Wongpakaran et al.14 2007
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SSRI use associated with apathy among depressed elderly
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Case-control of 384 depressed elderly divided into SSRI and non-SSRI groups studied with GDS-apathy and HAMD-apathy subscale at discharge- apathy greater in SSRI group
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384 elderly depressed patients from geriatric day care database receiving antidepressants.
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Retrospective records from database that identified 2 groups of patients with SSRI use versus non-SSRI.
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SSRI group predictor for apathy as measured by Geriatric Depression and Hamilton Rating apathy subscales OR 1.9 (1.14 – 3.17)
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