Sustaining hiv vaccine Communications and Outreach


NHVREI Key Message Platform



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NHVREI Key Message Platform



No major viral epidemic has been defeated without a vaccine.

  1. It is important that community efforts support HIV vaccine research.

  2. HIV prevention, treatment, and vaccine research are all essential for understanding and fighting the HIV/AIDS epidemic.

2. The best long-term hope for controlling the AIDS epidemic is the development of safe, effective, and affordable preventive HIV vaccines.

  1. Every year, an estimated 56,000 people become infected with HIV in the United States.

  2. Every 9 ½ minutes, someone in the U.S. is infected with HIV.

  3. An HIV vaccine is critical for the communities most impacted by HIV in America.

  4. Historically, vaccines have been the most powerful weapon against infectious diseases like polio, measles, and Hepatitis B.

3. Currently, there is no HIV vaccine.


  1. There are many challenges to developing an HIV vaccine, but, each new study teaches us more about how the body can fight the virus, making it possible to develop better HIV vaccine candidates.

  2. HIV vaccine research requires a two-pronged approach: basic research to help us learn more about HIV, as well as development and testing of potential HIV vaccines. Clinical research is needed for both of these, and many clinical studies contribute simultaneously to both goals.

  3. In 2009, a vaccine tested in Thailand prevented HIV infection in some study participants. This gives us hope that we can one day find a vaccine that works well for everyone.

  4. Dozens of different vaccine candidates and approaches are at various stages of scientific development.

  5. To know if an HIV vaccine will work across a variety of people, clinical trials need participation from a diverse population of volunteers, including those from groups most at risk for HIV infection.

4. HIV vaccines do not infect study participants with HIV.


  1. HIV vaccine candidates do not contain the HIV virus.

  2. In the past twenty years, tens of thousands of volunteers have safely participated in HIV vaccine research trials.

  3. Community support is essential to break down stigma and myths about HIV vaccine research.

  4. Involvement from community leaders across the United States is vital to help educate and inform community members about HIV vaccine research.


5. The safety of trial volunteers is always the top priority in HIV vaccine research.

  1. Every study seeks to protect the safety of its volunteers.

  2. Institutional review boards are independent groups whose aim is to protect the safety and well being of trial volunteers. They do this by carefully reviewing the details of trials from start to end; in addition, the U.S. Food and Drug Administration, which regulates all U.S. Government-sponsored trials, carefully reviews all trials for potential safety issues.

  3. Clinical trials may involve unknown risks.


6. Be the generation to find a vaccine to prevent HIV.


  1. Learn the facts at www.bethegeneration.nih.gov

  2. Talk to friends and family about the need for an HIV vaccine. Let them know you are supportive of HIV vaccine research.

  3. Join a community advisory board or other education efforts in your area.

  1. Encourage vaccine research participants and/or become one yourself. HIV vaccine research requires partnership between governments, businesses, universities, international agencies, national and local organizations, advocates, and communities.

Credible Sources in HIV Prevention Research:


Useful Links to Groups that Work in HIV Prevention
AIDS.gov
http://aids.gov/
Through the use of innovative, new media strategies, AIDS.gov seeks to increase HIV testing among at-risk populations and improve care for those living with HIV. The AIDS.gov web portal offers access to Federal HIV information, policies, programs and resources in order to raise awareness of the disease.

AIDSinfo


http://www.aidsinfo.nih.gov/
AIDSinfo is a U.S. Department of Health and Human Services (HHS) project that offers the latest federally approved information on HIV/AIDS clinical research, treatment and prevention, and medical practice guidelines for people living with HIV/AIDS, their families and friends, health care providers, and researchers. AIDSinfo serves as the main dissemination point for federally approved HIV treatment and prevention guidelines, and provides information on clinical research trials for HIV infected patients. All of the information provided by AIDSinfo is from federal government agencies, including the National Institutes of Health, Centers for Disease Control and Prevention, Health Resources and Services Administration among others.

AVRS – The AIDS Vaccine Research Subcommittee (National Institute of Allergy and Infectious Diseases)
http://www.niaid.nih.gov/topics/hivaids/research/vaccines/advisory/avrs/Pages/default.aspx
A subcommittee of the NIAID AIDS Research Advisory Committee (ARAC), AVRS aids in the formation of a comprehensive research program in order to accelerate the development of an HIV/AIDS vaccine. Members of the group advise NIH research programs on knowledge gaps, scientific opportunities and future courses of research.

DAIDS – The Division of Acquired Immune Deficiency Syndrome


www3.niaid.nih.gov/about/organization/daids
DAIDS is a Division within the National Institute of Allergy and Infectious Diseases (NIAID), a component of the National Institutes of Health (NIH) in Bethesda, MD. DAIDS was formed in 1986 to develop and implement the national research agenda to address the HIV/AIDS epidemic. Specifically, the mission of DAIDS is to help ensure an end to the HIV/AIDS epidemic by increasing basic knowledge of the pathogenesis and transmission of the human immunodeficiency virus (HIV), supporting the development of therapies for HIV infection and its complications and co-infections, and supporting the development of vaccines and other prevention strategies. While the following link is not specific to HIV vaccine research, information about the NIAID’s research program can be found at http://www.niaid.nih.gov/topics/hivaids/Pages/Default.aspx

DHAP – The Division of HIV/AIDS Prevention (Centers for Disease Control and Prevention, CDC)
http://www.cdc.gov/hiv/
DHAP, a division of the CDC’s Coordinating Center for Infectious Diseases, works to prevent HIV infection and reduce HIV-related illness and death. By providing national leadership and support for HIV prevention research, HIV prevention programs and effective biomedical interventions to reduce HIV transmission and progression.

