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Malaria prevention practices and delivery outcome: a cross sectional study of pregnant women attending a tertiary hospital in northeastern Nigeria



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Malaria prevention practices and delivery outcome: a cross sectional study of pregnant women attending a tertiary hospital in northeastern Nigeria


Malaria in pregnancy remains a public health problem in Nigeria. It causes maternal anaemia and adversely affects birth outcome leading to low birth weight, abortions and still births. Nigeria has made great s...

Hamzat U. Muhammad, Fatima J. Giwa, Adebola T. Olayinka, Shakir M. Balogun, IkeOluwapo Ajayi, Olufemi Ajumobi and Patrick Nguku

Malaria Journal 2016 15:326

Sharp increase of imported Plasmodium vivax malaria seen in migrants from Eritrea in Hamburg, Germany


Since 2014, a considerable increase in Plasmodium vivax malaria has been observed in Germany. The majority of cases was seen in Eritrean refugees.

Louise Roggelin, Dennis Tappe, Bernd Noack, Marylyn M. Addo, Egbert Tannich and Camilla Rothe

Malaria Journal 2016 15:325

Evaluation of a topical formulation of eprinomectin against Anopheles arabiensis when administered to Zebu cattle (Bos indicus) under field conditions


Although vector control strategies, such as insecticide-treated bed nets (ITNs) and indoor residual spraying (IRS) have been effective in Kenya the transmission of malaria continues to afflict western Kenya. T...

Saul Lozano-Fuentes, Rebekah C. Kading, Daniel A. Hartman, Edward Okoth, Naftaly Githaka, Vishvanath Nene and Richard M. Poché

Malaria Journal 2016 15:324

Plasmodium Rab5b is secreted to the cytoplasmic face of the tubovesicular network in infected red blood cells together with N-acylated adenylate kinase 2


Rab5 GTPase regulates membrane trafficking between the plasma membrane and endosomes and harbours a conserved C-terminal isoprenyl modification that is necessary for membrane recruitment. Plasmodium falciparum en...

Kazuo Ebine, Makoto Hirai, Miako Sakaguchi, Kazuhide Yahata, Osamu Kaneko and Yumiko Saito-Nakano

Malaria Journal 2016 15:323

Plasmodium vivax infection: a major determinant of severe anaemia in infancy


Most malarious countries outside of Africa are co-endemic for Plasmodium falciparum and Plasmodium vivax. The comparative burden of anaemia in the community caused by these two species is incompletely characteriz...

Enny Kenangalem, Muhammad Karyana, Lenny Burdarm, Shunmay Yeung, Julie A. Simpson, Emiliana Tjitra, Nicholas M. Anstey, Jeanne Rini Poespoprodjo, Ric N. Price and Nicholas M. Douglas

Malaria Journal 2016 15:321

Post-deployment effectiveness of malaria control interventions on Plasmodium infections in Madagascar: a comprehensive phase IV assessment


Because international funding for malaria control is plateauing, affected countries that receive foreign funding are expected to maintain a constant budget while continuing to reduce Plasmodium transmission. To i...

Thomas Kesteman, Milijaona Randrianarivelojosia, Patrice Piola and Christophe Rogier

Malaria Journal 2016 15:322

Building malaria out: improving health in the home


Malaria prevalence has halved in endemic Africa since 2000, largely driven by the concerted international control effort. To achieve the new global targets for malaria control and elimination by 2030, and to s...

Lucy S. Tusting, Barbara Willey and Jo Lines

Malaria Journal 2016 15:320

Erratum to: Epidemiologic features of overseas imported malaria in the People’s Republic of China


Zhongjie Li, Qian Zhang, Canjun Zheng, Sheng Zhou, Junling Sun, Zike Zhang, Qibin Geng, Honglong Zhang, Liping Wang, Shengjie Lai, Wenbiao Hu, Archie C. A. Clements, Xiao-Nong Zhou and Weizhong Yang

Malaria Journal 2016 15:318



Plasmodium falciparum parasite population structure and gene flow associated to anti-malarial drugs resistance in Cambodia

Western Cambodia is recognized as the epicentre of emergence of Plasmodium falciparum multi-drug resistance. The emergence of artemisinin resistance has been observed in this area since 2008–2009 and molecular si...

