Sino-American Pharmaceutical Professionals Association-New England (sapa-ne)
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- Mr. Kechun Li Eisai Research Institute, SAPA-NE, 1999 Term President
- Amgen, Inc., SAPA-NE, 1999-2000 Term Director
- Soldiers Field Road, Boston, MA 02163
- “The Role of ADME/PK in Drug Discovery”
- “Success Factors in Technology Commercialization”
- Afternoon Session (Plenary Speeches and Penal Discussions)
- “New Drug Approval and Innovative Atmosphere in China”
- Guo Chungang, Assoc. Prof., the State Dept. Of Toxicology
- The New Medicines of the Future – Where Will They Come from
Sino-American Pharmaceutical Professionals Association-New England (SAPA-NE)
SAPA-New England 4th Annual Conference 2001 Drug Discovery: Industry Trends and Business Climate Co-organized by Harvard Business School Healthcare and Biotech Club Lead Sponsor: ArQule, Inc. In Part Sponsored by Northeastern Section of ACS PROGRAM June 8-9, 2001 Burden Hall Auditorium, Harvard Business School Soldiers Field Road Boston, MA 02163 Website: http://www.sapa-ne.org or
Conference Chair:
Conference Co-Chair and Section Chair:
Conference Organizing Committee:
Greetings from Conference ChairWelcome to SAPA-NE (Sino-American Pharmaceutical Professionals Association, New England Section) 4th Annual Conference: Drug Discovery: Industry Trends and Business Climate. Recent advances in genomics are bringing about a revolution in our understanding of the molecular mechanisms of disease and creating an explosive number of new biological targets for the development of new drugs. Fulfilling the promise of genomics, however, will require similar advances in the technology and systems used to discover and test small molecules interacting with these targets. Advances in drug discovery technologies hold the key to unlock the value of genomics. Things are changing more rapidly than ever. “High through-put lead optimization”, a relatively new term a few years ago, has become a popular phrase everywhere in our industry. If you believe the trend is clear, the classical questions are still here. How to optimize ADMET properties? How to interpret and handle the enormous information generated by our tremendous efforts? How to improve the efficiency of the discovery process? These are no simple questions and most importantly, people who discover the niche will be successful in their career endeavor. Have you heard the discovery story of Merck’s VIOXX, an anti-inflammatory drug and Celebrex’s rival? Dr. Peppi Prasit, the key scientist who is responsible for its discovery, got the idea from a local conference. “Although the compound (in the poster) wasn’t chemically fit in people. Dr. Prasit immediately went back to his lab, cooked up the mysterious molecule and put it to Merck’s new test…” Information exchange helps! SAPA-NE has organized this conference by bringing together leaders from east to west, who will share their experiences and discuss current trends and strategies in the drug discovery industry. Our program includes presentations from a variety of perspectives including senior management from the pharmaceutical and biotechnology industries, research scientists, and business development professionals. The conference also includes an exhibition of new products and technologies for drug discovery and a career fair. I encourage you to take advantage of this tremendous opportunity to hear the latest trends in drug discovery and get some ideas of significant innovations in the drug discovery process that address these challenges. SAPA is a federally registered non-profit organization striving to promote and facilitate the exchange of scientific information and to contribute to the whole society. On behalf of SAPA-NE, I’d like to take this opportunity to thank our speakers whose sole compensation is the satisfaction of the ultimate contribution to the improvement of well being of human beings. SAPA-NE is grateful to the lead sponsor, ArQule, Inc. and other corporate sponsors for their vision and strong support in many ways and for their generous funding to this conference and other SAPA-NE activities all year round. Special thanks go to NESACS and Harvard Business School Healthcare and Biotech Club for their shared value and support. And congratulations to you for your smart decision to participate this conference. I hope you will meet some outstanding leaders in our industry and make new friends at this conference. Together we can make a better world. Thank you very much. Jenny Li, Conference Chair President-elect, SAPA-NE
