Solid dosage forms
TYPES OF QUALITY CONTROL TESTS
Download 37.21 Kb.
|
- Navigate this page:
- NON-OFFICIAL TEST
- TYPES OF CAPSULES
| TYPES OF QUALITY CONTROL TESTS
There are 2 types of tests 1.CHEMICAL TEST: This test include the chemical content(potency), content uniformity test and purity test 2.PHYSICAL TEST: These are divided into two OFFICIAL TEST: this is the one prescribed in the official book and include wet variation, disintegration time and dissolution test. These are standard tests found in the official books NON-OFFICIAL TEST: These tests are not included in the official reference or books and include: uniformity of tablet diameter, stability test, crushing strength test, frability test CAPSULES Capsules are solid dosage forms. Each capsule is made up of two parts: Capsule shell and Drug. The shell is usually made up of gelatin material. In capsule, the amount of the drug may be small, therefore a diluent is needed to make up the bulk of the drug. TYPES OF CAPSULES There are 2 types of capsules: Hard gelatin capsule Soft gelatin capsule The capsule shell is made up of gelatin, sugars and water. The gelatin is usually obtained from animal skins and bones by hydrolysis. ADVANTAGES OF CAPSULES 1. Since the drug is enclosed in a shell, it is easy to mask unpleasant tastes and odour. 2. Usually, the drug is enclosed in a shell, therefore once it gets into a moist environment, the gelatin dissolves, hence there is fast release and onset of action. 3. The drug is in a shell, therefore protects the drug from the environmental conditions such as light, humidity etc. 4. Most capsules are elegant in appearance, therefore there is patient compliance. 5. Enteric coating can be applied to hard capsules. This coating protects the drug from gastric degradation. 6. The enteric coating in hard capsules also protects some drugs from the irritation of the GIT. 7. The capsule can also be coated to target where it is supposed to release a certain drug. Download 37.21 Kb. Share with your friends:
|