USAID – United States Agency for International Development


http://www.usaid.gov/our_work/global_health/aids/TechAreas/research/vaccinefactsheet.html
USAID provides support to the International AIDS Vaccine Initiative (IAVI), a non-governmental organization, to accelerate the development of an effective vaccine for HIV prevention. USAID funds are used to support Vaccine Development Partnerships that are focused on advancing HIV vaccine candidates to clinical trials. Among the activities supported within a five-year Cooperative Agreement are site development and community preparations for HIV vaccine efficacy trials in developing countries and public policy research to accelerate and support HIV vaccine research/development and future access. Vaccine clinical trial centers have been established in Kenya, Uganda, Rwanda, Zambia, South Africa, and India.

USMHRP - U.S. Military HIV Research Program


http://www.hivresearch.org/
USMHRP is a tri-service research effort striving to develop a globally effective and safe HIV vaccine to protect at-risk military and civilian populations and to improve public health worldwide. The Program is headed by the Walter Reed Army Institute of Research in collaboration with the Henry M. Jackson Foundation for the Advancement of Military Medicine. USMHRP is dedicated to HIV vaccine development, prevention, disease surveillance, and care and treatment for HIV.

VRC – The Dale and Betty Bumpers Vaccine Research Center


www.niaid.nih.gov/vrc/clintrials/clinstudies.htm
The VRC, a component of the National Institutes of Allergy and Infectious Diseases (NIAID),conducts preventive HIV vaccine research and development at a facility located on the campus of the National Institutes of Health (NIH) in Bethesda, MD.

HVTN – The HIV Vaccine Trials Network


http://www.hvtn.org/
The HVTN is an international organization of scientists and researchers who have come together to develop a safe and effective preventive HIV vaccine. It facilitates the production and testing of vaccines against HIV/AIDS and conducts all phases of clinical evaluation, from testing experimental vaccines for safety to testing the effectiveness of vaccines in preventing HIV. First established in 1999, the HVTN is funded by the Division of AIDS (DAIDS) of the National Institute of Allergy and Infectious Diseases (NIAID).

Hope Takes Action
www.hopetakesaction.org
Hope Takes Action is a social marketing campaign associated with HVTN 505, an HIV vaccine trial managed by the HIV Vaccine Trials Network (HVTN).

HPTN – HIV Prevention Trials Network
http://www.hptn.org/index.htm
HPTN is a global clinical trials network funded by the Division of AIDS (DAIDS) of the National Institute of Allergy and Infectious Diseases (NIAID). HPTN develops and tests the safety and efficacy of non-vaccine HIV prevention treatments like antiretrovirals.

The Legacy Project
www.vaccineforall.org
The Legacy Project works to encourage full participation of African Americans and Latinos in HIV vaccine development – from trial volunteers to scientists. The organization addresses the history of abuse of minorities in research trials and is working to build trust between the scientific community and people of color.

IAVI – International AIDS Vaccine Initiative


http://www.iavi.org/
IAVI is a global not-for-profit organization working to speed the search for a vaccine to prevent HIV infection and AIDS. Founded in 1996 and operational in 23 countries, IAVI and its network of partners research and develop vaccine candidates. IAVI also advocates for a vaccine to be a global priority and works to ensure that a future vaccine will be accessible to all who need it.

AVAC
http://www.avac.org/


A community-based organization, AVAC has been working for 10 years to accelerate the ethical development and global delivery of vaccines against HIV/AIDS. AVAC provides independent analysis of developments in HIV/AIDS prevention and treatment, public education on vaccine research, policy advocacy, and helps local communities support and stay informed about HIV vaccine and other HIV prevention clinical trials.

CAVD – The Collaboration for AIDS Vaccine Research
http://www.cavd.org/Pages/default.aspx
CAVD is an international group of experts and scientists that works to develop innovative and viable HIV vaccine candidates to progress to clinical trials. CAVD aims to advance HIV vaccine research by balancing individual creativity with information sharing and laboratory standardization.

Global HIV Vaccine Enterprise (The Enterprise)


http://www.hivvaccineenterprise.org/
The Enterprise is an international network of independent organizations working together toward the development of a safe and effective HIV vaccine. In 2010, the Enterprise released a Scientific Strategic Plan (the Plan) for HIV vaccine development.

UNAIDS – The Joint United National Programme on HIV/AIDS
http://www.unaids.org/en/
A United Nations (UN) partnership which works to unite the UN, national governments, the private sector, civil society, global institutions and people living with HIV in order to improve access to HIV prevention, treatment, care and support.

CHAVI – Center for HIV/AIDS Vaccine Immunology
https://chavi.org/
CHAVI is virtual center consisting of a consortium of universities and academic medical institutions and is funded by the National Institute of Allergy and Infectious Diseases (NIAID). It was established in 2005 and seeks to overcome challenges in HIV vaccine design and improve HIV vaccine development.

GCM – Global Campaign for Microbicides
http://www.global-campaign.org/
GCM promotes ethical and speedy development of and access to HIV prevention – particularly for women – through collaboration with civil society, researchers, policymakers and industry. GCM works to share resources, inform and develop policy, identify and promote better practices, and build and strengthen the capacity of HIV-prevention.



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