Accounting concepts
Download 441.32 Kb.
|
- Navigate this page:
- ASHUTOSh R. PANDYA
- Definitions
Conclusion: Prediction of Solubility and other related physiochemical properties at the early stage of drug discovery has become really important to reduce the chances of drug failure at the later stage. There are a lot of solubility data sources and packages available to facilitate the process; still the need of an hour is to develop naval and robust hands on software applications to make the process more efficient and thus increase the chances of design and develop the successful drug. References: [1] J. Wang and T. Hou, “Chapter 5 Recent Advances on in silico ADME Modeling,” Annu. Rep. Comput. Chem., vol. 5, pp. 101–127, 2009. [2] I. Kola and J. Landis, “Can the pharmaceutical industry reduce attrition rates?,” Nat. Rev. Drug Discov., vol. 3, no. 8, pp. 711–5, Aug. 2004. [3] T. Hou and J. Wang, “Structure-ADME relationship: still a long way to go?,” Expert Opin. Drug Metab. Toxicol., vol. 4, no. 6, pp. 759–70, Jun. 2008. [4] T. J. Hou, K. Xia, W. Zhang, and X. J. Xu, “ADME evaluation in drug discovery. 4. Prediction of aqueous solubility based on atom contribution approach.,” J. Chem. Inf. Comput. Sci., vol. 44, no. 1, pp. 266–75. [5] W. L. Jorgensen and E. M. Duffy, “Prediction of drug solubility from structure.,” Adv. Drug Deliv. Rev., vol. 54, no. 3, pp. 355–66, Mar. 2002. [6] “U S Food and Drug Administration Home Page.” [Online]. Available: http://www.fda.gov/. [Accessed: 17-Jul-2014]. [7] J. Wang and T. Hou, “Recent advances on aqueous solubility prediction.,” Comb. Chem. High Throughput Screen., vol. 14, no. 5, pp. 328–38, Jun. 2011. [8] R. Todeschini and V. Consonni, Handbook of Molecular Descriptors. John Wiley & Sons, 2008, p. 688. [9] Recent Advances in QSAR Studies: Methods and Applications. Springer Science & Business Media, 2010, p. 427. [10] S. R. Johnson and W. Zheng, “Recent progress in the computational prediction of aqueous solubility and absorption.,” AAPS J., vol. 8, no. 1, pp. E27–40, Jan. 2006. [11] L. Nasri, S. Bensaad, and Z. Bensetiti, “Correlation and Prediction of the Solubility of Solid Solutes in Chemically Diverse Supercritical Fluids Based on the Expanded Liquid Theory,” Adv. Chem. Eng. Sci., vol. 03, no. 04, pp. 255–273, Sep. 2013. [12] “Samuel Yalkowsky, PhD | College of Pharmacy - University of Arizona.” [Online]. Available: http://www.pharmacy.arizona.edu/directory/samuel-yalkowsky-phd. [Accessed: 12-Jul-2014].
ABSTRACT: Values education is the process by a which people transmit values to others. It can be an activity that can take place in any organisation during which people are assisted by others, who may be older, in a position of authority or are more experienced, to make explicit those values underlying their own behaviour, to assess the effectiveness of these values and associated behaviour for their own and others' long term well-being and to reflect on and acquire other values and behaviour which they recognise as being more effective for long term well-being of self and others. Values education can take place at home, as well as in schools, colleges, universities, jails and voluntary youth organisations. There are two main approaches to values education, some see it as inculcating or transmitting a set of values which often come from societal or religious rules or cultural ethics while others see it as a type of Socratic dialogue . Where people are gradually brought to their own realisation of what is good behaviour for themselves and their community. DefinitionsThere has been very little reliable research on the results of values education classes, but there are some encouraging preliminary results. One definition refers to it as the process that gives young people an initiation into values, giving knowledge of the rules needed to function in this mode of relating to other people, and to seek the development in the student a grasp of certain underlying principles, together with the ability to apply these rules intelligently, and to have the settled disposition to do so, Some researchers use the concept values education as an umbrella of concepts that includes moral education and citizenship education. . Themes that values education can address to varying degrees are character, moral development, Religious Education, Spiritual development, citizenship education, personal development, social development and cultural development. There is a further distinction between explicit values education and implicit values education, where:
Another definition of value education is "learning about self and wisdom of life" in a self exploratory, systematic and scientific way through formal education... Download 441.32 Kb. Share with your friends:
| |||||||||
