Title: Toxicology of Metals: Clinical and Experimental Research

Title: Toxicology of Metals: Clinical and Experimental Research

Brown, S.S. and Kodama, Y. (1987), Toxicology of Metals: Clinical and Experimental Research, Ellis Horwood Limited, New York, Chichester, Brisbane and Toronto.

Sunderman, Jr., F.W. (1987), Physicochemical and biological attributes of nickel compounds in relationship to carcinogenic activities. in Toxicology of Metals: Clinical and Experimental Research, (Edited by Brown, S.S. and Kodama, Y.), Ellis Horwood Limited, New York, Chichester, Brisbane and Toronto, 255-365.

Title: Toxicon

ISO Abbreviated Title: Toxicon

JCR Abbreviated Title: Toxicon

ISSN: 0041-0101

Issues/Year: 12

Journal Country/Territory: England

Language: Multi-Language

Publisher: Pergamon-Elsevier Science Ltd

Publisher Address: The Boulevard, Langford Lane, Kidlington, Oxford OX5 1GB, England

Subject Categories:

Pharmacology & Pharmacy: Impact Factor181 (2000)

Toxicology: Impact Factor

Notes: highly cited

? Gutierrez, J.M., Gene, J.A., Rojas, G. and Cerdas, L. (1985), Neutralization of proteolytic and hemorrhagic activities of Costa Rican snake-venoms by a polyvalent antivenom. Toxicon, 23 (6), 887-893.

Full Text: 1985\Toxicon23, 887.pdf

? Gene, J.A., Roy, A., Rojas, G., Gutierrez, J.M. and Cerdas, L. (1989), Comparative-study on coagulant, defibrinating, fibrinolytic and fibrinogenolytic activities of Costa-Rican crotaline snake-venoms and their neutralization by a polyvalent antivenom. Toxicon, 27 (8), 841-848.

Full Text: 1989\Toxicon27, 841.pdf

Morris, R.J., Williams, D.E., Luu, H.A., Holmes, C.F.B., Andersen, R.J. and Calvert, S.E. (2000), The adsorption of microcystin-LR by natural clay particles. Toxicon, 38 (2), 303-308.

Full Text: T\Toxicon38, 303.pdf

Abstract: The microcystin cyanobacterial hepatotoxins represent an increasingly severe global health hazard. Sines microcystins are found world wide in drinking water reservoirs concern about the impact on human health has prompted investigations into remedial water treatment methods. This preliminary study investigates the scavenging from water of microcystin-LR by fine-grained particles known to have a high concentration of the clay minerals kaolinite and montmorillonite. The results show that more than 81% of microcystin-LR can be removed from water by clay material. Thus, microcystin-LR is indeed scavenged from water bodies by fine-grained particles and that this property may offer an effective method of stripping these toxins from drinking water supplies. (C) 1999 Elsevier Science Ltd. All rights reserved.

Keywords: Protein Phosphatase Inhibitors, Diarrhetic Shellfish Toxins, Oscillatoria-Agardhii, Tumor Promotion, Okadaic Acid, Cyanobacteria, Identification, Bloom, Decomposition, Environment

? Guimaraes, J.A. and Carlini, C.R. (2004), Most cited papers in Toxicon. Toxicon, 44 (4), 345-359.

Full Text: 2004\Toxicon44, 345.pdf

Abstract: Citation of a published work is one of the parameters considered in the analysis of relevance and importance of scientific contributions. In 2002. for the first time the Impact Factor of Toxicon has risen above 2.0, placing it at the 17th position among 76 journals in the ‘toxicology’ field. The aim of this article was to identify the most cited articles in Toxicon, that have contributed to the steady increase of its Impact Factor. The number of citations, complete reference and type of all documents appearing in Toxicon in the period 1963-2003 were retrieved from the ISI Web-of-Science homepage. The documents retrieved were sorted by the number of citations received. A ‘citation index’, defined as the number of citations divided by the number of years since publication, was calculated for each document. It was clearly seen that reviews in Toxicon received 4.4-fold more citations than articles. Unexpectedly, it was found that recent papers were proportionally more cited than old ones. A decrease in the proportion of papers dealing on ‘snake*’ through out the period and the broadened range of subjects of the most cited papers recently published in Toxicon reflects an increased ‘visibility’ in other fields of toxinology. Research on plant toxins gained its own space in Toxicon with newer publications showing high citation indexes. It can be postulated that these facts helped to increase Toxicon’s Impact Factor from 1.248 in 1999 to 2.003 in 2002. With the increased number of issues in Toxicon as well as publications of subject-dedicated volumes containing mostly reviews, the Impact Factor of Toxicon is expected to keep rising in the near future. (C) 2004 Elsevier Ltd. All rights reserved.

