An assessment of nucleic acid amplification testing for active mycobacterial infection



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AFB = acid-fast bacilli; BAL = bronchoalveolar lavage; CSF = cerebrospinal fluid; FNA = fine-needle aspirate; NAAT = nucleic acid amplification test
Forest plot of the sensitivity and specificity <a href=of NAAT compared with culture, grouped according to use of in-house or commercial NAAT, for studies conducted in countries with low and medium incidence of TB" align="bottom" width="932" height="497" border="0">

Figure 41 Forest plot of the sensitivity and specificity of NAAT compared with culture, grouped according to use of in-house or commercial NAAT, for studies conducted in countries with low and medium incidence of TB

Incidence of TB based on WHO estimates from 2012: low incidence = ≤ 10 cases per 100,000 people; medium incidence = 10–100 cases per 100,000 people

NAAT = nucleic acid amplification test; TB = tuberculosis



Forest plot of the sensitivity and specificity of NAAT compared with culture, grouped according to use of in-house or commercial NAAT, for studies conducted in countries with high incidence of TB

Figure 42 Forest plot of the sensitivity and specificity of NAAT compared with culture, grouped according to use of in-house or commercial NAAT, for studies conducted in countries with high incidence of TB



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