Richard paschal cochran, M. D. Personal data



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ABSTRACTS





  1. Cochran RP, Douglas DS. Renal function during cardiopulmonary bypass is not affected by low dose dopamine administration; Texas Medical Association, May 1989.

  2. Barth MJ, Cochran RP. Conservative utilization of subxyphoid exploration in penetrating thoracic trauma. Western Thoracic Surgical Association; June 1989, Monterey, Calif.

  3. Ring WS, Cochran RP, Nikaidoh H, Johnson NA, Braunlin EA, Fixler DE. Mechanical circulatory support following orthotopic heart transplantation in infants. J Heart & Lung Trans. 1991;(Suppl), January/February.

  4. Gulden RH , Whitten CW, Latson T, Lipton JM, Cochran RP, Elmore JC. Radiant heat reduces requirement for vasodilator drugs after cardiopulmonary bypass. Anesth Analg. 1991;72:S95.

  5. Cochran RP, Horton JW, Landreneau RJ, Verrier ED. Myocardial blood flow alterations in response to intra-aortic balloon counterpulsation in a canine hemorrhagic shock model. American College of Surgeons Surgical Forum Proceedings.

  6. Grande KJ, Kunzelman KS, Cochran RP, David TE, Verrier ED. Porcine aortic valve leaflet dimensions. ASAIO Abstracts, May 1992;33.

  7. Vocelka C, Cochran RP, Kunzelman KS, Verrier ED. Extracorporeal circuit for evaluation of lung preservation techniques. ASAIO abstracts, May 1992;61.

  8. Kunzelman KS, Cochran RP, Chuong CJ, Ring WS, Verrier ED, Eberhart RC. Finite element modeling of the mitral valve. Proceedings: Biomedical Engineering Society National Meeting, October 1992;G4.6.

  9. Kunzelman KS, Grande KJ, Cochran RP, David TE, Verrier ED. MRI analysis of the aortic valve. ASAIO Abstracts, May 1993;28.

  10. Grande KJ, Kunzelman KS, Cochran RP, David TE, Verrier ED. Comparative anatomy of the aortic valve and root: finite element model development. ASAIO abstracts, May 1993;28.

  11. Kunzelman KS, Cochran RP, Chuong CJ, Ring WS, Verrier ED, Eberhart RC. Mitral valve function: A finite element study. American College of Surgeons, Washington State Chapter Annual Meeting, June 1993.

  12. Cochran RP, Eddy AC, Hofer BO, Kunzelman KS, Verrier ED. The aortic valve sparing operation (David procedure) for aortic incompetence and ascending aneurysm of the aorta. The University of Washington Experience. American College of Surgeons, Committee on Medical Motion Pictures, October 1993.

  13. Grande KJ, Kunzelman KS, Cochran RP, Nelson JA, David TE, Verrier ED. Finite element model of the aortic valve and root. biomedical engineering society. Proceedings, 1993;22.

  14. Kunzelman KS, Cochran RP, Verrier ED. Replacement of mitral valve chordae tendineae with polytetrafluoroethylene suture–A finite element analysis. Society of Thoracic Surgeons, February 1994.

  15. Burdge EC, Kunzelman KS, Schmidt R, Verrier ED, Cochran RP. Digital analysis of mitral valve microstructure. American Society for Artificial Internal Organs, April 1994.

  16. Vocelka C, Spiess B, Soltow L, Thomas R, Gohra H, Akimoto H, Rothnie C, Kunzelman KS, Verrier ED, Cochran RP. Effects of a perfluorocarbon emulsion prime additive on EEG at the initiation of cardiopulmonary bypass in swine. American Society of Extracorporeal Technology, April 1994.

  17. Kunzelman KS, Burdge EC, Schmidt R, Verrier ED, Cochran RP. Digital analysis of mitral valve microstructure. International Symposium Cardiac Bioprostheses proceedings, p. 208.

  18. Cochran RP, Eddy AC, Hofer BO, Kunzelman KS, Verrier ED. Modified conduit preparation creates a pseudo-sinus in aortic valve sparing procedure for ascending aortic aneurysm. Western Thoracic Surgical Association proceedings, p. 56.

  19. Cochran RP, Kunzelman KS, Vocelka CR, Akimoto H, Gohra H, Soltow L, Spiess BD: Perfluorocarbon is protective as a prime, but not as a treatment for massive air embolus during cardiopulmonary bypass. The Brain and Cardiac Surgery proceedings, September 1994.

  20. Spiess BD, Cochran RP, Kunzelman KS, Vocelka CR, Soltow L, Thomas B, Akimoto H, Gohra H, Rothnie CL. Cerebral protection from massive air embolism with a perfluoro-carbon emulsion prime addition for cardiopulmonary bypass. Anesthesiology. 1994;81: A566.

