Monday am opening session clyde Auditorium 07: 45 08: 20 Welcome and Medal Presentations



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MR Spectroscopy Applications

Forth


10:30 - 12:30
Chairs: Ognen A.C. Petroff
William D. Rooney






10:30

199.

In Vivo Detection of Gene Expression in Liver by 31P Nuclear Magnetic Resonance Spectroscopy Employing Creatine Kinase as a Marker Gene

Zhou R.1, A. Auricchio1, J. M. Wilson1, Jerry Glickson1

1University of Pennsylvania, Philadelphia, PA, USA.



10:42

200.

In Vivo 31P Evaluation of Cold/Solid Thyroid Nodules

Rama Jayasundar1

1All India Institute of Medical Sciences, New Delhi, India.



10:54

201.

Identification of Hydroxyl Ion in Bone Mineral Using Solid State Two Dimensional 1H–31P Heteronuclear Correlation NMR Spectroscopy

Gyunggoo Cho1, Jerome Ackerman1

1Massachusetts General Hospital, Harvard Medical School, Charlestown, MA, USA.



11:06

202.

Simultaneous Water and Fat Suppression in Breast MRS Using Spectral/Spatial PRESS

Lawrence Ryner1, Louis Lauzon2

1The National Research Council, Winnipeg, MB, Canada; 2GE Yokogawa Medical Systems, Tokyo Japan.



11:18

203.

Effects of High versus Low Fatty Acid Levels During Hyperinsulinemia by Measuring Relative Intromycellular and Extramyocellular Triglyceride Levels with Proton Magnetic Resonance Spectroscopy in Normal Subjects

Susan K. Lemieux1, Guenther H. Boden2

1WVU Health Sciences Center, Morgantown, WV, USA; 2Temple University, School of Medicine, Philadelphia, PA, USA.



11:30

204.

The Use of [2-13C] Acetate to Determine the Pathway for Neurotransmitter Glutamate Repletion in the Human Brain

Vincent Lebon1, Kitt F. Petersen1, Gary W. Cline1, Jun Shen2, Graeme F. Mason1, Sylvie Dufour1, Kevin L. Behar1, Gerald I. Shulman1, Douglas L. Rothman1

1Yale University, School of Medicine, New Haven, CT, USA; 2Nathan S. Kline Institute, Orangeburg, NY, USA.



11:42

205.

In Vivo NMR Measurement of TCA Cycle Rate Alteration Following 3NP intoxication

Pierre-Gilles Henry1, Vincent Lebon2, Francoise Vaufrey1, Emmanuel Brouillet1, Philippe Hantraye1, Gilles Bloch1

1CEA-SHFJ, Orsay, France; 2Yale University, Medicine, School of Medicine, New Haven, CT, USA.



11:54

206.

Assessment of Hepatic Carbohydrate Metabolism in vivo by 3D-localized 13C NMR: The Role of fructose-2,6-bisphosphate in Regulation of Glucose Fluxes in Mice

In-Young Choi1, Chaodong Wu1, David A. Okar1, Alex J. Lange1, Rolf Gruetter1

1University of Minnesota, Minneapolis, MN, USA.



12:06

207.

13C MRS Correlates with Clinical Severity of Hepatic Encephalopathy

BD Ross1, A Moreno-Torres1, J-H Hwang1, J Korula2, C Lowe2, S Bluml1

1Huntington Medical Research Institutes, Pasadena, CA, USA; 2University Hospital, University of Southern California, Los Angeles, CA USA.



12:18

208.

Correlation between Cerebral Proton MRS and Psychometry in Patients with Chronic Hepatitis C Infection

Daniel M Forton1, Joanna M Allsop1, Glyn A Coutts1, Nicholas Hargarden Dr2, Howard C Thomas3, Simon D. Taylor-Robinson3

1Imperial College School of Medicine, Hammersmith Hospital, London, UK; 2CDR Limited, Reading, Berkshire, England, UK; 3Imperial College School of Medicine, St Mary's Hospital, London, UK.




Spectroscopic Quantitation

Alsh


10:30 - 12:30
Chairs: Thomas Ernst
Danielle Graveron-Demilly






10:30

209.

A Unified Comparison of Filtering Approaches to Water Peak Suppression in MRS

Leentje Vanhamme1, Alain Coron2, Paul Van Hecke1, Jean-Pierre Antoine1, Sabine Van Huffel1

1Katholieke Universiteit Leuven, Leuven, Belgium; 2Delft University of Technology, Delft, The Netherlands.



10:42

210.

