Phenylpropanolamine & risk of hemorrhagic stroke: Final Report of The Hemorrhagic Stroke Project


For non-enrolled subjects, stroke events were confirmed to be eligible but ability to communicate within 30 days of event was not assessed



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1For non-enrolled subjects, stroke events were confirmed to be eligible but ability to communicate within 30 days of event was not assessed.

Table 2.

Sociodemographic and Clinical Features

of Case and Control Subjects








Cases1

(n=702)


Controls

(n=1376)








No.

%

No.

%




Sociodemographic Features
















Female

383

55%

750

55%




Black race

146

21%

232

17%

*



















Age: < 40

296

42%

592

43%




40-49

406

58%

784

57%






















Education2:

143

20%

121

9%

*

High school graduate

280

40%

395

29%




College+

277

40%

860

62%






















Clinical Features
















Cigarette smoking: Current

358

51%

419

30%

*

Ex

150

21%

367

27%




Never

194

28%

590

43%




Hypertension (hx)2

272

39%

281

20%

*

Diabetes (hx)2

44

6%

72

5%




Primary family history2

51

9%

56

5%

*

Alcohol use (>2drinks/day)

95

14%

96

7%

*

Cocaine use3

12

2%

2

<1%

*

Oral contraceptive use4 (% women)

36

9%

74

10%






















Body mass index (wt/ht2)2: <24

233

33%

391

29%




24-30

295

42%

659

48%




>30

169

24%

322

23%






















URI symptoms (in two weeks)

114

17%

269

20%



*P-value (two-sided)<.05.



1Among the 709 enrolled subjects, 6 were excluded from the analysis (3 subjects had no controls identified; 2 subjects completed interviews more than 30 days after their stroke event; and the index date for 1 subject could not be determined).

2Missing or uncertain responses: Education (2 cases), hypertension (1 control), diabetes (5 cases and 2 controls), primary family history (137 cases and 246 controls), body mass index (5 cases and 4 controls), URI symptoms (39 cases and 54 controls).

3Current use (defined as use on ID or preceding day).

4Use in 3-day window.

Table 3.



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