Black Cohosh Hailey Taylor What is this supplement taken for?
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Management of menopausal symptoms
Premenstrual discomfort
Dysmenorrhea
Rheumatism
Dosage
Tablets (Remifemin)– 20 mg twice daily
Liquid extract– 0.3–2 mL 2–3 times daily.
Tincture– 2–4 mL 2–3 times daily.
Dried rhizome– 0.3–2 g 3 times daily.
Pathophysiology
“Therapeutic effects are produced by glycosides isolated from the fresh or dried rhizome with attached roots”
However, the mechanism of action is unknown.
Effectiveness
Efficacy of black cohosh in treating early symptoms of menopause: a randomized clinical trial
This study aimed to evaluate the effectiveness in the supplement black cohosh in treating symptoms of menopause. The treatment group showed significantly more improvement than the control group with symptoms, and no side effects were reported.
Side Effects
Cramping
1
Headache
2
GI Upset
3
Rash
4
Weight Gain
5
Seizures
(in combination with evening primrose and chasteberry)
6
Interactions
May increase risk of hepatotoxicity when used with chaparral, comfrey, kava-kava, and niacin.
Alcohol-containing preparations may interact with disulfiram and metronidazole.
May decrease cytotoxic effects of cisplatin.
May precipitate hypotension when used in combination with antihypertensives.
References
Vallerand, A. H., Sansoki, C. A. (2021). Davis’s Drug Guide for Nurses (17th ed.). F.A. Davis Company.
Mohammad-Alizadeh-Charandabi, S. Shahnazi, M. Nahaee, J. Bayatipayan, S. (2013). Efficacy of black cohosh (Cimicifuga racemosa L.) in treating early symptoms of menopause: a randomized clinical trial. National Library of Medicine. https://doi.org/10.1186/1749-8546-8-20
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