  21. Cochran RP, Wright IH, Kunzelman KS, Anton WR, Verrier ED. Alterations in anesthesia and analgesia significantly reduces ventilator times in post-operative heart patients. Pacific Coast Surgical Association, Seattle, Wash, February 1995.

  22. Rand RP, Cochran RP, Aziz SA, Hofer BO, Allen MA, Verrier ED. Prospective trial of catheter irrigation and muscle flaps for sternal wound infections. Pacific Coast Surgical Association, Seattle, Wash, February 1995.

  23. Spiess BD, Soltow LO, Wright IH, Gillies BS, Cochran RP, Aziz S, Hofer BO, Verrier ED. Thromboelastography reflects the hypocoagulable status of acadesine. Society of Cardiovascular Anesthesiologists Annual Meeting, Philadelphia, Pa, May 1995.

  24. Stephens K, Lupinetti M, Cochran RP, Hofer B, Aziz S, Verrier E. The Ross procedure: emerging therapeutic option for aortic valve disease. Seattle Surgical Society Annual Scientific Program, Seattle, Wash, January 1996.

  25. Quick DW, Kunzelman KS, Kneebone J, Cochran RP. Collagen synthesis is upregulated in sheep mitral valves subject to altered stress. ASAIO J. 1996;42:29.

  26. Reimink MS, Kunzelman KS, Cochran RP. The effect of replacement suture length on the function and stresses of repaired mitral valves: A finite element study. ASAIO J. 1996;42:29.

  27. Kunzelman KS, Reimink MS, Cochran RP. Annular dilatation increases stress in the mitral valve and delays coaptation: A finite element computer model. European Society of Cardiovascular Surgeons, September 1996, Venice, Italy.

  28. Cochran RP, Kunzelman KS, Zwink T, Linker DT. Hemodynamic performance of standard St. Jude vs. St. Jude HP aortic prostheses. American Heart Association, November 1996.

  29. Rosoff JD, Soltow LO, Vocelka CR, Schmer G, Chandler WL, Cochran RP, Kunzelman KS, Spiess BD. second generation perfluorocarbon (perfluorodichlorooctane) does not increase complement activation in ex vivo extracorporeal bypass experiments. Society of Cardiovascular Anesthesiologists, 1996.

  30. Kunzelman KS, Reimink MS, Cochran RP. Rigid ring annuloplasty restores near normal stresses and coaptation in the mitral valve: A finite element model. American College of Cardiology, March 1997.

  31. Kunzelman KS, Cochran RP. Hemi-homograft replacement of the mitral valve: A finite element model. Stentless Bioprosthetics Meeting, April 1997, Noordwijk, The Netherlands.

  32. Cochran RP, Kunzelman KS. Effect of papillary muscle position on mitral valve stresses and function: Relationship to mitral homografts. VII International Symposium–Cardiac Bioprostheses, June 1997, Barcelona, Spain.

  33. Quick DW, Kunzelman KS, Eyre DR, Cochran RP. Regional collagen content of mitral valve leaflets: Impact on prosthetic design and impact of altered thickness or tissue stiffness on mitral valve stresses and coaptation. VII International Symposium–Cardiac Bioprostheses, June 1997, Barcelona, Spain.

  34. Grande KJ, Cochran RP, Reinhall P, Kunzelman KS. Regional variations in aortic root and valve stresses in a finite element model. International Society for Artificial Organs, Annual Meeting, Providence, RI, July 1997.

  35. Grande KJ, Cochran RP, Reinhall P, Kunzelman KS. Dacron root replacement alters aortic valve stresses: Finite element modeling. Cardiovascular Medicine, Surgery; Science, and Mechanics, June 1997, Washington, DC.

  36. Berman A, Cochran RP, Johansen K, Elger DF, Blacketter DF, Kunzelman KS. Thoracic aortic aneurysms have increased rupture risk vs. abdominal aortic aneurysms: A finite element analysis. Biomedical Engineering Society, October 1997, San Diego, Calif.

  37. Grande KJ, Cochran RP, Reinhall P, Kunzelman KS. Altered valve stresses in Osteogenesis imperfecta. Biomedical Engineering Society, October 1997, San Diego, Calif.

  38. Quick DW, Kunzelman KS, Cochran RP. Regional collagen content of mitral valve posterior leaflets: Impact on prosthetic valve design. Parker H Petit Institute for Bioengineering, Georgia Institute of Technology, Prosthetic Heart Valves: Future Technologies, Hilton Head, SC, February 1998.

  39. Grande KJ, Cochran RP, Kunzelman KS. Variations in aortic root sinus dimensions: Implications for stentless bioprostheses. Parker H Petit Institute for Bioengineering, Georgia Institute of Technology, Prosthetic Heart Valves: Future Technologies, Hilton Head, SC, February 1998.