8:00 am - 9:00 am Registration 9:00 am - 12:00 am Morning Session 12:00 am –1:30 pm Lunch 1:30 pm - 5:30 pm Afternoon Session 5:30 pm - 6:30 pm Social hour 10:00 am - 5:30 pm Exhibition and Job Fair 6:30 pm - 8:00 pm Reception 8:00 pm – 9:30 pm Dinner
Secretary of Northeastern Section of ACS (NESACS) 9:00 am - 9:10 am Conference Chair’s Announcement, Jenny Li, President-elect of SAPA-NE, Staff Investigator, ArQule, Inc. Opening Remark: Dr. Tim B. Frigo, President of NESACS 9:10 am – 10:00 am Dr. Stephen A. Hill, President & CEO, ArQule, Inc. “The New Medicines of the Future - Where Will They Come From?” 10:00 am - 10:40 am Dr. Donna M. Huryn, Director, Department of Chemical Sciences, Wyeth-Ayerst Research, Princeton, NJ “Design and Synthesis of VLA-4 Antagonists” 10:40 am - 10:55 am Coffee Break 10:55 am - 11:35 am Dr. Maria Webb, VP of Discovery Biology, Pharmacopeia, Inc. “Applications and Successes of Large, Diverse Combinatorial Libraries in Drug Discovery” 11:35 am - 11:50 am SAPA-NE 2000-2001 Outstanding Contribution Awards 11:50 am - 1:30 pm Lunch Afternoon Session (Plenary Speeches) Host: Dr. Yaping Hong, Associate Research Fellow, Sepracor Inc. 1:30 pm - 2:10 pm Dr. Ken Korzekwa, VP of Research, Camitro Corporation “Modeling Biochemistry’s Versatile Processes: Cytochrome P450 Models for Drug Discovery and Development” 2:10 pm - 2:50 pm Dr. Bingfang Yan, D.V.M., Associate Professor, Dept. of Biomedical Sciences, University of Rhode Island “Regulation of Drug-Metabolizing Enzymes by Nuclear Receptor Activation: Serious Considerations in Drug Development” 2:50 pm - 3:10 pm Coffee Break 3:10pm - 3:50 pm Dr. Kelvin W. Chan, Head, eADME, Drug Metabolism & Pharmacokinetics, Aventis Pharmaceuticals, Inc. “The Role of ADME/PK in Drug Discovery”3:50 pm - 4:30 pm Dr. Chris H. Senanayake, Senior Director of Chemical Process Research, Sepracor Inc. “Rapid Access to Drug Synthesis via Catalytic and Asymmetric Processes”
“Small Molecule Drug Discovery at Genzyme Corporation” 5:30 pm – 6:30 pm Social Hour Parallel Session Section Chair: Dr. Jun Xian, Genome Therapeutics Corporation 10:00 am - 5:30 pm Trade Exposition of Novel Technology and New Products for Drug Discovery
Host: Dr. Jun Huangpu, MBA, Harvard Business School 9:10 am – 9:50 am Dr. Roland R. Franke, CEO, Natural Pharmaceuticals, Inc. “Success Factors in Technology Commercialization”9:50 am - 10:30 am Dr. Joseph C. Hogan, President and CEO, Alveus Systems, Inc. “A Molecular Level Systems Engineering Approach to Chemical Markets”
“A Career Transition from Science to Business Development - from Big Pharma to Biotech” 12:00 pm - 1:30 pm Lunch Afternoon Session (Plenary Speeches and Penal Discussions)Host: Dr. Yibin Xiang, Director of Chemistry, Genome Therapeutics Corp., Chair of SAPA-NE Advisory Committee 1:30 pm - 2:10 pm Dr. Kenneth I. Kaitin, Director, Tufts Center for the Study of Drug Development “The Changing Environment for Pharmaceutical Innovation”2:10 pm - 2:50 pm Ms. Rongling Deng, WHO Fellow, Tufts Center for the Study of Drug Development, SDA Officer
2:50 pm – 3:00 pm Coffee Break 3:00 pm - 5:30 pm Discussion with Delegation of China Senior Pharmaceutical Executives and Government Regulatory Agencies Wang Jian Ping, Director, Dept. of Biotech. and Pharmaceutical Science & Technology Commission of Shanghai Municipality Fu Da Xu, Assoc. Director of Project Management, Shanghai Center of Research & Development of New Drugs Wang Huisheng, VP, Shanghai Clone Biotech. Co., Ltd. Jiang Guangping, General Manager, Biolink Informatics Inc. Cheng Yong, Vice President of Marketing & Sale, United Gene Holdings, Ltd. Chen Qi Yu, VP, Shanghai Fortune Industrial Joint-Stock Co., Ltd. Dr. Qi Bao, Senior Consultant and Manager Pharmaceuticals Group, China Concept
Section Chair: Dr. Jun Xian, Genome Therapeutics Corporation 10:00 am - 5:30 pm Trade Exposition of Novel Technology and New Products for Drug Discovery
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