Ankit Dwivedi, Nimol Khim, Christelle Reynes, Patrice Ravel, Laurence Ma, Magali Tichit, Christiane Bourchier, Saorin Kim, Dany Dourng, Chanra Khean, Pheaktra Chim, Sovannaroth Siv, Roger Frutos, Dysoley Lek, Odile Mercereau-Puijalon, Frédéric Ariey…

Malaria Journal 2016 15:319



Real-time measurement of Plasmodium falciparum-infected erythrocyte cytoadhesion with a quartz crystal microbalance

An important virulence mechanism of the malaria parasite Plasmodium falciparum is cytoadhesion, the binding of infected erythrocytes to endothelial cells in the second half of asexual blood stage development. Con...

Daniela Kömpf, Jana Held, Stefani F. Müller, Hartmut R. Drechsel, Serena C. Tschan, Hinnak Northoff, Benjamin Mordmüller and Frank K. Gehring

Malaria Journal 2016 15:317



Safety of a single low-dose of primaquine in addition to standard artemether-lumefantrine regimen for treatment of acute uncomplicated Plasmodium falciparum malaria in Tanzania

This study assessed the safety of the new World Health Organization (WHO) recommendation of adding a single low-dose of primaquine (PQ) to standard artemisinin-based combination therapy (ACT), regardless of in...

Richard Mwaiswelo, Billy E. Ngasala, Irina Jovel, Roland Gosling, Zul Premji, Eugenie Poirot, Bruno P. Mmbando, Anders Björkman and Andreas Mårtensson

Malaria Journal 2016 15:316



Prevalence of Plasmodium spp. in illegal gold miners in French Guiana in 2015: a hidden but critical malaria reservoir

Malaria is endemic in French Guiana, an overseas territory of France on the Guiana Shield. Since 2005, notified malaria cases are decreasing. However, new data show that malaria affects many Brazilian gold min...

Maylis Douine, Lise Musset, Florine Corlin, Stéphane Pelleau, Jérémie Pasquier, Louise Mutricy, Antoine Adenis, Felix Djossou, Paul Brousse, Frédérique Perotti, Helene Hiwat, Stephen Vreden, Magalie Demar and Mathieu Nacher

Malaria Journal 2016 15:315



Ecology of urban malaria vectors in Niamey, Republic of Niger

Urbanization in African cities has major impact on malaria risk. Niamey, the capital of the Republic of Niger, is situated in the West African Sahel zone. The short rainy season and human activities linked wit...

Rabiou Labbo, Thierry Fandeur, Isabelle Jeanne, Cyril Czeher, Earle Williams, Ibrahim Arzika, Amadou Soumana, Ramatoulaye Lazoumar and Jean-Bernard Duchemin

Malaria Journal 2016 15:314



Use of long-lasting insecticide-treated bed nets in a population with universal coverage following a mass distribution campaign in Uganda

Uganda conducted an LLIN mass distribution campaign in 2013 with the goal of achieving universal coverage. Using data from the 2014 malaria indicator survey, this analysis estimated the proportion of the popul...

Humphrey Wanzira, Henry Katamba and Denis Rubahika

Malaria Journal 2016 15:311



Low-grade sulfadoxine–pyrimethamine resistance in Plasmodium falciparum parasites from Lubango, Angola

Malaria is a major parasitic disease, affecting millions of people in endemic areas. Plasmodium falciparum parasites are responsible for the most severe cases and its resistance to anti-malarial drugs is notoriou...

Elsa P. S. Kaingona-Daniel, Larissa Rodrigues Gomes, Bianca E. Gama, Natália K. Almeida-de-Oliveira, Filomeno Fortes, Didier Ménard, Cláudio Tadeu Daniel-Ribeiro and Maria de Fátima Ferreira-da-Cruz

Malaria Journal 2016 15:309



Sub-Saharan red cell antigen phenotypes and glucose-6-phosphate dehydrogenase deficiency variants in French Guiana

The treatment of Plasmodium vivax infections requires the use of primaquine, which can lead to severe haemolysis in glucose-6-phosphate dehydrogenase (G6PD)-deficient individuals. However, most of the Latin Amer...

