Israel state records י"ב באדר התשס"ו March 12, 2006



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[57] A method for identifying or cloning nucleic acids comprising sequences corresponding to portions of genes that are differentially spliced or altered between two samples containing nucleic acids, said method comprising:

(a) hybridizing a plurality of different RNAs or double-stranded cDNAs derived from a first sample with a plurality of different cDNAs derived from a second sample; and

(b) identifying or cloning, from the hybrids formed in (a), nucleic acids comprising an unpaired region, said cloned or identified nucleic acids comprising a sequence corresponding to portions of genes that are differentially spliced or altered between said samples.

__________





138343

[21][11]

תהליך להכנת נגזרות של ניטרוגואנידין


PROCESS FOR THE PREPARATION OF NITROGUANIDINE DERIVATIVES


[54]




17.03.1999

[22]




CH

[33]

19.03.1998

[32]

649/98

[31]

Int. Cl.7 C07D 213/61, 213/89, 273/00, 273/04, 277/32, 285/15, 307/06, 413/12, 417/12

[51]




SYNGENTA PARTICIPATIONS AG, SWITZERLAND

[71]




WO/1999/047520

[87]

לוצאטו את לוצאטו,

גן תעשיה, עומר , ת.ד. 5352, באר שבע



LUZZATTO & LUZZATTO,

P.O.B. 5352

BEER-SHEVA 84965


[74]










[57] Process for the production of a compound of the formula



wherein R1 is hydrogen or C1-C4 alkyl;

R2 is hydrogen, C1-C6-alkyl, C2-C6-alkenyl, C2-C6-alkinyl, C3-C6cycloalkyl or a radical –CH2B;

A is selected from the group consisting of 2-chloropyrid-5-yl, tetrahydrofuran-3-yl, 5-methyl-tetrahydrofuran-3-yl or 2-chlorothiazol-5-yl; and

B is phenyl, 3-pyridyl or thiazolyl, which are optionally substituted by one to three substituents selected from the group consisting of C1-C3-alkyl, C1-C3-halogenalkyl, cyclopropyl, halogencyclopropyl, C2-C3-alkenyl, C2-C3-alkinyl, C1-C3-alkoxy, C2-C3-halogenalkenyl, C2-C3-halogenalkinyl, C1-C3-halogenalkoxy, C1-C3-alkylthio, C1-C3-halogenalkylthio, allyloxy, propargyloxy, allylthio, propargylthio, halogenallyloxy, halogenallylthio, halogen, cyano or nitro; and optionally the possible E/Z isomers, E/Z isomeric mixtures or tautomers thereof, respectively in free form or in salt form; characterized in that a compound of the formula






wherein R1, R2 and A have the same significances as in formula (I), and X is O or S; is hydrolysed with a strong acid at a pH below 2; at a temperature between 50 and 100˚C; and in a solvent selected from the group consisting of water, alcohols, ethers or mixtures thereof.

__________




138344

[21][11]

שיטה לשרות משתמשי IP באמצעות אינטראקציה גרפית עם סוכנים של מוקד טלפוני


METHOD FOR SERVING IP USERS BY GRAPHICALLY BASED INTERACTION TO AGENTS OF A CALL CENTER


[54]




18.01.2000

[22]




US

[33]

20.01.1999

[32]

233818

[31]

Int. Cl.7 H04L 012/56, H04M 003/51, 007/00

[51]

תדיראן טלקום מערכות עסקיות בע"מ, פתח תקוה

TADIRAN TELECOM BUSINESS SYSTEMS LTD.

[71]




WO/2000/044159

[87]

אי. סי. איי. טלקום בע"מ,

רחוב הסיבים30, פתח תקוה



ECI TELECOM LTD,

30 HASIVIM ST.

PETACH TIKVA 49517


[74]




[57] A method for connecting IP users to agents being customer services representatives of a call-center, comprising transferring visual information about at least one of the following: the details of previous connections to the IP user, current quality of service, available resources and agents' details, prior to call establishment, and establishing a call according to inputs from said IP user which are responsive to said information.


__________



138378

[21][11]

שיטה להתקשרות בחזרה עבור מערכות תקשורת טלפון


CALL-BACK METHOD FOR TELEPHONE COMMUNICATION SYSTEMS


[54]




10.03.1999

[22]




NL

[33]

11.03.1998

[32]

1008563

[31]

Int. Cl.7 H04Q 007/24

[51]




PRIVACOM B.V., THE NETHERLANDS

[71]




WO/1999/046944

[87]

סנפורד ט. קולב ושות',,

שער הגיא 4, מרמורק , ת.ד. 2273, רחובות



SANFORD T.COLB & CO.,

P.O.B. 2273,

REHOVOT


[74]




[57] Call back method in a communication system comprising one or more exchanges and a number of terminals such as telephone sets, facsimile apparatuses, etc., each of which being able to communicate through at least one of said exchanges with at least one of said other terminals, whereby at least part of the terminals comprises a buffer circuit for storing the number of a terminal to be called, as well as an electronic circuit for controlling the call back method according to which method the following steps are performed, by the user:

(a) storing the number of the called terminal in said buffer, by the electronic circuit;

(b) establishing a connection at least partly through wireless paths with a predetermined exchange;

(c) transmitting signals to the exchange indicating that the terminal has to be called back;

(d) breaking the connection and waiting for the exchange to call back;

(e) as the connection is re-established retrieving the stored number from the buffer and transmitting it to the exchange;

(f) waiting for the exchange to establish the connection between the called terminal and the calling terminal and switching over to control of the terminal by the user.

