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Course Code: PHT1096
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Course Title: Cosmetic Delivery Systems
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Credits = 3
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L
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T
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P
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Semester:
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Total contact hours: 45 Hrs
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2
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1
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0
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List of Prerequisite Courses
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NIL
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List of Courses where this course will be prerequisite
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NIL
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Description of relevance of this course in the B. Tech (Pharma)
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To train the students with respect to basics and advances of cosmetic delivery systems
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Course Contents (Topics and subtopics)
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Reqd. hours
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1.
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Introduction to cosmetic delivery systems and cosmeceuticals and basic consideration:
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Definition of cosmeceuticals
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Advantages
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Market overview
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Current trends in cosmeceuticals w.r.t. nanotechnology and delivery platforms
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5
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2
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Vesicular Delivery systems (Introduction, Formulation, applications and advances):
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Liposomes
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Transferosomes
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Niosomes
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Phytosomes
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Miscellaneous vesicular systems
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8
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3
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Particulate Systems (Introduction, Formulation, applications and advances):
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Porous polymeric systems
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Polymeric micro/ nanoparticulate systems
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8
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4
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Emulsion Delivery Systems (Introduction, Formulation, applications and advances):
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Colloidal delivery systems
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Micro/nano and multiple emulsions
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Liquid crystals
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8
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5
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Other Delivery systems (Introduction, Formulation, applications and advances):
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Cyclodextrin complexes
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Carbosomes
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Dendrimers
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Nano Crystals
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8
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6
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Delivery Devices (Introduction, Formulation, applications and advances):
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Iontophoresis
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Microneedles
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Cosmetic patches
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8
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List of Text Books/ Reference Books
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Recent research and review articles from literature
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Advances in dermatological Sciences, 2013, R. P. Chilcott, Keith R. Brain, Royal Society of Chemistry
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Harry’s Cosmeticology, Rieger 8th edition, 2000, Leonard Hill Book & Intertext Publisher, London
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Course Outcomes (students will be able to…..)
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1
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Explain concept of cosmetic delivery systems and cosmeceuticals
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2
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Explain recent advances in cosmeceuticals
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Course Code: PHT1097
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Course Title: Applied Molecular Biotechnology
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Credits = 3
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L
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T
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P
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Semester: VII
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Total contact hours: 45
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2
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1
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0
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List of Prerequisite Courses
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Molecular Biology and Biotechnology
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List of Courses where this course will be prerequisite
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None
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Description of relevance of this course in the B. Tech./B.Pharm. Program
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To Introduce students to advanced genetic techniques employed to design molecular diagnostic kits and protein therapeutics and to familiarize students with the procedures involved in genetic engineering of plants and animals
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Sr. No.
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Course contents (topics and subtopics)
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Reqd. hours
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1
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Molecular diagnostics: Immunological diagnostic procedures, nucleic acid diagnostic systems, molecular diagnosis of genetic disease
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5
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2
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Protein therapeutics: Biopharmaceuticals, enzymes, monoclonal and recombinant antibodies
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5
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3
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Nucleic acids as therapeutic agents
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5
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4
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Vaccines: Subunit vaccines, peptide vaccines, DNA vaccines, attenuated vaccines
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5
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5
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Synthesis of commercial products by recombinant microorganisms: Enzymes, antibiotics, biopolymers; synthetic biology routes for biopharmaceuticals
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5
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6
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Large-scale production of proteins from recombinant microorganisms
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5
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7
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Bioremediation and biomass utilization: Microbial degradation of xenobiotics, genetic engineering of biodegradative pathways, utilization of starch, sugars and cellulose
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5
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8
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Genetic engineering of plants
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5
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9
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Transgenic animals
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5
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List of Text Books/Reference Books
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1
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Molecular Biotechnology: Principles and Applications of Recombinant DNA, by Glick and Paternak 3rd edition, 2003, ASM Press
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2
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Principles of gene manipulation : an introduction to genetic engineering / R.W. Old, S.B. Primrose, 5th Edition, 1994, Blackwell Scientific
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3
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Gene Cloning and DNA Analysis: An Introduction, T A Brown, 7th Edition, 2015, Wiley-Blackwell
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Course Outcomes (students will be able to )
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1
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Describe the procedures involved in designing molecular diagnostic kits
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2
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Design strategies to synthesize biological products using recombinant microbial host cells
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3
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Use the knowledge of microbial metabolic processes to carry out genetic engineering of microbes to degrade recalcitrant material
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4
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Apply different protocols available for genetic engineering of plants and animals
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Course Code: PHT1098
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Course Title: Biomaterials: Biodegradable Materials for Biomedical Applications
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Credits = 3
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L
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T
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P
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Semester:
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Total contact hours: 45
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2
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1
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0
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List of Prerequisite Courses
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10th std. Biology; 12th std Chemistry, 12th standard Physics
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List of Courses where this course will be prerequisite
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NA
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Description of relevance of this course in the B. Tech./B.Pharm. Program
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This class provides an introduction to the interactions between cells and the surfaces of biomaterials. The course covers: surface chemistry and physics of selected metals, polymers, and ceramics; surface characterization methodology; modification of biomaterials surfaces; quantitative assays of cell behavior in culture; biosensors and microarrays; bulk properties of implants; and acute and chronic response to implanted biomaterials. General topics include biosensors, drug delivery, and tissue engineering.
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Sr. No.
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Course contents (Topics and subtopics)
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Reqd. hours
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1
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Introduction of Biomaterials
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2
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2
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Biomaterials Surfaces:
Structure and Properties, Surface Energy, Adsorption and Reconstruction at Surfaces
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4
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3
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Protein-Surface Interactions:
Proteins: Structure, Properties, Functions, Protein Adsorption: Complex Phenomena, Measurement
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4
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4
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Cell-Surface Interactions: Host Response to Biomaterials:
Cell adhesion mechanism, coagulation cascade, immune response
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4
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5
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Surface Characterization:
AES, XPS, AFM, Contact Angle
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2
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6
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Quantifying Cell Behavior:
Cell Culture, Cellular Assays
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2
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7
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Biosensors and Diagnostic devices
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2
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8
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Drug Delivery:
Controlled Release, Diffusion Controlled and Membrane based devices, Mechanical Pumps
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3
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9
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Biomaterial for Organ Replacement
Mechanical Properties, Bone Substitutes
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3
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10
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Introduction of Tissue Engineering:
Cell, Scaffold design, Artificial liver, pancreas, cartilage
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2
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11
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Regulatory overview
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2
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List of Text Books/Reference Books
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1
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Ratner, Buddy D., et al. Biomaterials Science: An Introduction to Materials in Medicine. 2nded. Burlington, MA: Academic Press, 2004. ISBN: 9780125824637
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Course Outcomes (students will be able to )
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1
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Apply engineering principles to understand and predict the behavior of biological and physiological systems relevant to human health and disease
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2
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Explicate and employ theory of biomedical engineering design and technology creation
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3
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Explicate and exploit various biomaterials and their properties
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4
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Elucidate protein biomaterial interactions
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5
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Explain and apply characterization methods for biomaterials and biomaterial-protein interactions
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