Population pharmacokinetic properties of artemisinin in healthy male Vietnamese volunteers
Artemisinin-based combination therapy is recommended as first-line anti-malarial treatment worldwide. A combination of artemisinin with the long acting drug piperaquine has shown high efficacy and tolerabilit...
Sofia Birgersson, Pham Van Toi, Nguyen Thanh Truong, Nguyen Thi Dung, Michael Ashton, Tran Tinh Hien, Angela Abelö and Joel Tarning
Malaria Journal 2016 15:90
Synergistic anti-malarial action of cryptolepine and artemisinins
Cryptolepine (CPE) is the major indoloquinoline isolated from the popular West African anti-malarial plant, Cryptolepis sanguinolenta. CPE possesses various pharmacological activities with potent anti-malarial ac...
Arnold D. Forkuo, Charles Ansah, Kwesi M. Boadu, Johnson N. Boampong, Elvis O. Ameyaw, Ben A. Gyan, Andrea T. Arku and Michael F. Ofori
Malaria Journal 2016 15:89
Timing of malaria in pregnancy and impact on infant growth and morbidity: a cohort study in Uganda
Malaria in pregnancy (MiP) is a major cause of fetal growth restriction and low birth weight in endemic areas of sub-Saharan Africa. Understanding of the impact of MiP on infant growth and infant risk of malar...
Pierre De Beaudrap, Eleanor Turyakira, Carolyn Nabasumba, Benon Tumwebaze, Patrice Piola, Yap Boum II and Rose McGready
Malaria Journal 2016 15:92
Identification of blood meal sources in the main African malaria mosquito vector by MALDI-TOF MS
The identification of blood meal sources in malaria vectors is critical to better understanding host/vector interactions and malaria epidemiology and control. Currently, the identification of mosquito blood me...
Sirama Niare, Jean-Michel Berenger, Constentin Dieme, Ogobara Doumbo, Didier Raoult, Philippe Parola and Lionel Almeras
Malaria Journal 2016 15:87
Fake anti-malarials: start with the facts
This meeting report presents the key findings and discussion points of a 1-day meeting entitled ‘Fake anti-malarials: start with the facts’ held on 28th May 2015, in Geneva, Switzerland, to disseminate the fin...
Harparkash Kaur, Siȃn Clarke, Mirza Lalani, Souly Phanouvong, Philippe Guérin, Andrew McLoughlin, Benjamin K. Wilson, Michael Deats, Aline Plançon, Heidi Hopkins, Debora Miranda and David Schellenberg
Malaria Journal 2016 15:86
Malaria, a parasite vector-borne disease, is one of the biggest health threats in tropical regions, despite the availability of malaria chemoprophylaxis. The emergence and rapid extension of Plasmodium falciparum
Tiphaine Gaillard, Jérôme Dormoi, Marylin Madamet and Bruno Pradines
Malaria Journal 2016 15:85
Effectiveness of malaria control interventions in Madagascar: a nationwide case–control survey
Madagascar, as other malaria endemic countries, depends mainly on international funding for the implementation of malaria control interventions (MCI). As these funds no longer increase, policy makers need to k...
Thomas Kesteman, Milijaona Randrianarivelojosia, Vaomalala Raharimanga, Laurence Randrianasolo, Patrice Piola and Christophe Rogier
Malaria Journal 2016 15:83
Cost-effectiveness analysis of rapid diagnostic tests for G6PD deficiency in patients with Plasmodium vivax malaria in the Brazilian Amazon
The use of primaquine (PQ) for radical treatment of Plasmodium vivax in carriers of G6PD deficiency (G6PDd) constitutes the main factor associated with severe haemolysis in G6PDd. The current study aimed to estim...
Henry M. Peixoto, Marcelo A. M. Brito, Gustavo A. S. Romero, Wuelton M. Monteiro, Marcus V. G. de Lacerda and Maria R. F. de Oliveira
Malaria Journal 2016 15:82
Malaria in children of Tshimbulu (Western Kasai, Democratic Republic of the Congo): epidemiological data and accuracy of diagnostic assays applied in a limited resource setting
The literature data on malaria in Western Kasai, DRC, are limited and inadequate. A recent molecular survey there has detected Plasmodium ovale and Plasmodium malariae as mixed infections with Plasmodium falcipar...
Simona Gabrielli, Livia Bellina, Giovanni Luigi Milardi, Boniface Kabasele Katende, Valentina Totino, Valerio Fullin and Gabriella Cancrini
Malaria Journal 2016 15:81
Spatial heterogeneity of malaria in Ghana: a cross-sectional study on the association between urbanicity and the acquisition of immunity
Malaria incidence has declined considerably over the last decade. This is partly due to a scale-up of control measures but is also attributed to increasing urbanization. This study aimed to analyse the associa...
Clemens Frank, Ralf Krumkamp, Nimako Sarpong, Peter Sothmann, Julius N Fobil, Geoffrey Foli, Anna Jaeger, Lutz Ehlkes, Ellis Owusu-Dabo, Yaw Adu-Sarkodie, Florian Marks, Ralf R. Schumann, Jürgen May and Benno Kreuels
Malaria Journal 2016 15:84
Genetic diversity among Plasmodium vivax isolates along the Thai–Myanmar border of Thailand
Knowledge of the population genetics and transmission dynamics of Plasmodium vivax is crucial in predicting the emergence of drug resistance, relapse pattern and novel parasite phenotypes, all of which are releva...
Sarunya Maneerattanasak, Panita Gosi, Srivicha Krudsood, Jarinee Tongshoob, Charlotte A. Lanteri, Georges Snounou and Srisin Khusmith
Malaria Journal 2016 15:75
Widespread distribution of Plasmodium vivax malaria in Mauritania on the interface of the Maghreb and West Africa
Plasmodium vivax is very rarely seen in West Africa, although specific detection methods are not widely applied in the region, and it is now considered to be absent from North Africa. ...
Hampâté Ba, Craig W. Duffy, Ambroise D. Ahouidi, Yacine Boubou Deh, Mamadou Yero Diallo, Abderahmane Tandia and David J. Conway
Malaria Journal 2016 15:80
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