  40. Kunzelman KS, Cochran RP. Pericardial patch repair of mitral valve leaflet perforation: Clinical case and finite element computer model. Third World Congress of Biomechanics Sapporo, Japan, August 1998.

  41. Carter YM, Allen, MD, Cochran RP. The renaissance of the human mitral valve homograft. 8th Annual Scientific Symposium of the Society of Black Academic Surgeons, Washington, DC, April 17, 1998.

  42. Grande KJ, Cochran RP, Reinhall PG, Kunzelman KS. Influence of aging on aortic root and valve function. ASAIO J. 1998;44:17.

  43. Cochran RP, Austin R, Kunzelman KS, Curtis W, Verrier ED. Repair of ascending aortic transection. American College of Surgeons. Committee on Motion Pictures, Orlando, Fla, October 1998.

  44. Lee AS, Lawrence O, Scatena M, Giachelli C, Cochran RP, Kunzelman KS. Extracellular matrix proteins enhance the adhesion and ND-B activation of endothelial cells subject to shear stress. American College of Surgeons, Orlando, Fla, October 1998.

  45. Quick DW, Kunzelman KS, Cochran RP. Quantitative histologic analysis of the mitral valve. Annual Meeting of the International Society for Optical Engineering. Presented, January 1998.

  46. Love RB, Cornwell RD, Welter DL, Canver CC, Cochran RP, Meyer KC. Extended human lung preservation with UW solution. American Lung Association/American Thoracic Society International Conference, San Diego, Calif, accepted, April 23-28, 1999.

  47. Einstein D, Kunzelman KS, Thomas R, Rothnie C, Cochran RP. Non-invasive deter-mination of mitral valve acoustic properties: A proposed method to determine tissue alterations due to disease. World Congress on Heart Valve Disease, January 1999.

  48. Kunzelman KS, Tapia M, Cochran RP. Computer modeling for evaluation of surgical intervention for cardiac valvular disease. World Congress on Heart Valve Disease, January 1999.

  49. Kunzelman KS, Linker DT, Sai S, Miyake-Hull C, Quick D, Thomas R, Rothnie C, Cochran RP. A sheep model for acute mitral regurgitation using echocardiographic guidance. World Congress on Heart Valve Disease, January 1999.

  50. Cochran RP, Raikar G, Kunzelman KS. Right atrial myxoma arising from the coronary sinus and presenting emergently. American College of Surgeons. October 2000.

  51. Einstein D, Kunzelman KS, Reinhall PG, Cochran RP. Dynamic finite element implementation of a nonlinear, anisotropic, pseudo-elastic formulation for cardiac valve tissue. World Congress on Medical Physics and Biomedical Engineering, Chicago, July 2000.

  52. Kunzelman KS, Cochran RP. Computer modeling for evaluation of cardiac valvular function. World Congress on Medical Physics and Biomedical Engineering, Chicago, July 2000.

  53. Cochran RP, Kunzelman KS. Biomechanics in cardiac surgery: Evolution from “macro” to “micro”. World Congress on Medical Physics and Biomedical Engineering, Chicago, July 2000.

  54. Quick DW, Kunzelman KS, Cochran RP. Biomechanics of surgery: Analysis of physical loads and fatigue potential. World Congress on Medical Physics and Biomedical Engineering, Chicago, July 2000.

  55. Dwyer K, Kunzelman K, Quick D, Jensen K, Cochran R. Age dependent procollagen expression in human mitral valves. World Society Cardiothoracic Surgeons Congress, Vancouver, BC, August 2000.

  56. Jensen K, Kunzelman K, Quick D, Dwyer K, Cochran R. Regurgitation dependent cellular nuclei presence in human mitral valves. World Society Cardiothoracic Surgeons Congress, Vancouver, BC, August 2000.

  57. Quick D, Kunzelman K, Rahko P, Hata M, Jensen K, Dwyer K, Hegge J, Cochran R. Regurgitation dependent heat shock expression in Ovine Mitral Valves. World Society Cardiothoracic Surgeons Congress, Vancouver, BC, August 2000.

  58. Cochran R, Love R, Woolley D, Sollinger H, Kunzelman KS. Success of combined heart/kidney transplantation. 2nd International Meeting of the Onassis Cardiac Surgery Center, Athens, Greece, December 2000.

  59. Quick D, Kunzelman K, Hata M, Hegge J, Rahko P, Cochran R. Effect of ACE Inhibitors on Mitral Valve Heat Shock Protein and Procollagen Expression following Myocardial Infarction. 2nd International Meeting of the Onassis Cardiac Surgery Center, Athens, Greece, December 2000.

  60. Kasalko J, Kunzelman K, Nicosia M, Einstein D, Cochran R. Biaxial material properties of the porcine aortic wall. Society for Heart Valve Disease Annual Meeting, London, England, June 2001.

