Having genetic problem is uncontrollable. It is not some kind of consequence of our unhealthy lifestyle or maybe sometimes it can but there were people that were healthy but still able to produce unwanted gene to their children like for example the down’s syndrome. With this, deepening our understanding of the etiologies of this malformation syndrome is important. And also not only for the genetic matter but as well as those who were struggling having this malformation. It is not like they wanted to be born like that and we should widen our help for this kind people. And also I think it is nice to give other people ideas why there are children who were in this kind of syndrome because I have encountered people thinking that it is the mother’s fault why did their children became like that.