Personal Research Database Bibliometric

Full Text: 2012\Wor J Gas18, 3156.pdf

Abstract: AIM: To evaluate the safety and effectiveness of two-stage vs single-stage management for concomitant gallstones and common bile duct stones. METHODS: Four databases, including PubMed, Embase, the Cochrane Central Register of Controlled Trials and the Science Citation Index up to September 2011, were searched to identify all randomized controlled trials (RCTs). Data were extracted from the studies by two independent reviewers. The primary outcomes were stone clearance from the common bile duct, postoperative morbidity and mortality. The secondary outcomes were conversion to other procedures, number of procedures per patient, length of hospital stay, total operative time, hospitalization charges, patient acceptance and quality of life scores. RESULTS: Seven eligible RCTs [five trials (n = 621) comparing preoperative endoscopic retrograde cholangiopancreatography (ERCP)/endoscopic sphincterotomy (EST) + laparoscopic cholecystectomy (LC) with LC + laparoscopic common bile duct exploration (LCBDE); two trials (n = 166) comparing postoperative ERCP/EST + LC with LC + LCBDE], composed of 787 patients in total, were included in the final analysis. The meta-analysis detected no statistically significant difference between the two groups in stone clearance from the common bile duct [risk ratios (RR) = -0.10, 95% confidence intervals (CI): -0.24 to 0.04, P = 0.17], postoperative morbidity (RR = 0.79, 95% CI: 0.58 to 1.10, P = 0.16), mortality (RR = 2.19, 95% CI: 0.33 to 14.67, P = 0.42), conversion to other procedures (RR = 1.21, 95% CI: 0.54 to 2.70, P = 0.39), length of hospital stay (MD = 0.99, 95% CI: -1.59 to 3.57, P = 0.45), total operative time (MD = 12.14, 95% CI: -1.83 to 26.10, P = 0.09). Two-stage (LC + ERCP/EST) management clearly required more procedures per patient than single-stage (LC + LCBDE) management. CONCLUSION: Single-stage management is equivalent to two-stage management but requires fewer procedures. However, patient’s condition, operator’s expertise and local resources should be taken into account in making treatment decisions. (C) 2012 Baishideng. All rights reserved.

Keywords: 1000 Laparoscopic Cholecystectomies, Acceptance, Analysis, Cholecystectomy, Citation, Cochrane, Common Bile Duct Stones, Comparing 2-Stage, Confidence, Confidence Intervals, Cost-Effective Management, Databases, Effectiveness, Embase, Endoscopic Retrograde Cholangiopancreatography, Endoscopic Retrograde Cholangiopancreatography, Endoscopic Sphincterotomy, Exploration, Gallstones, Hospital, Hospital Stay, Hospitalization, Intervals, Laparoscopic, Laparoscopic Cholecystectomy, Laparoscopic Common Bile Duct Exploration, Length, Life, Local, Management, Meta-Analysis, Metaanalysis, Methods, Morbidity, Mortality, Operative, Outcomes, P, Patients, Perioperative Cholangiography, Postoperative, Postoperative Morbidity, Preoperative, Primary, Procedures, Prospective Multicenter, Prospective Randomized-Trial, Pubmed, Quality, Quality Of, Quality of Life, Randomized, Randomized Controlled Trials, Resources, Rights, Risk-Factors, Safety, Science, Science Citation Index, T-Tube Drainage, Treatment

? Cheng, Y., Xiong, X.Z., Wu, S.J., Lu, J., Lin, Y.X., Cheng, N.S. and Wu, T.X. (2012), Carbon dioxide insufflation for endoscopic retrograde cholangiopancreatography: A meta-analysis and systematic review. World Journal of Gastroenterology, 18 (39), 5622-5631.

