A review of ssri-induced indifference



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Ven draft 11 july
Yee Chin et al.18 2015

Anhedonia in depressed

Cross-sectional study comparing anhedonia

111 depressed patients on SSRIs (recruited from outpatient clinic) compared with health normal (visitors of family members of above patients)

Assessed with Mini International Neuropsychiatric Interview, Beck’s Depression Index and Snaith-Hamilton Pleasure Scale

Total SHAPS score for anhedonia higher in depressed group on SSRI with 9 out of 14 items significant difference. (interest/past times, social interaction and sensory experience and food/drink

Temporal correlation- causality cannot be concluded
Visitors and family members as control group may


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