In vivo 13C NMR Measurement of Total Brain Glycogen Concentrations in the Conscious Rat

In-Young Choi1, Rolf Gruetter1

1University of Minnesota, Medical School, Minneapolis, MN, USA.



10:54

211.

Comparison of Two non-Invasive Approaches for Determination of Gluconeogenesis: In vitro 2H versus In vivo 13C NMR Spectroscopy.

Martin Krssak1, Harald Stingl1, Eva Rosian2, Olaf Kunert2, Klaus Zanger2, Werner Waldhäusl1, Ernst Haslinger2, Michael Roden1

1University of Vienna, Wien, Austria; 2University of Graz, Graz, Austria.



11:06

212.

T2 Relaxation Study of Water, N-acetylaspartate (NAA)and Creatine (Cr) in Human Brains Using Hahn and Carr-Purcell Spin-Echoes at 4T and 7T

Shalom Michaeli1, Michael Garwood1, Xiao-Hong Zhu1, Lance DelaBarre1, Gregor Adriany1, Peter Andersen1, Hellmut Merkle1, Kamil Ugurbil1, Wei Chen1

1University of Minnesota, Minneapolis, MN, USA.



11:18

213.

Phosphocreatine has shorter T2* than Creatine in vivo

Yong Ke1, Bruce M Cohen1, Fuyuki Hirashima1, Leanne Nassar1, Perry Renshaw1

1McLean Hospital, Harvard Medical School, Belmont, MA, USA.



11:30

214.

Quantification of 1H NMR Spectra of the Human Brain using LCModel and Spin Simulations at 7 Tesla

Ivan Tkac1, Joonmo Kim1, Kamil Ugurbil1, Rolf Gruetter1

1University of Minnesota, Minneapolis, MN, USA.



11:42

215.

A New Method of Determining Spin-Lattice Relaxation Times and Rate Coefficients for a Chemically Exchanging System Using the One-Pulse Experiment

C. Galban1, R.G.S. Spencer1

1NIH/National Institute on Aging, Baltimore, MD, USA.



11:54

216.

A Rapid Method For Correction of CSF Partial Volume in Quantitative Proton MR Spectroscopic Imaging

Alena Horska1, Vince Calhoun1, Peter B. Barker1

1Johns Hopkins University, Baltimore, MD, USA.



12:06

217.

Quantitative Spin Echo 31P Spectroscopic Imaging in Human Brain: Determination of the Free Energy of ATP Hydrolysis

Hoby Hetherington1, J. H. Lee2, M. K. Sammi2, J. W. Pan3

1Yeshiva University, Albert Einstein College of Medicine, Bronx, NY, USA; 2Brookhaven National Laboratory, Upton, NY, USA; 3Albert Einstein College of Medicine, Bronx, NY, USA.



12:18

218.

The In Vivo Detection of Myo-Inosital Using Double Quantum Coherence Filtering at 3T

H. Kim1, P. S. Allen1

1University of Alberta, Edmonton, AL, Canada.




GOLD CORPORATE MEMBER LUNCHTIME SYMPOSIUM

Philips Medical Systems

The Magic of Intera

Argyll (Moat House)

12:30 – 13:30

BASIC SCIENCE FOCUS SESSION (WITH POSTERS)

fMRI: Signal Modeling and New Techniques

Clyde Auditorium

Tuesday: 13:30 - 15:30



Chairs: Richard B. Buxton
Robert Turner


Please see page 179 for details.



BASIC SCIENCE FOCUS SESSION (WITH POSTERS)

Elastography

Hall 2

Tuesday: 13:30 - 15:30



Chairs: John B. Weaver
Michael H. Buonocore


Please see page 222 for details.



CLINICAL SCIENCE FOCUS SESSION
Myocardial Viability

Lomond


13:30 - 15:30
Chairs: Robert M. Judd
Robert J. Herfkens






13:30

219.

Extent of Hyperenhancement After Myocardial Infarction Depends Upon Timing After Contrast

C. Joon Choi1, Joseph M. DiMaria1, Frederick H. Epstein1, Jennifer R. Hunter1, Christopher M. Kramer1

1University of Virginia, Charlottesville, VA, USA.



13:40

220.

Diagnostic Value of Wall Motion, Perfusion, and Delayed Hyperenhancement in Emergency Room Evaluation of Chest Pain

Raymond Yan Kwong1, Anthony Homer Aletras1, Suresh Rekhraj1, Andrew Ernest Arai1

1National Institutes of Health, Bethesda, MD, USA.



13:50

221.