Full Text: 2012\Wor J Gas18, 5622.pdf

Abstract: AIM: To assess the safety and efficacy of carbon dioxide (CO2) insufflation during endoscopic retrograde cholangiopancreatography (ERCP). METHODS: the Cochrane Library, Medical Literature Analysis and Retrieval System Online, Excerpta Medica Database, Science Citation Index Expanded, Chinese Biomedical Literature Database, and references in relevant publications were searched up to December 2011 to identify randomized controlled trials (RCTs) comparing CO2 insufflation with air insufflation during ERCP. The trials were included in the review irrespective of sample size, publication status, or language. Study selection and data extraction were performed by two independent authors. The meta-analysis was performed using Review Manager 5.1.6. A random-effects model was used to analyze various outcomes. Sensitivity and subgroup analyses were performed if necessary. RESULTS: Seven double-blind RCTs involving a total of 818 patients were identified that compared CO2 insufflation (n = 404) with air insufflation (n = 401) during ERCP. There were a total of 13 post-randomization dropouts in four RCTs. Six RCTs had a high risk of bias and one had a low risk of bias. None of the RCTs reported any severe gas-related adverse events in either group. A meta-analysis of 5 RCTs (n = 459) indicated that patients in the CO2 insufflation group had less post-ERCP abdominal pain and distension for at least 1 h compared with patients in the air insufflation group. There were no significant differences in mild cardiopulmonary complications [risk ratio (RR) = 0.43, 95% CI: 0.07-2.66, P = 0.36], cardiopulmonary (e.g., blood CO2 level) changes [standardized mean difference (SMD) = -0.97, 95% CI: -2.58-0.63, P = 0.23], cost analysis (mean difference = 3.14, 95% CI: -14.57-20.85, P = 0.73), and total procedure time (SMD = -0.05, 95% CI: -0.26-0.17, P = 0.67) between the two groups. CONCLUSION: CO2 insufflation during ERCP appears to be safe and reduces post-ERCP abdominal pain and discomfort. (C) 2012 Baishideng. All rights reserved.

Keywords: Abdominal, Abdominal Pain, Air, Air Insufflation, Analyses, Analysis, Authors, Bias, Blood, Carbon, Carbon Dioxide, Carbon Dioxide Insufflation, Cardiopulmonary, Changes, Chinese, Citation, CO₂, Complications, Cost, Cost Analysis, Data, Double-Blind, Efficacy, Endoscopic Retrograde Cholangiopancreatography, ERCP, Events, Extraction, Language, Literature, Low Risk, Medical, Meta-Analysis, Metaanalysis, Methods, Model, Outcomes, P, Pain, Patients, Procedure, Publication, Publications, Random Effects Model, Randomized, Randomized Controlled Trials, References, Review, Rights, Risk, Safety, Sample Size, Science, Science Citation Index, Science Citation Index Expanded, Selection, Size, Statement, Systematic Review, Trial

? Xiong, J.J., Altaf, K., Javed, M.A., Huang, W., Mukherjee, R., Mai, G., Sutton, R., Liu, X.B. and Hu, W.M. (2012), Meta-analysis of laparoscopic vs open liver resection for hepatocellular carcinoma. World Journal of Gastroenterology, 18 (45), 6657-6668.

Full Text: 2012\Wor J Gas18, 6657.pdf

Keywords: Authors, Bleeding, Blood, Blood Loss, Blood Transfusion, Case-Matched Analysis, Cirrhosis, Citation, Clinical-Trials, Cochrane Collaboration, Collaboration, Complications, Data, Developing, Effects, Efficacy, Evidence, Failure, Hepatectomy, Hepatectomy, Hepatic Resection, Hepatocellular Carcinoma, Hospital, Hospital Stay, Incidence, Intraoperative Blood Loss, Intraoperative Ultrasonography, Laparoscopic, Laparoscopy, Liver, Liver Failure, MEDLINE, Meta Analysis, Meta-Analysis, Metaanalysis, Methods, Models, Mortality, Open, Open Liver Resection, Operation, Operative, Outcomes, P, Patients, Perioperative Blood-Transfusion, Postoperative, Pubmed, Randomized, Randomized Controlled Trials, Recurrence, Reporting, Requirement, Review, Rights, Safety, Science, Science Citation Index, Science Citation Index Expanded, Software, Surgery, Survival, Term, Transfusion, Tumor, United Kingdom

? Yu, X.F., Wang, Y.Q., Zou, J. and Dong, J. (2012), A meta-analysis of the effects of energy intake on risk of digestive cancers. World Journal of Gastroenterology, 18 (48), 7362-7370.