Florence Petit, Pascal Bailly, Jacques Chiaroni and Stéphane Mazières

Malaria Journal 2016 15:310



Experiences of households using integrated malaria prevention in two rural communities in Wakiso district, Uganda: a qualitative study

The integrated approach to malaria prevention which advocates use of several methods in a holistic manner is being explored to complement existing strategies. A pilot project that promoted integrated malaria p...

David Musoke, George Karani, Rawlance Ndejjo, Peter Okui and Miph Boses Musoke

Malaria Journal 2016 15:313



Hospitalization and ambulatory care in imported-malaria: evaluation of trends and impact on mortality. A prospective multicentric 14-year observational study

Hospitalization is usually recommended for imported malaria. The goal of the present study is to evaluate the evolution in clinical pathways while measuring their impact on mortality.

Enrique Casalino, Aurélie Etienne, France Mentré and Sandrine Houzé

Malaria Journal 2016 15:312



Challenges encountered by local health volunteers in early diagnosis and prompt treatment of malaria in Myanmar artemisinin resistance containment zones

After artemisinin resistance was reported, the Myanmar artemisinin resistance containment (MARC) project was initiated in 2011. One of the activities of MARC is to train volunteers for early diagnosis and pro...

Myat Htut Nyunt, Khin Myo Aye, Khin Thiri Kyaw, Soe Soe Han, Thin Thin Aye, Khin Thet Wai and Myat Phone Kyaw

Malaria Journal 2016 15:308



Factors associated with high heterogeneity of malaria at fine spatial scale in the Western Kenyan highlands

The East African highlands are fringe regions between stable and unstable malaria transmission. What factors contribute to the heterogeneity of malaria exposure on different spatial scales within larger foci h...

Amrish Y. Baidjoe, Jennifer Stevenson, Philip Knight, William Stone, Gillian Stresman, Victor Osoti, Euniah Makori, Chrispin Owaga, Wycliffe Odongo, Pauline China, Shehu Shagari, Simon Kariuki, Chris Drakeley, Jonathan Cox and Teun Bousema

Malaria Journal 2016 15:307



Immunogenetic markers associated with a naturally acquired humoral immune response against an N-terminal antigen of Plasmodium vivax merozoite surface protein 1 (PvMSP-1)

Humoral immune responses against proteins of asexual blood-stage malaria parasites have been associated with clinical immunity. However, variations in the antibody-driven responses may be associated with a ge...

Gustavo Capatti Cassiano, Adriana A. C. Furini, Marcela P. Capobianco, Luciane M. Storti-Melo, Maria E. Almeida, Danielle R. L. Barbosa, Marinete M. Póvoa, Paulo A. Nogueira and Ricardo L. D. Machado

Malaria Journal 2016 15:306



Severe anaemia associated with Plasmodium falciparum infection in children: consequences for additional blood sampling for research

Plasmodium falciparum infection may cause severe anaemia, particularly in children. When planning a diagnostic study on children suspected of severe malaria in sub-Saharan Africa, it w...

Laura Maria Francisca Kuijpers, Jessica Maltha, Issa Guiraud, Bérenger Kaboré, Palpouguini Lompo, Hugo Devlieger, Chris Van Geet, Halidou Tinto and Jan Jacobs

Malaria Journal 2016 15:304



Mass testing and treatment for malaria in low transmission areas in Amhara Region, Ethiopia

In areas with ongoing malaria transmission, strategies to clear parasites from populations can reduce infection and transmission. The objective of this paper was to describe a malaria mass testing and treatmen...

Callie A. Scott, Asnakew K. Yeshiwondim, Belendia Serda, Caterina Guinovart, Berhane H. Tesfay, Adem Agmas, Melkamu T. Zeleke, Girma S. Guesses, Asmamaw L. Ayenew, Worku M. Workie, Richard W. Steketee, Duncan Earle, Belay Bezabih and Asefaw Getachew

Malaria Journal 2016 15:305



Combating poor-quality anti-malarial medicines: a call to action

The circulation of poor-quality medicines continues to undermine the fight against many life-threatening diseases. Anti-malarial medicines appear to have been particularly compromised and present a major publi...

