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1021.
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Metabolic Changes in the Brain of Depressive Patients
Stephan Gruber1, Richard Frey1 Vladimir Mlynarik1, Angela Heiden1, Siegfried Kasper1, Ewald Moser1
1University of Vienna, Vienna, Austria.
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MR Spectroscopy of Animal Brain
Hall 4
Tuesday: 13:30 - 15:30
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1022.
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PRESS Sequences with Very Short Echo Times using Asymmetric RF Pulses. Application to the Rat Brain In Vivo.
Christian Geppert1, Wolfgang Dreher1, Dieter Leibfritz1
1University of Bremen, Bremen, Germany.
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1023.
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High Resolution Fast Spectroscopic Imaging of Water 1H Resonance in Rat Brain
Weiliang Du1, Xiaobing Fan, Marta Zamora, Gregory Karczmar
1University of Chicago, Chicago, IL, USA.
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1024.
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Rapid Estimation of Cerebral Glucose Metabolism in the Rat
David Marshall Cohen1, Michael Quast2, Jingna Wei2, Xiaolian Gao3, E. O'Brian Smith1, Louis Sokoloff4
1Baylor College of Medicine, Houston, TX, USA; 2University of Texas Medical Branch at Galveston, Galveston, TX, USA; 3University of Houston, Houston, TX, USA; 4National Institute of Mental Health, National Institutes of Health, Bethesda, MD, USA.
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1025.
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17O Relaxation Time and NMR Sensitivity of Cerebral Water and Their Field Dependence
Xiao-Hong Zhu1, Hellmut Merkle1, Jaehwan Kwag1, Kamil Ugurbil1, Wei Chen1
1University of Minnesota, Minneapolis, MN, USA.
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1026.
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Choline Transport and Metabolism in the Aging Rat Brain
Rachel Katz-Brull1, Alexei R. Koudinov1, Hadassa Degani1
1Weizmann Institute of Science, Rehovot, Israel.
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1027.
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Longitudinal Proton MRS Study of the Metabolic Changes During Lesion Progression in Experimental Allergic Encephalomyelitis
Mahaveer Degaonkar1, Rama Jayasundar1, N. R. Jagannathan1
1All India Institute of Medical Sciences, New Delhi, India.
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1028.
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Brain and Immune Changes in Response to Psychosocial Stress Are Reversed by Tianeptine
Thomas Michaelis1, G. De Biurrun2, Tokuko Watanabe3, Jens Frahm1, M. van Kampen4, E. Fuchs4, C. Hiemke5, B. van't Hart6, Brok H6, A. Bartolumuci7, C. Muñoz8
1Biomedisinische NMR Forschungs GmbH, MPI für biophysiklische Chemie, Göttingen, Germany; 2Biomedizinische NMR Forschungs GmbH, Göttingen, Germany; 3Tokyo University of Fisheries, Tokyo, Japan; 4DPZ, Göttingen, Germany; 5University Mainz, Mainz, Germany; 6BPRC, Rijswijk, The Netherlands; 7University Parma, Parma, Italy; 8I.R.I. Servier, Courbevoie, France.
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1029.
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In Vivo 2D 1H-MRS of Metabolic Changes Following Transient Focal Cerebral Ischemia in the Rat
Florence Delmas1, Wouter B. Veldhuis2, Boudewijn Van der Sanden2, Brigitte Gillet3, Jean-Claude Beloeil3, Klaas Nicolay4
1CNRS, Gif-sur-Yvette, France; 2Image Sciences Institute, Utrecht, Netherlands; 3ICSN CNRS, Gif/Yvette, France; 4University Utrecht, Utrecht, Netherlands.
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1030.
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Effects of a Glutamate Transport Inhibitor on Brain Metabolism
Caroline Rae1, Charbel E-H Moussa1, William A Bubb1, Vladimir Balcar1
1University of Sydney, Sydney, NSW, Australia.
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1031.
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GABAergic and Glutamatergic Neurotransmitter Cycling in the Rat Cortex
Anant B. Patel1, Robin A. de Graaf1, Graeme F. Mason1, Gary W. Cline1, Vincent Lebon1, Gerald I. Shulman1, Robert G. Shulman1, Douglas L. Rothman1, Kevin L. Behar1
1Yale University School of Medicine, New Haven, CT, USA.
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1032.
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13C Spectroscopic Evidence for Regionally Specific Alterations in Neuronal Activity under General Anesthesia
P. N. Venkatasubramanian1, Alice M. Wyrwicz1
1Evanston Northwestern Healthcare, Evanston, IL, USA.
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1033.
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From Metabolic Neurotoxicity to Hypoxic Neuroprotection: An MRS Study of Cyclosporine Role in Rat Brain.
Natalie Serkova1, Paul Donohoe2, Sven Gottschalk1, Carsten Hainz1, Uwe Christians2, Dieter Leibfritz1
1University of Bremen, Bremen, Germany; 2University of California San Francisco, San Francisco, CA, USA.
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1034.
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Development of High Field Proton Spectroscopic Imaging for the Mouse Brain
Gerald B. Matson1, T. C. Hill1, V. Govindaraju1
1Department of Veterans Affairs Medical Center, University of California San Francisco, San Francisco, CA, USA.
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1035.
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Temporal and Regional Changes in NAA in the Pathogenesis of Spongiform Encephalopathy
Y-L Chung1, J Barr2, J R Fraser2, J D Bell1
1Imperial College School of Medicine, Hammersmith Hospital, London, U.K.; 2Institute for Animal Health, Edinburgh, UK.
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