Full Text: 2012\Wor J Gas18, 7362.pdf

Abstract: AIM: To quantitatively assess the relationship between energy intake and the incidence of digestive cancers in a meta-analysis of cohort studies. METHODS: We searched MEDLINE, EMBASE, Science Citation Index Expanded, and the bibliographies of retrieved articles. Studies were included if they reported relative risks (RRs) and corresponding 95% CIs of digestive cancers with respect to total energy intake. When RRs were not available in the published article, they were computed from the exposure distributions. Data were extracted independently by two investigators and discrepancies were resolved by discussion with a third investigator. We performed fixed-effects meta-analyses and meta-regressions to compute the summary RR for highest versus lowest category of energy intake and for per unit energy intake and digestive cancer incidence by giving each study-specific RR a weight that was proportional to its precision. RESULTS: Nineteen studies consisting of 13 independent cohorts met the inclusion criteria. The studies included 995 577 participants and 5620 incident cases of digestive cancer with an average follow-up of 11.1 years. A significant inverse association was observed between energy intake and the incidence of digestive cancers. The RR of digestive cancers for the highest compared to the lowest caloric intake category was 0.90 (95% CI 0.81-0.98, P < 0.05). The RR for an increment of 239 kcal/d energy intake was 0.97 (95% CI 0.95-0.99, P < 0.05) in the fixed model. In subgroup analyses, we noted that energy intake was associated with a reduced risk of colorectal cancer (RR 0.90, 95% CI 0.81-0.99, P < 0.05) and an increased risk of gastric cancer (RR 1.19, 95% CI 1.08-1.31, P < 0.01). There appeared to be no association with esophageal (RR 0.96, 95% CI 0.86-1.07, P > 0.05) or pancreatic (RR 0.79, 95% CI 0.49-1.09, P > 0.05) cancer. Associations were also similar in studies from North America and Europe. The RR was 1.02 (95% CI 0.79-1.25, P> 0.05) when considering the six studies conducted in North America and 0.87 (95% CI 0.77-0.98, P < 0.05) for the five studies from Europe. CONCLUSION: Our findings suggest that high energy intake may reduce the total digestive cancer incidence and has a preventive effect on colorectal cancer. (C) 2012 Baishideng. All rights reserved.

Keywords: Analyses, Association, Bibliographies, Body-Mass Index, Cancer, Cancer Prevention, Citation, Cohort, Colon-Cancer, Colorectal Cancer, Colorectal-Cancer, Criteria, Diet, Dietary Restriction, Digestive Cancer, Effects, Embase, Energy, Energy Intake, Europe, Exposure, Follow-Up, Gastric Cancer, Hawaii Japanese Men, Incidence, MEDLINE, Meta Analysis, Meta-Analysis, Metaanalysis, Methods, Model, North, North America, P, Physical-Activity, Precision, Rectal-Cancer, Rights, Risk, Risks, Science, Science Citation Index, Science Citation Index Expanded, Term Calorie Restriction, Upper Aerodigestive Tract, World-War-II

? Moon, S.H. and Kim, M.H. (2013), Prophecy about post-endoscopic retrograde cholangiopancreatography pancreatitis: From divination to science. World Journal of Gastroenterology, 19 (5), 631-637.

Full Text: 2013\Wor J Gas19, 631.pdf

Abstract: One unresolved issue of endoscopic retrograde cholangiopancreatography (ERCP) is post-ERCP pancreatitis (PEP), which occurs in up to 40% of patients. Identification of risk factors for PEP is especially important in the field of ERCP practice because it may assist physicians in taking protective measures in situations with high risk. A decade ago, Freeman et al meticulously evaluated a large number of potentially relevant risk factors for PEP, which can be divided into patient-related and procedure-related issues. In this commentary, we summarize this classic article and reevaluate the risk factors for PEP from the current point of view. This is followed by assessment of strategies for prevention of PEP that can be divided into mechanical and pharmacologic methods. (C) 2013 Baishideng. All rights reserved.

Keywords: Assessment, Biliary Cannulation, Common Bile-Duct, Difficult Cannulation, Endoscopic Retrograde Cholangiopancreatography, Ercp, Ercp Pancreatitis, Field, High-Risk Patients, Methods, Needle-Knife Fistulotomy, Nonsteroidal Antiinflammatory Drugs, Nonsteroidal Antiinflammatory Drugs, Pancreatic Stents, Pancreatitis, Patients, Physicians, Post-Endoscopic Retrograde Cholangiopancreatography Pancreatitis, Practice, Prevention, Prevention of Post-Endoscopic Retrograde Cholangiopancreatography Pancreatitis, Prospective Multicenter, Randomized Controlled-Trials, Rights, Risk, Risk Factor, Risk Factors, Science, Stent Placement

? Xiong, J.J., Altaf, K., Javed, M.A., Nunes, Q.M., Huang, W., Mai, G., Tan, C.L., Mukherjee, R., Sutton, R., Hu, W.M. and Liu, X.B. (2013), Roux-en-Y versus Billroth I reconstruction after distal gastrectomy for gastric cancer: A meta-analysis. World Journal of Gastroenterology, 19 (7), 1124-1134.

