A review of ssri-induced indifference



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Ven draft 11 july
Price et al.20 2009

Emotional side effects of SSRI

Qualitative study: Thirty-eight semi-structured individual interviews

38 in study from patients recruited from GPs, psychiatrists and posters
(19 patients) in Oxfordshire, and web forums

30 currently taking SSRIs (79%)

Most participants reported reduction in intensity of emotions

Significant selection bias with 19 out of 38 from recruitment posters

Opbroeket al.21 2002

Emotional blunting associated with SSRI-induced sexual dysfunction..

Association cross-sectional study- 15 patients reporting SSRI induced sexual dysfunction complete Laukes Emotional Intensity Scale

Recruited from study of patients reporting SSRI-induced sexual dysfunction

Laukes Emotional Intensity Scale questionnaire

80% of patients with SSRI-induced sexual dysfunction also described clinically significant blunting of several emotions

Recruitment of patients, small number and out of study of those reporting sexual dysfunction
recruitment selection not described


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