__________




138467

[21][11]

תכשירי רוקחות המכילים קסיליטול\קסילוז


PHARMACEUTICAL COMPOSITIONS CONTAINING XYLITOL/XYLOSE


[54]




24.03.1999

[22]




US

[33]

24.03.1998

[32]

60/079184

[31]




US




23.12.1998




220283




Int. Cl.7 A61K 009/00, C07C 031/18, C07H 003/00

[51]




ALONZO H. JONES, U.S.A.

[71]




WO/1999/048361

[87]

וולף, ברגמן וגולר,

רחוב קרן היסוד 19ב' , ת.ד. 1352, ירושלים



WOLFF, BREGMAN AND GOLLER,

19B KEREN HAYESOD ST.

P.O.B. 1352,

JERUSALEM 91013



[74]




[57] A composition for nasal administration for use in treatment of nasal congestion, recurrent sinus infections, infection or inflammation associated with bacteria, or asthma triggered by upper respiratory inflammation, the composition comprising a xylitol/xylose solution as active ingredient therein in combination with a pharmaceutically acceptable carrier.

__________





138599

[21][11]

מערכת הזרקת תרופת בעלת בקרת לחץ/ עוצמה וכדומה


PRESSURE/FORCE COMPUTER CONTROLLED DRUG DELIVERY SYSTEM AND THE LIKE


[54]




05.03.1999

[22]




US

[33]

10.04.1998

[32]

60/081388

[31]




US




30.11.1998




201464




Int. Cl.7 A61M 005/172, 031/00

[51]




MILESTONE SCIENTIFIC, INC., U.S.A.

[71]




WO/1999/052575

[87]

סנפורד ט. קולב ושות',,

שער הגיא 4, מרמורק , ת.ד. 2273, רחובות



SANFORD T.COLB & CO.,

P.O.B. 2273,

REHOVOT


[74]










[57] An electronic device (10) for selectively injecting or withdrawing fluid from a patient's body comprising: a reservoir (90) for holding said fluid; a fluid delivery section having a first end coupled to said reservoir and a second end (16, 17) adapted for insertion into said body;

an electrical drive mechanism (12) arranged and constructed to apply a force within said reservoir in response to commands in either a first direction in which fluid is injected from said reservoir through said fluid delivery system and a second direction in which fluid is withdrawn through said fluid delivery system into said reservoir; a sensor for sensing an internal parameter indicative of a force generated by said drive mechanism and internal resistances within said reservoir and said fluid delivery system to said force; and a controller (18) coupled to said sensor, said controller including a calculator for calculating an entry/exit pressure at said second end as a function of said internal parameter, said controller generating said commands in accordance with said entry/exit pressure.




__________



138786

[21][11]

התקן עזר כירורגי


SURGERY ASSISTING DEVICE


[54]




29.09.2000

[22]

Int. Cl.7 A61B 017/00, 019/00

[51]

אברהם שפירר, רמת גן

AVRAHAM SPIERER

[71]

ריינהולד כהן ושותפיו,

רחוב אחד העם 21 , ת.ד. 4060, תל אביב



REINHOLD COHN AND PARTNERS,

21 AHAD HA'AM ST.,

P.O.BOX 4060,

TEL AVIV 61040



[74]




[57] A surgical assisting device (10), the device comprising a base member (12) fixedly mountable on a bed and at least one arm bracket (30) fixedly extending from the base member; at least one arm having a first end (32) clampingly fixable to any one of the at least one arm bracket at a fixed position, and a second end fitted with a surgical tool grip (36); said arm being manually manipulable such that the second end of the arm can acquire and retain any location and position.


__________





138887

[21][11]

שימוש ברבוקסטין להכנת תרופות לטיפול להפרעות עצבים


USE OF REBOXETINE FOR PREPARATION OF MEDICAMENTS FOR TREATING NERVOUS DISORDERS


[54]




02.04.1999

[22]




US

[33]

13.04.1998

[32]

60/081632

[31]




IT




23.04.1998




MI98A000870







US




11.05.1998




60/085033




Int. Cl.7 A61K 031/00, 031/5375, A61P 025/22, C07D 265/30

[51]



PHARMACIA & UPJOHN COMPANY LLC, U.S.A.

PHARMACIA & UPJOHN S.P.A, ITALY



[71]




WO/1999/052518

[87]

איתן, פרל, לצר וכהן צדק,

רחוב שנקר 7 , ת.ד. 12688, הרצליה



EITAN, PEARL, LATZER AND COHEN ZEDEK,

P.O.B. 12688,

HERZLIYA 46733


[74]




[57] The use of reboxetine or a pharmaceutically acceptable salt thereof for the manufacture of a medicament for use in the treatment of obsessive compulsive disorders (OCD) and/or panic disorder (PD) and/or the symptoms of either of these disorders.

__________



138919

[21][11]

שימוש של אנטגוניסטים של NMDA להכנת תרופות לטיפול בסינדרום מעי מגורה


USE OF NMDA ANTAGONISTS FOR PREPARATION OF MEDICAMENTS FOR TREATMENT OF IRRITABLE BOWEL SYNDROME


[54]




28.04.1999

[22]




SE

[33]

28.04.1998

[32]

9801494-7

[31]




SE




18.11.1998




9803954-8




Int. Cl.7 A61K 045/00, 045/06, C07D 237/06

[51]




ASTRAZENECA AB, SWEDEN

[71]




AZIZ ASGHAR, JOSE LUIS CABERO, ANDREW DRAY, ANNE KING

[72]




WO/1999/055323

[87]

לוצאטו את לוצאטו,

גן תעשיה, עומר , ת.ד. 5352, באר שבע



LUZZATTO & LUZZATTO,

P.O.B. 5352

BEER-SHEVA 84965


[74]





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