Full Text: 2013\Wor J Gas19, 1124.pdf

Abstract: AIM: To conduct a meta- analysis to compare Rouxen- Y (R-Y) gastrojejunostomy with gastroduodenal Billroth I (B-I) anastomosis after distal gastrectomy (DG) for gastric cancer. METHODS: A literature search was performed to identify studies comparing R-Y with B-I after DG for gastric cancer from January 1990 to November 2012 in MEDLINE, Embase, Science Citation Index Expanded and the Cochrane Central Register of Controlled Trials in the Cochrane Library. Pooled odds ratios (OR) or weighted mean differences (WMD) with 95% CI were calculated using either fixed or random effects model. Operative outcomes such as operation time, intraoperative blood loss and postoperative outcomes such as anastomotic leakage and stricture, bile reflux, remnant gastritis, reflux esophagitis, dumping symptoms, delayed gastric emptying and hospital stay were the main outcomes assessed. Meta-analyses were performed using RevMan 5.0 software (Cochrane library). RESULTS: Four randomized controlled trials (RCTs) and 9 non-randomized observational clinical studies (OCS) involving 478 and 1402 patients respectively were included. Meta-analysis of RCTs revealed that R-Y reconstruction was associated with a reduced bile reflux (OR 0.04, 95% CI: 0.01, 0.14; P < 0.00 001) and remnant gastritis (OR 0.43, 95% CI: 0.28, 0.66; P = 0.0001), however needing a longer operation time (WMD 40.02, 95% CI: 13.93, 66.11; P = 0.003). Meta-analysis of OCS also revealed R-Y reconstruction had a lower incidence of bile reflux (OR 0.21, 95% CI: 0.08, 0.54; P = 0.001), remnant gastritis (OR 0.18, 95% CI: 0.11, 0.29; P < 0.00 001) and reflux esophagitis (OR 0.48, 95% CI: 0.26, 0.89; P = 0.02). However, this reconstruction method was found to be associated with a longer operation time (WMD 31.30, 95% CI: 12.99, 49.60; P = 0.0008). CONCLUSION: This systematic review point towards some clinical advantages that are rendered by R-Y compared to B-I reconstruction post DG. However there is a need for further adequately powered, welldesigned RCTs comparing the same. (C) 2013 Baishideng. All rights reserved.

Keywords: Adenocarcinoma, Analysis, Anastomotic Leakage, Billroth I, Blood, Blood Loss, Cancer, Citation, Clinical, Clinical Studies, Distal Gastrectomy, Duodenogastric Reflux, Effects, Gastric Cancer, Hospital, Hospital Stay, Incidence, Intraoperative Blood Loss, Literature, MEDLINE, Meta Analysis, Meta-Analysis, Metaanalysis, Methods, Model, Observational, Operation, Outcomes, P, Patients, Postoperative, Quality-Of-Life, Random Effects Model, Randomized, Randomized Controlled Trials, Rat, Reconstruction, Remnant Gastritis, Review, Rights, Roux-En-Y, Science, Science Citation Index, Science Citation Index Expanded, Software, Surgery, Symptoms, Systematic Review

? Cai, Y.L., Xiong, X.Z., Wu, S.J., Cheng, Y., Lu, J., Zhang, J., Lin, Y.X. and Cheng, N.S. (2013), Single-incision laparoscopic appendectomy vs conventional laparoscopic appendectomy: Systematic review and meta-analysis. World Journal of Gastroenterology, 19 (31), 5165-5173.

Full Text: 2013\Wor J Gas19, 5165.pdf

Abstract: AIM: To assess the differences in clinical benefits and disadvantages of single-incision laparoscopic appendectomy (SILA) and conventional laparoscopic appendectomy (CLA). METHODS: the Cochrane Library, MEDLINE, Embase, Science Citation Index Expanded, and Chinese Biomedical Literature Database were electronically searched up through January 2013 to identify randomized controlled trails (RCTs) comparing SILA with CLA. Data was extracted from eligible studies to evaluate the pooled outcome effects for the total of 1068 patients. The meta-analysis was performed using Review Manager 5.2.0. For dichotomous data and continuous data, the risk ratio (RR) and the mean difference (MD) were calculated, respectively, with 95%CI for both. For continuous outcomes with different measurement scales in different RCTs, the standardized mean difference (SMD) was calculated with 95%CI. Sensitivity and subgroup analyses were performed when necessary. RESULTS: Six RCTs were identified that compared SILA (n = 535) with CLA (n = 533). Five RCTs had a high risk of bias and one RCT had a low risk of bias. SILA was associated with longer operative time (MD = 5.68, 95%CI: 3.91-7.46, P < 0.00001), higher conversion rate (RR = 5.14, 95%CI: 1.25-21.10, P = 0.03) and better cosmetic satisfaction score (MD = 0.52, 95%CI: 0.30-0.73, P < 0.00001) compared with CLA. No significant differences were found for total complications (RR = 1.15, 95%CI: 0.76-1.75, P = 0.51), drain insertion (RR = 0.72, 95%CI: 0.41-1.25, P = 0.24), or length of hospital stay (SMD = 0.04, 95%CI: -0.08-0.16, P = 0.57). Because there was not enough data among the analyzed RCTs, postoperative pain was not calculated. CONCLUSION: the benefit of SILA is cosmetic satisfaction, while the disadvantages of SILA are longer operative time and higher conversion rate. (C) 2013 Baishideng. All rights reserved.