  61. Nicosia M, Cochran R, Reinhall P, Einstein D, Kunzelman K. Coupled fluid-structure model of the aortic valve and root. Society for Heart Valve Disease Annual Meeting, London, England, June 2001.

  62. Nicosia M, Cochran RP, Kunzelman KS. A coupled fluid-structure finite element model of the aortic valve and root. Prosthetic Heart Valve Workshop, Hilton Head, SC, March, 2002.

  63. Einstein D, Kunzelman K, Reinhall P, Nicosia M, Cochran RP. Finite element implementation of a structural constitutive equation for aortic valve tissue. Society for Industrial and Applied Mathematics, Boston, MA, March 2002.

  64. Einstein DR, Reinhall P, Nicosia MA, Kunzelman KS, Cochran RP. Finite element implementation of a structural model for aortic valve tissue. World Congress Biomechanics, Calgary, Canada, July 2002.

  65. Jensen KT, Kunzelman KS, Dwyer KW, Quick DW, Cochran RP. Regional differences in cellular densities in human and ovine mitral valves. World Congress Biomechanics, Calgary, Canada, July 2002.

  66. Nicosia MA, Cochran RP, Kunzelman KS. Coupled fluid-structure finite element modeling of the aortic valve and root. Biomedical Engineering Society Annual Meeting, Houston, TX, October 2002.

  67. Weigel T, Quick D, Kunzelman K, Johnson C, Cochran R. Robotic lung resection with Zeus in a pig model. Society of American Gastrointestinal Endoscopic Surgeons Annual Meeting, Los Angeles, CA, March, 2003.

  68. Kunzelman KS, Quick DW, Weigel TL, Klos SS, Cochran RP. Effects of surgeon experience on the surgical robotics learning curve. Society of American Gastrointestinal Endoscopic Surgeons Annual Meeting, Los Angeles, CA, March, 2003.

  69. Nicosia MA, Cochran RP, Einstein DR, Kunzelman KS. Coupled fluid-structure finite element modeling of the aortic root and valve. Maine Biological and Medical Sciences Symposium, Bar Harbor, Maine, April 2003.

  70. Einstein DR, Kunzelman KS, Reinhall PG, Nicosia MA, Cochran RP. Nonlinear fluid-coupled computational model of the mitral valve. Society for Heart Valve Disease, Paris, France, July 2003.

  71. **Einstein DE, Kunzelman KS, Reinhall PG, Nicosia MA, Cochran RP. Functional and dysfunctional proliferation in the mitral Valve: A computational study of the relationship of tissue integrity to MR and S1. World Congress on Medical Physics and Biomedical Engineering, Sydney, Australia, April 2003.

  72. Brown JR, Cochran RP, Dacey LJ, Ross CS, Kunzelman KS, Dunton RF, Braxton JH, Charlesworth DC, Clough RA, Helm RE, Leavitt BJ, MacKenzie TA, O’Connor. Perioperative increases in serum creatinine are predicitive of increased 90-day mortality following cardiac surgery. American Heart Association Annual Meeting, Dallas, Texas, November 2005.

  73. Baribeau YR, Leavitt BJ, Braxton H, Nugent WC, Cochran RP, Hernandez FH, Helm RE, Dunton RF, Olmstead EM, O’Connor GT, Malenka DJ. Long-term survival following coronary artery bypass graft surgery is related to completeness of revascularization. American Heart Association Annual Meeting, Dallas, Texas, November 2005.

  74. Brown JR, Cochran RP, Leavitt BJ, Ross CS, MacKenzie TA, Kunzelman KS, Kramer RS, Hernandex F, Helm RE, Westbrook BM, Dunton RF, O’Connor GT Decision Support for Coronary Revascularization, American College of Cardiology Annual Meeting, presented, March 2006.




  1. Brown JR, Cochran RP, Leavitt BJ, Ross CS, MacKenzie TA, Kunzelman KS, Kramer RS, Hernandex F, Helm RE, Westbrook BM, Dunton RF, O’Connor GT. Multivariate prediction of renal insufficiency developing after cardiac surgery. American Heart Association, presented, Nov 2006.




  1. Brown JR, Cochran RP, Dacey LJ, Ross CS, Kunzelman KS, Dunton RF, Braxton JH, Charlesworth DC, Clough RA, Helm RE, Leavitt BJ, MacKenzie TA, O’Connor GT. Glomerular filtration rate after cardiac surgery is predictive of 90-day mortality. American Association of Thoracic Surgery, presented, May 2006.




  1. Schievano S, Nicosia M, Cochran RP, Khambadkone S, Einstein DR, Bohfoeffer P, Kunzelman KS. Percutaneous Mitral Valve Dilatation: Single Balloon Versus Double Balloon – A Finite Element Analysis, Society for Heart Valve Disease, New York, NY presented June 2007.





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