A critical Review of the literature on the effects of emotional blunting and apathy associated with selective serotonin reuptake inhibitors
RANZCP SCHOLARLY PROJECT
WORD COUNT: 3,298
Introduction 3
Aims 3
Background 3
Definitions 5
Method 5
Data Sources and Search Terms 5
Study Inclusion Criteria and Selection 7
Exclusion Criteria 7
PRISMA Flow Diagram 7
Results 8
Quality of the evidenceOverview 17
Discussion 23
The RCTs are of poor quality and no conclusions can be drawn. However, they present some interest in their various methodologies in measuring emotional blunting or apathy. 23
Implications and Limitations 27
Conclusions 27
Conflict of Interests 27
Acknowledgements 27
References 28
Aims
To systematically identify and appraise the literature to study the prevalence of the cluster of emotional and behavioral effects known as emotional blunting and apathy respectively, in patients being treated with Selective Serotonin Reuptake Inhibitors (“SSRI”).
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