Keywords: Access, Acute Appendicitis, Analyses, Appendectomy, Benefits, Bias, Children, China, Chinese, Citation, Clinical, Co, Complications, Conventional, Conversion, Data, Database, Early Experience, Effects, Hong-Kong, Hospital, Hospital Stay, Laparoscopic, Length, Literature, Low Risk, Measurement, MEDLINE, Meta Analysis, Meta-Analysis, Metaanalysis, Methods, No, Operative, Outcome, Outcomes, P, Pain, Patients, People, Postoperative, Postoperative Pain, Prospective-Randomized-Trial, R, Randomized, RCT, Review, Rights, Risk, Room, Satisfaction, Scales, Science, Science Citation Index, Science Citation Index Expanded, Single Incision, Surgery, Systematic Review, World

? Chen, K., Xu, X.W., Zhang, R.C., Pan, Y., Wu, D. and Mou, Y.P. (2013), Systematic review and meta-analysis of laparoscopy-assisted and open total gastrectomy for gastric cancer. World Journal of Gastroenterology, 19 (32), 5365-5376.

Full Text: 2013\Wor J Gas19, 5365.pdf

Abstract: AIM: To evaluate the safety and efficacy of laparoscopy- assisted total gastrectomy (LATG) and open total gastrectomy (OTG) for gastric cancer. METHODS: A comprehensive search of PubMed, Cochrane Library, Web of Science and BIOSIS Previews was performed to identify studies that compared LATG and OTG. The following factors were checked: operating time, blood loss, harvested lymph nodes, flatus time, hospital stay, mortality and morbidity. Data synthesis and statistical analysis were carried out using RevMan 5.1 software. RESULTS: Nine studies with 1221 participants were included (436 LATG and 785 OTG). Compared to OTG, LATG involved a longer operating time [weighted mean difference (WMD) = 57.68 min, 95%CI: 30.48-84.88; P < 0.001]; less blood loss [standard mean difference (SMD) = -1.71; 95% CI: - 2.48 - - 0.49; P < 0.001]; earlier time to flatus (WMD= -0.76 d; 95% CI: - 1.22 - 0.30; P < 0.001); shorter hospital stay (WMD = -2.67 d; 95% CI: -3.96 - -1.38, P < 0.001); and a decrease in medical complications (RR = 0.41, 95% CI: 0.19-0.90, P = 0.03). The number of harvested lymph nodes, mortality, surgical complications, cancer recurrence rate and long-term survival rate of patients undergoing LATG were similar to those in patients undergoing OTG. CONCLUSION: Despite a longer operation, LATG can be performed safely in experienced surgical centers with a shorter hospital stay and fewer complications than open surgery. (C) 2013 Baishideng. All rights reserved.

Keywords: Analysis, Anastomosis, Blood, Blood Loss, Cancer, Complications, Efficacy, Flatus, Gastric Cancer, Gastroduodenostomy, Hospital, Hospital Stay, Laparoscopy, Long Term, Long-Term, Lymph-Node Dissection, Medical, Meta Analysis, Meta-Analysis, Metaanalysis, Methods, Morbidity, Mortality, Multicenter, Open, Open Distal Gastrectomy, Operation, P, Patients, Pubmed, Recurrence, Review, Rights, Safety, Science, Software, Statistical Analysis, Surgery, Surgical Complications, Surgical Outcomes, Survival, Survival Rate, Synthesis, Systematic Review, Term Outcomes, Total Gastrectomy, Trial, Web of Science

? Zhao, X.D., Cai, B.B., Cao, R.S. and Shi, R.H. (2013), Palliative treatment for incurable malignant colorectal obstructions: A meta-analysis. World Journal of Gastroenterology,