Quique Bassat, Marcel Tanner, Philippe J. Guerin, Kirstin Stricker and Kamal Hamed

Malaria Journal 2016 15:302



The biological function of antibodies induced by the RTS,S/AS01 malaria vaccine candidate is determined by their fine specificity

Recent vaccine studies have shown that the magnitude of an antibody response is often insufficient to explain efficacy, suggesting that characteristics regarding the quality of the antibody response, such as i...

Sidhartha Chaudhury, Christian F. Ockenhouse, Jason A. Regules, Sheetij Dutta, Anders Wallqvist, Erik Jongert, Norman C. Waters, Franck Lemiale and Elke Bergmann-Leitner

Malaria Journal 2016 15:301



Detection of Plasmodium using filter paper and nested PCR for patients with malaria in Sanliurfa, in Turkey

The objective of this study to detect Plasmodium and a subspecies of Plasmodium using filter paper in malaria endemic province, Sanliurfa, in Turkey, compare the results of nested PCR (nPCR) with microscopy for t...

Nebiye Yentur Doni, Fadile Yildiz Zeyrek and Adnan Seyrek

Malaria Journal 2016 15:299



Strengthening individual capacity in monitoring and evaluation of malaria control programmes to streamline M&E systems and enhance information use in malaria endemic countries

Malaria control interventions in most endemic countries have intensified in recent years and so there is a need for a robust monitoring and evaluation (M&E) system to measure progress and achievements. Providi...

Ashley Garley, Erin Eckert, Ali Sie, Maurice Ye, Keziah Malm, Edwin A. Afari, Mamadou Sawadogo, Samantha Herrera, Elizabeth Ivanovich and Yazoume Ye

Malaria Journal 2016 15:300



Encouraging impact following 2.5 years of reinforced malaria control interventions in a hyperendemic region of the Republic of Guinea

Malaria is one of the principal causes of morbidity and mortality in the Republic of Guinea, particularly in the highly endemic regions. To assist in malaria control efforts, a multi-component malaria control ...

Amanda Tiffany, Faya Pascal Moundekeno, Alexis Traoré, Melat Haile, Esther Sterk, Timothée Guilavogui, Blaise Genton, Micaela Serafini and Rebecca F. Grais

Malaria Journal 2016 15:298



Erratum to: K13 mutations and pfmdr1 copy number variation in Plasmodium falciparum malaria in Myanmar

Aye A. Win, Mallika Imwong, Myat P. Kyaw, Charles J. Woodrow, Kesinee Chotivanich, Borimas Hanboonkunupakarn and Sasithon Pukrittayakamee

Malaria Journal 2016 15:297

Sustained efficacy of artesunate-sulfadoxine-pyrimethamine against Plasmodium falciparum in Yemen and a renewed call for an adjunct single dose primaquine to clear gametocytes

In Yemen, artesunate plus sulfadoxine-pyrimethamine (AS + SP) has been used as first-line treatment for uncomplicated falciparum malaria, which accounts for about 99 % of malaria cases. There is evidence that ...

Wahib M. Atroosh, Hesham M. Al-Mekhlafi, Georges Snounou, Adel Al-Jasari, Hany Sady, Nabil A. Nasr, Yee-Ling Lau and Johari Surin

Malaria Journal 2016 15:295



Asymptomatic Plasmodium infections in 18 villages of southern Savannakhet Province, Lao PDR (Laos)

A large fraction of Plasmodium infections do not cause clinical signs and symptoms of disease and persist at densities in blood that are not detectable by microscopy or rapid diagnostic tests. These infections ma...

Koukeo Phommasone, Bipin Adhikari, Gisela Henriques, Tiengkham Pongvongsa, Panom Phongmany, Lorenz von Seidlein, Nicholas J. White, Nicholas P. J. Day, Arjen M. Dondorp, Paul N. Newton, Mallika Imwong and Mayfong Mayxay

Malaria Journal 2016 15:296



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