diagnostic results are delayed, treatment should be started on the based on clinical indicators and travel history.
• If the patient has
taken malaria chemoprophylaxis, the same medicine should not be used for treatment.
• The possibility of mixed
P. falciparum–P. vivax infections must always be considered. Travellers who acquire malaria while still in the malaria-endemic country should be treated in accordance with the national policy of the country.
P. falciparum Chemoprophylaxis and treatment of falciparum malaria are
becoming more complex because P. falciparum is increasingly resistant to various antimalarial drugs. Chloroquine can no longer be used for prevention and treatment of falciparum malaria. The following combination therapies are suitable for treatment of uncomplicated
falciparum malaria in travellers on return to countries or areas of no risk
•
artemether–lumefantrine
•
dihydroartemisinin–piperaquine
•
atovaquone-proguanil. Note The artemisinin combination therapies are preferred because treatment failures are consistently lower than 5% in settings without resistance to the partner drug.
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