chimera, P
Y
MOI, NCBI’s Entrez, BLAST,
PSI-BLAST, clustal W, Pfam, PRINTS, BLOCKS,
Prosite and PDB.
BCH 412 ADVANCED BIOCHEMICAL METHODS (2 Units) Principles of instrumentation. Principles, methodologies and applications of electrophoresis. Chromatography –
paper chromatography, thin layer chromatography, column chromatography,
ion exchange, gel filtration. Spectroscopy and spectrophotometry (Infrared, visble and ultraviolet absorption, fluorescence, phosphorescence. Centrifugation and isotopic techniques. Optical methods.
BCH 414 FUNDAMENTALS OF BIOSIGNALLING AND ONCOLOGY (2 Units). Structure and function of signal pathways signaling of nuclear receptors. G-protein coupled
signal transmission pathway, Intracellular messengers/second messengers, serine/threonine specific protein kinases, tyrosine-specific
protein phosphatases, ras protein-protein kinase, MAP kinases, membrane receptors with associated tyrosine kinase activity (JANUS kinase, other receptor classes. Regulation of cell cycle. Malfunction of signaling pathways and tumorigenesis. Oncogenes and tumor suppressor genes. Apoptosis.
BCH 499 RESEARCH PROJECTS (6 Units) Independent research findings into selected areas/topics of interest to the academic staff. Students will be required to carryout literature
survey on the topics, perform experiments and produce reports (preferably at the end of second semester. Students will be subjected to both seminar and oral examination on the projects undertaken.
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