Delayed myocardial Enhancement - Correlation to Thallium SPECT and FDG PET

Kirsi Lauerma1, Helena Hänninen1, Tuula Janatuinen2, Kari Virtanen1, Sami Soljanlahti1, Pekka Niemi2, Juhani Knuuti2, Hannu J. Aronen1

1Helsinki University Hospital, Helsinki, Finland; 2Turku University, Turku, Finland.



14:00

222.

Delayed Myocardial Contrast Enhancement in Patients with Acute Myocardial Infarction: Comparison with Thallium-201 SPECT Imaging

Kakuya Kitagawa1, Hajime Sakuma2, Tadanori Hirano1, Kan Takeda2, Ichiro Kadoya1, Katsutoshi Makino1, Shinya Okamoto1

1Matsusaka Central Hospital, Matsusaka, Mie Japan; 2Mie University School of Medicine, Tsu, Mie Japan.



14:10

223.

Diffusion Tensor MRI Mapping The Fiber Architecture of Myocardium Post Infarction – Preliminary Experience in Correlation with Viability Map of Tl201-SPECT and Delay-enhanced MRI

Ming-Ting Wu1, Wen-Yih Tseng2, Chun-Peng Liu3, Van Wedeen4, Timothy Reese5, Huay-Ben Pan1, Chien-Fang Yang1

1Kaohsiung Veterans General Hospital, School of Medicine, National Yang Ming University, Kaohsiung, Taiwan; 2Center for Optoelectronic Biomedicine, Taipei, Taiwan; 3Department of Medicine; 4Massachusetts General Hospital, Charlestown, HA, USA; 5Harvard University, Boston, MA, USA.



14:20

224.

Differentiation of Viable and Non-Viable Myocardium: Comparison of Gd-Based Extracellular and Bloodpool Contrast Materials versus Manganese-Based Contrast Materials in a Rat Myocardial Infarction Model

Sebastian Flacke1, John Stacy Allen1, Jonathan M Chia1, Max Adams2, MP Periasamy2, I Kofi Adzamli2, Christine H Lorenz1

1Washington University, St. Louis, MO, USA; 2Mallinckrodt Inc., St. Louis, MO, USA.



14:30

225.

Imaging of Myocardial Infarction: Comparison of Magnevist and Gadophrin III in Rabbits

Jörg Barkhausen1, Wolfgang Ebert2, Claudia Heyer2, Jorg F Debatin1, Hanns-Joachim Weinmann2

1University Hospital Essen, Essen, Germany; 2Schering AG, Berlin, Germany.



14:40

226.

Delayed-Enhancement MRI Reveals Myocardial Fibrosis in Patients with Symptomatic Hypertrophic Cardiomyopathy

Scott D. Flamm1, Rollo P. Villareal1, Ramesh Hariharan2, Raja Muthupillai3, Ali G. Massumi1, James M. Wilson1

1Texas Heart Institute, Houston, TX, USA ; 2Baylor College of Medicine, Houston, TX, USA; 3Philips Medical Systems, St. Luke's Episcopal Hospital, Houston, TX, USA.



14:50

227.

Delayed Hyperenhancement Detects Myocardial Abnormalities

Ralf Wassmuth1, Anthony H Aletras1, David A Begley1, Karen E Bove Bettis1, Kwabena O Agyeman1, Lameh Fananapazir1, Andrew E Arai1

1National Institutes of Health, Bethesda, MD, USA.



15:00

228.

Assessment of Myocardial Fibrosis in Hypertrophic Cardiomyopathy with First Pass and Delayed T1 Enhancement

P Sipola1, K Lauerma2, J T Kuikka1, E Vanninen1, K Peuhkurinen1, P Jääskeläinen1, M Laakso1, H Manninen1, J Kuusisto1, H J Aronen1

1Kuopio University Hospital, Kuopio, Finland; 2Helsinki University Central Hospital, Helsinki, Finland.



15:10

229.

Global Measurement of the Myocardial Perfusion Index: Application to the Assessment of the Incomplete Gd-DTPA Clearance in Rest/Stress Studies of Cardiac Perfusion

A Radjenovic1, J P Ridgway1, T N Bloomer1, S Plein1, D M Higgins1, J FM Meaney1, A Kassner2, U M Sivananthan1

1Leeds General Infirmary, Leeds, UK; 2Philips Medical Systems, UK, Leeds, UK.



15:20

230.

Phase Sensitive Inversion Recovery for Detecting Myocardial Infarction using Gd-DTPA Delayed Hyper-Enhancement

Peter Kellman1, Andrew E. Arai1, Elliot R. McVeigh1, Anthony H. Aletras1

1National Institutes of Health, Bethesda, MD, USA.




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