Keywords: Anabaena-Flos-Aquae, Analysis, Blue-Green-Algae, Bothrops-Asper Venom, Buthus-Martensi Karsch, Citation, Citation Index, Citation Indexes, Citations, Cyanobacteria, Cyanobacterium Microcystis-Aeruginosa, Eclipta-Prostrata Asteraceae, Engaddensis Burrowing Asp, Impact, Impact Factor, Indexes, ISI, Isi Web of Science, Journals, Linked-Immunosorbent-Assay, Papers, Paralytic Shellfish Toxins, Plant, Plant Lantana-Camara, Plant Toxins, Publication, Publications, Research, Snakes, Visibility, Web of Science

? Qiao, R.P., Li, N., Qi, X.H., Wang, Q.S. and Zhuang, Y.Y. (2000), Degradation of microcystin-RR by UV radiation in the presence of hydrogen peroxide. Toxicon, 45 (6), 745-752.

Full Text: T\Toxicon38, 745.pdf

Abstract: Experiments were conducted to investigate the degradation of microcystin-RR in order to assess the effectiveness and feasibility of the combined UV/H₂O₂ catalytic system for purification of water polluted by microcystins. The operating parameters such as hydrogen peroxide dosage, pH value, UV light intensity, initial concentration of microcystin-RR and reaction time were evaluated, respectively. The degradation efficiency increased nonlinearly with increasing UV light intensity and hydrogen peroxide dosage, respectively. There existed an optimal hydrogen peroxide dosage, beyond which the reagent exhibited an inhibitory effect, for degrading microcystin-RR. The degradation process could be fitted by both of the pseudo-first-order and second-order kinetics well and primarily followed a mechanism of both direct photolysis and hydroxyl radical oxidation. Compared with the treatment using UV radiation and hydrogen peroxide individually, the combined UV/H₂O₂ system could significantly enhance the degradation efficiency due to the synergetic effect between UV radiation and hydrogen peroxide oxidation. The observed rate constants decreased and the corresponding half-lives prolonged as the concentrations of microcystin-RR increased. The combined UV/H₂O₂ process provides an effective technology for the removal of microcystins from drinking water supplies. (c) 2005 Elsevier Ltd. All rights reserved.

Keywords: Photocatalytic Degradation, Microcystins, Combined UV/H₂O₂ Process, Kinetics, Water-Treatment Processes, Cyanobacterial Toxins, Ultraviolet-Radiation, Titanium-Dioxide, Photocatalytic Degradation, Treatment Options, Kinetic-Model, Destruction, Hepatotoxins, LR

? Chen, X.G., Xiao, B.D., Liu, J.T., Fang, T. and Xu, X.Q. (2000), Kinetics of the oxidation of MCRR by potassium permanganate. Toxicon, 45 (7), 911-917.

Full Text: T\Toxicon45, 911.pdf

Abstract: The occurrence of the microcystins in the water bodies, especially in drinking water resources, has received considerable attentions. In situ chemical oxidation is a promising cost-effective treatment method to remove MC from water body. This research investigated the reaction kinetics of the oxidation of MCRR by permanganate. Experimental results indicate that the reaction is second order overall and first order with respect to both permanganate and MCRR, and has an activation energy of 18.9 kJ/mol. The second-order rate constant ranges from 0.154 to 0.225 l/mg/min at temperature from 15 to 30°C. The MCRR degradation rates can be accelerated through increasing reaction temperature and oxidant concentration. The reaction under acid conditions was slightly faster than under alkaline conditions. The half-life of the reaction was less than 1 min, and more than 99.5% of MCRR was degraded within 10 min. (c) 2005 Elsevier Ltd. All rights reserved.

Keywords: Microcystin-RR, Potassium Permanganate, Oxidation, Kinetics, Water-Treatment, Microcystin-LR, Cyanobacterial Toxins, Removal, Hepatotoxin, Dioxide, Carbon, Acid