Title: Journal of General Microbiology

Title: Journal of General Physiology

ISO Abbreviated Title:

JCR Abbreviated Title:

ISSN: 0022-1295

Issues/Year:

Journal Country/Territory:

Language: English

Publisher: Rockefeller Univ Press

Publisher Address: 1114 First Ave, 4th Fl, New York, NY 10021

Subject Categories:

Physiology:

? Northrop, J.H. (1923), The inactivation of trypsin. IV. The adsorption of trypsin by charcoal. Journal of General Physiology, 5 (6), 751-755.

Full Text: -1959\J Gen Phy5, 751.pdf

? Abramson, H.A. (1929), Electrokinetic phenomena. I. The adsorption of serum proteins by quartz and paraffin oil. Journal of General Physiology, 13 (2), 169-177.

Full Text: -1959\J Gen Phy13, 169.pdf

? Krueger, A.P. (1931), The sorption of bacteriophage by living and dead susceptible bacteria. I. Equilibrium conditions. Journal of General Physiology, 14 (4), 493-516.

Full Text: -1959\J Gen Phy14, 493.pdf

? Palmer, A.H. (1932), The adsorption of gelatin by collodion membranes. Journal of General Physiology, 15 (5), 551-559.

Full Text: -1959\J Gen Phy15, 551.pdf

? Dow, P. (1936), The adsorption of egg albumin on collodion membranes. Journal of General Physiology, 19 (6), 907-916.

Full Text: -1959\J Gen Phy19, 907.pdf

? Langmuir, I. and Waugh, D.F. (1938), The adsorption of proteins at oil-water interfaces and artificial protein lipoid membranes. Journal of General Physiology, 21 (6), 745-755.

Full Text: -1959\J Gen Phy21, 745.pdf

? Delbrück, M. (1940), Adsorption of bacteriophage under various physiological conditions of the host. Journal of General Physiology, 23 (5), 631-642.

Full Text: -1959\J Gen Phy23, 631.pdf

? Henry, R.J. and Henry, M.D. (1945), The effect of penicillin on Methylene blue adsorption onto activated charcoal. Journal of General Physiology, 28 (5), 415-419.

Full Text: -1959\J Gen Phy28, 415.pdf

? Williams, H.B. and Choppin, A.R. (1950), Adsorption studies in a synthetic rubber latex ovalbumin system. Journal of General Physiology, 34 (2), 183-192.

Full Text: -1959\J Gen Phy34, 183.pdf

? Weber, A., Herz, R. and Reiss, I. (1963), On mechanism of relaxing effect of fragmented sarcoplasmic reticulum. Journal of General Physiology, 46 (4), 679-702.

Full Text: 1963\J Gen Phy46, 679.pdf

Abstract: The vesicles of fragmented sarcoplasmic reticulum, i.e. the physiological relaxing factor, remove most of the exchangeable Ca bound to actomyosin and myofibrils. The extent to which they remove Ca and the extent to which they inhibit myofibrillar activity are closely correlated. Previous work has shown that those in vitro reactions of actomyosin with ATP which are equivalent to its contraction, i.e. superprecipitation and a high ATPase activity, require the formation of a Ca-actomyosin complex, and that actomyosin after the removal of most of its bound Ca is inhibited by physiological concentrations of ATP. The evidence now suggests that the factor achieves its relaxing effect through the dissociation of the Ca-actomyosin complex and that it has no other direct influence on the biological activity of actomyosin. Experiments, showing that under similar conditions the vesicles of the factor are capable of reducing the concentration of ionized Ca in the surrounding medium to about 0.02 #M and less, suggest that the factor competes successfully with actomyosin for the available Ca through its mechanism of Ca accumulation.

? Hornung, D.E. and Mozell, M.M. (1977), Factors influencing differential sorption of odorant molecules across olfactory mucosa. Journal of General Physiology, 69 (3), 343-361.

Full Text: 1960-80\J Gen Phy69, 343.pdf

Abstract: By use of a flow dilution olfactometer, tritium-labeled odorants were presented through the external naris to the bullfrog’s intact olfactory sac. After stimulation the animal was frozen in liquid nitrogen. The dorsal surface and eminentia of the olfactory sac were then removed and sawed into sections perpendicular to the long axis of the mucosal surface. Each section was dissolved in a tissue solubilizer and counted in a liquid scintillation system. The amount of radioactivity in each section was used to estimate the number of odorant molecules it sorbed. For tritiated butanol there was a significant decrease in radioactivity from the section containing the external naris to that overhanging the internal naris. The steepness of the gradient was unaffected by a rather large range of stimulus flow rates, volumes, and partial pressures. Only when these parameters were pushed to extreme physical limits did this gradient change significantly. When the stimulus was presented through the internal rather than the external naris, the butanol gradient reversed its direction, decreasing from the internal to external. Unlike butanol, tritiated octane presented through the external naris was rather evenly distributed among the mucosal sections. That is, octane showed no distribution gradient across the mucosa. These results complement previous electrophysiological data that suggested a “chromatographic-like” differential sorption of odorant molecules across the mucosa.

Notes: highly cited

? Mclaughlin, S., Mulrine, N., Gresalfi, T., Vaio, G. and Mclaughlin, A. (1981), Adsorption of divalent cations to bilayer membranes containing phosphatidylserine. Journal of General Physiology, 77 (4), 445-473.

Full Text: 1981\J Gen Phy77, 445.pdf

Abstract: The Stern equation, a combination of the Langmuir adsorption isotherm, the Boltzmann relation, and the Grahame equation from the theory of the diffuse double layer, provides a simple theoretical framework for describing the adsorption of charged molecules to surfaces. The ability of this equation to describe the adsorption of divalent cations to membranes containing brain phosphatidylserine (PS) was tested in the following manner. Charge reversal measurements were first made to determine the intrinsic 1:1 association constants of the divalent cations with the anionic PS molecules: when the net charge of a PS vesicle is zero one-half of the available sites are occupied by divalent cations. The intrinsic association constant, therefore, is equal to the reciprocal of the divalent cation concentration at which the mobility of a PS vesicle reverses sign. The Stern equation with this association constant is capable of accurately describing both the zeta potential data obtained with PS vesicles at other concentrations of the divalent cations and the data obtained with vesicles formed from mixtures of PS and zwitterionic phospholipids. Independent measurements of the number of ions adsorbed to sonicated PS vesicles were made with a calcium-sensitive electrode. The results agreed with the zeta potential results obtained with multilamellar vesicles. When membranes are formed at 20~ in 0.1 M NaCI, the intrinisc 1 : 1 association constants of Ni, Co, Mn, Ba, Sr, Ca, and Mg with PS are 40, 28, 25, 20, 14, 12, and 8 M -1, respectively.

? Rossner, M., Van Epps, H. and Hill, E. (2008), Show me the data. Journal of General Physiology, 131 (1), 3-4.

Full Text: 2008\J Gen Phy131, 3.pdf